DE3680749D1 - Makrolid-antibiotikaderivate. - Google Patents

Makrolid-antibiotikaderivate.

Info

Publication number
DE3680749D1
DE3680749D1 DE8686115523T DE3680749T DE3680749D1 DE 3680749 D1 DE3680749 D1 DE 3680749D1 DE 8686115523 T DE8686115523 T DE 8686115523T DE 3680749 T DE3680749 T DE 3680749T DE 3680749 D1 DE3680749 D1 DE 3680749D1
Authority
DE
Germany
Prior art keywords
antibiotic derivatives
macrolid
macrolid antibiotic
derivatives
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8686115523T
Other languages
English (en)
Inventor
Hermann Faubl
Robert G Stein
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Application granted granted Critical
Publication of DE3680749D1 publication Critical patent/DE3680749D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H23/00—Compounds containing boron, silicon, or a metal, e.g. chelates, vitamin B12
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
DE8686115523T 1985-11-12 1986-11-08 Makrolid-antibiotikaderivate. Expired - Fee Related DE3680749D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/796,818 US4640910A (en) 1985-11-12 1985-11-12 Erythromycin A silylated compounds and method of use

Publications (1)

Publication Number Publication Date
DE3680749D1 true DE3680749D1 (de) 1991-09-12

Family

ID=25169134

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8686115523T Expired - Fee Related DE3680749D1 (de) 1985-11-12 1986-11-08 Makrolid-antibiotikaderivate.

Country Status (14)

Country Link
US (1) US4640910A (de)
EP (1) EP0222353B1 (de)
JP (1) JPS62120397A (de)
KR (1) KR870005004A (de)
AT (1) ATE66001T1 (de)
AU (1) AU598486B2 (de)
CA (1) CA1282059C (de)
DE (1) DE3680749D1 (de)
DK (1) DK536186A (de)
ES (1) ES2002212A6 (de)
GR (1) GR862517B (de)
IL (1) IL80146A0 (de)
NZ (1) NZ217665A (de)
ZA (1) ZA867294B (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5175150A (en) * 1985-08-31 1992-12-29 Kitasato, Kenkyusho Erythromycin derivative
EP0260938B1 (de) * 1986-09-18 1992-12-09 Taisho Pharmaceutical Co. Ltd Erythromycin-A-Derivate und Verfahren zu ihrer Herstellung
KR960000434B1 (ko) * 1986-12-17 1996-01-06 다이쇼 세이야꾸 가부시끼가이샤 에리스로마이신 a유도체 및 그의 제조 방법
US4808411A (en) * 1987-06-05 1989-02-28 Abbott Laboratories Antibiotic-polymer compositions
JP2654194B2 (ja) * 1989-06-20 1997-09-17 メルシャン株式会社 アンゴラマイシン誘導体
EP0559896B1 (de) * 1990-11-28 1997-08-27 Taisho Pharmaceutical Co. Ltd 6-0-methylerythromycin a-derivat
IL104437A (en) * 1992-01-21 1997-03-18 Abbott Lab 4)-deoxyerythromycin derivatives
US5872229A (en) 1995-11-21 1999-02-16 Abbott Laboratories Process for 6-O-alkylation of erythromycin derivatives
US5837829A (en) * 1996-04-02 1998-11-17 Abbott Laboratories 9-oximesilyl erythromycin a derivatives
US5712253A (en) * 1996-06-18 1998-01-27 Abbott Laboratories Macrocyclic 13-membered ring derivatives of erythromycins A and B
US5929219A (en) 1997-09-10 1999-07-27 Abbott Laboratories 9-hydrazone and 9-azine erythromycin derivatives and a process of making the same
US5892008A (en) * 1997-12-16 1999-04-06 Abbott Laboratories Process for the preparation of 6-O-methyl erythromycin a using 9-hydroxy erythromycin derivatives
WO1999032500A2 (en) * 1997-12-22 1999-07-01 Biochemie S.A. Intermediates in macrolide production
GB9915745D0 (en) * 1999-07-06 1999-09-08 Biochemie Sa Organic compounds
CZ20021999A3 (cs) 1999-12-16 2003-02-12 Teva Pharmaceutical Industries Ltd. Způsob přípravy klaritromycinových polymorfních forem a nového polymorfu IV
HUP0204252A3 (en) 2000-01-11 2003-04-28 Teva Pharma Process for preparing clarithromycin polymorphs and pharmaceutical compositions containing them
HUP0302466A2 (hu) * 2000-02-29 2003-11-28 Teva Pharmaceutical Industries Ltd. Eljárások clarithromycin, clarithromycin intermedier, gyakorlatilag oximmentes clarithromycin és ezt tartalmazó gyógyszerkészítmény előállítására
KR100361397B1 (ko) * 2000-03-15 2002-11-23 한미약품공업 주식회사 에리스로마이신 에이 9-오-트로필옥심 유도체를 이용한클라리스로마이신의 제조방법
DK1267840T3 (da) * 2000-03-28 2009-09-07 Sandoz Ag Granulerede partikler med maskeret smag

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2746956A (en) * 1953-06-16 1956-05-22 Dow Corning Method of silylating organic compounds
US4331803A (en) * 1980-06-04 1982-05-25 Taisho Pharmaceutical Co., Ltd. Novel erythromycin compounds
US4336368A (en) * 1981-04-20 1982-06-22 Pfizer Inc. 4 Deoxy-4-methylene oleandomycin and derivatives thereof
JPS5896095A (ja) * 1981-11-30 1983-06-07 Taisho Pharmaceut Co Ltd １１−ｏ−アルキルエリスロマイシンａ誘導体
US4382085A (en) * 1982-03-01 1983-05-03 Pfizer Inc. 4"-Epi erythromycin A and derivatives thereof as useful antibacterial agents
US4382086A (en) * 1982-03-01 1983-05-03 Pfizer Inc. 9-Dihydro-11,12-ketal derivatives of erythromycin A and epi-erythromycin A
US4429116A (en) * 1982-12-27 1984-01-31 Pfizer Inc. Alkylated oleandomycin containing compounds

Also Published As

Publication number Publication date
NZ217665A (en) 1990-04-26
AU6491686A (en) 1987-05-14
ZA867294B (en) 1987-05-27
JPH0312078B2 (de) 1991-02-19
AU598486B2 (en) 1990-06-28
JPS62120397A (ja) 1987-06-01
EP0222353A3 (en) 1987-09-23
ES2002212A6 (es) 1988-07-16
ATE66001T1 (de) 1991-08-15
EP0222353B1 (de) 1991-08-07
US4640910A (en) 1987-02-03
DK536186A (da) 1987-05-13
EP0222353A2 (de) 1987-05-20
KR870005004A (ko) 1987-06-04
GR862517B (en) 1987-02-09
IL80146A0 (en) 1986-12-31
CA1282059C (en) 1991-03-26
DK536186D0 (da) 1986-11-10

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee