DE3584705D1 - Endotoxin von gram-negativ-bakterien blockierende monoklonale antikoerper, zellen die diese produzieren, zubereitungen die diese enthalten und verfahren zur herstellung dieser produkte. - Google Patents
Endotoxin von gram-negativ-bakterien blockierende monoklonale antikoerper, zellen die diese produzieren, zubereitungen die diese enthalten und verfahren zur herstellung dieser produkte.Info
- Publication number
- DE3584705D1 DE3584705D1 DE8585306329T DE3584705T DE3584705D1 DE 3584705 D1 DE3584705 D1 DE 3584705D1 DE 8585306329 T DE8585306329 T DE 8585306329T DE 3584705 T DE3584705 T DE 3584705T DE 3584705 D1 DE3584705 D1 DE 3584705D1
- Authority
- DE
- Germany
- Prior art keywords
- producing
- endotoxin
- preparations
- cells
- products
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1203—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1203—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
- C07K16/1228—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
- C07K16/1232—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia from Escherichia (G)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1203—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
- C07K16/1228—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
- C07K16/1235—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia from Salmonella (G)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
- G01N2333/24—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
- G01N2333/245—Escherichia (G)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
- G01N2333/24—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
- G01N2333/255—Salmonella (G)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2400/00—Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
- G01N2400/10—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- G01N2400/50—Lipopolysaccharides; LPS
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Communicable Diseases (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US64761184A | 1984-09-05 | 1984-09-05 | |
US72782185A | 1985-04-26 | 1985-04-26 |
Publications (1)
Publication Number | Publication Date |
---|---|
DE3584705D1 true DE3584705D1 (de) | 1992-01-02 |
Family
ID=27095206
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE8585306329T Expired - Fee Related DE3584705D1 (de) | 1984-09-05 | 1985-09-05 | Endotoxin von gram-negativ-bakterien blockierende monoklonale antikoerper, zellen die diese produzieren, zubereitungen die diese enthalten und verfahren zur herstellung dieser produkte. |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0174204B1 (de) |
JP (1) | JPH0659233B2 (de) |
DE (1) | DE3584705D1 (de) |
DK (1) | DK405785A (de) |
FI (1) | FI853395L (de) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5179018A (en) * | 1983-10-14 | 1993-01-12 | Centocor, Inc. | Mamalian monoclonal antibodies against endotoxin of gram-negative bacteria |
US4844894A (en) * | 1984-07-12 | 1989-07-04 | Ribi Immunochem Research Inc. | Method of inhibiting the onset of septicemia and endotoxemia |
US4777136A (en) * | 1985-09-27 | 1988-10-11 | The Regents Of The University Of California | Monoclonal antibody reactive with Pseudomonas Aeruginosa |
US4918163A (en) * | 1985-09-27 | 1990-04-17 | Pfizer Inc. | Monoclonal antibodies specific for lipid-A determinants of gram negative bacteria |
US5179001A (en) * | 1985-09-27 | 1993-01-12 | The Regents Of The University Of California | Detection and monitoring of chronic and gram-negative infection |
ES2009365A6 (es) * | 1986-04-24 | 1989-09-16 | Univ California | Procedimiento de otencion de anticuerpos monoclonales para bacterias gram-negativas. |
EP0256713A3 (de) * | 1986-08-06 | 1989-02-15 | Merck & Co. Inc. | Therapeutische, menschliche Antipseudomonas-Aeruginosa-Antikörper |
US5001065A (en) * | 1987-05-27 | 1991-03-19 | Cetus Corporation | Human cell line and triomas, antibodies, and transformants derived therefrom |
JPH04500601A (ja) * | 1988-09-19 | 1992-02-06 | シタス コーポレイション | グラム陰性細菌エンドトキシンブロッキングモノクローナル抗体 |
CA1341375C (en) * | 1988-10-12 | 2002-07-09 | Baxter International Inc. | Compositions and methods for the treatment and prevention of gram-negative bacterial infections |
DE3843784A1 (de) * | 1988-12-24 | 1990-06-28 | Battelle Institut E V | Verfahren zum nachweis von gramnegativen mikroorganismen sowie hierfuer geeignete dna-proben und antikoerper |
US6586222B1 (en) | 1989-08-16 | 2003-07-01 | Chiron Corporation | Recombinant PR-3 and compositions thereof |
DK0491878T3 (da) | 1989-08-16 | 1997-06-23 | Chiron Corp | Præparater til inhibering af proteinhormondannelse og anvendelser deraf |
US5998378A (en) * | 1989-08-16 | 1999-12-07 | Chiron Corporation | Compositions for the inhibition of TNF hormone formation and uses thereof |
US5843693A (en) * | 1989-08-16 | 1998-12-01 | Chiron Corporation | Assay method for screening for inhibitors of proTNF conversion |
WO1995024501A1 (en) | 1994-03-07 | 1995-09-14 | Cetus Oncology Corporation | Compositions for the inhibition of tnf formation and uses thereof |
JPH08324578A (ja) * | 1995-06-02 | 1996-12-10 | Atena Shoji Kk | 往復通信用封筒 |
US6790661B1 (en) | 1999-07-16 | 2004-09-14 | Verax Biomedical, Inc. | System for detecting bacteria in blood, blood products, and fluids of tissues |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1262238A (en) * | 1982-09-30 | 1989-10-10 | Richard Insel | Human monoclonal antibodies against bacterial toxins |
WO1984004458A1 (en) * | 1983-05-06 | 1984-11-22 | Matthew Pollack | Monoclonal antibodies reactive with endotoxin core |
US5179018A (en) * | 1983-10-14 | 1993-01-12 | Centocor, Inc. | Mamalian monoclonal antibodies against endotoxin of gram-negative bacteria |
WO1985002685A1 (en) * | 1983-12-12 | 1985-06-20 | Meru, Inc. | Method and materials for the identification of lipopolysaccharide producing microorganisms |
-
1985
- 1985-09-04 FI FI853395A patent/FI853395L/fi not_active Application Discontinuation
- 1985-09-05 DK DK405785A patent/DK405785A/da not_active Application Discontinuation
- 1985-09-05 DE DE8585306329T patent/DE3584705D1/de not_active Expired - Fee Related
- 1985-09-05 JP JP60194981A patent/JPH0659233B2/ja not_active Expired - Lifetime
- 1985-09-05 EP EP85306329A patent/EP0174204B1/de not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP0174204B1 (de) | 1991-11-21 |
DK405785D0 (da) | 1985-09-05 |
EP0174204A2 (de) | 1986-03-12 |
JPS6172800A (ja) | 1986-04-14 |
EP0174204A3 (en) | 1986-06-18 |
DK405785A (da) | 1986-03-06 |
FI853395L (fi) | 1986-03-06 |
FI853395A0 (fi) | 1985-09-04 |
JPH0659233B2 (ja) | 1994-08-10 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |