DE3569538D1 - Novel antibiotics, process for their preparation and pharmaceutical compositions containing them - Google Patents

Novel antibiotics, process for their preparation and pharmaceutical compositions containing them

Info

Publication number
DE3569538D1
DE3569538D1 DE8585111531T DE3569538T DE3569538D1 DE 3569538 D1 DE3569538 D1 DE 3569538D1 DE 8585111531 T DE8585111531 T DE 8585111531T DE 3569538 T DE3569538 T DE 3569538T DE 3569538 D1 DE3569538 D1 DE 3569538D1
Authority
DE
Germany
Prior art keywords
preparation
pharmaceutical compositions
compositions containing
novel antibiotics
novel compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8585111531T
Other languages
English (en)
Inventor
Ann Camille Horan
Jerzy Golik
James Andrew Matson
Mahesh Gordhandas Patel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sharp and Dohme Corp
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Application granted granted Critical
Publication of DE3569538D1 publication Critical patent/DE3569538D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • C12P1/02—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using fungi
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/38—Nucleosides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/044—Pyrrole radicals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C12P19/58—Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical directly bound through only acyclic carbon atoms to a non-saccharide heterocyclic ring, e.g. bleomycin, phleomycin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Mycology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Compounds Of Unknown Constitution (AREA)
DE8585111531T 1984-09-17 1985-09-12 Novel antibiotics, process for their preparation and pharmaceutical compositions containing them Expired DE3569538D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/651,498 US4743594A (en) 1984-09-17 1984-09-17 Antibiotic, antitumor compounds and their use

Publications (1)

Publication Number Publication Date
DE3569538D1 true DE3569538D1 (en) 1989-05-24

Family

ID=24613073

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8585111531T Expired DE3569538D1 (en) 1984-09-17 1985-09-12 Novel antibiotics, process for their preparation and pharmaceutical compositions containing them

Country Status (18)

Country Link
US (1) US4743594A (de)
EP (1) EP0175284B1 (de)
JP (1) JPS61106592A (de)
KR (1) KR860002574A (de)
AT (1) ATE42305T1 (de)
AU (1) AU4741785A (de)
CA (1) CA1315230C (de)
DE (1) DE3569538D1 (de)
DK (1) DK415185A (de)
ES (1) ES8703931A1 (de)
FI (1) FI853506L (de)
GR (1) GR852224B (de)
HK (1) HK4992A (de)
HU (1) HU194315B (de)
NO (1) NO853567L (de)
PT (1) PT81118B (de)
YU (1) YU147385A (de)
ZA (1) ZA857003B (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3835842A1 (de) * 1988-10-21 1990-04-26 Goedecke Ag Indolocarbazol-derivate, verfahren zu deren herstellung und deren verwendung als arzneimittel
US5015578A (en) * 1989-03-23 1991-05-14 Bristol-Myers Squibb Company BMY-41950 antitumor antibiotic
ES2125976T3 (es) * 1992-03-20 1999-03-16 Wellcome Found Otros derivados de indol con accion antiviral.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5918035A (ja) * 1982-07-20 1984-01-30 Katsuyuki Taniguchi ダンプ車の荷箱の支点構造
US4487925A (en) * 1983-01-28 1984-12-11 Bristol-Myers Company Rebeccamycin and process for its preparation
US4524145A (en) * 1984-09-04 1985-06-18 Bristol-Myers Company 4'-Deschlororebeccamycin pharmaceutical composition and method of use

Also Published As

Publication number Publication date
ES546915A0 (es) 1987-03-01
EP0175284A3 (en) 1986-12-17
EP0175284A2 (de) 1986-03-26
EP0175284B1 (de) 1989-04-19
DK415185A (da) 1986-03-18
JPH0558440B2 (de) 1993-08-26
HU194315B (en) 1988-01-28
ES8703931A1 (es) 1987-03-01
JPS61106592A (ja) 1986-05-24
ATE42305T1 (de) 1989-05-15
CA1315230C (en) 1993-03-30
US4743594A (en) 1988-05-10
ZA857003B (en) 1986-12-30
PT81118B (en) 1987-07-06
HUT42527A (en) 1987-07-28
KR860002574A (ko) 1986-04-26
GR852224B (de) 1986-01-13
FI853506A0 (fi) 1985-09-13
FI853506L (fi) 1986-03-18
YU147385A (en) 1988-06-30
NO853567L (no) 1986-03-18
DK415185D0 (da) 1985-09-12
PT81118A (en) 1985-10-01
AU4741785A (en) 1986-04-24
HK4992A (en) 1992-01-17

Similar Documents

Publication Publication Date Title
AU2130983A (en) Epimeric azahomoerythromycin a derivatives
DE69631609D1 (en) Tricyclische erythromycinderivate
DE69317877D1 (en) 4''-deoxyerythromycinderivate
AU555208B2 (en) 4"-epi-erythromycin a
DE3466991D1 (en) Penems, pharmaceutical compositions containing them, and process for their preparation
DE3569538D1 (en) Novel antibiotics, process for their preparation and pharmaceutical compositions containing them
BG101163A (en) 8-fluoro-anthracyclines, processes for their preparation and pharmaceutical compositions containing them
AU7649391A (en) 3'-deamino-4'-deoxy-4'-amino-8-fluoroanthracyclines and processes for their preparation
PT77250B (en) Process for producing antimicrobial and antitumor antibiotic m 9026 and its pure individual factors 1,2 and 3,and of pharmaceutical compositions containing the same
AU578335B2 (en) N-substituted aziridine-2-carboxylic acid derivatives
HUT35694A (en) Process for producing 2'-deoxy-oxanosine and pharmaceutical compositions containing them
AU7993982A (en) Tetra-peptide

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee