DE3586380D1 - Verfahren zur messung von strahlungsschwankungen und anwendung desselben zum nachweis eines analyten. - Google Patents

Verfahren zur messung von strahlungsschwankungen und anwendung desselben zum nachweis eines analyten.

Info

Publication number
DE3586380D1
DE3586380D1 DE8585306450T DE3586380T DE3586380D1 DE 3586380 D1 DE3586380 D1 DE 3586380D1 DE 8585306450 T DE8585306450 T DE 8585306450T DE 3586380 T DE3586380 T DE 3586380T DE 3586380 D1 DE3586380 D1 DE 3586380D1
Authority
DE
Germany
Prior art keywords
duration
fluctuations
analyt
detect
same
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8585306450T
Other languages
English (en)
Other versions
DE3586380T2 (de
Inventor
Jonathan Briggs
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Syntex USA LLC
Original Assignee
Syntex USA LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex USA LLC filed Critical Syntex USA LLC
Publication of DE3586380D1 publication Critical patent/DE3586380D1/de
Application granted granted Critical
Publication of DE3586380T2 publication Critical patent/DE3586380T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measurement Of Radiation (AREA)
  • Investigating Or Analyzing Materials Using Thermal Means (AREA)
DE8585306450T 1984-09-12 1985-09-11 Verfahren zur messung von strahlungsschwankungen und anwendung desselben zum nachweis eines analyten. Expired - Fee Related DE3586380T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/650,320 US4676640A (en) 1984-09-12 1984-09-12 Fluctuation analysis for enhanced particle detection

Publications (2)

Publication Number Publication Date
DE3586380D1 true DE3586380D1 (de) 1992-08-27
DE3586380T2 DE3586380T2 (de) 1993-03-11

Family

ID=24608399

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8585306450T Expired - Fee Related DE3586380T2 (de) 1984-09-12 1985-09-11 Verfahren zur messung von strahlungsschwankungen und anwendung desselben zum nachweis eines analyten.

Country Status (7)

Country Link
US (1) US4676640A (de)
EP (1) EP0175545B1 (de)
JP (1) JPS6183938A (de)
AT (1) ATE78586T1 (de)
AU (1) AU584351B2 (de)
CA (1) CA1277505C (de)
DE (1) DE3586380T2 (de)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4739171A (en) * 1982-07-12 1988-04-19 Syntex (U.S.A.) Inc. Limited volume method and apparatus for particle counting
US5040889A (en) * 1986-05-30 1991-08-20 Pacific Scientific Company Spectrometer with combined visible and ultraviolet sample illumination
US4934811A (en) * 1988-04-01 1990-06-19 Syntex (U.S.A.) Inc. Apparatus and method for detection of fluorescence or light scatter
US5013150A (en) * 1988-04-01 1991-05-07 Syntex (U.S.A.) Inc. Method for detection of fluorescence or light scatter
US5026159A (en) * 1989-05-19 1991-06-25 Acrogen, Inc. Area-modulated luminescence (AML)
US5304492A (en) * 1991-11-26 1994-04-19 The State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon State University Spectrophotometer for chemical analyses of fluids
DE4429239A1 (de) * 1994-08-18 1996-02-22 Basf Ag Verfahren zur Fluoreszenz-Korrelations-Spektroskopie und Vorrichtung zu dessen Durchführung
FI98765C (fi) * 1995-01-16 1997-08-11 Erkki Soini Virtaussytometrinen menetelmä ja laite
US5981180A (en) * 1995-10-11 1999-11-09 Luminex Corporation Multiplexed analysis of clinical specimens apparatus and methods
WO1997014028A2 (en) 1995-10-11 1997-04-17 Luminex Corporation Multiplexed analysis of clinical specimens apparatus and method
US5736330A (en) * 1995-10-11 1998-04-07 Luminex Corporation Method and compositions for flow cytometric determination of DNA sequences
AT404513B (de) * 1996-07-12 1998-12-28 Avl Verbrennungskraft Messtech Verfahren und messanordnung zur optischen bestimmung der totalen hämoglobinkonzentration
US6449562B1 (en) 1996-10-10 2002-09-10 Luminex Corporation Multiplexed analysis of clinical specimens apparatus and method
JP3447562B2 (ja) * 1998-05-21 2003-09-16 浜松ホトニクス株式会社 解析方法および解析装置
DE10013377A1 (de) * 2000-03-17 2001-09-20 Dade Behring Marburg Gmbh Induzierte Aggregation und Agglutination von Plättchen
US6813569B2 (en) 2000-04-13 2004-11-02 Ecole Polytechnique Federale De Lausanne (Epfl) Assembly and method for a correlator structure
US6534768B1 (en) 2000-10-30 2003-03-18 Euro-Oeltique, S.A. Hemispherical detector
ATE418084T1 (de) * 2004-02-09 2009-01-15 Koninkl Philips Electronics Nv Fluoreszenz-mikroskop-anordnung
US7232687B2 (en) * 2004-04-07 2007-06-19 Beckman Coulter, Inc. Multiple sorter monitor and control subsystem for flow cytometer
US8574461B2 (en) 2006-11-03 2013-11-05 Tufts University Electroactive biopolymer optical and electro-optical devices and method of manufacturing the same
WO2008127402A2 (en) 2006-11-03 2008-10-23 Trustees Of Tufts College Biopolymer sensor and method of manufacturing the same
WO2008127404A2 (en) 2006-11-03 2008-10-23 Trustees Of Tufts College Nanopatterned biopolymer optical device and method of manufacturing the same
US20100046902A1 (en) 2006-11-03 2010-02-25 Trustees Of Tufts College Biopolymer photonic crystals and method of manufacturing the same
US9599891B2 (en) 2007-11-05 2017-03-21 Trustees Of Tufts College Fabrication of silk fibroin photonic structures by nanocontact imprinting
JP2011525254A (ja) * 2008-06-18 2011-09-15 トラスティーズ オブ タフツ カレッジ 食用のホログラフィック絹製品
WO2010088585A1 (en) * 2009-01-30 2010-08-05 Trustees Of Boston University Chemical/biological sensor employing scattered chromatic components in nano-patterned aperiodic surfaces
AU2010242010B2 (en) 2009-02-12 2015-06-18 Trustees Of Tufts College Nanoimprinting of silk fibroin structures for biomedical and biophotonic applications
US20120050734A1 (en) * 2009-04-15 2012-03-01 Stefan Wennmalm Inverse-fluorescence correlation spectroscopy
EP2457087A4 (de) 2009-07-20 2015-09-02 Tufts University Trustees Of Tufts College Komplett aus proteinen bestehende implantierbare und abbaubare reflektoren
EP2474054A4 (de) 2009-08-31 2013-03-13 Tufts University Trustees Of Tufts College Seidentransistorvorrichtungen
JP5442052B2 (ja) * 2012-02-16 2014-03-12 株式会社堀場製作所 粒子分析装置

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US99266A (en) * 1870-01-25 Improvement in liquid-meters
US3941479A (en) * 1974-09-26 1976-03-02 G. D. Searle & Co. Use of modulated stimulus to improve detection sensitivity for signals from particles in a flow chamber
US4178917A (en) * 1979-01-03 1979-12-18 Shapiro Howard M Method and system for non-invasive detection of zinc protoporphyrin in erythrocytes
US4407964A (en) * 1980-10-07 1983-10-04 The Regents Of The University Of California Homogeneous fluoroimmunoassay involving sensing radiation for forward and back directions
US4421860A (en) * 1980-10-07 1983-12-20 The Regents Of The University Of California Homogeneous fluoroimmunoassay involving autocorrelation processing of optically sensed signals
US4564598A (en) * 1982-07-12 1986-01-14 Syntex (U.S.A.) Inc. Limited volume method for particle counting
US4537861A (en) * 1983-02-03 1985-08-27 Elings Virgil B Apparatus and method for homogeneous immunoassay
US4560881A (en) * 1984-03-13 1985-12-24 Syntex (U.S.A.) Inc. Method and apparatus for enhanced detection of electromagnetic signals

Also Published As

Publication number Publication date
AU4737485A (en) 1986-03-20
EP0175545A2 (de) 1986-03-26
US4676640A (en) 1987-06-30
DE3586380T2 (de) 1993-03-11
CA1277505C (en) 1990-12-11
JPH052180B2 (de) 1993-01-11
EP0175545A3 (en) 1987-07-29
EP0175545B1 (de) 1992-07-22
AU584351B2 (en) 1989-05-25
ATE78586T1 (de) 1992-08-15
JPS6183938A (ja) 1986-04-28

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee