DE3582973D1 - Neues derivat des humangammainterferon-polypeptids. - Google Patents

Neues derivat des humangammainterferon-polypeptids.

Info

Publication number
DE3582973D1
DE3582973D1 DE8585108541T DE3582973T DE3582973D1 DE 3582973 D1 DE3582973 D1 DE 3582973D1 DE 8585108541 T DE8585108541 T DE 8585108541T DE 3582973 T DE3582973 T DE 3582973T DE 3582973 D1 DE3582973 D1 DE 3582973D1
Authority
DE
Germany
Prior art keywords
humangamma
amino acids
new derivative
interferon polypeptide
polypeptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8585108541T
Other languages
English (en)
Inventor
Seiga Itoh
Yasutoshi Takeichi
Moriyuki Sato
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KH Neochem Co Ltd
Original Assignee
Kyowa Hakko Kogyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=15350817&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE3582973(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Kyowa Hakko Kogyo Co Ltd filed Critical Kyowa Hakko Kogyo Co Ltd
Application granted granted Critical
Publication of DE3582973D1 publication Critical patent/DE3582973D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C12N15/71—Expression systems using regulatory sequences derived from the trp-operon
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/57—IFN-gamma

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE8585108541T 1984-07-11 1985-07-09 Neues derivat des humangammainterferon-polypeptids. Expired - Lifetime DE3582973D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP14395084A JPS6124599A (ja) 1984-07-11 1984-07-11 新規ヒトインタ−フエロン−ｒポリペプチド誘導体

Publications (1)

Publication Number Publication Date
DE3582973D1 true DE3582973D1 (de) 1991-07-04

Family

ID=15350817

Family Applications (2)

Application Number Title Priority Date Filing Date
DE8585108541T Expired - Lifetime DE3582973D1 (de) 1984-07-11 1985-07-09 Neues derivat des humangammainterferon-polypeptids.
DE198585108541T Pending DE170917T1 (de) 1984-07-11 1985-07-09 Neues derivat des humangammainterferon-polypeptids.

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE198585108541T Pending DE170917T1 (de) 1984-07-11 1985-07-09 Neues derivat des humangammainterferon-polypeptids.

Country Status (11)

Country Link
US (1) US4898931A (de)
EP (1) EP0170917B1 (de)
JP (1) JPS6124599A (de)
AT (1) ATE63923T1 (de)
AU (1) AU586822B2 (de)
CA (1) CA1303529C (de)
DE (2) DE3582973D1 (de)
DK (1) DK164108C (de)
ES (1) ES8609484A1 (de)
IL (1) IL75738A (de)
NO (1) NO175487C (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8334102D0 (en) * 1983-12-21 1984-02-01 Searle & Co Interferons with cysteine pattern
CA1340265C (en) * 1985-01-18 1998-12-15 Kirston E. Koths Oxidation resistant muteins
GB8619725D0 (en) * 1986-08-13 1986-09-24 Hoffmann La Roche Homogenous interferon fragments
JP2653061B2 (ja) * 1986-12-27 1997-09-10 武田薬品工業株式会社 新規ポリペプチドおよびその製造法
AT393690B (de) * 1987-10-08 1991-11-25 Hoffmann La Roche Homogene, rekombinante immun-interferonfragmente
DE3829180A1 (de) * 1988-08-29 1990-03-08 Boehringer Ingelheim Int Neues arzneimittel zur vorbeugung und behandlung von durch primaere immundefekte verursachte krankheiten
DE4036856C1 (de) * 1990-11-19 1992-05-27 Fraunhofer-Gesellschaft Zur Foerderung Der Angewandten Forschung Ev, 8000 Muenchen, De
CN1900116A (zh) * 1995-01-26 2007-01-24 拜奥根Idec马萨诸塞公司 抗－LT－β－R抗体、含有该抗体的药用组合物及其制药应用
DE19535853C2 (de) * 1995-09-18 1999-04-01 Fraunhofer Ges Forschung Varianten des rekombinanten humanen Interferon-gamma, Verfahren zu ihrer Herstellung und ihre Verwendung
JP2003513681A (ja) * 1999-11-12 2003-04-15 マキシゲン・ホールディングス・リミテッド インターフェロンガンマ・コンジュゲート
CN1309423C (zh) 1999-11-12 2007-04-11 马克西根控股公司 干扰素γ偶联物
AU782635B2 (en) * 1999-11-12 2005-08-18 Maxygen Holdings Ltd. Interferon gamma conjugates
US6958388B2 (en) 2001-04-06 2005-10-25 Maxygen, Aps Interferon gamma polypeptide variants
US7038015B2 (en) 2001-04-06 2006-05-02 Maxygen Holdings, Ltd. Interferon gamma polypeptide variants
US7524931B2 (en) 2002-07-03 2009-04-28 Maxygen Holdings Ltd. Full-length interferon gamma polypeptide variants
JP4896745B2 (ja) 2004-02-02 2012-03-14 アンブレツクス・インコーポレイテツド 修飾されたヒトインターフェロンポリペプチドおよびこれらの使用
CA2609205A1 (en) * 2005-06-03 2006-12-14 Ambrx, Inc. Improved human interferon molecules and their uses
EP1991679A2 (de) * 2006-03-08 2008-11-19 Biomethodes Varianten des humanen interferon-gamma (ifngamma)
FR2898359B1 (fr) * 2006-03-08 2011-07-15 Biomethodes Variants ameliores de l'interferon-gamma humain (ifn gamma)
CA2712606A1 (en) 2008-02-08 2009-08-13 Ambrx, Inc. Modified leptin polypeptides and their uses
MX2021001165A (es) * 2018-07-30 2021-07-15 Univ Leland Stanford Junior Agonistas sesgados de interferon-gamma.

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU561343B2 (en) * 1981-10-19 1987-05-07 Genentech Inc. Human immune interferon by recombinant dna
JPS58110548A (ja) * 1981-12-24 1983-07-01 Asahi Chem Ind Co Ltd 新規な生理活性ペプチド
US6936694B1 (en) * 1982-05-06 2005-08-30 Intermune, Inc. Manufacture and expression of large structural genes
JPH0787797B2 (ja) * 1982-05-20 1995-09-27 サントリー株式会社 ヒト・ガンマ・インタ−フエロン様ポリペプチドの製造法
US4681848A (en) * 1982-09-22 1987-07-21 Takeda Chemical Industries, Ltd. Novel peptide and use thereof
IL69851A0 (en) * 1982-09-30 1983-12-30 Japan Found Cancer Novel dna and recombinant plasmid containing the same
US4758656A (en) * 1983-12-26 1988-07-19 Kyowa Hakko Kogyo Co., Ltd. Novel human interferon-gamma polypeptide derivative
AU582574B2 (en) * 1984-04-19 1989-04-06 Hoechst Aktiengesellschaft The preparation of polypeptides having human gamma interferon activity
IL75302A0 (en) * 1984-06-06 1985-09-29 Takeda Chemical Industries Ltd Novel polypeptide and production thereof

Also Published As

Publication number Publication date
ATE63923T1 (de) 1991-06-15
EP0170917A1 (de) 1986-02-12
ES545052A0 (es) 1986-09-01
EP0170917B1 (de) 1991-05-29
DK314485D0 (da) 1985-07-10
CA1303529C (en) 1992-06-16
NO852776L (no) 1986-01-13
NO175487C (no) 1994-10-19
DK164108B (da) 1992-05-11
NO175487B (no) 1994-07-11
AU4474985A (en) 1986-01-16
DK164108C (da) 1992-10-12
ES8609484A1 (es) 1986-09-01
IL75738A0 (en) 1985-11-29
AU586822B2 (en) 1989-07-27
JPS6124599A (ja) 1986-02-03
IL75738A (en) 1995-06-29
DE170917T1 (de) 1986-09-04
DK314485A (da) 1986-01-12
US4898931A (en) 1990-02-06

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Legal Events

Date Code Title Description
8363 Opposition against the patent
8365 Fully valid after opposition proceedings
8339 Ceased/non-payment of the annual fee