DE3431536A1 - Derivatisierte nucleinsaeure-sequenz, verfahren zu deren herstellung sowie deren verwendung zum nachweis von nucleinsaeuren - Google Patents

Derivatisierte nucleinsaeure-sequenz, verfahren zu deren herstellung sowie deren verwendung zum nachweis von nucleinsaeuren

Info

Publication number
DE3431536A1
DE3431536A1 DE19843431536 DE3431536A DE3431536A1 DE 3431536 A1 DE3431536 A1 DE 3431536A1 DE 19843431536 DE19843431536 DE 19843431536 DE 3431536 A DE3431536 A DE 3431536A DE 3431536 A1 DE3431536 A1 DE 3431536A1
Authority
DE
Germany
Prior art keywords
nucleic acid
acid sequence
partner
general formula
immunological reaction
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19843431536
Other languages
German (de)
English (en)
Inventor
Hermann Dr.rer.nat. 8000 München Graf
Helmut Dr.rer.nat. 8132 Tutzing Lenz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Boehringer Mannheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim GmbH filed Critical Boehringer Mannheim GmbH
Priority to DE19843431536 priority Critical patent/DE3431536A1/de
Priority to AU46484/85A priority patent/AU582380B2/en
Priority to CA000489275A priority patent/CA1242657A/en
Priority to DE8585110543T priority patent/DE3574383D1/de
Priority to AT85110543T priority patent/ATE48141T1/de
Priority to EP85110543A priority patent/EP0173251B1/de
Priority to JP60187555A priority patent/JPS6160697A/ja
Publication of DE3431536A1 publication Critical patent/DE3431536A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
DE19843431536 1984-08-28 1984-08-28 Derivatisierte nucleinsaeure-sequenz, verfahren zu deren herstellung sowie deren verwendung zum nachweis von nucleinsaeuren Withdrawn DE3431536A1 (de)

Priority Applications (7)

Application Number Priority Date Filing Date Title
DE19843431536 DE3431536A1 (de) 1984-08-28 1984-08-28 Derivatisierte nucleinsaeure-sequenz, verfahren zu deren herstellung sowie deren verwendung zum nachweis von nucleinsaeuren
AU46484/85A AU582380B2 (en) 1984-08-28 1985-08-21 Derivatised nucleic acid sequences
CA000489275A CA1242657A (en) 1984-08-28 1985-08-22 Derivatised nucleic acid sequences
DE8585110543T DE3574383D1 (en) 1984-08-28 1985-08-22 Nucleic-acids sequence derivatives, process for their preparation and their use in the determination of nucleic acids
AT85110543T ATE48141T1 (de) 1984-08-28 1985-08-22 Derivatisierte nucleinsaeure-sequenz, verfahren zu deren herstellung sowie deren verwendung zum nachweis von nucleinsaeuren.
EP85110543A EP0173251B1 (de) 1984-08-28 1985-08-22 Derivatisierte Nucleinsäure-Sequenz, Verfahren zu deren Herstellung sowie deren Verwendung zum Nachweis von Nucleinsäuren
JP60187555A JPS6160697A (ja) 1984-08-28 1985-08-28 新規な誘導体化核酸配列、その製法および核酸ないし核酸配列の検出法

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19843431536 DE3431536A1 (de) 1984-08-28 1984-08-28 Derivatisierte nucleinsaeure-sequenz, verfahren zu deren herstellung sowie deren verwendung zum nachweis von nucleinsaeuren

Publications (1)

Publication Number Publication Date
DE3431536A1 true DE3431536A1 (de) 1986-03-13

Family

ID=6244044

Family Applications (2)

Application Number Title Priority Date Filing Date
DE19843431536 Withdrawn DE3431536A1 (de) 1984-08-28 1984-08-28 Derivatisierte nucleinsaeure-sequenz, verfahren zu deren herstellung sowie deren verwendung zum nachweis von nucleinsaeuren
DE8585110543T Expired DE3574383D1 (en) 1984-08-28 1985-08-22 Nucleic-acids sequence derivatives, process for their preparation and their use in the determination of nucleic acids

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE8585110543T Expired DE3574383D1 (en) 1984-08-28 1985-08-22 Nucleic-acids sequence derivatives, process for their preparation and their use in the determination of nucleic acids

Country Status (6)

Country Link
EP (1) EP0173251B1 (https=)
JP (1) JPS6160697A (https=)
AT (1) ATE48141T1 (https=)
AU (1) AU582380B2 (https=)
CA (1) CA1242657A (https=)
DE (2) DE3431536A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5354657A (en) * 1988-01-12 1994-10-11 Boehringer Mannheim Gmbh Process for the highly specific detection of nucleic acids in solid

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1988010313A1 (en) * 1987-06-26 1988-12-29 E.I. Du Pont De Nemours And Company Affinity removal of contaminating sequences from recombinant cloned na using capture beads
US5525465A (en) * 1987-10-28 1996-06-11 Howard Florey Institute Of Experimental Physiology And Medicine Oligonucleotide-polyamide conjugates and methods of production and applications of the same
DE3856406T2 (de) * 1987-10-28 2000-10-19 Howard Florey Institute Of Experimental Physiology And Medicine, Parkville Oligonucleotid-polyamid konjugate
DE3813278A1 (de) * 1988-01-12 1989-07-20 Boehringer Mannheim Gmbh Verfahren zum nachweis von nukleinsaeuren
DE3800644A1 (de) * 1988-01-12 1989-07-20 Boehringer Mannheim Gmbh Verfahren zum hochspezifischen nachweis von nukleinsaeuren in loesung
FR2627590A1 (fr) * 1988-02-24 1989-08-25 Ire Celltarg Sa Sonde d'acides nucleiques comportant un nucleotide terminal modifie chimiquement en 5(prime) (oh) en vue de son marquage non radioactif et procedes de preparation
FR2634211B1 (fr) * 1988-07-13 1992-06-26 Lebacq Philippe Procede de marquage d'une sonde nucleique et trousse de reactifs pour la mise en oeuvre de ce procede
FR2644163B2 (fr) * 1988-07-13 1994-09-30 Bioprobe Systems Sa Procede de marquage d'une sonde nucleique et trousse de reactifs pour la mise en oeuvre de ce procede
DE3836656A1 (de) * 1988-10-27 1990-05-03 Boehringer Mannheim Gmbh Neue digoxigenin-derivate und ihre verwendung
US5356773A (en) * 1989-05-16 1994-10-18 Kinetic Investments Limited Generation of unidirectional deletion mutants
DE3916595A1 (de) * 1989-05-22 1990-11-29 Boehringer Mannheim Gmbh Verfahren zur nichtradioaktiven messung der nucleinsaeuresynthese in eukaryontischen zellen
DE3916871A1 (de) * 1989-05-24 1990-11-29 Boehringer Mannheim Gmbh Modifiziertes phosphoramidit-verfahren zur herstellung von modifizierten nukleinsaeuren
EP0422861B1 (en) * 1989-10-13 2000-05-17 Zeneca Limited Probes
US5677440A (en) * 1990-07-16 1997-10-14 Howard Florey Institute Of Experimental Physiology And Medicine Oligonucleotide-polyamide conjugates
EP0752474A1 (en) 1995-07-07 1997-01-08 Boehringer Mannheim Gmbh Nucleic acid coding for CMP-N-acetyl-neuraminic acid hydroxylase and its use for the production of modified glycoproteins
EP0838025B1 (en) * 1995-07-13 2007-04-25 Applera Corporation Self-contained device integrating nucleic acid extraction, amplification and detection
EP1006184A1 (en) 1998-12-03 2000-06-07 F. Hoffmann-La Roche Ag IGF-1 receptor interacting proteins (IIPs) genes coding therefor and uses thereof
US20020146728A1 (en) 1998-12-03 2002-10-10 Tanja Ligensa IGF-1 receptor interacting proteins
EP1099757B1 (en) 1999-11-11 2010-02-24 F. Hoffmann-La Roche Ag Process for the determination of CTp11 and for determining whether a tumor sample has metatastic potential
EP1287129A1 (en) 2000-05-19 2003-03-05 F.Hoffmann-La Roche Ag A process for determing the tumoricidal potential of a sample by the use of a nucleic acid which is downregulated in human tumor cells
CN101061725B (zh) 2004-11-19 2010-08-11 松下电器产业株式会社 运动图像编码方法以及运动图像解码方法
DE602006014106D1 (de) 2005-03-14 2010-06-17 Link Genomics Inc Verfahren zur diagnose von prostatakrebs

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2422956A1 (fr) * 1978-04-13 1979-11-09 Pasteur Institut Procede de detection et de caracterisation d'un acide nucleique ou d'une sequence de celui-ci, et reactif enzymatique pour la mise en oeuvre de ce procede
CA1219824A (en) * 1981-04-17 1987-03-31 David C. Ward Modified nucleotides and methods of preparing and using same
FR2519005B1 (fr) * 1981-12-29 1985-10-25 Pasteur Institut Fragments d'adn marques a l'une au moins de leurs extremites par des ribonucleotides modifies reconnaissables par des molecules affines et procede pour realiser une analyse de tels fragments d'adn
US4490472A (en) * 1982-06-17 1984-12-25 Imreg, Inc. Sensitive tests for malignancies based on DNA detection
CA1223831A (en) * 1982-06-23 1987-07-07 Dean Engelhardt Modified nucleotides, methods of preparing and utilizing and compositions containing the same
IL70765A (en) * 1983-01-27 1988-07-31 Enzo Biochem Inc Substrates containing non-radioactive chemically-labeled polynucleotides and methods using them
EP0135587B2 (en) * 1983-02-22 2002-12-18 Syngene, Inc. Defined sequence single strand oligonucleotides incorporating reporter groups, process for the chemical synthesis thereof, and nucleosides useful in such synthesis
US4737454A (en) * 1983-07-14 1988-04-12 Molecular Diagnostics, Inc. Fast photochemical method of labelling nucleic acids for detection purposes in hybridization assays
US4626501A (en) * 1983-09-02 1986-12-02 Integrated Genetics, Inc. Labeled DNA
FR2558172B1 (fr) * 1984-01-16 1986-06-13 Inst Nat Sante Rech Med Sonde contenant un acide nucleique modifie et reconnaissance par des anticorps specifiques et utilisation de cette sonde et de ces anticorps specifiques pour detecter et caracteriser une sequence d'adn homologue

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5354657A (en) * 1988-01-12 1994-10-11 Boehringer Mannheim Gmbh Process for the highly specific detection of nucleic acids in solid

Also Published As

Publication number Publication date
EP0173251B1 (de) 1989-11-23
AU4648485A (en) 1986-03-06
EP0173251A3 (en) 1986-10-29
JPS6160697A (ja) 1986-03-28
JPH0578320B2 (https=) 1993-10-28
CA1242657A (en) 1988-10-04
DE3574383D1 (en) 1989-12-28
ATE48141T1 (de) 1989-12-15
AU582380B2 (en) 1989-03-23
EP0173251A2 (de) 1986-03-05

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Legal Events

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8139 Disposal/non-payment of the annual fee