DE3588078D1 - Heterologes System zum Nachweis markierter DNA - Google Patents
Heterologes System zum Nachweis markierter DNAInfo
- Publication number
- DE3588078D1 DE3588078D1 DE3588078T DE3588078T DE3588078D1 DE 3588078 D1 DE3588078 D1 DE 3588078D1 DE 3588078 T DE3588078 T DE 3588078T DE 3588078 T DE3588078 T DE 3588078T DE 3588078 D1 DE3588078 D1 DE 3588078D1
- Authority
- DE
- Germany
- Prior art keywords
- biotinylated
- lectin
- dna
- streptavidin
- enzyme complex
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
- G01N33/532—Production of labelled immunochemicals
- G01N33/535—Production of labelled immunochemicals with enzyme label or co-enzymes, co-factors, enzyme inhibitors or enzyme substrates
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/803—Physical recovery methods, e.g. chromatography, grinding
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/81—Packaged device or kit
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/807—Apparatus included in process claim, e.g. physical support structures
- Y10S436/808—Automated or kit
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/824—Immunological separation techniques
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/827—Lectins
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US57873284A | 1984-02-09 | 1984-02-09 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE3588078D1 true DE3588078D1 (de) | 1996-02-29 |
DE3588078T2 DE3588078T2 (de) | 1996-09-19 |
Family
ID=24314075
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE3588078T Expired - Lifetime DE3588078T2 (de) | 1984-02-09 | 1985-02-08 | Heterologes System zum Nachweis markierter DNA |
Country Status (11)
Country | Link |
---|---|
US (1) | US4889798A (de) |
EP (1) | EP0151492B1 (de) |
JP (1) | JPS60188095A (de) |
AT (1) | ATE133261T1 (de) |
AU (1) | AU3844485A (de) |
CA (1) | CA1314810C (de) |
DE (1) | DE3588078T2 (de) |
DK (1) | DK61085A (de) |
ES (2) | ES8802188A1 (de) |
IL (1) | IL74262A0 (de) |
NO (1) | NO850493L (de) |
Families Citing this family (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4957858A (en) * | 1986-04-16 | 1990-09-18 | The Salk Instute For Biological Studies | Replicative RNA reporter systems |
ATE107031T1 (de) * | 1984-12-03 | 1994-06-15 | Hoechst Celanese Corp | Verfahren zur bestimmung eines liganden. |
ES8707343A1 (es) * | 1985-06-13 | 1987-07-16 | Amgen | Un metodo para aislar una secuencia de acido nucleico objetivo seleccionada |
US5273882A (en) * | 1985-06-13 | 1993-12-28 | Amgen | Method and kit for performing nucleic acid hybridization assays |
US4724203A (en) * | 1985-10-04 | 1988-02-09 | Miles Laboratories, Inc. | Caproylamidobiotinylated peroxidase |
US5817797A (en) * | 1988-06-01 | 1998-10-06 | The United States Of America As Represented By The Department Of Health And Human Services | Sequencing DNA; a modification of the polymerase chain reaction |
CA2002076A1 (en) * | 1988-11-21 | 1990-05-21 | Brent A. Burdick | Diagnostic kit and method using a solid phase capture means for detecting nucleic acids |
GB2239948B (en) * | 1989-12-28 | 1994-01-12 | Aisin Seiki | Fluorescence assay using phosphatase and a naphthol phosphate derivative |
JP2646814B2 (ja) * | 1990-08-07 | 1997-08-27 | アイシン精機株式会社 | 核酸等の検定方法 |
US5264343A (en) * | 1990-08-31 | 1993-11-23 | Eleanor Roosevelt Institute | Method for distinguishing normal and cancer cells |
EP0648281A4 (de) * | 1991-09-10 | 1997-06-04 | Jack D Love | Zielgerichte amplifikation von dna und rna und signalamplifikation. |
US5329461A (en) * | 1992-07-23 | 1994-07-12 | Acrogen, Inc. | Digital analyte detection system |
JPH07165800A (ja) * | 1993-12-08 | 1995-06-27 | Res Dev Corp Of Japan | 人工蛋白質超分子とその製造法 |
US5731153A (en) * | 1996-08-26 | 1998-03-24 | The Regents Of The University Of California | Identification of random nucleic acid sequence aberrations using dual capture probes which hybridize to different chromosome regions |
US5783387A (en) * | 1995-02-06 | 1998-07-21 | The Regents Of The University Of California | Method for identifying and quantifying nucleic acid sequence aberrations |
US6096508A (en) * | 1995-08-16 | 2000-08-01 | Kirkegaard & Perry Laboratoies, Inc. | Method of reducing background in biotin-based assays |
DE19724787A1 (de) * | 1997-06-06 | 1998-12-10 | Biotez Berlin Buch Gmbh Bioche | Streptavidin/Avidin beschichtete Oberflächen |
CA2313483C (en) * | 1997-12-12 | 2017-12-05 | Digene Corporation | Assessment of human papilloma virus-related disease |
KR20000074881A (ko) * | 1999-05-26 | 2000-12-15 | 황승용 | 마이크로웰을 이용한 디엔에이 돌연변이의 확인방법 및 키트 |
JP3781934B2 (ja) * | 1999-12-22 | 2006-06-07 | 株式会社ニチレイバイオサイエンス | 酵素−タンパク質複合体 |
US6686461B1 (en) | 2000-03-22 | 2004-02-03 | Solulink Bioscience, Inc. | Triphosphate oligonucleotide modification reagents and uses thereof |
US7102024B1 (en) | 2000-08-01 | 2006-09-05 | Schwartz David A | Functional biopolymer modification reagents and uses thereof |
US7439016B1 (en) | 2000-06-15 | 2008-10-21 | Digene Corporation | Detection of nucleic acids by type-specific hybrid capture method |
US7601497B2 (en) | 2000-06-15 | 2009-10-13 | Qiagen Gaithersburg, Inc. | Detection of nucleic acids by target-specific hybrid capture method |
CA2705984A1 (en) | 2007-11-28 | 2009-06-04 | Great Basin Scientific | Methods and compositions for amplifying a detectable signal |
US8383337B2 (en) * | 2008-07-18 | 2013-02-26 | General Electric Company | Methods using metal oxide particles for analyte detection |
US9115386B2 (en) | 2008-09-26 | 2015-08-25 | Children's Medical Center Corporation | Selective oxidation of 5-methylcytosine by TET-family proteins |
US8288520B2 (en) | 2008-10-27 | 2012-10-16 | Qiagen Gaithersburg, Inc. | Fast results hybrid capture assay and system |
AU2010208311B2 (en) * | 2009-01-28 | 2016-07-07 | Qiagen Gaithersburg, Inc. | Sequence-specific large volume sample preparation method and assay |
EP2425019B1 (de) | 2009-05-01 | 2014-03-19 | QIAGEN Gaithersburg, Inc. | Ungezieltes verstärkungsverfahren zur erkennung von rna-spleissformen in einer probe |
CA2773320C (en) | 2009-09-14 | 2018-02-20 | Qiagen Gaithersburg, Inc. | Compositions and methods for recovery of nucleic acids or proteins from tissue samples fixed in cytology media |
EP2528932B1 (de) * | 2010-01-29 | 2016-11-30 | QIAGEN Gaithersburg, Inc. | Verfahren und zusammensetzungen für sequenzspezifische reinigung und multiplex-analyse von nukleinsäuren |
CN102822353A (zh) | 2010-01-29 | 2012-12-12 | 奇亚根盖瑟斯堡股份有限公司 | 确定和确认样品中存在hpv的方法 |
WO2011146629A2 (en) | 2010-05-19 | 2011-11-24 | Qiagen Gaithersburg Inc. | Methods and compositions for sequence-specific purification and multiplex analysis of nucleic acids |
EP2678442B1 (de) | 2011-02-24 | 2019-01-16 | QIAGEN Gaithersburg, Inc. | Materialien und verfahren für den nachweis von hpv-nukleinsäuren |
CA3153763A1 (en) | 2013-03-11 | 2014-10-09 | Meso Scale Technologies, Llc. | Improved methods for conducting multiplexed assays |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2422956A1 (fr) * | 1978-04-13 | 1979-11-09 | Pasteur Institut | Procede de detection et de caracterisation d'un acide nucleique ou d'une sequence de celui-ci, et reactif enzymatique pour la mise en oeuvre de ce procede |
JPS5510590A (en) * | 1978-05-04 | 1980-01-25 | Wellcome Found | Enzyme immunity quantity analysis |
US4334017A (en) * | 1979-04-16 | 1982-06-08 | Massachusetts Institute Of Technology | Method for detecting cancer in mammalian tissue |
US4478914B1 (en) * | 1980-01-24 | 1997-06-17 | Roger W Giese | Process for applying multiple layers of a protein and a ligand extender to a surface and to the multiple layer system |
CA1219824A (en) * | 1981-04-17 | 1987-03-31 | David C. Ward | Modified nucleotides and methods of preparing and using same |
US4395486A (en) * | 1981-08-19 | 1983-07-26 | Medical College Of Ga. Research Inst., Inc. | Method for the direct analysis of sickle cell anemia |
GB2114287B (en) * | 1982-01-29 | 1985-10-30 | Otsuka Pharma Co Ltd | Process for determining tumor-associated glycolinkage |
CA1254525A (en) * | 1983-04-13 | 1989-05-23 | Christine L. Brakel | Kit for terminally chemically labeling dna |
DK188184A (da) * | 1983-04-20 | 1984-10-21 | Enzo Biochem Inc | Fremgangsmaade til dannelse af et kompleks af biologisk aktive eller funktionelle forbindelser og anvendelse af forbindelserne |
CA1228811A (en) * | 1983-05-05 | 1987-11-03 | Robert G. Pergolizzi | Assay method utilizing polynucleotide sequences |
US4687732A (en) * | 1983-06-10 | 1987-08-18 | Yale University | Visualization polymers and their application to diagnostic medicine |
US4550075A (en) * | 1983-06-22 | 1985-10-29 | Kallestad Laboratories, Inc. | Method for ligand determination utilizing an immunoassay monitorable by biotin-containing enzymes, and compositions therefor |
JPS61501047A (ja) * | 1984-01-27 | 1986-05-22 | モレキュラ−・バイオシステムズ,インコ−ポレイテッド | 固定化したリポ−タ−グル−プ類の測定方法 |
-
1985
- 1985-02-05 AU AU38444/85A patent/AU3844485A/en not_active Abandoned
- 1985-02-06 IL IL74262A patent/IL74262A0/xx unknown
- 1985-02-07 JP JP60020996A patent/JPS60188095A/ja active Pending
- 1985-02-07 CA CA000473830A patent/CA1314810C/en not_active Expired - Lifetime
- 1985-02-08 DK DK61085A patent/DK61085A/da not_active Application Discontinuation
- 1985-02-08 EP EP85101353A patent/EP0151492B1/de not_active Expired - Lifetime
- 1985-02-08 AT AT85101353T patent/ATE133261T1/de not_active IP Right Cessation
- 1985-02-08 ES ES540250A patent/ES8802188A1/es not_active Expired
- 1985-02-08 NO NO850493A patent/NO850493L/no unknown
- 1985-02-08 DE DE3588078T patent/DE3588078T2/de not_active Expired - Lifetime
-
1986
- 1986-04-16 ES ES554045A patent/ES8800439A1/es not_active Expired
-
1987
- 1987-02-13 US US07/015,563 patent/US4889798A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
ES554045A0 (es) | 1987-10-16 |
NO850493L (no) | 1985-08-12 |
EP0151492A2 (de) | 1985-08-14 |
ES8802188A1 (es) | 1988-04-01 |
IL74262A0 (en) | 1985-05-31 |
EP0151492B1 (de) | 1996-01-17 |
ES8800439A1 (es) | 1987-10-16 |
AU3844485A (en) | 1985-08-15 |
EP0151492A3 (en) | 1988-11-09 |
DE3588078T2 (de) | 1996-09-19 |
ES540250A0 (es) | 1988-04-01 |
DK61085A (da) | 1985-08-10 |
JPS60188095A (ja) | 1985-09-25 |
CA1314810C (en) | 1993-03-23 |
ATE133261T1 (de) | 1996-02-15 |
DK61085D0 (da) | 1985-02-08 |
US4889798A (en) | 1989-12-26 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |