DE3581188D1 - Klebende schicht zur transdermalen freigabe. - Google Patents

Klebende schicht zur transdermalen freigabe.

Info

Publication number
DE3581188D1
DE3581188D1 DE8585903926T DE3581188T DE3581188D1 DE 3581188 D1 DE3581188 D1 DE 3581188D1 DE 8585903926 T DE8585903926 T DE 8585903926T DE 3581188 T DE3581188 T DE 3581188T DE 3581188 D1 DE3581188 D1 DE 3581188D1
Authority
DE
Germany
Prior art keywords
component layer
pharmaceutically active
active drug
skin
sheet
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8585903926T
Other languages
German (de)
English (en)
Inventor
Steve Sablotsky
John Questel
James Thompson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Key Pharmaceuticals Inc
Original Assignee
Key Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24541997&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE3581188(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Key Pharmaceuticals Inc filed Critical Key Pharmaceuticals Inc
Application granted granted Critical
Publication of DE3581188D1 publication Critical patent/DE3581188D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE8585903926T 1984-07-24 1985-07-24 Klebende schicht zur transdermalen freigabe. Expired - Lifetime DE3581188D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US63399284A 1984-07-24 1984-07-24
PCT/US1985/001401 WO1986000814A1 (en) 1984-07-24 1985-07-24 Adhesive transdermal dosage layer

Publications (1)

Publication Number Publication Date
DE3581188D1 true DE3581188D1 (de) 1991-02-07

Family

ID=24541997

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8585903926T Expired - Lifetime DE3581188D1 (de) 1984-07-24 1985-07-24 Klebende schicht zur transdermalen freigabe.

Country Status (11)

Country Link
US (1) US5186938A (enExample)
EP (1) EP0190262B1 (enExample)
JP (1) JPS61502760A (enExample)
AT (1) ATE59302T1 (enExample)
AU (1) AU576889B2 (enExample)
DE (1) DE3581188D1 (enExample)
FI (1) FI85106C (enExample)
HK (1) HK94093A (enExample)
MY (1) MY100249A (enExample)
NO (1) NO171950C (enExample)
WO (1) WO1986000814A1 (enExample)

Families Citing this family (103)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4751087A (en) * 1985-04-19 1988-06-14 Riker Laboratories, Inc. Transdermal nitroglycerin delivery system
EP0268680A4 (de) * 1986-05-29 1990-04-10 Vnii Ispytatel Med Tech Antitumorfilm aus biologisch abbaubaren polymeren.
AU607172B2 (en) * 1986-12-22 1991-02-28 Cygnus, Inc. Diffusion matrix for transdermal drug administration
DE3643987A1 (de) * 1986-12-22 1988-06-23 Lohmann Therapie Syst Lts Basische, wirkstoffdurchlaessige haftklebende polymermasse, insbesondere zum einsatz mit basischen wirkstoffen, verfahren zu ihrer herstellung und ihre verwendung
US4818541A (en) * 1987-08-19 1989-04-04 Schering Corporation Transdermal delivery of enantiomers of phenylpropanolamine
DE3823070A1 (de) * 1988-07-07 1990-02-22 Kettelhack Riker Pharma Gmbh Selbstklebendes heftpflaster
CA2065311C (en) * 1989-09-08 2000-01-11 Chia-Ming Chiang Solid matrix system for transdermal drug delivery
US5252334A (en) * 1989-09-08 1993-10-12 Cygnus Therapeutic Systems Solid matrix system for transdermal drug delivery
JP3273430B2 (ja) * 1989-12-28 2002-04-08 日東電工株式会社 エストロゲン含有ゲル製剤
US5204109A (en) * 1989-12-28 1993-04-20 Nitto Denko Corporation Percutaneous gel preparation
EP0436203B1 (en) * 1989-12-28 1996-04-03 Nitto Denko Corporation Percutaneous gel preparation
JPH07116032B2 (ja) * 1990-04-06 1995-12-13 積水化学工業株式会社 ニトログリセリン貼付剤
US5202125A (en) * 1990-12-10 1993-04-13 Theratech, Inc. Method and systems for administering nitroglycerin transdermally at enhanced transdermal fluxes
JPH04261119A (ja) * 1991-02-13 1992-09-17 Lintec Corp 経皮吸収型貼付剤
WO1992022292A1 (de) 1991-06-10 1992-12-23 Schwarz Pharma Ag Nitroglycerin-pflaster und verfahren zu seiner herstellung
DE4229230C2 (de) * 1992-09-02 1997-01-16 Lohmann Therapie Syst Lts Transdermales therapeutisches System mit Pentetrazol als Wirkstoff
US5489624A (en) * 1992-12-01 1996-02-06 Minnesota Mining And Manufacturing Company Hydrophilic pressure sensitive adhesives
US5762952A (en) * 1993-04-27 1998-06-09 Hercon Laboratories Corporation Transdermal delivery of active drugs
US5613958A (en) * 1993-05-12 1997-03-25 Pp Holdings Inc. Transdermal delivery systems for the modulated administration of drugs
EP0717761A4 (en) * 1993-08-19 1998-01-07 Cygnus Therapeutic Systems WATER-SOLUBLE, PRESSURE-SENSITIVE AND MUCOADHESIVE ADHESIVE AND DEVICE FOR POSITIONING IT IN A MUCUTINE BODY CAVE
DE4403487C2 (de) * 1994-02-04 2003-10-16 Lohmann Therapie Syst Lts Arznei-Pflaster mit UV-vernetzbaren Acrylat-Copolymeren
AU5299996A (en) * 1995-02-23 1996-09-11 Cygnus, Inc. Water-soluble pressure-sensitive mucoadhesive
US5601839A (en) * 1995-04-26 1997-02-11 Theratech, Inc. Triacetin as a penetration enhancer for transdermal delivery of a basic drug
US5985317A (en) * 1996-09-06 1999-11-16 Theratech, Inc. Pressure sensitive adhesive matrix patches for transdermal delivery of salts of pharmaceutical agents
DE19706824C1 (de) 1997-02-21 1998-03-26 Lohmann Therapie Syst Lts Transdermales oder topisches Plastersystem mit Polyacrylatmatrix mit verbesserten physikalischen Eigenschaften
GB9704022D0 (en) * 1997-02-26 1997-04-16 York Rehabilitation Limited Protective barrier composition
US20020018754A1 (en) * 1999-03-15 2002-02-14 Paul Albert Sagel Shapes for tooth whitening strips
US6096328A (en) * 1997-06-06 2000-08-01 The Procter & Gamble Company Delivery system for an oral care substance using a strip of material having low flexural stiffness
GB9714650D0 (en) * 1997-07-11 1997-09-17 Strakan Ltd Block copolymer
US6183770B1 (en) 1999-04-15 2001-02-06 Acutek International Carrier patch for the delivery of agents to the skin
AU5907300A (en) 1999-07-02 2001-01-22 Procter & Gamble Company, The Compositions comprising organosiloxane resins for delivering xylitol to the oralcavity
US6890553B1 (en) 1999-07-08 2005-05-10 Johnson & Johnson Consumer Companies, Inc. Exothermic topical delivery device
DE19940238A1 (de) 1999-08-25 2001-03-01 Lohmann Therapie Syst Lts Wirkstoffhaltiges therapeutisches System zur Applikation auf der Haut mit mindestens zwei polymerhaltigen Schichten
EP1318843B1 (en) * 2000-09-19 2013-04-17 Henkel AG & Co. KGaA Acryl adhesive useful in transdermal drug delivery systems
US6709716B2 (en) * 2001-04-27 2004-03-23 3M Innovative Properties Company Microemulsion compositions and methods of making and using same
US20070281003A1 (en) * 2001-10-12 2007-12-06 Fuisz Richard C Polymer-Based Films and Drug Delivery Systems Made Therefrom
US20190328679A1 (en) 2001-10-12 2019-10-31 Aquestive Therapeutics, Inc. Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions
US20060039958A1 (en) * 2003-05-28 2006-02-23 Monosolrx, Llc. Multi-layer films having uniform content
US7425292B2 (en) * 2001-10-12 2008-09-16 Monosol Rx, Llc Thin film with non-self-aggregating uniform heterogeneity and drug delivery systems made therefrom
US7666337B2 (en) * 2002-04-11 2010-02-23 Monosol Rx, Llc Polyethylene oxide-based films and drug delivery systems made therefrom
US8765167B2 (en) * 2001-10-12 2014-07-01 Monosol Rx, Llc Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions
US8603514B2 (en) 2002-04-11 2013-12-10 Monosol Rx, Llc Uniform films for rapid dissolve dosage form incorporating taste-masking compositions
US8900497B2 (en) 2001-10-12 2014-12-02 Monosol Rx, Llc Process for making a film having a substantially uniform distribution of components
US20110033542A1 (en) 2009-08-07 2011-02-10 Monosol Rx, Llc Sublingual and buccal film compositions
US7357891B2 (en) 2001-10-12 2008-04-15 Monosol Rx, Llc Process for making an ingestible film
US20100021526A1 (en) * 2001-10-12 2010-01-28 Monosol Rx, Llc Ph modulated films for delivery of actives
US7910641B2 (en) * 2001-10-12 2011-03-22 Monosol Rx, Llc PH modulated films for delivery of actives
US11207805B2 (en) 2001-10-12 2021-12-28 Aquestive Therapeutics, Inc. Process for manufacturing a resulting pharmaceutical film
US8900498B2 (en) 2001-10-12 2014-12-02 Monosol Rx, Llc Process for manufacturing a resulting multi-layer pharmaceutical film
US20070154527A1 (en) * 2001-10-12 2007-07-05 Monosoirx, Llc Topical film compositions for delivery of actives
US8663687B2 (en) 2001-10-12 2014-03-04 Monosol Rx, Llc Film compositions for delivery of actives
US10285910B2 (en) 2001-10-12 2019-05-14 Aquestive Therapeutics, Inc. Sublingual and buccal film compositions
US8017150B2 (en) * 2002-04-11 2011-09-13 Monosol Rx, Llc Polyethylene oxide-based films and drug delivery systems made therefrom
JP4295467B2 (ja) 2002-04-12 2009-07-15 日東電工株式会社 貼付剤およびその製造方法
US6949240B2 (en) * 2002-05-23 2005-09-27 The Procter & Gamble Company Tooth whitening products
JP4323138B2 (ja) * 2002-06-05 2009-09-02 日東電工株式会社 経皮吸収型製剤およびその製造方法
CA2505796C (en) * 2002-07-22 2012-01-03 Monosolrx Llc Packaging and dispensing of rapid dissolve dosage form
US8524200B2 (en) 2002-09-11 2013-09-03 The Procter & Gamble Company Tooth whitening products
US20050019277A1 (en) * 2002-09-11 2005-01-27 The Procter & Gamble Company Tooth whitening products
US20070059351A1 (en) * 2003-10-17 2007-03-15 Murrell George A C Transdermal patches containing a nitric oxide-donor and a second active agent and associated methods
US20060286159A1 (en) * 2003-10-17 2006-12-21 Calvert Murrell George A Treatment of persistent active tendinopathy using transdermal glyceryl trinitrate providing durability of effect
US20070053966A1 (en) * 2003-10-17 2007-03-08 Robert Ang Medicated orthopedic support structures for treatment of damaged musculoskeletal tissue
US20060286158A1 (en) * 2003-10-17 2006-12-21 Calvert Murrell George A Treatment of overuse tendinopathy using transdermal nitric oxide-generating agents
US7619007B2 (en) 2004-11-23 2009-11-17 Adamas Pharmaceuticals, Inc. Method and composition for administering an NMDA receptor antagonist to a subject
BRPI0518483A2 (pt) 2004-11-23 2008-11-18 Neuromolecular Pharmaceuticals Inc composiÇço compreendendo uma matriz ou revestimento de liberaÇço controlada e um antagonista de receptor de nmda, mÉtodo para administraÇço de tal antagonista de nmda a um paciente
BRPI0607017B8 (pt) 2005-04-06 2021-05-25 Adamas Pharmaceuticals Inc composição farmacêutica compreendendo memantina e donezepil, e seu uso para o tratamento de condições relacionadas ao snc
US20070212703A1 (en) * 2005-09-27 2007-09-13 Stemmer Willem P Proteinaceous pharmaceuticals and uses thereof
US7846445B2 (en) * 2005-09-27 2010-12-07 Amunix Operating, Inc. Methods for production of unstructured recombinant polymers and uses thereof
US20090099031A1 (en) * 2005-09-27 2009-04-16 Stemmer Willem P Genetic package and uses thereof
US7855279B2 (en) 2005-09-27 2010-12-21 Amunix Operating, Inc. Unstructured recombinant polymers and uses thereof
CA2636026A1 (en) * 2006-01-20 2007-07-26 Monosol Rx, Llc Film lined pouch and method of manufacturing this pouch
US20070202155A1 (en) * 2006-02-03 2007-08-30 Cure Therapeutics, Inc. Low dose no donor-containing transdermal patch
US20070259026A1 (en) * 2006-04-20 2007-11-08 Robert Ang Vasodialating dressing for use with intravenous catheters
CN101516331A (zh) * 2006-09-20 2009-08-26 莫诺索尔克斯有限公司 含有抗泡沫调味剂的可食用水溶性膜
US20080081071A1 (en) * 2006-09-29 2008-04-03 Pradeep Sanghvi Film Embedded Packaging and Method of Making Same
BRPI0815416A2 (pt) * 2007-08-15 2014-10-21 Amunix Inc Composições e métodos para modificar propriedades de polipeptídeos biologicamente ativos
WO2010091122A1 (en) * 2009-02-03 2010-08-12 Amunix, Inc. Extended recombinant polypeptides and compositions comprising same
AU2010258892B2 (en) 2009-06-08 2015-08-13 Amunix Operating Inc. Growth hormone polypeptides and methods of making and using same
AU2010258898B8 (en) 2009-06-08 2015-02-05 Amunix Operating Inc. Glucose-regulating polypeptides and methods of making and using same
US8475832B2 (en) 2009-08-07 2013-07-02 Rb Pharmaceuticals Limited Sublingual and buccal film compositions
BR112012004094A2 (pt) 2009-08-24 2016-03-08 Amunix Operating Inc composições de fator vii de coagulação e métodos para fazer e usar as mesmas
CN106389381A (zh) 2009-12-02 2017-02-15 阿达玛斯医药公司 金刚烷胺组合物及其使用方法
EP4450523A3 (en) 2010-04-02 2025-03-12 Amunix Pharmaceuticals, Inc. Binding fusion proteins, binding fusion protein-drug conjugates, xten-drug conjugates and methods of making and using same
ES2569339T3 (es) 2010-06-10 2016-05-10 Midatech Ltd. Sistemas de administración de película de nanopartículas
DE102010024105A1 (de) * 2010-06-17 2011-12-22 Grünenthal GmbH Transdermale Verabreichung von Memantin
US9149959B2 (en) 2010-10-22 2015-10-06 Monosol Rx, Llc Manufacturing of small film strips
LT2822577T (lt) 2012-02-15 2019-03-25 Bioverativ Therapeutics Inc. Rekombinantiniai faktoriaus viii baltymai
HRP20221531T1 (hr) 2012-02-15 2023-02-17 Bioverativ Therapeutics Inc. Pripravci faktora viii i postupci dobivanja i korištenja istih
CA2888199C (en) 2012-10-17 2019-06-25 The Procter & Gamble Company Strip for the delivery of an oral care active and methods for applying oral care actives
US10154971B2 (en) 2013-06-17 2018-12-18 Adamas Pharma, Llc Methods of administering amantadine
EP3033097B1 (en) 2013-08-14 2021-03-10 Bioverativ Therapeutics Inc. Factor viii-xten fusions and uses thereof
MX2018001497A (es) 2015-08-03 2018-05-15 Bioverativ Therapeutics Inc Proteinas de fusion de factor ix y metodos para producirlas y usarlas.
US12433850B2 (en) 2016-05-05 2025-10-07 Aquestive Therapeutics, Inc. Enhanced delivery epinephrine and prodrug compositions
US11273131B2 (en) 2016-05-05 2022-03-15 Aquestive Therapeutics, Inc. Pharmaceutical compositions with enhanced permeation
KR20230137362A (ko) 2016-05-05 2023-10-04 어퀘스티브 테라퓨틱스, 아이엔씨. 강화된 전달 에프네프린 조성물
US12427121B2 (en) 2016-05-05 2025-09-30 Aquestive Therapeutics, Inc. Enhanced delivery epinephrine compositions
US20180104250A1 (en) 2016-10-14 2018-04-19 Knowles Enterprises Inc. Formulations for treatment of migraines
WO2018102743A1 (en) 2016-12-02 2018-06-07 Bioverativ Therapeutics Inc. Methods of treating hemophilic arthropathy using chimeric clotting factors
WO2018200885A1 (en) 2017-04-26 2018-11-01 Neurocentria, Inc. Magnesium compositions and methods of use
RS66972B1 (sr) 2018-05-18 2025-07-31 Bioverativ Therapeutics Inc Metode lečenja hemofilije a
CN109453414A (zh) * 2018-09-26 2019-03-12 南阳市中心医院 一种肝胆外科术后抗感染的敷料
CA3182372A1 (en) 2020-06-25 2021-12-30 Amunix Pharmaceuticals, Inc. Her-2 targeted bispecific compositions and methods for making and using the same
WO2023076281A1 (en) 2021-10-25 2023-05-04 Aquestive Therapeutics, Inc. Oral and nasal compositions and methods of treatment

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3742951A (en) * 1971-08-09 1973-07-03 Alza Corp Bandage for controlled release of vasodilators
US3896789A (en) * 1974-06-10 1975-07-29 Riker Laboratories Inc Retinoic acid dipensing pressure sensitive dermotological tape
US4310509A (en) * 1979-07-31 1982-01-12 Minnesota Mining And Manufacturing Company Pressure-sensitive adhesive having a broad spectrum antimicrobial therein
DE3005374A1 (de) * 1980-02-11 1981-08-20 Schering Ag Berlin Und Bergkamen, 1000 Berlin 3-desoxy-delta hoch 15 -steroide, verfahren zu ihrer herstellung sowie diese enthaltende pharmazeutische praeparate
JPS56133381A (en) * 1980-03-25 1981-10-19 Nippon Kayaku Co Ltd Pressure-sensitive adhesive tape or sheet containing nitroglycerin
JPS577413A (en) * 1980-06-14 1982-01-14 Nitto Electric Ind Co Ltd Plaster
JPS577414A (en) * 1980-06-14 1982-01-14 Nitto Electric Ind Co Ltd Preparation of plaster
JPS577409A (en) * 1980-06-14 1982-01-14 Nitto Electric Ind Co Ltd Plaster
JPS5777617A (en) * 1980-10-20 1982-05-15 Nichiban Co Ltd Plaster for cardiac disease
IL61721A (en) * 1980-12-16 1984-03-30 Blank Izhak Nitroglycerin preparations
JPS6059207B2 (ja) * 1981-03-13 1985-12-24 日東電工株式会社 複合製剤の製法
GB2105990B (en) * 1981-08-27 1985-06-19 Nitto Electric Ind Co Adhesive skin patches
JPS6038368B2 (ja) * 1981-09-12 1985-08-31 日東電工株式会社 貼付剤の製造方法
US4374164A (en) * 1981-12-14 1983-02-15 American Cyanamid Company High solids polymer resin coating composition containing amino resin cross-linking agent
US4608249A (en) * 1982-11-02 1986-08-26 Nitto Electric Industrial Co., Ltd. Hydrophilic therapeutic material

Also Published As

Publication number Publication date
NO171950C (no) 1993-05-26
FI861177A7 (fi) 1986-03-20
FI861177A0 (fi) 1986-03-20
JPH0440326B2 (enExample) 1992-07-02
EP0190262A1 (en) 1986-08-13
WO1986000814A1 (en) 1986-02-13
HK94093A (en) 1993-09-17
AU576889B2 (en) 1988-09-08
NO171950B (no) 1993-02-15
EP0190262B1 (en) 1990-12-27
US5186938A (en) 1993-02-16
MY100249A (en) 1990-07-12
FI85106B (fi) 1991-11-29
NO861101L (no) 1986-03-20
ATE59302T1 (de) 1991-01-15
AU4676185A (en) 1986-02-25
JPS61502760A (ja) 1986-11-27
FI85106C (fi) 1992-03-10

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