ES2009365A6 - Procedimiento de otencion de anticuerpos monoclonales para bacterias gram-negativas. - Google Patents
Procedimiento de otencion de anticuerpos monoclonales para bacterias gram-negativas.Info
- Publication number
- ES2009365A6 ES2009365A6 ES8803335A ES8803335A ES2009365A6 ES 2009365 A6 ES2009365 A6 ES 2009365A6 ES 8803335 A ES8803335 A ES 8803335A ES 8803335 A ES8803335 A ES 8803335A ES 2009365 A6 ES2009365 A6 ES 2009365A6
- Authority
- ES
- Spain
- Prior art keywords
- gram negative
- humans
- bacterial infections
- negative bacterial
- treating gram
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1203—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1203—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
- C07K16/1214—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Pseudomonadaceae (F)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/77—Internalization into the cell
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
- G01N2333/21—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Pseudomonadaceae (F)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2400/00—Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
- G01N2400/10—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- G01N2400/50—Lipopolysaccharides; LPS
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
PROCEDIMIENTO DE OBTENCION DE ANTICUERPOS MONOCLONALES PARA BACTERIAS GRAM-NEGATIVAS, EN EL QUE SE INYECTA EN UN RATON UN AGENTE PROMOTOR DE TUMORES, SE INOCULAN EN DICHO RATON, DESPUES DE DICHA INYECCION, CELULAS DE UN HIBRIDOMA SELECCIONADO ENTRE XMMEN-J5D, NUMERO DE ADMISION A.T.C.C. HB 9083, XMMEN-OE5, NUMERO DE ADMISION A.T.C.C. HB 9081, XMMEN-LY1, NUMERO DE ADMISION A.T.C.C. HB 9082, XMMPS-OP1, NUMERO DE ADMISION A.T.C.C. HB 9384, SE RECOGE EL FLUIDO ASCITICO DE DICHO RATON Y SE PURIFICAN LOS ANTICUERPOS DE DICHO FLUIDO ASCITICO MEDIANTE CROMATOGRAFIA DE AFINIDAD. EL INVENTO ES ESPECIALMENTE UTIL EN RELACION CON INFECCIONES CAUSADAS POR BACTERIAS GRAM-NEGATIVAS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/855,878 US4918163A (en) | 1985-09-27 | 1986-04-24 | Monoclonal antibodies specific for lipid-A determinants of gram negative bacteria |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2009365A6 true ES2009365A6 (es) | 1989-09-16 |
Family
ID=25322328
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES8803336A Expired ES2009366A6 (es) | 1986-04-24 | 1988-11-02 | Procedimiento de obtencion de anticuerpos monoclonales para bacterias gram-negativas. |
ES8803335A Expired ES2009365A6 (es) | 1986-04-24 | 1988-11-02 | Procedimiento de otencion de anticuerpos monoclonales para bacterias gram-negativas. |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES8803336A Expired ES2009366A6 (es) | 1986-04-24 | 1988-11-02 | Procedimiento de obtencion de anticuerpos monoclonales para bacterias gram-negativas. |
Country Status (2)
Country | Link |
---|---|
US (1) | US5698198A (es) |
ES (2) | ES2009366A6 (es) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5959087A (en) * | 1989-08-07 | 1999-09-28 | Peptide Technology, Ltd. | Tumour necrosis factor binding ligands |
US6790661B1 (en) * | 1999-07-16 | 2004-09-14 | Verax Biomedical, Inc. | System for detecting bacteria in blood, blood products, and fluids of tissues |
US7132101B2 (en) * | 2002-02-27 | 2006-11-07 | Duquesne University Of The Holy Ghost | Compositions and methods for eliciting an immune response to gram-negative bacterial infections |
Family Cites Families (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4647447A (en) * | 1981-07-24 | 1987-03-03 | Schering Aktiengesellschaft | Diagnostic media |
US4443549A (en) * | 1981-10-19 | 1984-04-17 | Molecular Genetics, Inc. | Production of monoclonal antibodies against bacterial adhesins |
US4428931A (en) * | 1982-03-15 | 1984-01-31 | Merck & Co., Inc. | Bacterial toxoids and gram-negative immune globulin therefrom |
US4464465A (en) * | 1982-04-05 | 1984-08-07 | Genetic Systems Corporation | Cell-driven viral transfer in eukaryotes |
FI69639C (fi) * | 1982-07-02 | 1986-03-10 | Orion Yhtymae Oy | Preparat foer anvaendning vid klamydia-diagnostik |
JPS5929622A (ja) * | 1982-08-10 | 1984-02-16 | Meiji Seika Kaisha Ltd | モノクロ−ナル抗体、その製造法およびその用途 |
US4689299A (en) * | 1982-09-30 | 1987-08-25 | University Of Rochester | Human monoclonal antibodies against bacterial toxins |
US4525453A (en) * | 1982-10-26 | 1985-06-25 | Eastman Kodak Company | Process for rapidly differentiating between gram-negative and gram-positive microorganisms |
US4574116A (en) * | 1983-01-13 | 1986-03-04 | The Board Of Trustees Of The Leland Stanford Jr. University | Methods and cell lines for immortalization and monoclonal antibody production by antigen-stimulated B-lymphocytes |
AU585200B2 (en) * | 1983-05-06 | 1989-06-15 | Velos Group | Monoclonal antibodies reactive with endotoxin core |
US5057598A (en) * | 1983-05-06 | 1991-10-15 | Centocor, Inc. | Monoclonal antibodies reactive with endotoxin core |
US4587121A (en) * | 1983-06-14 | 1986-05-06 | Miles Laboratories, Inc. | High titer Pseudomonas immune serum globulin |
US5179018A (en) * | 1983-10-14 | 1993-01-12 | Centocor, Inc. | Mamalian monoclonal antibodies against endotoxin of gram-negative bacteria |
US4617264A (en) * | 1983-11-04 | 1986-10-14 | Syntex (U.S.A.) Inc. | Pretreatment method and composition |
US4683196A (en) * | 1983-12-12 | 1987-07-28 | Meru, Inc. | Method and materials for the identification of lipopolysaccharide producing microorganisms |
US4834975A (en) * | 1984-05-25 | 1989-05-30 | Genetics Corporation | Human monoclonal antibodies to serotypic lipopolysaccharide determinants on gram-negative bacteria and their production |
FI853395L (fi) * | 1984-09-05 | 1986-03-06 | Cetus Corp | Monoklonala antikroppar som blockerar gram-negativ bakterieendotoxin. |
JP2691708B2 (ja) * | 1984-09-26 | 1997-12-17 | 住友製薬株式会社 | ヒトモノクローナル抗体およびその製法 |
EP0183876A1 (en) * | 1984-11-27 | 1986-06-11 | The Board Of Trustees Of The Leland Stanford Junior University | Monoclonal antibodies for endotoxin core and their use |
EP0233289B1 (en) * | 1984-12-26 | 1993-03-10 | Teijin Limited | Hybridomas producing anti-pseudomonas aeruginosa human monoclonal antibody |
USH1198H (en) * | 1985-04-26 | 1993-06-01 | Cetus Corporation | Pseudomonas aeruginosa type-specific human monoclonal antibodies, their preparation and use |
-
1988
- 1988-11-02 ES ES8803336A patent/ES2009366A6/es not_active Expired
- 1988-11-02 ES ES8803335A patent/ES2009365A6/es not_active Expired
-
1995
- 1995-06-06 US US08/466,327 patent/US5698198A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
ES2009366A6 (es) | 1989-09-16 |
US5698198A (en) | 1997-12-16 |
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