DE3587558D1 - Rekombinante DNS-Vektoren fähig zur Apoaequorinexpression, Apoaequorinpeptide und deren Herstellung und diese Vektoren enthaltende Mikroorganismen. - Google Patents
Rekombinante DNS-Vektoren fähig zur Apoaequorinexpression, Apoaequorinpeptide und deren Herstellung und diese Vektoren enthaltende Mikroorganismen.Info
- Publication number
- DE3587558D1 DE3587558D1 DE85309419T DE3587558T DE3587558D1 DE 3587558 D1 DE3587558 D1 DE 3587558D1 DE 85309419 T DE85309419 T DE 85309419T DE 3587558 T DE3587558 T DE 3587558T DE 3587558 D1 DE3587558 D1 DE 3587558D1
- Authority
- DE
- Germany
- Prior art keywords
- apoaequorin
- extracts
- paeq1
- vectors
- peptides
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
- C07K14/43595—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from coelenteratae, e.g. medusae
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US68790384A | 1984-12-31 | 1984-12-31 | |
US70230885A | 1985-02-15 | 1985-02-15 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE3587558D1 true DE3587558D1 (de) | 1993-10-07 |
DE3587558T2 DE3587558T2 (de) | 1994-03-31 |
Family
ID=27104107
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE3588168T Expired - Lifetime DE3588168T2 (de) | 1984-12-31 | 1985-12-23 | Apoaequorin Peptide, rekombinante DNS-Vektoren fähig zu deren Expression und diese Vektoren enthaltende Mikroorganismen |
DE85309419T Expired - Lifetime DE3587558T2 (de) | 1984-12-31 | 1985-12-23 | Rekombinante DNS-Vektoren fähig zur Apoaequorinexpression, Apoaequorinpeptide und deren Herstellung und diese Vektoren enthaltende Mikroorganismen. |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE3588168T Expired - Lifetime DE3588168T2 (de) | 1984-12-31 | 1985-12-23 | Apoaequorin Peptide, rekombinante DNS-Vektoren fähig zu deren Expression und diese Vektoren enthaltende Mikroorganismen |
Country Status (12)
Country | Link |
---|---|
US (1) | US5162227A (de) |
EP (2) | EP0187519B1 (de) |
JP (2) | JP2894687B2 (de) |
CN (1) | CN1010414B (de) |
AT (2) | ATE93867T1 (de) |
CA (1) | CA1274481A (de) |
DE (2) | DE3588168T2 (de) |
DK (1) | DK604385A (de) |
ES (1) | ES8705467A1 (de) |
FI (1) | FI855141A (de) |
NO (1) | NO855223L (de) |
NZ (1) | NZ214563A (de) |
Families Citing this family (38)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5422266A (en) * | 1984-12-31 | 1995-06-06 | University Of Georgia Research Foundation, Inc. | Recombinant DNA vectors capable of expressing apoaequorin |
JPS62171695A (ja) * | 1985-12-14 | 1987-07-28 | Chisso Corp | 発光蛋白アクアリン遺伝子を用いるアクアリン活性を有する蛋白質の製造法 |
JPS62261942A (ja) * | 1986-05-08 | 1987-11-14 | Chisso Corp | 金属の検出方法 |
US5093240A (en) * | 1986-10-15 | 1992-03-03 | Chisso Corporation | Variant aequorin genes and process for producing variant aequorin proteins |
JPS63102695A (ja) * | 1986-10-20 | 1988-05-07 | Chisso Corp | 大腸菌の菌体外分泌ベクタ−を用いる発光蛋白エクオリンの製造法 |
JPS6439990A (en) * | 1987-08-05 | 1989-02-10 | Chisso Corp | Fused gene by bonding aequorin gene to functional gene |
JPS6447379A (en) * | 1987-08-19 | 1989-02-21 | Chisso Corp | Preparation of calcium-dependent oxygenation enzyme |
JP2592623B2 (ja) * | 1987-11-18 | 1997-03-19 | チッソ株式会社 | アポエクオリンの製造法 |
AU3342689A (en) * | 1988-03-24 | 1989-10-16 | Igen Incorporated | Luminescent chimeric proteins |
JPH01285196A (ja) * | 1988-05-11 | 1989-11-16 | Chisso Corp | 発光蛋白エクオリンの製造法 |
US5292658A (en) * | 1989-12-29 | 1994-03-08 | University Of Georgia Research Foundation, Inc. Boyd Graduate Studies Research Center | Cloning and expressions of Renilla luciferase |
US5360728A (en) * | 1992-12-01 | 1994-11-01 | Woods Hole Oceanographic Institution (W.H.O.I.) | Modified apoaequorin having increased bioluminescent activity |
AU694745B2 (en) * | 1993-09-10 | 1998-07-30 | Trustees Of Columbia University In The City Of New York, The | Uses of green fluorescent protein |
WO1995021191A1 (en) * | 1994-02-04 | 1995-08-10 | William Ward | Bioluminescent indicator based upon the expression of a gene for a modified green-fluorescent protein |
US6329139B1 (en) | 1995-04-25 | 2001-12-11 | Discovery Partners International | Automated sorting system for matrices with memory |
US5804387A (en) * | 1996-02-01 | 1998-09-08 | The Board Of Trustees Of The Leland Stanford Junior University | FACS-optimized mutants of the green fluorescent protein (GFP) |
US5876995A (en) | 1996-02-06 | 1999-03-02 | Bryan; Bruce | Bioluminescent novelty items |
US6247995B1 (en) | 1996-02-06 | 2001-06-19 | Bruce Bryan | Bioluminescent novelty items |
AR006928A1 (es) | 1996-05-01 | 1999-09-29 | Pioneer Hi Bred Int | Una molecula de adn aislada que codifica una proteina fluorescente verde como marcador rastreable para la transformacion de plantas, un metodo para laproduccion de plantas transgenicas, un vector de expresion, una planta transgenica y celulas de dichas plantas. |
US6416960B1 (en) | 1996-08-08 | 2002-07-09 | Prolume, Ltd. | Detection and visualization of neoplastic tissues and other tissues |
WO1998026277A2 (en) | 1996-12-12 | 1998-06-18 | Prolume, Ltd. | Apparatus and method for detecting and identifying infectious agents |
US5876935A (en) * | 1997-01-08 | 1999-03-02 | Dade Behring Inc. | Luminescent specific binding assay |
US6090919A (en) * | 1997-01-31 | 2000-07-18 | The Board Of Trustees Of The Leland Stanford Junior University | FACS-optimized mutants of the green fluorescent protein (GFP) |
CA2285676C (en) | 1997-04-04 | 2011-03-08 | Donald P. Weeks | Methods and materials for making and using transgenic dicamba-degrading organisms |
US6284496B1 (en) | 1997-10-03 | 2001-09-04 | University Of South Florida | DNA vector for determining the presence of out-of-reading-frame mutations |
US6248542B1 (en) * | 1997-12-09 | 2001-06-19 | Massachusetts Institute Of Technology | Optoelectronic sensor |
EP1925320A3 (de) | 1998-03-27 | 2008-09-03 | Prolume, Ltd. | Luciferasen, fluoreszierende Proteine, Nukleinsäuren zur Kodierung der Luciferasen und der fluoreszierenden Proteine sowie deren Verwendung zur Diagnose, zum Screening mit hohem Durchsatz und zur Behandlung neuartiger Probleme |
EP1064360B1 (de) | 1998-03-27 | 2008-03-05 | Prolume, Ltd. | Luciferase, gfp fluoreszenzproteine, kodierende nukleinsaüre und ihre verwendung in der diagnose |
EP1031630B1 (de) * | 1999-02-22 | 2004-10-20 | Matsushita Electric Industrial Co., Ltd. | Verfahren zum Nachweis von Bakterien |
US7109315B2 (en) | 2000-03-15 | 2006-09-19 | Bruce J. Bryan | Renilla reniformis fluorescent proteins, nucleic acids encoding the fluorescent proteins and the use thereof in diagnostics, high throughput screening and novelty items |
US7422860B2 (en) | 2001-02-07 | 2008-09-09 | Massachusetts Institute Of Technology | Optoelectronic detection system |
US8216797B2 (en) | 2001-02-07 | 2012-07-10 | Massachusetts Institute Of Technology | Pathogen detection biosensor |
CN101551337B (zh) * | 2001-02-07 | 2013-06-19 | 麻省理工学院 | 光电子探测系统 |
FR2836475B1 (fr) | 2002-02-26 | 2007-02-23 | Aventis Pharma Sa | Procede de detection de ligands du recepteur de la leptine |
US7663022B1 (en) | 2002-07-15 | 2010-02-16 | Bruce Eric Hudkins | Transgenic bioluminescent plants |
US7345160B2 (en) | 2004-03-29 | 2008-03-18 | University Of Kentucky Research Foundation | Aequorin and obelin mutants with differing wavelengths and bioluminescence |
CN102666574A (zh) * | 2009-07-14 | 2012-09-12 | Emd密理博公司 | 具有增加的钙亲和性及增强的生物发光的修饰的发光蛋白及其应用 |
MA40959A (fr) * | 2014-11-11 | 2017-09-19 | Quincy Bioscience Llc | Compositions contenant de l'apoaéquorine et leurs procédés d'utilisation pour traiter l'inflammation neuronale |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4604364A (en) * | 1974-01-04 | 1986-08-05 | Kosak Kenneth M | Bioluminescent tracer composition and method of use in immunoassays |
US4396579A (en) * | 1981-08-06 | 1983-08-02 | Miles Laboratories, Inc. | Luminescence detection device |
JPS61135586A (ja) * | 1984-08-24 | 1986-06-23 | Chisso Corp | 発光蛋白アクアリン遺伝子を有するプラスミドおよび該発光蛋白の生合成法 |
JPS62171695A (ja) * | 1985-12-14 | 1987-07-28 | Chisso Corp | 発光蛋白アクアリン遺伝子を用いるアクアリン活性を有する蛋白質の製造法 |
-
1985
- 1985-12-16 NZ NZ214563A patent/NZ214563A/en unknown
- 1985-12-20 NO NO855223A patent/NO855223L/no unknown
- 1985-12-23 FI FI855141A patent/FI855141A/fi not_active Application Discontinuation
- 1985-12-23 DE DE3588168T patent/DE3588168T2/de not_active Expired - Lifetime
- 1985-12-23 EP EP85309419A patent/EP0187519B1/de not_active Expired - Lifetime
- 1985-12-23 DK DK604385A patent/DK604385A/da not_active Application Discontinuation
- 1985-12-23 AT AT85309419T patent/ATE93867T1/de not_active IP Right Cessation
- 1985-12-23 DE DE85309419T patent/DE3587558T2/de not_active Expired - Lifetime
- 1985-12-23 AT AT92121372T patent/ATE159291T1/de not_active IP Right Cessation
- 1985-12-23 EP EP92121372A patent/EP0540064B1/de not_active Expired - Lifetime
- 1985-12-26 JP JP60299601A patent/JP2894687B2/ja not_active Expired - Lifetime
- 1985-12-30 CA CA000498763A patent/CA1274481A/en not_active Expired - Lifetime
- 1985-12-30 ES ES550528A patent/ES8705467A1/es not_active Expired
- 1985-12-30 CN CN85109740A patent/CN1010414B/zh not_active Expired
-
1988
- 1988-03-17 US US07/173,045 patent/US5162227A/en not_active Expired - Lifetime
-
1992
- 1992-12-25 JP JP4347199A patent/JP2655981B2/ja not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
AU5142085A (en) | 1986-07-10 |
CA1274481A (en) | 1990-09-25 |
DE3588168T2 (de) | 1998-04-23 |
NZ214563A (en) | 1991-05-28 |
EP0187519A3 (en) | 1988-01-27 |
EP0187519B1 (de) | 1993-09-01 |
DE3588168D1 (de) | 1997-11-20 |
NO855223L (no) | 1986-07-01 |
US5162227A (en) | 1992-11-10 |
FI855141A0 (fi) | 1985-12-23 |
ATE93867T1 (de) | 1993-09-15 |
FI855141A (fi) | 1986-07-01 |
JPH06217779A (ja) | 1994-08-09 |
DK604385A (da) | 1986-07-01 |
EP0540064B1 (de) | 1997-10-15 |
CN1010414B (zh) | 1990-11-14 |
ES550528A0 (es) | 1987-05-01 |
JP2655981B2 (ja) | 1997-09-24 |
DE3587558T2 (de) | 1994-03-31 |
JP2894687B2 (ja) | 1999-05-24 |
ES8705467A1 (es) | 1987-05-01 |
AU589930B2 (en) | 1989-10-26 |
DK604385D0 (da) | 1985-12-23 |
JPS61224989A (ja) | 1986-10-06 |
EP0540064A1 (de) | 1993-05-05 |
CN85109740A (zh) | 1987-02-04 |
EP0187519A2 (de) | 1986-07-16 |
ATE159291T1 (de) | 1997-11-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |