GR862517B - Macrolide antibiotic derivatives - Google Patents

Macrolide antibiotic derivatives

Info

Publication number
GR862517B
GR862517B GR862517A GR860102517A GR862517B GR 862517 B GR862517 B GR 862517B GR 862517 A GR862517 A GR 862517A GR 860102517 A GR860102517 A GR 860102517A GR 862517 B GR862517 B GR 862517B
Authority
GR
Greece
Prior art keywords
macrolide antibiotic
antibiotic derivatives
derivatives
compounds
macrolide
Prior art date
Application number
GR862517A
Other languages
English (en)
Inventor
Faubl Hermann
Robert G Stein
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of GR862517B publication Critical patent/GR862517B/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H23/00—Compounds containing boron, silicon, or a metal, e.g. chelates, vitamin B12
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GR862517A 1985-11-12 1986-10-07 Macrolide antibiotic derivatives GR862517B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/796,818 US4640910A (en) 1985-11-12 1985-11-12 Erythromycin A silylated compounds and method of use

Publications (1)

Publication Number Publication Date
GR862517B true GR862517B (en) 1987-02-09

Family

ID=25169134

Family Applications (1)

Application Number Title Priority Date Filing Date
GR862517A GR862517B (en) 1985-11-12 1986-10-07 Macrolide antibiotic derivatives

Country Status (14)

Country Link
US (1) US4640910A (el)
EP (1) EP0222353B1 (el)
JP (1) JPS62120397A (el)
KR (1) KR870005004A (el)
AT (1) ATE66001T1 (el)
AU (1) AU598486B2 (el)
CA (1) CA1282059C (el)
DE (1) DE3680749D1 (el)
DK (1) DK536186A (el)
ES (1) ES2002212A6 (el)
GR (1) GR862517B (el)
IL (1) IL80146A0 (el)
NZ (1) NZ217665A (el)
ZA (1) ZA867294B (el)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5175150A (en) * 1985-08-31 1992-12-29 Kitasato, Kenkyusho Erythromycin derivative
EP0260938B1 (en) * 1986-09-18 1992-12-09 Taisho Pharmaceutical Co. Ltd Erythromycin a derivatives and method for preparing the same
KR960000434B1 (ko) * 1986-12-17 1996-01-06 다이쇼 세이야꾸 가부시끼가이샤 에리스로마이신 a유도체 및 그의 제조 방법
US4808411A (en) * 1987-06-05 1989-02-28 Abbott Laboratories Antibiotic-polymer compositions
JP2654194B2 (ja) * 1989-06-20 1997-09-17 メルシャン株式会社 アンゴラマイシン誘導体
KR0166096B1 (ko) * 1990-11-28 1999-01-15 우에하라 아키라 6-0-메틸에리쓰로마이신 a 유도체
DE69317877T2 (de) * 1992-01-21 1998-10-29 Abbott Lab 4''-deoxyerythromycinderivate
US5872229A (en) 1995-11-21 1999-02-16 Abbott Laboratories Process for 6-O-alkylation of erythromycin derivatives
US5837829A (en) * 1996-04-02 1998-11-17 Abbott Laboratories 9-oximesilyl erythromycin a derivatives
US5712253A (en) * 1996-06-18 1998-01-27 Abbott Laboratories Macrocyclic 13-membered ring derivatives of erythromycins A and B
US5929219A (en) 1997-09-10 1999-07-27 Abbott Laboratories 9-hydrazone and 9-azine erythromycin derivatives and a process of making the same
US5892008A (en) * 1997-12-16 1999-04-06 Abbott Laboratories Process for the preparation of 6-O-methyl erythromycin a using 9-hydroxy erythromycin derivatives
AU2274799A (en) * 1997-12-22 1999-07-12 Biochemie S.A. Intermediates in macrolide production
GB9915745D0 (en) * 1999-07-06 1999-09-08 Biochemie Sa Organic compounds
EP1254146B1 (en) 1999-12-16 2005-08-24 Teva Pharmaceutical Industries Ltd. Processes for preparing clarithromycin polymorphs and novel polymorph iv
CA2397092A1 (en) 2000-01-11 2001-07-19 Teva Pharmaceutical Industries Ltd. Processes for preparing clarithromycin polymorphs
HUP0302466A2 (hu) * 2000-02-29 2003-11-28 Teva Pharmaceutical Industries Ltd. Eljárások clarithromycin, clarithromycin intermedier, gyakorlatilag oximmentes clarithromycin és ezt tartalmazó gyógyszerkészítmény előállítására
KR100361397B1 (ko) * 2000-03-15 2002-11-23 한미약품공업 주식회사 에리스로마이신 에이 9-오-트로필옥심 유도체를 이용한클라리스로마이신의 제조방법
DE60138876D1 (de) * 2000-03-28 2009-07-16 Sandoz Ag Geschmackmaskierte granulierte teilchen

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2746956A (en) * 1953-06-16 1956-05-22 Dow Corning Method of silylating organic compounds
US4331803A (en) * 1980-06-04 1982-05-25 Taisho Pharmaceutical Co., Ltd. Novel erythromycin compounds
US4336368A (en) * 1981-04-20 1982-06-22 Pfizer Inc. 4 Deoxy-4-methylene oleandomycin and derivatives thereof
JPS5896095A (ja) * 1981-11-30 1983-06-07 Taisho Pharmaceut Co Ltd １１−ｏ−アルキルエリスロマイシンａ誘導体
US4382085A (en) * 1982-03-01 1983-05-03 Pfizer Inc. 4"-Epi erythromycin A and derivatives thereof as useful antibacterial agents
US4382086A (en) * 1982-03-01 1983-05-03 Pfizer Inc. 9-Dihydro-11,12-ketal derivatives of erythromycin A and epi-erythromycin A
US4429116A (en) * 1982-12-27 1984-01-31 Pfizer Inc. Alkylated oleandomycin containing compounds

Also Published As

Publication number Publication date
AU6491686A (en) 1987-05-14
EP0222353A3 (en) 1987-09-23
KR870005004A (ko) 1987-06-04
IL80146A0 (en) 1986-12-31
ATE66001T1 (de) 1991-08-15
ZA867294B (en) 1987-05-27
ES2002212A6 (es) 1988-07-16
AU598486B2 (en) 1990-06-28
CA1282059C (en) 1991-03-26
EP0222353B1 (en) 1991-08-07
DK536186A (da) 1987-05-13
US4640910A (en) 1987-02-03
EP0222353A2 (en) 1987-05-20
DK536186D0 (da) 1986-11-10
JPH0312078B2 (el) 1991-02-19
DE3680749D1 (de) 1991-09-12
JPS62120397A (ja) 1987-06-01
NZ217665A (en) 1990-04-26

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