DE3576362D1 - Verfahren zur reinigung einer physiologisch aktiven substanz, die durch rekombinante dna-technik hergestellt wurde. - Google Patents

Verfahren zur reinigung einer physiologisch aktiven substanz, die durch rekombinante dna-technik hergestellt wurde.

Info

Publication number
DE3576362D1
DE3576362D1 DE8585114806T DE3576362T DE3576362D1 DE 3576362 D1 DE3576362 D1 DE 3576362D1 DE 8585114806 T DE8585114806 T DE 8585114806T DE 3576362 T DE3576362 T DE 3576362T DE 3576362 D1 DE3576362 D1 DE 3576362D1
Authority
DE
Germany
Prior art keywords
active substance
recombinant dna
physiologically active
purifying
dna technology
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8585114806T
Other languages
English (en)
Inventor
Junichi Kajihara
Takao Kiyota
Hiroshi Hayashi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Asahi Kasei Corp
Asahi Chemical Industry Co Ltd
Original Assignee
Asahi Chemical Industry Co Ltd
Asahi Kasei Kogyo KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asahi Chemical Industry Co Ltd, Asahi Kasei Kogyo KK filed Critical Asahi Chemical Industry Co Ltd
Application granted granted Critical
Publication of DE3576362D1 publication Critical patent/DE3576362D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/525—Tumour necrosis factor [TNF]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y10S530/828—Cancer

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Wood Science & Technology (AREA)
  • Toxicology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE8585114806T 1984-11-22 1985-11-21 Verfahren zur reinigung einer physiologisch aktiven substanz, die durch rekombinante dna-technik hergestellt wurde. Expired - Lifetime DE3576362D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP59246184A JPS61124392A (ja) 1984-11-22 1984-11-22 遺伝子組換体の産生する生理活性物質の精製法

Publications (1)

Publication Number Publication Date
DE3576362D1 true DE3576362D1 (de) 1990-04-12

Family

ID=17144758

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8585114806T Expired - Lifetime DE3576362D1 (de) 1984-11-22 1985-11-21 Verfahren zur reinigung einer physiologisch aktiven substanz, die durch rekombinante dna-technik hergestellt wurde.

Country Status (11)

Country Link
US (1) US4880915A (de)
EP (1) EP0183198B1 (de)
JP (1) JPS61124392A (de)
KR (1) KR940000542B1 (de)
AT (1) ATE50794T1 (de)
AU (1) AU591879B2 (de)
CA (1) CA1265650A (de)
DD (1) DD240216A5 (de)
DE (1) DE3576362D1 (de)
IL (1) IL77101A (de)
SU (1) SU1630602A3 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5288852A (en) * 1984-03-06 1994-02-22 Dainippon Pharmaceutical Co., Ltd. Human tumor necrosis factor polypeptides
DE19975063I2 (de) * 1984-03-06 2005-08-18 Dainippon Pharmaceutical Co DNS den menschlichen Tumornekrosisfaktor kodierendund das menschliche Tumornekronisfaktor-Polypepti d.
US4879226A (en) * 1984-04-06 1989-11-07 Asahi Kasei Kogyo Kabushiki Kaisha Novel human physiologically active polypeptide
US6686455B1 (en) * 1984-07-05 2004-02-03 Genentech, Inc. Tumor necrosis factor
IL73883A (en) * 1984-12-20 1990-12-23 Yeda Res & Dev Monoclonal antibodies against tnf-alpha,hybridomas producing them and method for the purification of tnf-alpha
DE3585690D1 (de) * 1984-12-21 1992-04-23 Biogen Inc Reinigung, herstellung und verwendung von tumor-nekrosisfaktoren.
JPS61155330A (ja) * 1984-12-28 1986-07-15 Denichi Mizuno 蛋白質標品
US4870163A (en) * 1985-08-29 1989-09-26 New York Blood Center, Inc. Preparation of pure human tumor necrosis factor and hybridomas producing monoclonal antibodies to human tumor necrosis factor
US4777242A (en) * 1986-10-10 1988-10-11 Phillips Petroleum Company Purification of recombinant tumor necrosis factor
EP0299746B1 (de) * 1987-07-16 1992-08-26 Schering Corporation Reinigung von GM-CSF
US5391706A (en) * 1987-07-16 1995-02-21 Schering Plough Corporation Purification of GM-CSF
US5597485A (en) * 1988-05-13 1997-01-28 Vilmax S.A. Process for separating proteins
DE4331358A1 (de) * 1992-10-12 1994-04-14 Braun Melsungen Ag Verfahren zur quantitativen selektiven Entfernung oder präparativen Gewinnung von Tumor-Nekrose-Faktor (TNF) oder/und Lipopolysacchariden (LPS) aus wäßrigen Flüssigkeiten
DE19549420A1 (de) * 1995-04-27 1997-09-18 Braun Melsungen Ag Verfahren zur simultanen extrakorporalen Elimination von Tumor-Nekrose Faktor alpha (TNF alpha) und bakteriellen Lipopolysacchariden (LPS) aus Vollblut oder/und Blutplasma
EP1373868B1 (de) * 2001-02-01 2015-05-20 Sigma-Aldrich Co. LLC Verbesserte affinitätsmatrizen mit grösserer sichtbarkeit für molekulare absenkung und immunoniederschlag anwendungen
AU2003298816C1 (en) 2002-12-02 2010-12-16 Amgen Fremont, Inc. Antibodies directed to Tumor Necrosis Factor and uses thereof
US20050287515A1 (en) * 2004-06-24 2005-12-29 Reinhold Deppisch Removal of bacterial DNA from therapeutic fluid formulations
JP7044753B2 (ja) 2016-03-17 2022-03-30 パーキンエルマー・ヘルス・サイエンシーズ・ベスローテン・フェンノートシャップ 液体サンプル中の細胞の検出

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4879226A (en) * 1984-04-06 1989-11-07 Asahi Kasei Kogyo Kabushiki Kaisha Novel human physiologically active polypeptide
US4677064A (en) * 1984-11-09 1987-06-30 Cetus Corporation Human tumor necrosis factor
US4677063A (en) * 1985-05-02 1987-06-30 Cetus Corporation Human tumor necrosis factor
US4770995A (en) * 1985-08-29 1988-09-13 New York Blood Center, Inc Detection of the sensitivity of cells to the effects of tumor necrosis factor and lymphotoxin
US4677197A (en) * 1985-10-30 1987-06-30 Cetus Corporation Purification method for tumor necrosis factor

Also Published As

Publication number Publication date
JPS61124392A (ja) 1986-06-12
AU5024885A (en) 1986-05-29
DD240216A5 (de) 1986-10-22
US4880915A (en) 1989-11-14
AU591879B2 (en) 1989-12-21
ATE50794T1 (de) 1990-03-15
EP0183198B1 (de) 1990-03-07
SU1630602A3 (ru) 1991-02-23
EP0183198A1 (de) 1986-06-04
CA1265650A (en) 1990-02-06
KR940000542B1 (ko) 1994-01-24
KR860004149A (ko) 1986-06-18
JPH0229317B2 (de) 1990-06-28
IL77101A (en) 1991-01-31

Similar Documents

Publication Publication Date Title
DE3576362D1 (de) Verfahren zur reinigung einer physiologisch aktiven substanz, die durch rekombinante dna-technik hergestellt wurde.
IT7867133A0 (it) Procedimento per la purificazione di acque di rifiuto ricche in carboidrati e la produzione simultanea di mangimi ad alto contenuto in proteine
PT83958B (pt) Processo de preparacao de mono-hidrato do hidrocloreto de n,n-dimetil-1-{1-(4-clorofenil)ciclobutil}-3-metilbutilamina
FR2603581B1 (fr) Procede pour isoler et purifier des aminoacides par chromatographie
DK0813541T3 (da) Fremgangsmåde til fremstilling af et protein
DE3680130D1 (de) Verfahren zur vireninaktivierung in gamma-globulin durch waermebehandlung.
DE3874619D1 (de) Herstellungsverfahren eines optisch aktiven alkohols.
DE3578839D1 (de) Verfahren zur reinigung des japanischen enzephalitisvirus.
ES2070855T3 (es) Metodo para purificar una proteina.
NZ224295A (en) A method of producing native or physiologically active secondary structure in physiologically inactive proteins
IT8621131A0 (it) Procedimento di idrogenazione di olefine in presenza di eteri.
FR2611205B1 (fr) Dipeptides, procede de preparation et utilisation dans le dosage de proteases
KR860008270A (ko) α-인터페론의 제조 및 정제 방법
FR2580667B1 (fr) Procede de preparation enzymatique de l-amino acides renfermant du soufre
KR890006556A (ko) 메타크릴산의 정제방법
DK121082A (da) 3-alken-1-yl-2,2-dimethyl-cyclopropancarboxylsyre-(4-fluor-3-phenoxy-benzyl)-estere,fremgangsmaade til deres fremstilling og deres anvendelse i skadedyrsbekaempelsesmidler
DE3376847D1 (en) Capillary filter consisting of semipermeable membrane with enzymatic activity, process for its manufacture and its applications
HUT34051A (en) Process for contuonisly ensimatic transformation of alfa hydroxicarbonacids to suitable, optically active alpha aminocarbonacids
GB2126920B (en) Liquid active substance-containing membrane and process for its production
GB2169510B (en) Method of treatment of viral diseases in plants utilizing ribavirin
IS3292A7 (is) Gerjunaraðferð til að vernda fóður
FR2567125B1 (fr) Acides dihydro-5,6-4h-cyclopenta (b) thiophenecarboxylique-6, procedes de preparation et medicaments les contenant
IT1173502B (it) Procedimento per la purificazione di soluzioni contenenti fruttosio 2-6 difosfato (f-2,6-p2) e utilizzazione del composto cosi' ottenuto in terapia
RO83665A2 (ro) Compozitie catalitica folosita la obtinerea acizilor nesaturati
FR2527630B1 (fr) Enzyme leucocytaire humaine de type pepsique, procede pour sa preparation et agent therapeutique la contenant

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee