DE3675408D1 - Phenylcarbamate. - Google Patents

Phenylcarbamate.

Info

Publication number
DE3675408D1
DE3675408D1 DE8686102812T DE3675408T DE3675408D1 DE 3675408 D1 DE3675408 D1 DE 3675408D1 DE 8686102812 T DE8686102812 T DE 8686102812T DE 3675408 T DE3675408 T DE 3675408T DE 3675408 D1 DE3675408 D1 DE 3675408D1
Authority
DE
Germany
Prior art keywords
sub
phenylcarbamate
pharmaceuticals
useful
phenyl carbamates
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8686102812T
Other languages
English (en)
Inventor
Rosin Marta Prof Weinstock
Michael Chorev
Zeev Tashma
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Proterra AG
Original Assignee
Proterra AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=11055728&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE3675408(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Proterra AG filed Critical Proterra AG
Application granted granted Critical
Publication of DE3675408D1 publication Critical patent/DE3675408D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/40—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of six-membered aromatic rings
    • C07C271/42—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of six-membered aromatic rings with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C333/00—Derivatives of thiocarbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C333/14—Dithiocarbamic acids; Derivatives thereof
    • C07C333/30—Dithiocarbamic acids; Derivatives thereof having sulfur atoms of dithiocarbamic groups bound to other sulfur atoms
    • C07C333/32—Thiuramsulfides; Thiurampolysulfides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
DE8686102812T 1985-03-05 1986-03-04 Phenylcarbamate. Expired - Lifetime DE3675408D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL74497A IL74497A (en) 1985-03-05 1985-03-05 Pharmaceutical compositions containing phenyl carbamate derivatives and certain phenyl carbamate derivatives

Publications (1)

Publication Number Publication Date
DE3675408D1 true DE3675408D1 (de) 1990-12-13

Family

ID=11055728

Family Applications (2)

Application Number Title Priority Date Filing Date
DE1998175046 Pending DE19875046I1 (de) 1985-03-05 1986-03-04 Phenylcarbamate
DE8686102812T Expired - Lifetime DE3675408D1 (de) 1985-03-05 1986-03-04 Phenylcarbamate.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE1998175046 Pending DE19875046I1 (de) 1985-03-05 1986-03-04 Phenylcarbamate

Country Status (25)

Country Link
US (1) US4948807A (de)
EP (1) EP0193926B3 (de)
JP (1) JPS61225158A (de)
KR (1) KR940010764B1 (de)
AT (1) ATE58130T1 (de)
AU (1) AU595504B2 (de)
CA (1) CA1284501C (de)
CY (2) CY1748A (de)
DE (2) DE19875046I1 (de)
DK (1) DK172851B1 (de)
ES (1) ES8801193A1 (de)
FI (1) FI87197C (de)
GR (1) GR860586B (de)
HK (1) HK130293A (de)
HU (1) HU201297B (de)
IE (1) IE58838B1 (de)
IL (1) IL74497A (de)
LU (1) LU90312I2 (de)
MY (1) MY137602A (de)
NL (1) NL980031I2 (de)
NZ (1) NZ215348A (de)
PH (1) PH23325A (de)
PL (1) PL146301B1 (de)
PT (1) PT82127B (de)
ZA (1) ZA861653B (de)

Families Citing this family (80)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH667001A5 (de) * 1985-09-03 1988-09-15 Hugo Degen Untermatratze.
HU201906B (en) * 1987-03-04 1991-01-28 Sandoz Ag Process for producing phenyl-carbamate derivative and acid additional salts and pharmaceutical compositions containing them
DE3805744C2 (de) * 1987-03-04 1999-09-23 Novartis Ag Phenylcarbamate zur Hemmung der Acetylcholinesterase
US5091583A (en) * 1990-05-07 1992-02-25 Air Products And Chemicals, Inc. Tertiary amine catalysts for polurethanes
IT1271679B (it) * 1994-07-18 1997-06-04 Mediolanum Farmaceutici Srl Derivati del fenilcarbammato atti all'impiego come anticolinesterasici
US20100210590A1 (en) * 1995-09-27 2010-08-19 Northwestern University Compositions and treatments for seizure-related disorders
US5965571A (en) * 1996-08-22 1999-10-12 New York University Cholinesterase inhibitors for treatment of Parkinson's disease
EP1535902B1 (de) 1996-12-18 2007-11-07 Teva Pharmaceutical Industries, Ltd. Aminoindanderivate
DK0951284T3 (da) * 1996-12-18 2004-02-16 Teva Pharma Phenylethylminderivater
US6251938B1 (en) 1996-12-18 2001-06-26 Teva Pharmaceutical Industries, Ltd., Phenylethylamine derivatives
WO1998031356A1 (en) * 1997-01-17 1998-07-23 Takeda Chemical Industries, Ltd. Idebenone containing combination agent for treating alzheimer's disease
US5962535A (en) * 1997-01-17 1999-10-05 Takeda Chemical Industries, Ltd. Composition for alzheimer's disease
GB9716879D0 (en) * 1997-08-08 1997-10-15 Shire Int Licensing Bv Treatment of attention deficit disorders
US6316023B1 (en) * 1998-01-12 2001-11-13 Novartis Ag TTS containing an antioxidant
EP1133230A4 (de) * 1998-11-23 2004-05-26 Bonnie M Davis Dosisformulierungen für acetylcholinesterase-inhibitoren
GB9923045D0 (en) * 1999-09-29 1999-12-01 Novartis Ag New oral formulations
US6534541B1 (en) * 1999-10-19 2003-03-18 Novartis Ag Treatment of ocular disorders
KR20090064603A (ko) 2000-01-28 2009-06-19 마텍 바이오싸이언스스 코포레이션 발효기 내에서 진핵 미생물의 고밀도 배양에 의한 고도불포화 지방산을 함유하는 지질의 증진된 생산 방법
EP1311272B1 (de) * 2000-03-03 2006-11-22 Eisai Co., Ltd. Neue methoden unter verwendung von cholinesteraseinhibitoren
US20030153598A1 (en) * 2000-07-25 2003-08-14 Raymond Pratt Methods for treating Parkinson's disease with cholinesterase inhibitors
AU2001257022B2 (en) * 2000-04-13 2005-02-03 Mayo Foundation For Medical Education And Research Abeta 42 lowering agents
GB0126378D0 (en) * 2001-11-02 2002-01-02 Oxford Biomedica Ltd Antigen
US20040010038A1 (en) * 2002-02-27 2004-01-15 Eran Blaugrund Propargylamino indan derivatives and propargylamino tetralin derivatives as brain-selective MAO inhibitors
WO2003101917A2 (en) * 2002-05-31 2003-12-11 Sun Pharmaceutical Industries Limited A process for the preparation of phenylcarbamates
SI2389937T1 (sl) 2002-06-14 2018-10-30 Toyama Chemical Co., Ltd, Farmacevtska sestava za izboljšanje možganske funkcije
EA010267B1 (ru) 2002-10-07 2008-06-30 Те Риджентс Оф Те Юниверсити Оф Калифорния Модуляция тревоги через блокаду гидролиза анандамида
CZ293014B6 (cs) * 2002-10-24 2004-01-14 Léčiva, A.S. Způsob výroby (-)-(S)-3-[1-(dimethylamino)ethyl]fenyl-N-ethyl-N-methylkarbamátu
DE10301851A1 (de) * 2003-01-17 2004-07-29 Lts Lohmann Therapie-Systeme Ag Verfahren zur medikamentösen Prophylaxe gegen Vergiftungen durch Cholinesterase-Hemmer, sowie hierfür geeignete Wirkstoffe und Arzneimittel
EP1603548A4 (de) * 2003-02-05 2007-10-10 Myriad Genetics Inc Verfahren und zusammensetzung zur behandlung neurodegenerativer erkrankungen
US7521481B2 (en) * 2003-02-27 2009-04-21 Mclaurin Joanne Methods of preventing, treating and diagnosing disorders of protein aggregation
CA2532207A1 (en) * 2003-07-11 2005-07-21 Myriad Genetics, Inc. Pharmaceutical methods, dosing regimes and dosage forms for the treatment of alzheimer's disease
WO2005042475A2 (en) * 2003-10-21 2005-05-12 Sention, Inc. Carbamoyl esters that inhibit cholinesterase and release pharmacologically active agents
ES2347152T3 (es) 2003-11-26 2010-10-26 Pfizer Products Inc. Derivados de aminopirazol como inhibidores de gsk-3.
GB0329284D0 (en) * 2003-12-18 2004-01-21 Avecia Ltd Process
GB2409453A (en) 2003-12-24 2005-06-29 Generics Process for the preparation of aminoalkyl phenylcarbamates
US20050222123A1 (en) 2004-01-27 2005-10-06 North Shore-Long Island Jewish Research Institute Cholinesterase inhibitors for treating inflammation
WO2006001877A2 (en) * 2004-04-13 2006-01-05 Myriad Genetics, Inc. Combination treatment for neurodegenerative disorders comprising r-flurbiprofen
WO2006020850A2 (en) * 2004-08-11 2006-02-23 Myriad Genetics, Inc. Pharmaceutical composition and method for treating neurodegenerative disorders
BRPI0514303A (pt) * 2004-08-11 2008-06-10 Myriad Genetics Inc composição farmacêutica e método para tratar distúrbios neurodegenerativos
WO2006020852A2 (en) * 2004-08-11 2006-02-23 Myriad Genetics, Inc. Pharmaceutical composition and method for treating neurodegenerative disorders
WO2006050359A2 (en) * 2004-11-02 2006-05-11 Northwestern University Pyridazine compounds and methods
ES2615487T3 (es) * 2004-11-08 2017-06-07 Emcure Pharmaceuticals Limited un método eficaz para la preparación de (S)-3-[(1-dimetilamino)etil]-fenil-N-etil-N-metil-carbamato
US7619007B2 (en) 2004-11-23 2009-11-17 Adamas Pharmaceuticals, Inc. Method and composition for administering an NMDA receptor antagonist to a subject
KR20070084455A (ko) * 2004-11-23 2007-08-24 워너-램버트 캄파니 엘엘씨 지질혈증 치료용 ｈｍｇ ｃｏ-ａ 환원효소 억제제로서의7-(2ｈ-피라졸-3-일)-3,5-디히드록시-헵탄산 유도체
DE602006016934D1 (de) 2005-04-06 2010-10-28 Adamas Pharmaceuticals Inc Verfahren und zusammensetzungen zur behandlung von zns-erkrankungen
US20070015832A1 (en) * 2005-07-14 2007-01-18 Myriad Genetics, Incorporated Methods of treating overactive bladder and urinary incontinence
ES2267399B1 (es) 2005-08-04 2008-02-01 Ragactives, S.L. Procedimiento para la obtencion de carbamatos de fenilo.
EP1956904B1 (de) * 2005-12-09 2017-04-12 Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. Niedrig dosierter ladostigil zur behandlung von leichter kognitiver beeinträchtigung
TW200744576A (en) * 2006-02-24 2007-12-16 Teva Pharma Propargylated aminoindans, processes for preparation, and uses thereof
US7767843B2 (en) 2006-03-02 2010-08-03 Apotex Pharmachem Inc. Process for the preparation of phenylcarbamates
EP2015750A2 (de) * 2006-04-28 2009-01-21 Northwestern University Zusammensetzungen und behandlungen mit pyridazinverbindungen und cholisterinasehemmern
US20080033045A1 (en) * 2006-07-07 2008-02-07 Myriad Genetics, Incorporated Treatment of psychiatric disorders
CA2661009A1 (en) * 2006-08-17 2008-02-21 Alembic Limited Improved process for the preparation of rivastigmine
WO2008037433A1 (en) 2006-09-29 2008-04-03 Synthon B.V. Process for making aminoalkylphenyl carbamates and intermediates therefor
BRPI0718437A2 (pt) 2006-10-27 2013-11-19 Medivation Neurology Inc Métodos e terapias de combinação para tratar a doença de alzheimer usando, entre outros, dimebon e dolepezil
CA2677241A1 (en) 2007-02-02 2008-08-14 Colucid Pharmaceuticals, Inc. Compounds that inhibit cholinesterase
EP1980552A3 (de) 2007-04-10 2008-10-29 Dr. Reddy's Laboratories Ltd. Verfahren zur Herstellung von Rivastigmin oder einem Salz daraus
WO2008124969A1 (fr) * 2007-04-16 2008-10-23 Topharman Shanghai Co., Ltd. Méthode de préparation de rivastigmine et de ses intermédiaires
US7884121B2 (en) 2007-06-11 2011-02-08 Apotex Pharmachem Inc. Process for the preparation of phenylcarbamates
US20090048229A1 (en) * 2007-07-18 2009-02-19 Rupniak Nadia M J Methods for promoting wakefulness
US8593728B2 (en) * 2009-02-19 2013-11-26 Toyota Motor Engineering & Manufacturing North America, Inc. Multilayer photonic structures
EP2349976B1 (de) 2008-08-25 2012-12-26 Jubilant Life Sciences Limited Verfahren zur herstellung von (s)-3-[(1-dimethylamino)ethyl]phenyl-n-ethyl-n- methylcarbamat über neue zwischenprodukte
US8247405B2 (en) 2008-12-10 2012-08-21 Conopco, Inc. Skin lightening compositions with acetylcholinesterase inhibitors
CN101580482B (zh) * 2009-05-27 2014-04-23 沈阳药科大学 一种重酒石酸盐卡巴拉汀的制备方法和应用
ES2363395B1 (es) * 2010-01-20 2012-02-23 Farmalider, S.A. Composición farmacéutica l�?quida de rivastigmina o de una de sus sales de adición de �?cido para la administración por v�?a oral.
CN102134206B (zh) * 2010-01-27 2013-11-20 上海京新生物医药有限公司 一种卡巴拉汀的制备方法
EP2533645B1 (de) 2010-02-09 2016-07-27 The Johns Hopkins University Verfahren und zusammensetzungen zur verbesserung von kognitiven funktionen
WO2011151669A1 (en) 2010-06-02 2011-12-08 Jubilant Life Sciences Limited Process for producing enantiomerically enriched isomer of 3-(1-aminoethyl) phenyl derivative and employing the same to produce rivastigmine or its pharmaceutically acceptable salt
WO2011151359A1 (en) 2010-06-02 2011-12-08 Noscira, S.A. Combined treatment with a cholinesterase inhibitor and a thiadiazolidinedione derivative
DK2582799T3 (en) 2010-06-17 2018-02-12 Codexis Inc BIOCATALATORS AND PROCEDURES FOR THE SYNTHESIS OF (S) -3- (1-AMINOETHYL) -PHENOL
WO2012131699A1 (en) 2011-03-30 2012-10-04 Neon Laboratories Ltd. Process for preparation of highly pure 3-dimethylaminophenyl dimethylcarbamate
CN102786441B (zh) * 2011-05-18 2013-11-13 浙江海正药业股份有限公司 利凡斯的明的制备方法、其中间体以及中间体的制备方法
RU2014145682A (ru) 2012-04-14 2016-06-10 Интра-Селлулар Терапиз, Инк Органические соединения
ES2449215B1 (es) * 2012-09-17 2014-07-14 Galenicum Health S.L. Solución oral de (S)-3-[1-(dimetilamino)etil]fenil N-etil-N-metilcarbamato
JP6440625B2 (ja) 2012-11-14 2018-12-19 ザ・ジョンズ・ホプキンス・ユニバーシティー 精神分裂病を処置するための方法および組成物
EP2968220B1 (de) 2013-03-15 2021-05-05 Agenebio, Inc. Verfahren und zusammensetzungen zur verbesserung von kognitiven funktionen
US10806717B2 (en) 2013-03-15 2020-10-20 The Johns Hopkins University Methods and compositions for improving cognitive function
US10357486B2 (en) 2013-08-16 2019-07-23 Universiteit Maastricht Treatment of cognitive impairment with PDE4 inhibitor
US10925834B2 (en) 2015-05-22 2021-02-23 Agenebio, Inc. Extended release pharmaceutical compositions of levetiracetam
KR20200035359A (ko) 2018-09-26 2020-04-03 캐딜라 파마슈티클즈 리미티드 리바스티그민 제조용 중간체의 합성

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1905990A (en) * 1931-01-02 1933-04-25 Hoffmann La Roche Disubstituted carbamic acid esters of phenols containing a basic constituent
US2208485A (en) * 1937-04-24 1940-07-16 Hoffmann La Roche Process for the manufacture of disubstituted carbamic acid esters of phenols containing a basic substituent
US2362508A (en) * 1940-12-06 1944-11-14 Merck & Co Inc Therapeutic substances
US2493710A (en) * 1947-03-21 1950-01-03 Hoffmann La Roche Carbamic acid esters
DE1037753B (de) * 1956-07-13 1958-08-28 Rohm & Haas Schaedlingsbekaempfungsmittel

Also Published As

Publication number Publication date
EP0193926A3 (en) 1987-05-13
NL980031I1 (nl) 1999-01-04
US4948807A (en) 1990-08-14
EP0193926B1 (de) 1990-11-07
HU201297B (en) 1990-10-28
KR860007207A (ko) 1986-10-08
MY137602A (en) 2009-02-27
PL146301B1 (en) 1989-01-31
IE58838B1 (en) 1993-11-17
ZA861653B (en) 1987-10-28
GR860586B (en) 1986-07-07
ES8801193A1 (es) 1988-01-01
DK99186D0 (da) 1986-03-04
FI87197B (fi) 1992-08-31
LU90312I2 (fr) 1999-01-06
PT82127B (pt) 1988-07-01
AU595504B2 (en) 1990-04-05
NL980031I2 (nl) 1999-03-01
EP0193926B3 (de) 2010-04-28
CY2004004I1 (el) 2009-11-04
EP0193926A2 (de) 1986-09-10
HK130293A (en) 1993-12-03
JPH0255416B2 (de) 1990-11-27
IL74497A (en) 1990-02-09
PH23325A (en) 1989-07-14
KR940010764B1 (ko) 1994-11-11
DK99186A (da) 1986-09-06
ATE58130T1 (de) 1990-11-15
IE860558L (en) 1986-09-05
JPS61225158A (ja) 1986-10-06
FI860914A0 (fi) 1986-03-04
CA1284501C (en) 1991-05-28
IL74497A0 (en) 1985-06-30
FI87197C (fi) 1992-12-10
NZ215348A (en) 1990-04-26
AU5428486A (en) 1986-09-11
PT82127A (en) 1986-04-01
FI860914A (fi) 1986-09-06
HUT41718A (en) 1987-05-28
DE19875046I1 (de) 2003-09-04
CY1748A (en) 1994-06-03
ES552627A0 (es) 1988-01-01
CY2004004I2 (el) 2009-11-04
DK172851B1 (da) 1999-08-16

Similar Documents

Publication Publication Date Title
DE19875046I1 (de) Phenylcarbamate
FI872335A0 (fi) Bioreaktor.
DE3583779D1 (de) Gelzusammensetzungen von liposomen.
DE3681468D1 (de) Staubfreie koernige enzymzusammensetzung.
DE3583852D1 (de) Naehrstoffzusammensetzungen.
ATE38211T1 (de) Herstellung von zeolith-l.
DE3770889D1 (de) Herstellung von kubischem bornitrid.
DE3671902D1 (de) Haertbare zusammensetzung.
DE3581238D1 (de) Mikrobiologische herstellung von l-phenylalanin.
DE3670063D1 (de) Herstellung von thioantimonaten.
DE3650009T2 (de) Härtbare Zusammensetzung.
IT8720012A0 (it) Composizione anticorrosione.
DE3578163D1 (de) Herstellung von terpinen-4-olen.
DE3676116D1 (de) Herstellung von azetidin-derivaten.
SU1162191A1 (ru) 1,1-Этилиденди-(5-бром-2-фуроиламин), проявляющий противовоспалительную активность
KR880002128U (ko) 휴대용 사무구
ATE33492T1 (de) Herstellung von hoeheren arylestern.
ATE62471T1 (de) Herstellung von hydroxyaraldehyden.
ATE51604T1 (de) Herstellung von thioantimonaten.
ATE58368T1 (de) Herstellung von arylestern.
DE3762851D1 (de) Herstellung von spirobiindanbisphenolbischloroformiat-zusammensetzungen.
SU1489139A1 (ru) 3-Изобутил-1-(4-тиоцианатофенил)-5-фенил-Δ-пиразолин, проявляющий противовоспалительную активность
FI874288A (fi) Anordning foer upphoejning av taket pao ett lastutrymme i ett lastfordon.
ATE53598T1 (de) Haertbare zusammensetzung.

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
V448 Application of spc

Free format text: PRODUCT NAME: RIVASTIGMIN (EXELON); REGISTRATION NO/DATE: EU/1/98/066/001 - EU/1/98/066/012; 19980512

Spc suppl protection certif: 198 75 046

Filing date: 19981112

V457 Spc granted

Free format text: PRODUCT NAME: RIVASTIGMIN (EXELON); REGISTRATION NO/DATE: EU/1/98/066/001 - EU/1/98/066/012; 19980512

Spc suppl protection certif: 198 75 046

Filing date: 19981112

V464 Spc expired

Free format text: PRODUCT NAME: RIVASTIGMIN (EXELON); REGISTRATION NO/DATE: EU/1/98/066/001 - EU/1/98/066/012; 19980512

Spc suppl protection certif: 198 75 046

Filing date: 19981112

R071 Expiry of right

Free format text: PRODUCT NAME: RIVASTIGMIN (EXELON); NAT. REGISTRATION NO/DATE: EU/1/98/066/001-012 19980512; FIRST REGISTRATION: CH/LI 5427501-06 19970731

Spc suppl protection certif: 19875046

Filing date: 19981112

Expiry date: 20060305

Extension date: 20110304

Effective date: 20110305