ATE67764T1 - Polycyclische chinolin-, naphthyridin- und pyrazinopyridinabkoemmlinge. - Google Patents

Polycyclische chinolin-, naphthyridin- und pyrazinopyridinabkoemmlinge.

Info

Publication number
ATE67764T1
ATE67764T1 AT86904508T AT86904508T ATE67764T1 AT E67764 T1 ATE67764 T1 AT E67764T1 AT 86904508 T AT86904508 T AT 86904508T AT 86904508 T AT86904508 T AT 86904508T AT E67764 T1 ATE67764 T1 AT E67764T1
Authority
AT
Austria
Prior art keywords
naphthyridine
polycyclic
pyrazinopyridine
derivatives
polycyclic quinoline
Prior art date
Application number
AT86904508T
Other languages
English (en)
Inventor
Ashit Kumar Ganguly
John Herbert Schwerdt
Richard James Friary
Marvin Ira Siegel
Sidney Randall Smith
Vera Ann Seidl
Edmund J Sybertz
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Application granted granted Critical
Publication of ATE67764T1 publication Critical patent/ATE67764T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D221/00Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04Ortho- or peri-condensed ring systems
    • C07D221/06Ring systems of three rings
    • C07D221/16Ring systems of three rings containing carbocyclic rings other than six-membered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/14Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/12Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D495/14Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Transplantation (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Cardiology (AREA)
  • Pulmonology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Luminescent Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Quinoline Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
AT86904508T 1985-06-13 1986-06-13 Polycyclische chinolin-, naphthyridin- und pyrazinopyridinabkoemmlinge. ATE67764T1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US74486585A 1985-06-13 1985-06-13
US86178886A 1986-05-15 1986-05-15
EP86904508A EP0229823B1 (de) 1985-06-13 1986-06-13 Polycyclische chinolin-, naphthyridin- und pyrazinopyridinabkömmlinge
PCT/US1986/001269 WO1986007359A2 (en) 1985-06-13 1986-06-13 Polycyclic quinoline, naphthyridine and pyrazinopyridine derivatives

Publications (1)

Publication Number Publication Date
ATE67764T1 true ATE67764T1 (de) 1991-10-15

Family

ID=27114362

Family Applications (1)

Application Number Title Priority Date Filing Date
AT86904508T ATE67764T1 (de) 1985-06-13 1986-06-13 Polycyclische chinolin-, naphthyridin- und pyrazinopyridinabkoemmlinge.

Country Status (19)

Country Link
EP (1) EP0229823B1 (de)
JP (1) JPH0762017B2 (de)
KR (1) KR900004831B1 (de)
AT (1) ATE67764T1 (de)
AU (1) AU591922B2 (de)
CA (1) CA1306255C (de)
DE (1) DE3681719D1 (de)
DK (1) DK70687A (de)
GR (1) GR861530B (de)
HK (1) HK94694A (de)
HU (1) HU203098B (de)
IE (1) IE60420B1 (de)
IL (1) IL79110A0 (de)
MY (1) MY101808A (de)
NO (1) NO168177C (de)
NZ (1) NZ216519A (de)
OA (1) OA08480A (de)
PT (1) PT82752B (de)
WO (1) WO1986007359A2 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3609795A1 (de) * 1986-03-22 1987-09-24 Goedecke Ag Pyrido(4,3-b)(1,6)naphthyridin-derivate, verfahren zu deren herstellung und deren verwendung
US5366971A (en) * 1987-11-09 1994-11-22 Sandoz Ltd. Use of 11,28-dioxa-4-azatricyclo[22.3.1.04,9 ]octacos-18-ene derivatives and pharmaceutical compositions containing them
JPH10501932A (ja) * 1994-04-08 1998-02-17 プレビュー インターナショナル, インコーポレイテッド インタラクティブスクロールプログラムガイド
BR9508037A (pt) * 1994-06-14 1997-09-16 Dainippon Pharmaceutical Co Derivados de piridona-ácido carboxilico agente anti-tumor composição farmacológica e processo para preparar derivados de piridona-ácido carboxilico
US6541470B1 (en) * 1999-08-30 2003-04-01 Maruishi Pharmaceutical Co., Ltd. 1,2-disubstituted 1,4-dihydro-4-oxoquinoline compounds
US9625475B2 (en) 2008-09-29 2017-04-18 Abbvie Inc. Indole and indoline derivatives and methods of use thereof
HU231285B1 (hu) 2018-04-18 2022-08-28 Printnet Kereskedelmi És Szolgáltató Kft. A miozin-2-izoformákat szelektíven gátló, gyógyászatilag hatásos vegyületek

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1585099A (de) * 1967-07-13 1970-01-09
DE2803541A1 (de) * 1978-01-27 1979-08-02 Sandoz Ag Neue chinolinderivate, ihre herstellung und verwendung
US4680298A (en) * 1983-05-31 1987-07-14 Schering Corporation Tricyclic anti-allergy and use as anti-inflammatory agents

Also Published As

Publication number Publication date
AU591922B2 (en) 1989-12-21
PT82752A (en) 1986-07-01
WO1986007359A2 (en) 1986-12-18
NO168177C (no) 1992-01-22
MY101808A (en) 1992-01-31
KR870700622A (ko) 1987-12-30
EP0229823A1 (de) 1987-07-29
HU203098B (en) 1991-05-28
HK94694A (en) 1994-09-16
OA08480A (en) 1988-07-29
IL79110A0 (en) 1986-09-30
GR861530B (en) 1986-12-31
KR900004831B1 (ko) 1990-07-07
EP0229823B1 (de) 1991-09-25
NZ216519A (en) 1989-02-24
DE3681719D1 (de) 1991-10-31
IE861565L (en) 1986-12-13
NO168177B (no) 1991-10-14
DK70687D0 (da) 1987-02-12
IE60420B1 (en) 1994-07-13
NO870564L (no) 1987-02-12
DK70687A (da) 1987-02-12
AU6122486A (en) 1987-01-07
NO870564D0 (no) 1987-02-12
CA1306255C (en) 1992-08-11
JPS63500518A (ja) 1988-02-25
WO1986007359A3 (en) 1987-04-09
HUT42482A (en) 1987-07-28
PT82752B (pt) 1988-12-15
JPH0762017B2 (ja) 1995-07-05

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee