DE3482322D1 - Bis-dioxopiperazin-derivate, verfahren zu ihrer herstellung, sie enthaltende antitumor-mittel und sie enthaltende zubereitungen. - Google Patents

Bis-dioxopiperazin-derivate, verfahren zu ihrer herstellung, sie enthaltende antitumor-mittel und sie enthaltende zubereitungen.

Info

Publication number
DE3482322D1
DE3482322D1 DE8484112763T DE3482322T DE3482322D1 DE 3482322 D1 DE3482322 D1 DE 3482322D1 DE 8484112763 T DE8484112763 T DE 8484112763T DE 3482322 T DE3482322 T DE 3482322T DE 3482322 D1 DE3482322 D1 DE 3482322D1
Authority
DE
Germany
Prior art keywords
antitumor
preparations
containers
bis
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8484112763T
Other languages
English (en)
Inventor
Jun-Chao C O Laboratory Of Cai
Muneaki Takase
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zenyaku Kogyo KK
Original Assignee
Zenyaku Kogyo KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zenyaku Kogyo KK filed Critical Zenyaku Kogyo KK
Application granted granted Critical
Publication of DE3482322D1 publication Critical patent/DE3482322D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/06—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members
    • C07D241/08—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE8484112763T 1983-10-31 1984-10-23 Bis-dioxopiperazin-derivate, verfahren zu ihrer herstellung, sie enthaltende antitumor-mittel und sie enthaltende zubereitungen. Expired - Fee Related DE3482322D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP58204448A JPS6097963A (ja) 1983-10-31 1983-10-31 ビス−ジオキソピペラジン誘導体，その製造方法及びそれからなる抗腫瘍剤

Publications (1)

Publication Number Publication Date
DE3482322D1 true DE3482322D1 (de) 1990-06-28

Family

ID=16490690

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8484112763T Expired - Fee Related DE3482322D1 (de) 1983-10-31 1984-10-23 Bis-dioxopiperazin-derivate, verfahren zu ihrer herstellung, sie enthaltende antitumor-mittel und sie enthaltende zubereitungen.

Country Status (9)

Country Link
US (1) US4650799A (de)
EP (1) EP0140327B1 (de)
JP (1) JPS6097963A (de)
AU (1) AU571273B2 (de)
CA (1) CA1244430A (de)
DE (1) DE3482322D1 (de)
DK (1) DK162639C (de)
ES (1) ES8507513A1 (de)
NO (1) NO170682C (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0674251B2 (ja) * 1986-02-07 1994-09-21 全薬工業株式▲会▼社 ビス−ジオキソピペラジン誘導体
WO1992000971A1 (en) * 1990-07-04 1992-01-23 Zenyaku Kogyo Kabushiki Kaisha Water-soluble bis-dioxopiperazine derivative
JP5732453B2 (ja) * 2009-06-25 2015-06-10 アルカーメス ファーマ アイルランド リミテッド Ｎｈ酸性化合物のプロドラッグ

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL273692A (de) * 1961-01-19 1900-01-01
GB1234935A (en) * 1967-07-03 1971-06-09 Nat Res Dev Piperazine derivatives
GB1236947A (en) * 1968-08-15 1971-06-23 Ici Ltd Process for the preparation of piperazine derivatives
DE2511891A1 (de) * 1975-03-19 1976-10-07 Gruenenthal Chemie Neue derivate des 2,6-dioxopiperazins, verfahren zu ihrer herstellung, diese verbindungen enthaltende arzneimittel sowie verfahren zu deren herstellung
CH635828A5 (de) * 1978-08-30 1983-04-29 Ciba Geigy Ag N-substituierte imide und bisimide.
US4404381A (en) * 1981-06-19 1983-09-13 The Dow Chemical Company Novel 3,5-diketo-piperazinyl compounds containing epoxide substituted imides
US4536564A (en) * 1983-12-09 1985-08-20 The Dow Chemical Company Polyamide from bis-carboxy containing 3,5,3',5'-tetraoxo-1,2-dipiperazine compound and diamine

Also Published As

Publication number Publication date
EP0140327A3 (en) 1986-07-23
CA1244430A (en) 1988-11-08
AU571273B2 (en) 1988-04-14
NO170682B (no) 1992-08-10
ES537206A0 (es) 1985-09-01
EP0140327B1 (de) 1990-05-23
JPS6097963A (ja) 1985-05-31
NO170682C (no) 1992-11-18
US4650799A (en) 1987-03-17
DK162639C (da) 1992-04-13
DK162639B (da) 1991-11-25
EP0140327A2 (de) 1985-05-08
NO844183L (no) 1985-05-02
AU3441684A (en) 1985-05-09
JPS6334153B2 (de) 1988-07-08
ES8507513A1 (es) 1985-09-01
DK493384A (da) 1985-05-01
DK493384D0 (da) 1984-10-16

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee