DE3578613D1 - Verfahren zur reinigung des influenzavirus. - Google Patents

Verfahren zur reinigung des influenzavirus.

Info

Publication number
DE3578613D1
DE3578613D1 DE8585110012T DE3578613T DE3578613D1 DE 3578613 D1 DE3578613 D1 DE 3578613D1 DE 8585110012 T DE8585110012 T DE 8585110012T DE 3578613 T DE3578613 T DE 3578613T DE 3578613 D1 DE3578613 D1 DE 3578613D1
Authority
DE
Germany
Prior art keywords
influenza virus
cleaning
influence virus
virus
chromatography
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8585110012T
Other languages
German (de)
English (en)
Inventor
Tetsuya Oka
Kunio Ohkuma
Tetsuo Kawahara
Mitsuo Sakoh
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chemo Sero Therapeutic Research Institute Kaketsuken
Original Assignee
Chemo Sero Therapeutic Research Institute Kaketsuken
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chemo Sero Therapeutic Research Institute Kaketsuken filed Critical Chemo Sero Therapeutic Research Institute Kaketsuken
Application granted granted Critical
Publication of DE3578613D1 publication Critical patent/DE3578613D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/145—Orthomyxoviridae, e.g. influenza virus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
    • C12N2760/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
    • C12N2760/16151—Methods of production or purification of viral material

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Pulmonology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Detergent Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE8585110012T 1984-08-09 1985-08-08 Verfahren zur reinigung des influenzavirus. Expired - Lifetime DE3578613D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP59167324A JPS6147186A (ja) 1984-08-09 1984-08-09 インフルエンザウイルスの精製方法

Publications (1)

Publication Number Publication Date
DE3578613D1 true DE3578613D1 (de) 1990-08-16

Family

ID=15847633

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8585110012T Expired - Lifetime DE3578613D1 (de) 1984-08-09 1985-08-08 Verfahren zur reinigung des influenzavirus.

Country Status (7)

Country Link
US (1) US4724210A (cg-RX-API-DMAC10.html)
EP (1) EP0171086B1 (cg-RX-API-DMAC10.html)
JP (1) JPS6147186A (cg-RX-API-DMAC10.html)
KR (1) KR920009733B1 (cg-RX-API-DMAC10.html)
AT (1) ATE54468T1 (cg-RX-API-DMAC10.html)
CA (1) CA1251399A (cg-RX-API-DMAC10.html)
DE (1) DE3578613D1 (cg-RX-API-DMAC10.html)

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US5215739A (en) * 1989-04-05 1993-06-01 Toko Yakuhin Kogyo Kabushiki Kaisha Spray gel base and spray gel preparation using thereof
US5158761A (en) * 1989-04-05 1992-10-27 Toko Yakuhin Kogyo Kabushiki Kaisha Spray gel base and spray gel preparation using thereof
FR2667622B1 (fr) * 1990-10-08 1994-10-07 Kaysersberg Sa Montisse lie hydrauliquement et son procede de fabrication.
IT1248075B (it) * 1991-06-18 1995-01-05 Sclavo Spa Processo per la purificazione del virus dell'epatite a (hav), virus cosi` purificato e composizioni vaccinali che lo contengono.
US5447859A (en) * 1993-07-16 1995-09-05 Viagene Method for the purification or removal of retroviruses using sulfated cellulose
EP1010981A1 (de) * 1998-12-18 2000-06-21 Diagor GmbH Konjugate zum Nachweis von Viren und deren Verwendung
JP2002142770A (ja) 2000-11-08 2002-05-21 Dnavec Research Inc 循環系への遺伝子送達用パラミクソウイルスベクター
PL354822A1 (en) * 2002-06-30 2004-01-12 Instytut Immunologii i Terapii Doświadczalnej PANwe Wrocławiu Method of receiving purified bacteriophage preparations and new applications of polysaccharide or its esterificated derivative
CN1816619A (zh) * 2003-06-18 2006-08-09 昂尼克斯药物公司 纯化病毒的方法
AU2004249802B2 (en) * 2003-06-20 2007-06-28 Microbix Biosystems Inc. Improvements in virus production
WO2005042737A1 (ja) 2003-11-04 2005-05-12 Dnavec Research Inc. 遺伝子導入された樹状細胞の製造方法
AU2006258655A1 (en) 2005-06-14 2006-12-21 Dnavec Corporation Method for production of antibody
US8877187B2 (en) * 2005-07-25 2014-11-04 Avianax, Llc Therapeutic antibodies for treatment and prophylaxis of transmittable viral diseases
AU2006285306B2 (en) * 2005-07-25 2012-07-19 Avianax, Llc. Therapeutic antibodies for treatment and prophylaxis of transmittable viral diseases
EP1808697A1 (en) * 2006-01-13 2007-07-18 Novartis Vaccines and Diagnostics, Inc. Use of an ion exchange matrix for determining the concentration of virus particles and/or virus antigens
CN101405389A (zh) 2006-01-17 2009-04-08 生物载体株式会社 新型蛋白质表达系统
US20100297604A1 (en) * 2006-06-09 2010-11-25 Xing-Xiang Li Methods and reagents for virus isolation and detection
EP1878791A1 (en) * 2006-07-11 2008-01-16 Bia Separations D.O.O. Method for influenza virus purification
US20100209974A1 (en) 2006-07-13 2010-08-19 Dnavec Corporation Non-replicating paramyxoviridae virus vector
WO2008039136A1 (en) * 2006-09-29 2008-04-03 Ge Healthcare Bio-Sciences Ab Separation matrix for viral purification
EP1982727A1 (en) 2007-04-17 2008-10-22 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Method for purification of viral proteins
US20100203027A1 (en) 2007-04-27 2010-08-12 Kyushu Univeristy National University Viral vector for gene therapy
CA2692149A1 (en) * 2007-06-29 2009-01-08 Avianax, Llc Vaccine production for pathogenic bird viral diseases
JP5389342B2 (ja) * 2007-08-09 2014-01-15 デンカ生研株式会社 吸着担体及び吸着担体の製造方法
JP5716297B2 (ja) 2009-06-25 2015-05-13 Jnc株式会社 クロマトグラフィー用充填剤、その製造方法、およびそれを用いたウイルス用ワクチンの製造方法
CN102985536B (zh) 2010-04-14 2017-12-05 Emd密理博公司 生产高效价、高纯度的病毒母液的方法及使用其的方法
CN104968403A (zh) 2012-09-17 2015-10-07 格雷斯公司 色谱介质和装置
JP6369467B2 (ja) * 2013-09-02 2018-08-08 Jnc株式会社 多孔性セルロース粒子の製造方法および多孔性セルロース粒子
DE102013017014B4 (de) 2013-10-14 2017-03-30 Sartorius Stedim Biotech Gmbh Sulfatierte Cellulosehydrat-Membran, Verfahren zur ihrer Herstellung und Verwendung der Membran als Adsorptionsmembran für die Virenaufreinigung
ES2929099T3 (es) 2014-05-02 2022-11-24 Grace W R & Co Material de soporte funcionalizado y métodos de fabricación y uso de material de soporte funcionalizado
EP2966093A1 (en) * 2014-07-07 2016-01-13 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Process for the preparation of magnetic sulfated cellulose particles, magnetic sulfated cellulose particles and their use
JP2018517559A (ja) 2015-06-05 2018-07-05 ダブリュー・アール・グレース・アンド・カンパニー−コーンＷ Ｒ Ｇｒａｃｅ ＆ Ｃｏ−Ｃｏｎｎ 吸着性バイオプロセス清澄化剤並びにその製造及び使用方法
US10626376B2 (en) 2016-11-14 2020-04-21 St. Jude Children's Research Hospital Method for isolating and purifying adeno-associated virus particles using salt
CN106622159B (zh) * 2016-12-22 2019-06-14 苏州楚博生物技术有限公司 用于蛋白药物纯化的亲和层析介质

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL131092C (cg-RX-API-DMAC10.html) *
US3105012A (en) * 1961-10-19 1963-09-24 Parke Davis & Co Antigen products and means for producing the same
BE662899A (cg-RX-API-DMAC10.html) * 1964-04-22
US3547779A (en) * 1968-12-18 1970-12-15 Merck & Co Inc Process for producing purified concentrated influenza virus
SE356735B (cg-RX-API-DMAC10.html) * 1970-12-02 1973-06-04 Svenska Cellulosa Ab
US3842062A (en) * 1972-09-27 1974-10-15 Du Pont Water-soluble complexes of protein and anionic polyelectrolytes such as sodium carboxymethyl cellulose
US3920625A (en) * 1973-06-19 1975-11-18 Kabi Ab Isolation of coagulation factors from biological material using cross linked sulfated, sulfonated carbohydrates
US4160019A (en) * 1973-06-25 1979-07-03 Bjorklund Knut B Detection of cancer associated polypeptide antigen and preparation of antibodies thereto
IL49752A (en) * 1975-07-09 1979-07-25 Kabi Ab Compositions having affinity for hepatitis virus and method for hepatitis virus removal or concentration
SE420977B (sv) * 1976-03-18 1981-11-16 Kabi Ab Forfarande for rening och isolering av hepatitvirus for vaccinframstellning
US4181713A (en) * 1978-10-30 1980-01-01 Merck & Co., Inc. Isolation of HBs Ag
DE3014189A1 (de) * 1980-04-14 1981-10-15 Europäisches Laboratorium für Molekularbiologie (EMBL), 6900 Heidelberg Verfahren zur herstellung eines immunogenen membranproteinaggregats von influenza-, parainfluenza- und rhabdo-viren
JPS57136528A (en) * 1981-02-09 1982-08-23 Hayashibara Biochem Lab Inc Preparation of viral vaccine
US4434093A (en) * 1982-07-26 1984-02-28 Ortho Diagnostic Systems Inc. Methods for preparation of HBs Ag free gamma globulins
US4515714A (en) * 1983-03-09 1985-05-07 Juridicial Foundation, The Chemo-Semo-Sero-Therapeutic Research Institute Method for purification of hepatitis B virus surface antigen

Also Published As

Publication number Publication date
EP0171086A3 (en) 1988-01-13
CA1251399A (en) 1989-03-21
EP0171086B1 (en) 1990-07-11
JPS6230752B2 (cg-RX-API-DMAC10.html) 1987-07-03
KR920009733B1 (ko) 1992-10-22
KR870001835A (ko) 1987-03-28
JPS6147186A (ja) 1986-03-07
US4724210A (en) 1988-02-09
ATE54468T1 (de) 1990-07-15
EP0171086A2 (en) 1986-02-12

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Legal Events

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