DK154760C - Fremgangsmaade til fremstilling af acemetacin - Google Patents

Fremgangsmaade til fremstilling af acemetacin

Info

Publication number
DK154760C
DK154760C DK570282A DK570282A DK154760C DK 154760 C DK154760 C DK 154760C DK 570282 A DK570282 A DK 570282A DK 570282 A DK570282 A DK 570282A DK 154760 C DK154760 C DK 154760C
Authority
DK
Denmark
Prior art keywords
acemetacin
procedure
preparation
chlorobenzoyl
indole
Prior art date
Application number
DK570282A
Other languages
English (en)
Other versions
DK570282A (da
DK154760B (da
Inventor
Rene Gnehm
Rolf Weber
Original Assignee
Siegfried Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Siegfried Ag filed Critical Siegfried Ag
Publication of DK570282A publication Critical patent/DK570282A/da
Publication of DK154760B publication Critical patent/DK154760B/da
Application granted granted Critical
Publication of DK154760C publication Critical patent/DK154760C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/26—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an acyl radical attached to the ring nitrogen atom
    • C07D209/28—1-(4-Chlorobenzoyl)-2-methyl-indolyl-3-acetic acid, substituted in position 5 by an oxygen or nitrogen atom; Esters thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pyrane Compounds (AREA)
  • Cephalosporin Compounds (AREA)
DK570282A 1981-12-28 1982-12-23 Fremgangsmaade til fremstilling af acemetacin DK154760C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH830681 1981-12-28
CH8306/81A CH653326A5 (de) 1981-12-28 1981-12-28 Verfahren zur herstellung eines indolderivates.

Publications (3)

Publication Number Publication Date
DK570282A DK570282A (da) 1983-06-29
DK154760B DK154760B (da) 1988-12-19
DK154760C true DK154760C (da) 1989-06-05

Family

ID=4338290

Family Applications (1)

Application Number Title Priority Date Filing Date
DK570282A DK154760C (da) 1981-12-28 1982-12-23 Fremgangsmaade til fremstilling af acemetacin

Country Status (9)

Country Link
US (2) US4503237A (da)
EP (1) EP0084127B1 (da)
JP (1) JPS58118568A (da)
AT (1) ATE18905T1 (da)
CH (1) CH653326A5 (da)
DE (1) DE3270313D1 (da)
DK (1) DK154760C (da)
ES (1) ES8401939A1 (da)
FI (1) FI77445C (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH653326A5 (de) * 1981-12-28 1985-12-31 Siegfried Ag Verfahren zur herstellung eines indolderivates.
DE3206885A1 (de) * 1982-02-26 1983-09-15 Troponwerke GmbH & Co KG, 5000 Köln Indolderivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
JPS59204172A (ja) * 1983-04-28 1984-11-19 Kowa Co アセメタシンの製造法
DE3416895A1 (de) * 1984-05-08 1985-11-14 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von acemetacin
DE3443993A1 (de) * 1984-12-01 1986-06-05 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von neuen indolderivaten und deren verwendung

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA837084A (en) * 1970-03-17 Sletzinger Meyer Method for preparing indolylacetic acid esters
DE2234651C3 (de) * 1972-07-14 1978-11-09 Troponwerke Gmbh & Co Kg, 5000 Koeln Eckige Klammer auf l-(p-Chlorbenzoyl)-5-methoxy-2-methyl-3-indol] -acetoxj essigsaure, ihre Salze mit Basen, Verfahren zu ihrer Herstellung sowie pharmakologische Zubereitungen
DE2943125A1 (de) * 1979-10-25 1981-05-14 Troponwerke GmbH & Co KG, 5000 Köln Verfahren zur herstellung von 1-(4-chlorbenzoyl)-5-methoxy-2-methyl-3-indol acetoxyessigsaeure
CH653326A5 (de) * 1981-12-28 1985-12-31 Siegfried Ag Verfahren zur herstellung eines indolderivates.
JPS59204172A (ja) * 1983-04-28 1984-11-19 Kowa Co アセメタシンの製造法

Also Published As

Publication number Publication date
ATE18905T1 (de) 1986-04-15
CH653326A5 (de) 1985-12-31
JPS58118568A (ja) 1983-07-14
DE3270313D1 (en) 1986-05-07
FI77445B (fi) 1988-11-30
ES518419A0 (es) 1984-01-16
US4503237A (en) 1985-03-05
FI824420L (fi) 1983-06-29
EP0084127A1 (de) 1983-07-27
DK570282A (da) 1983-06-29
JPH0222747B2 (da) 1990-05-21
FI77445C (fi) 1989-03-10
EP0084127B1 (de) 1986-04-02
ES8401939A1 (es) 1984-01-16
DK154760B (da) 1988-12-19
FI824420A0 (fi) 1982-12-22
US4652659A (en) 1987-03-24

Similar Documents

Publication Publication Date Title
EP0171086A3 (en) A method for purification of influenza virus
ES490132A0 (es) Procedimiento de produccion de derivados de acido acetico.
DE2960652D1 (en) Process for the stereoselective synthesis of sexual pheromones and the pheromones so obtained
DK154760C (da) Fremgangsmaade til fremstilling af acemetacin
GB2006248A (en) Preparation of chromogenic pyridine compounds
NO822127L (no) Fremgangsmaate for fremstilling av estere av 3-metylflavon-8-karboksylsyre.
YU60778A (en) Process for the enzymatic hydrolysis of racemic hydantoin into optically active amino-acids
SE8301997L (sv) Framstellning av 6,11-dihydro-11-oxodibens(b,e)-oxepin-2-ettiksyra
ES2001695A6 (es) Procedimiento para preparar esteres alquilicos de c1-c4 de acido 4-alcoxi-3-pirrolin-2-on-1-il-acetico
FR2483948B1 (fr) Production de l-proline par fermentation
FI862719A0 (fi) Foerfarande foer framstaellning av meldrum-syra.
DE3361013D1 (en) A novel ester of the 1-methyl-5-p-toluoylpyrrolyl-2-acetic acid having antiinflammatory, mucolytic and antitussive properties, process for its preparation and pharmaceutical compositions containing them
BE888336A (nl) Werkwijze ter bereinding van cyclopropaan-carbonzure esterderivaten,
NO792126L (no) Karbazolderivater.
IT8421922A1 (it) Procedimento per produrre l-aminoacidi da alfa-chetoacidi mediante fermentazione
FR2552761B1 (fr) Procede de transformation directe d'un aldehyde en un ester ethylenique, nouvelles molecules synthetisees
SE8001617L (sv) Forfarande for framstellning av ett karbazolderivat
MX5647E (es) Procedimiento de fermentacion para la produccion de polisacaridos
ES8506257A1 (es) Un procedimiento de preparar un nuevo ester de un acido acetico sustituido
IT7830163A0 (it) Sostituiti. procedimento per la fabbricazione di esteri basici di acidi idrossicicicloesancarbossilici
DE3363336D1 (en) Process for the preparation of 1-(4-chlorbenzoyl)-5-methoxy-2-methyl-3-indolylacetoxy-acetic acid
IT8248027A0 (it) Razione e loro applicazione alla esteri di acidi ciclopropancarbossi lotta antiparassitaria lici aventi un sostituente polialogenato, loro procedimento di prepa-
DE3363239D1 (en) Process for the preparation of 1-(4-chlorbenzoyl)-5-methoxy-2-methyl-3-indolylacetoxy-acetic acid
ES8207140A1 (es) Un procedimiento para preparar esteres de pirrol .
FR2429773A1 (fr) Nouveau derive de l'acide acetylsalicylique, procede d'obtention de celui-ci et composition pharmaceutique en comportant application

Legal Events

Date Code Title Description
PBP Patent lapsed