DK162639C - Bis-dioxopiperazin-derivater, fremgangsmaade til fremstilling heraf og antitumormiddel - Google Patents

Bis-dioxopiperazin-derivater, fremgangsmaade til fremstilling heraf og antitumormiddel

Info

Publication number
DK162639C
DK162639C DK493384A DK493384A DK162639C DK 162639 C DK162639 C DK 162639C DK 493384 A DK493384 A DK 493384A DK 493384 A DK493384 A DK 493384A DK 162639 C DK162639 C DK 162639C
Authority
DK
Denmark
Prior art keywords
antitumum
bis
procedures
preparing
agent
Prior art date
Application number
DK493384A
Other languages
English (en)
Other versions
DK493384A (da
DK162639B (da
DK493384D0 (da
Inventor
Jun-Chao Cai
Muneaki Takase
Original Assignee
Zenyaku Kogyo Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zenyaku Kogyo Kk filed Critical Zenyaku Kogyo Kk
Publication of DK493384D0 publication Critical patent/DK493384D0/da
Publication of DK493384A publication Critical patent/DK493384A/da
Publication of DK162639B publication Critical patent/DK162639B/da
Application granted granted Critical
Publication of DK162639C publication Critical patent/DK162639C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/06—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members
    • C07D241/08—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK493384A 1983-10-31 1984-10-16 Bis-dioxopiperazin-derivater, fremgangsmaade til fremstilling heraf og antitumormiddel DK162639C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP58204448A JPS6097963A (ja) 1983-10-31 1983-10-31 ビス−ジオキソピペラジン誘導体，その製造方法及びそれからなる抗腫瘍剤
JP20444883 1983-10-31

Publications (4)

Publication Number Publication Date
DK493384D0 DK493384D0 (da) 1984-10-16
DK493384A DK493384A (da) 1985-05-01
DK162639B DK162639B (da) 1991-11-25
DK162639C true DK162639C (da) 1992-04-13

Family

ID=16490690

Family Applications (1)

Application Number Title Priority Date Filing Date
DK493384A DK162639C (da) 1983-10-31 1984-10-16 Bis-dioxopiperazin-derivater, fremgangsmaade til fremstilling heraf og antitumormiddel

Country Status (9)

Country Link
US (1) US4650799A (da)
EP (1) EP0140327B1 (da)
JP (1) JPS6097963A (da)
AU (1) AU571273B2 (da)
CA (1) CA1244430A (da)
DE (1) DE3482322D1 (da)
DK (1) DK162639C (da)
ES (1) ES8507513A1 (da)
NO (1) NO170682C (da)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0674251B2 (ja) * 1986-02-07 1994-09-21 全薬工業株式▲会▼社 ビス−ジオキソピペラジン誘導体
WO1992000971A1 (en) * 1990-07-04 1992-01-23 Zenyaku Kogyo Kabushiki Kaisha Water-soluble bis-dioxopiperazine derivative
CA2937222C (en) * 2009-06-25 2019-06-04 Alkermes Pharma Ireland Limited Prodrugs of nh-acidic compounds

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL273692A (da) * 1961-01-19 1900-01-01
GB1234935A (en) * 1967-07-03 1971-06-09 Nat Res Dev Piperazine derivatives
GB1236947A (en) * 1968-08-15 1971-06-23 Ici Ltd Process for the preparation of piperazine derivatives
DE2511891A1 (de) * 1975-03-19 1976-10-07 Gruenenthal Chemie Neue derivate des 2,6-dioxopiperazins, verfahren zu ihrer herstellung, diese verbindungen enthaltende arzneimittel sowie verfahren zu deren herstellung
CH635828A5 (de) * 1978-08-30 1983-04-29 Ciba Geigy Ag N-substituierte imide und bisimide.
US4404381A (en) * 1981-06-19 1983-09-13 The Dow Chemical Company Novel 3,5-diketo-piperazinyl compounds containing epoxide substituted imides
US4536564A (en) * 1983-12-09 1985-08-20 The Dow Chemical Company Polyamide from bis-carboxy containing 3,5,3',5'-tetraoxo-1,2-dipiperazine compound and diamine

Also Published As

Publication number Publication date
CA1244430A (en) 1988-11-08
DK493384A (da) 1985-05-01
NO170682C (no) 1992-11-18
JPS6097963A (ja) 1985-05-31
JPS6334153B2 (da) 1988-07-08
ES537206A0 (es) 1985-09-01
DK162639B (da) 1991-11-25
ES8507513A1 (es) 1985-09-01
EP0140327A3 (en) 1986-07-23
AU571273B2 (en) 1988-04-14
EP0140327B1 (en) 1990-05-23
DK493384D0 (da) 1984-10-16
NO170682B (no) 1992-08-10
NO844183L (no) 1985-05-02
EP0140327A2 (en) 1985-05-08
AU3441684A (en) 1985-05-09
US4650799A (en) 1987-03-17
DE3482322D1 (de) 1990-06-28

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Legal Events

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PBP Patent lapsed