PT82752B - Processo para a preparacao de derivados policiclicos de quinolina, naftiridina e pirazinopiridina - Google Patents

Processo para a preparacao de derivados policiclicos de quinolina, naftiridina e pirazinopiridina

Info

Publication number
PT82752B
PT82752B PT82752A PT8275286A PT82752B PT 82752 B PT82752 B PT 82752B PT 82752 A PT82752 A PT 82752A PT 8275286 A PT8275286 A PT 8275286A PT 82752 B PT82752 B PT 82752B
Authority
PT
Portugal
Prior art keywords
pyrazinopyridine
naftiridine
quinoline
preparation
polycyclic derivatives
Prior art date
Application number
PT82752A
Other languages
English (en)
Other versions
PT82752A (en
Inventor
Ashit Kumar Ganguly
Edmund J Sybertz
Marvin Ira Siegel
Sidney Randall Smith
John Herbert Schwerdt
Richard James Friary
Vera Ann Seidl
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of PT82752A publication Critical patent/PT82752A/pt
Publication of PT82752B publication Critical patent/PT82752B/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D221/00Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04Ortho- or peri-condensed ring systems
    • C07D221/06Ring systems of three rings
    • C07D221/16Ring systems of three rings containing carbocyclic rings other than six-membered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/14Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/12Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D495/14Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Luminescent Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Quinoline Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
PT82752A 1985-06-13 1986-06-12 Processo para a preparacao de derivados policiclicos de quinolina, naftiridina e pirazinopiridina PT82752B (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US74486585A 1985-06-13 1985-06-13
US86178886A 1986-05-15 1986-05-15

Publications (2)

Publication Number Publication Date
PT82752A PT82752A (en) 1986-07-01
PT82752B true PT82752B (pt) 1988-12-15

Family

ID=27114362

Family Applications (1)

Application Number Title Priority Date Filing Date
PT82752A PT82752B (pt) 1985-06-13 1986-06-12 Processo para a preparacao de derivados policiclicos de quinolina, naftiridina e pirazinopiridina

Country Status (19)

Country Link
EP (1) EP0229823B1 (pt)
JP (1) JPH0762017B2 (pt)
KR (1) KR900004831B1 (pt)
AT (1) ATE67764T1 (pt)
AU (1) AU591922B2 (pt)
CA (1) CA1306255C (pt)
DE (1) DE3681719D1 (pt)
DK (1) DK70687A (pt)
GR (1) GR861530B (pt)
HK (1) HK94694A (pt)
HU (1) HU203098B (pt)
IE (1) IE60420B1 (pt)
IL (1) IL79110A0 (pt)
MY (1) MY101808A (pt)
NO (1) NO168177C (pt)
NZ (1) NZ216519A (pt)
OA (1) OA08480A (pt)
PT (1) PT82752B (pt)
WO (1) WO1986007359A2 (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3609795A1 (de) * 1986-03-22 1987-09-24 Goedecke Ag Pyrido(4,3-b)(1,6)naphthyridin-derivate, verfahren zu deren herstellung und deren verwendung
US5366971A (en) * 1987-11-09 1994-11-22 Sandoz Ltd. Use of 11,28-dioxa-4-azatricyclo[22.3.1.04,9 ]octacos-18-ene derivatives and pharmaceutical compositions containing them
WO1995028055A1 (en) * 1994-04-08 1995-10-19 Prevue International, Inc. Interactive scroll program guide
SK281341B6 (sk) * 1994-06-14 2001-02-12 Dainippon Pharmaceutical Co., Ltd. Deriváty pyridónkarboxylovej kyseliny alebo jej farmaceuticky prijateľných solí, spôsob ich prípravy a farmakologické prostriedky ich obsahujúce
ES2228370T3 (es) * 1999-08-30 2005-04-16 Maruishi Pharmaceutical Co., Ltd. Compuestos de 1,4-dihidro-4-oxoquinolina 1,2-disustituidos.
US9625475B2 (en) 2008-09-29 2017-04-18 Abbvie Inc. Indole and indoline derivatives and methods of use thereof
HU231285B1 (hu) 2018-04-18 2022-08-28 Printnet Kereskedelmi És Szolgáltató Kft. A miozin-2-izoformákat szelektíven gátló, gyógyászatilag hatásos vegyületek

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH498841A (fr) * 1967-07-13 1970-11-15 Inst Farmaceutyczny Procédé de préparation de benzo-(b,1,8)-naphtyridones-5 substituées
DE2803541A1 (de) * 1978-01-27 1979-08-02 Sandoz Ag Neue chinolinderivate, ihre herstellung und verwendung
US4680298A (en) * 1983-05-31 1987-07-14 Schering Corporation Tricyclic anti-allergy and use as anti-inflammatory agents

Also Published As

Publication number Publication date
EP0229823A1 (en) 1987-07-29
JPS63500518A (ja) 1988-02-25
AU591922B2 (en) 1989-12-21
MY101808A (en) 1992-01-31
HUT42482A (en) 1987-07-28
IE60420B1 (en) 1994-07-13
WO1986007359A3 (en) 1987-04-09
EP0229823B1 (en) 1991-09-25
KR870700622A (ko) 1987-12-30
KR900004831B1 (ko) 1990-07-07
AU6122486A (en) 1987-01-07
DK70687D0 (da) 1987-02-12
PT82752A (en) 1986-07-01
NO870564L (no) 1987-02-12
HU203098B (en) 1991-05-28
NO168177B (no) 1991-10-14
NO870564D0 (no) 1987-02-12
IE861565L (en) 1986-12-13
NO168177C (no) 1992-01-22
CA1306255C (en) 1992-08-11
GR861530B (en) 1986-12-31
DK70687A (da) 1987-02-12
IL79110A0 (en) 1986-09-30
DE3681719D1 (de) 1991-10-31
WO1986007359A2 (en) 1986-12-18
NZ216519A (en) 1989-02-24
HK94694A (en) 1994-09-16
OA08480A (en) 1988-07-29
JPH0762017B2 (ja) 1995-07-05
ATE67764T1 (de) 1991-10-15

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Effective date: 19961130