ATE50794T1 - Verfahren zur reinigung einer physiologisch aktiven substanz, die durch rekombinante dnatechnik hergestellt wurde. - Google Patents
Verfahren zur reinigung einer physiologisch aktiven substanz, die durch rekombinante dnatechnik hergestellt wurde.Info
- Publication number
- ATE50794T1 ATE50794T1 AT85114806T AT85114806T ATE50794T1 AT E50794 T1 ATE50794 T1 AT E50794T1 AT 85114806 T AT85114806 T AT 85114806T AT 85114806 T AT85114806 T AT 85114806T AT E50794 T1 ATE50794 T1 AT E50794T1
- Authority
- AT
- Austria
- Prior art keywords
- active substance
- recombinant dna
- physiologically active
- purification
- dna technology
- Prior art date
Links
- 108020004511 Recombinant DNA Proteins 0.000 title abstract 2
- 239000013543 active substance Substances 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 238000000746 purification Methods 0.000 title 1
- 238000011725 BALB/c mouse Methods 0.000 abstract 1
- 206010039491 Sarcoma Diseases 0.000 abstract 1
- 239000011543 agarose gel Substances 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 238000004440 column chromatography Methods 0.000 abstract 1
- 230000001472 cytotoxic effect Effects 0.000 abstract 1
- 230000002008 hemorrhagic effect Effects 0.000 abstract 1
- 230000001939 inductive effect Effects 0.000 abstract 1
- 230000017074 necrotic cell death Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/525—Tumour necrosis factor [TNF]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/827—Proteins from mammals or birds
- Y10S530/828—Cancer
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Engineering & Computer Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Wood Science & Technology (AREA)
- Toxicology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP59246184A JPS61124392A (ja) | 1984-11-22 | 1984-11-22 | 遺伝子組換体の産生する生理活性物質の精製法 |
| EP85114806A EP0183198B1 (de) | 1984-11-22 | 1985-11-21 | Verfahren zur Reinigung einer physiologisch aktiven Substanz, die durch rekombinante DNA-Technik hergestellt wurde |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE50794T1 true ATE50794T1 (de) | 1990-03-15 |
Family
ID=17144758
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT85114806T ATE50794T1 (de) | 1984-11-22 | 1985-11-21 | Verfahren zur reinigung einer physiologisch aktiven substanz, die durch rekombinante dnatechnik hergestellt wurde. |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US4880915A (de) |
| EP (1) | EP0183198B1 (de) |
| JP (1) | JPS61124392A (de) |
| KR (1) | KR940000542B1 (de) |
| AT (1) | ATE50794T1 (de) |
| AU (1) | AU591879B2 (de) |
| CA (1) | CA1265650A (de) |
| DD (1) | DD240216A5 (de) |
| DE (1) | DE3576362D1 (de) |
| IL (1) | IL77101A (de) |
| SU (1) | SU1630602A3 (de) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5288852A (en) * | 1984-03-06 | 1994-02-22 | Dainippon Pharmaceutical Co., Ltd. | Human tumor necrosis factor polypeptides |
| DE3582183D1 (de) * | 1984-03-06 | 1991-04-25 | Dainippon Pharmaceutical Co | Dns den menschlichen tumornekrosisfaktor kodierend und das menschliche tumornekronisfaktor-polypeptid. |
| US4879226A (en) * | 1984-04-06 | 1989-11-07 | Asahi Kasei Kogyo Kabushiki Kaisha | Novel human physiologically active polypeptide |
| US6686455B1 (en) * | 1984-07-05 | 2004-02-03 | Genentech, Inc. | Tumor necrosis factor |
| IL73883A (en) * | 1984-12-20 | 1990-12-23 | Yeda Res & Dev | Monoclonal antibodies against tnf-alpha,hybridomas producing them and method for the purification of tnf-alpha |
| ATE73856T1 (de) * | 1984-12-21 | 1992-04-15 | Biogen Inc | Reinigung, herstellung und verwendung von tumor- nekrosisfaktoren. |
| JPS61155330A (ja) * | 1984-12-28 | 1986-07-15 | Denichi Mizuno | 蛋白質標品 |
| US4870163A (en) * | 1985-08-29 | 1989-09-26 | New York Blood Center, Inc. | Preparation of pure human tumor necrosis factor and hybridomas producing monoclonal antibodies to human tumor necrosis factor |
| US4777242A (en) * | 1986-10-10 | 1988-10-11 | Phillips Petroleum Company | Purification of recombinant tumor necrosis factor |
| WO1989000579A1 (en) * | 1987-07-16 | 1989-01-26 | Schering Corporation | Purification of gm-csf |
| US5391706A (en) * | 1987-07-16 | 1995-02-21 | Schering Plough Corporation | Purification of GM-CSF |
| US5597485A (en) * | 1988-05-13 | 1997-01-28 | Vilmax S.A. | Process for separating proteins |
| DE4331358A1 (de) * | 1992-10-12 | 1994-04-14 | Braun Melsungen Ag | Verfahren zur quantitativen selektiven Entfernung oder präparativen Gewinnung von Tumor-Nekrose-Faktor (TNF) oder/und Lipopolysacchariden (LPS) aus wäßrigen Flüssigkeiten |
| DE19549420A1 (de) * | 1995-04-27 | 1997-09-18 | Braun Melsungen Ag | Verfahren zur simultanen extrakorporalen Elimination von Tumor-Nekrose Faktor alpha (TNF alpha) und bakteriellen Lipopolysacchariden (LPS) aus Vollblut oder/und Blutplasma |
| US6887377B2 (en) * | 2001-02-01 | 2005-05-03 | Sigma-Aldrich Co. | Affinity matrices with enhanced visibility for molecular pull-down and immunoprecipitation applications |
| MXPA05005921A (es) | 2002-12-02 | 2005-10-19 | Abgenix Inc | Anticuerpos dirigidos a factor de necrosis tumoral y sus usos. |
| US20050287515A1 (en) * | 2004-06-24 | 2005-12-29 | Reinhold Deppisch | Removal of bacterial DNA from therapeutic fluid formulations |
| EP3430160A1 (de) | 2016-03-17 | 2019-01-23 | Delta Instruments B.V. | Nachweis von zellen in einer flüssigen probe |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4879226A (en) * | 1984-04-06 | 1989-11-07 | Asahi Kasei Kogyo Kabushiki Kaisha | Novel human physiologically active polypeptide |
| US4677064A (en) * | 1984-11-09 | 1987-06-30 | Cetus Corporation | Human tumor necrosis factor |
| US4677063A (en) * | 1985-05-02 | 1987-06-30 | Cetus Corporation | Human tumor necrosis factor |
| US4770995A (en) * | 1985-08-29 | 1988-09-13 | New York Blood Center, Inc | Detection of the sensitivity of cells to the effects of tumor necrosis factor and lymphotoxin |
| US4677197A (en) * | 1985-10-30 | 1987-06-30 | Cetus Corporation | Purification method for tumor necrosis factor |
-
1984
- 1984-11-22 JP JP59246184A patent/JPS61124392A/ja active Granted
-
1985
- 1985-11-19 IL IL77101A patent/IL77101A/xx not_active IP Right Cessation
- 1985-11-19 US US06/799,509 patent/US4880915A/en not_active Expired - Fee Related
- 1985-11-20 CA CA000495773A patent/CA1265650A/en not_active Expired - Lifetime
- 1985-11-21 DD DD85283097A patent/DD240216A5/de not_active IP Right Cessation
- 1985-11-21 AT AT85114806T patent/ATE50794T1/de not_active IP Right Cessation
- 1985-11-21 EP EP85114806A patent/EP0183198B1/de not_active Expired - Lifetime
- 1985-11-21 DE DE8585114806T patent/DE3576362D1/de not_active Expired - Lifetime
- 1985-11-21 AU AU50248/85A patent/AU591879B2/en not_active Ceased
- 1985-11-22 KR KR1019850008752A patent/KR940000542B1/ko not_active Expired - Fee Related
- 1985-11-22 SU SU853985474A patent/SU1630602A3/ru active
Also Published As
| Publication number | Publication date |
|---|---|
| IL77101A (en) | 1991-01-31 |
| DE3576362D1 (de) | 1990-04-12 |
| US4880915A (en) | 1989-11-14 |
| EP0183198B1 (de) | 1990-03-07 |
| AU591879B2 (en) | 1989-12-21 |
| JPH0229317B2 (de) | 1990-06-28 |
| EP0183198A1 (de) | 1986-06-04 |
| DD240216A5 (de) | 1986-10-22 |
| KR940000542B1 (ko) | 1994-01-24 |
| CA1265650A (en) | 1990-02-06 |
| JPS61124392A (ja) | 1986-06-12 |
| KR860004149A (ko) | 1986-06-18 |
| AU5024885A (en) | 1986-05-29 |
| SU1630602A3 (ru) | 1991-02-23 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE50794T1 (de) | Verfahren zur reinigung einer physiologisch aktiven substanz, die durch rekombinante dnatechnik hergestellt wurde. | |
| IT7867133A0 (it) | Procedimento per la purificazione di acque di rifiuto ricche in carboidrati e la produzione simultanea di mangimi ad alto contenuto in proteine | |
| FI865030A0 (fi) | Menetelmä terapeuttisesti käyttökelpoisen N,N-dimetyyli-1-/1-(4-kloorifenyyli)-syklobutyyli/-3-metyylibutyyliamiinihydrokloridimonohydraatin valmistamiseksi | |
| SE9500778D0 (sv) | Process for producing a protein | |
| ITRM910788A1 (it) | Immunoglobuline purificate, procedimento per la loro purificazione e loro impiego per la preparazione di medicinali. | |
| ES8501635A1 (es) | Un procedimiento de fraccionamiento de plasma sanguineo | |
| MY103892A (en) | Interleukin-2 of high purity production and use | |
| FR2525212B1 (fr) | Procede de transformation catalytique d'alcanes en aldehydes insatures | |
| DE3874619D1 (de) | Herstellungsverfahren eines optisch aktiven alkohols. | |
| IT8520036A0 (it) | Processo per la preparazione biotecnologica di acidi alfa-arilalcanoici otticamente attivi. | |
| HUT54884A (en) | Process and composition for inducing fertilization of plants | |
| DE3578839D1 (de) | Verfahren zur reinigung des japanischen enzephalitisvirus. | |
| EP0208215A3 (en) | Purification of blood clotting factors and other blood proteins on non-carbohydrate sulfated matrices | |
| ATE9354T1 (de) | Die blutkoagulation aktivierende produkte und verfahren zu deren herstellung. | |
| DE3460575D1 (en) | Process to improve the activity of high molecular crosslinked polycarbonacids | |
| ES8900018A1 (es) | Procedimiento para la fabricacion de derivados aminoalcoholes peptidicos inhibidores de la renina y de las proteasas acidas | |
| FR2611205B1 (fr) | Dipeptides, procede de preparation et utilisation dans le dosage de proteases | |
| FR2580667B1 (fr) | Procede de preparation enzymatique de l-amino acides renfermant du soufre | |
| DE3467340D1 (en) | Process for purification of 1,2-unsaturated carboxylic acids and/or esters thereof | |
| GB2126920B (en) | Liquid active substance-containing membrane and process for its production | |
| UA13475A (uk) | СПОСІБ ОДЕРЖАННЯ 6-БЕНЗИЛОКСИЗАМІЩЕНИХ ІЗОПРОПІЛОВИХ ЕФІРІВ beta-КАРБОЛІН-3-КАРБОНОВОЇ КИСЛОТИ | |
| IS3292A7 (is) | Gerjunaraðferð til að vernda fóður | |
| IT1173502B (it) | Procedimento per la purificazione di soluzioni contenenti fruttosio 2-6 difosfato (f-2,6-p2) e utilizzazione del composto cosi' ottenuto in terapia | |
| ATE133421T1 (de) | Verfahren zur herstellung von rekombinantem humaninterferon-beta in reiner form | |
| FR2633614B1 (fr) | Procede de monohalogenation en (alpha) des groupements carbonyles des cetones |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |