DE3665303D1 - Process for the manufacture of cyclopropylamine - Google Patents

Process for the manufacture of cyclopropylamine

Info

Publication number
DE3665303D1
DE3665303D1 DE8686810240T DE3665303T DE3665303D1 DE 3665303 D1 DE3665303 D1 DE 3665303D1 DE 8686810240 T DE8686810240 T DE 8686810240T DE 3665303 T DE3665303 T DE 3665303T DE 3665303 D1 DE3665303 D1 DE 3665303D1
Authority
DE
Germany
Prior art keywords
cyclopropylamine
manufacture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8686810240T
Other languages
English (en)
Inventor
Joseph Thomas Blackwell
Harold Lenn Daughety
Henry Clanton Grace
Ward Hopkins Oliver
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Application granted granted Critical
Publication of DE3665303D1 publication Critical patent/DE3665303D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/08—Preparation of carboxylic acid esters by reacting carboxylic acids or symmetrical anhydrides with the hydroxy or O-metal group of organic compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00—Compounds containing amino groups bound to a carbon skeleton
    • C07C211/33—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C211/34—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of a saturated carbon skeleton
    • C07C211/35—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of a saturated carbon skeleton containing only non-condensed rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/09—Preparation of carboxylic acids or their salts, halides or anhydrides from carboxylic acid esters or lactones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
    • C07C67/317—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by splitting-off hydrogen or functional groups; by hydrogenolysis of functional groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/02—Systems containing only non-condensed rings with a three-membered ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE8686810240T 1985-06-10 1986-06-04 Process for the manufacture of cyclopropylamine Expired DE3665303D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/742,680 US4590292A (en) 1985-06-10 1985-06-10 Process for the manufacture of cyclopropylamine

Publications (1)

Publication Number Publication Date
DE3665303D1 true DE3665303D1 (en) 1989-10-05

Family

ID=24985801

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8686810240T Expired DE3665303D1 (en) 1985-06-10 1986-06-04 Process for the manufacture of cyclopropylamine

Country Status (6)

Country Link
US (1) US4590292A (de)
EP (1) EP0205403B1 (de)
JP (1) JPS61286351A (de)
KR (1) KR940007525B1 (de)
DE (1) DE3665303D1 (de)
ZA (1) ZA864281B (de)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3538133A1 (de) * 1985-10-26 1987-04-30 Huels Chemische Werke Ag Verfahren zur herstellung von reinen, chlorfreien cyclopropancarbonsaeureestern
DE3836782A1 (de) * 1988-10-28 1990-05-31 Bayer Ag Verfahren zur herstellung von cyclopropancarbonsaeureamid
DE3909142A1 (de) * 1989-03-21 1990-10-04 Basf Ag Verfahren zur herstellung von aminen
DE4025403A1 (de) * 1990-08-10 1992-02-13 Huels Chemische Werke Ag Verfahren zur herstellung von 2,2-dimethylcyclopropancarbonsaeurebutylestern und deren entsprechendem amid
DE4222497A1 (de) * 1992-07-09 1994-01-13 Huels Chemische Werke Ag Verfahren zur Herstellung von chlorfreiem Cyclopropancarbonsäuremethylester
DE4400328A1 (de) * 1994-01-07 1995-07-13 Huels Chemische Werke Ag Verfahren zur Herstellung von Cyclopropancarbonsäureamid
DE19523868A1 (de) * 1995-06-30 1997-01-02 Huels Chemische Werke Ag Verfahren zur Herstellung von Cyclopropanamin
CN1056600C (zh) * 1995-11-15 2000-09-20 中国石油化工总公司上海石油化工研究院 环丙羧酸酰胺的合成方法
DE19830633A1 (de) * 1998-07-09 2000-01-13 Degussa Verfahren zur Herstellung von Cyclopropylamin
US6392099B1 (en) 1998-11-19 2002-05-21 Eagleview Technologies, Inc. Method and apparatus for the preparation of ketones
US6369276B1 (en) 1998-11-19 2002-04-09 Eagleview Technologies, Inc. Catalyst structure for ketone production and method of making and using the same
US6552217B2 (en) * 2000-08-01 2003-04-22 Eastman Chemical Company Process for the preparation of alkyl 1-methylcyclopropanecarboxylate
US6545185B1 (en) 2001-03-29 2003-04-08 Eagleview Technologies, Inc. Preparation of ketones from aldehydes
DE10162684A1 (de) * 2001-12-19 2003-07-10 Bayer Ag Verfahren zur Herstellung von Aminen
US6683216B1 (en) 2002-11-06 2004-01-27 Eastman Chemical Company Continuous process for the preparation of amines
EP1966128A2 (de) * 2005-12-20 2008-09-10 Basf Se Verfahren zur herstellung von aminoalkansäureamiden
CN101024614B (zh) * 2006-02-23 2011-01-05 内蒙古师范大学 环丙胺生产酯化、环合工段的气相色谱中控分析方法
AU2011232759B2 (en) * 2006-08-05 2012-08-02 Astrazeneca Ab A process for the preparation of optically active cyclopropylamines
GB0615620D0 (en) * 2006-08-05 2006-09-13 Astrazeneca Ab A process for the preparation of optically active intermediates
GB0615619D0 (en) * 2006-08-05 2006-09-13 Astrazeneca Ab Chemical process for preparation of intermediates
CA2707101A1 (en) * 2007-11-29 2009-06-04 University Of Saskatchewan Process for the production of polyol base catalysts
CN108129330B (zh) * 2017-12-30 2021-06-25 浙江沙星科技有限公司 一种环丙胺连续化生产系统和生产方法
CN109265336B (zh) * 2018-09-26 2021-05-07 大丰跃龙化学有限公司 一种合成γ-氯代丁酸的方法
WO2023051768A1 (zh) * 2021-09-30 2023-04-06 利尔化学股份有限公司 (s)-4-氯-2-氨基丁酸盐酸盐及(s)-4-氯-2-氨基丁酸酯的制备方法
CN115093339A (zh) * 2022-07-20 2022-09-23 永农生物科学有限公司 一种l-草铵膦中间体的合成方法
CN115583967A (zh) * 2022-09-22 2023-01-10 佳木斯黑龙农药有限公司 一种精草铵膦的制备方法
CN117510328B (zh) * 2023-12-29 2024-04-12 山东京新药业有限公司 一种4-氯丁酸甲酯的制备方法

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3123629A (en) * 1964-03-03 Ch-chj-c-c-chs
US2449993A (en) * 1945-10-05 1948-09-28 Goodrich Co B F Preparation of beta-halo carboxylic acids
US2839576A (en) * 1955-11-23 1958-06-17 Union Carbide Corp Process for the production of epsilon-halocaproic acids
DE1080091B (de) * 1955-11-23 1960-04-21 Union Carbide Corp Verfahren zur Herstellung von ªŠ-Halogencapronsaeuren
FR1269127A (fr) * 1960-06-20 1961-08-11 Rhone Poulenc Sa Procédé de préparation de l'acide chrysanthémique
US3010971A (en) * 1960-08-04 1961-11-28 Smith Kline French Lab Cyclopropylamine derivatives and processes for their preparation
US3294833A (en) * 1963-05-08 1966-12-27 Gulf Oil Corp Manufacturing esters of 1-alkoxycyclopropanecarboxylic acids
US3417114A (en) * 1965-07-20 1968-12-17 C P Hall Company Of Illinois Method of making amides from moisture and acid-gas containing esters
GB1164534A (en) * 1967-02-21 1969-09-17 Ici Ltd Production of Di-N-Methylamides
ES370147A1 (es) * 1968-08-29 1971-04-01 Gulf Research Development Co Un procedimiento para fabricar ciclopropilamina.
US3711549A (en) * 1970-05-19 1973-01-16 Gulf Research Development Co Process for manufacturing cyclopropylamine
JPS51104A (en) * 1974-06-19 1976-01-05 Takuma Uchida Aasudoriruniokeru doriringubaketsutosokobutakaihohoho
DE2710174A1 (de) * 1977-03-09 1978-09-14 Bayer Ag Verfahren zur herstellung von dihalogenvinyl-cyclopropancarbonsaeuren und deren ester
DE2941211C2 (de) * 1979-10-11 1982-11-25 Degussa Ag, 6000 Frankfurt Verfahren zum gegebenenfalls kontinuierlichen Cyclisieren von γ-Chlorcarbonsäureestern
DE3026094C2 (de) * 1980-07-10 1983-01-05 Degussa Ag, 6000 Frankfurt Verfahren zur Herstellung von Cyclopropancarbonsäureamiden
JPS59141538A (ja) * 1983-02-01 1984-08-14 Agency Of Ind Science & Technol ハロゲン化プロピオン酸エステルの製法

Also Published As

Publication number Publication date
EP0205403B1 (de) 1989-08-30
JPH0529214B2 (de) 1993-04-28
US4590292A (en) 1986-05-20
JPS61286351A (ja) 1986-12-16
KR870000281A (ko) 1987-02-17
KR940007525B1 (ko) 1994-08-19
EP0205403A1 (de) 1986-12-17
ZA864281B (en) 1987-02-25

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: NOVARTIS AG, BASEL, CH