DE3681719D1 - Polycyclische chinolin-, naphthyridin- und pyrazinopyridinabkoemmlinge. - Google Patents

Polycyclische chinolin-, naphthyridin- und pyrazinopyridinabkoemmlinge.

Info

Publication number
DE3681719D1
DE3681719D1 DE8686904508T DE3681719T DE3681719D1 DE 3681719 D1 DE3681719 D1 DE 3681719D1 DE 8686904508 T DE8686904508 T DE 8686904508T DE 3681719 T DE3681719 T DE 3681719T DE 3681719 D1 DE3681719 D1 DE 3681719D1
Authority
DE
Germany
Prior art keywords
polycyclic
pyrazinopyridine
chinoline
naphthyridine
collectors
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8686904508T
Other languages
English (en)
Inventor
Kumar Ganguly
Herbert Schwerdt
James Friary
Ira Siegel
Randall Smith
Ann Seidl
J Sybertz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sharp and Dohme Corp
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Application granted granted Critical
Publication of DE3681719D1 publication Critical patent/DE3681719D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D221/00Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04Ortho- or peri-condensed ring systems
    • C07D221/06Ring systems of three rings
    • C07D221/16Ring systems of three rings containing carbocyclic rings other than six-membered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/14Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/12Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D495/14Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Luminescent Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Quinoline Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
DE8686904508T 1985-06-13 1986-06-13 Polycyclische chinolin-, naphthyridin- und pyrazinopyridinabkoemmlinge. Expired - Fee Related DE3681719D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US74486585A 1985-06-13 1985-06-13
US86178886A 1986-05-15 1986-05-15
PCT/US1986/001269 WO1986007359A2 (en) 1985-06-13 1986-06-13 Polycyclic quinoline, naphthyridine and pyrazinopyridine derivatives

Publications (1)

Publication Number Publication Date
DE3681719D1 true DE3681719D1 (de) 1991-10-31

Family

ID=27114362

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8686904508T Expired - Fee Related DE3681719D1 (de) 1985-06-13 1986-06-13 Polycyclische chinolin-, naphthyridin- und pyrazinopyridinabkoemmlinge.

Country Status (19)

Country Link
EP (1) EP0229823B1 (de)
JP (1) JPH0762017B2 (de)
KR (1) KR900004831B1 (de)
AT (1) ATE67764T1 (de)
AU (1) AU591922B2 (de)
CA (1) CA1306255C (de)
DE (1) DE3681719D1 (de)
DK (1) DK70687A (de)
GR (1) GR861530B (de)
HK (1) HK94694A (de)
HU (1) HU203098B (de)
IE (1) IE60420B1 (de)
IL (1) IL79110A0 (de)
MY (1) MY101808A (de)
NO (1) NO168177C (de)
NZ (1) NZ216519A (de)
OA (1) OA08480A (de)
PT (1) PT82752B (de)
WO (1) WO1986007359A2 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3609795A1 (de) * 1986-03-22 1987-09-24 Goedecke Ag Pyrido(4,3-b)(1,6)naphthyridin-derivate, verfahren zu deren herstellung und deren verwendung
US5366971A (en) * 1987-11-09 1994-11-22 Sandoz Ltd. Use of 11,28-dioxa-4-azatricyclo[22.3.1.04,9 ]octacos-18-ene derivatives and pharmaceutical compositions containing them
BR9507311A (pt) * 1994-04-08 1997-10-07 Prevue International Inc Guia de programa de rolagem interativo
DE69524251T2 (de) * 1994-06-14 2002-07-11 Dainippon Pharmaceutical Co Neue verbindung, verfahren zu ihrer herstellung und antitumormittel
DE60013994T2 (de) * 1999-08-30 2005-10-06 Maruishi Pharmaceutical Co.Ltd. 1,2-Disubstituierte 1,4-Dihydro-4-oxochinolin-Verbindungen
US9625475B2 (en) 2008-09-29 2017-04-18 Abbvie Inc. Indole and indoline derivatives and methods of use thereof
HU231285B1 (hu) 2018-04-18 2022-08-28 Printnet Kereskedelmi És Szolgáltató Kft. A miozin-2-izoformákat szelektíven gátló, gyógyászatilag hatásos vegyületek

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH498841A (fr) * 1967-07-13 1970-11-15 Inst Farmaceutyczny Procédé de préparation de benzo-(b,1,8)-naphtyridones-5 substituées
DE2803541A1 (de) * 1978-01-27 1979-08-02 Sandoz Ag Neue chinolinderivate, ihre herstellung und verwendung
US4680298A (en) * 1983-05-31 1987-07-14 Schering Corporation Tricyclic anti-allergy and use as anti-inflammatory agents

Also Published As

Publication number Publication date
PT82752A (en) 1986-07-01
EP0229823B1 (de) 1991-09-25
WO1986007359A2 (en) 1986-12-18
EP0229823A1 (de) 1987-07-29
DK70687D0 (da) 1987-02-12
HUT42482A (en) 1987-07-28
ATE67764T1 (de) 1991-10-15
AU6122486A (en) 1987-01-07
HK94694A (en) 1994-09-16
CA1306255C (en) 1992-08-11
MY101808A (en) 1992-01-31
GR861530B (en) 1986-12-31
NO870564D0 (no) 1987-02-12
KR900004831B1 (ko) 1990-07-07
NO168177C (no) 1992-01-22
JPH0762017B2 (ja) 1995-07-05
DK70687A (da) 1987-02-12
IL79110A0 (en) 1986-09-30
WO1986007359A3 (en) 1987-04-09
NZ216519A (en) 1989-02-24
NO870564L (no) 1987-02-12
AU591922B2 (en) 1989-12-21
NO168177B (no) 1991-10-14
KR870700622A (ko) 1987-12-30
OA08480A (en) 1988-07-29
IE861565L (en) 1986-12-13
HU203098B (en) 1991-05-28
IE60420B1 (en) 1994-07-13
JPS63500518A (ja) 1988-02-25
PT82752B (pt) 1988-12-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee