DE3374934D1 - 8-substituted pyrrolizidine derivatives and use thereof - Google Patents

8-substituted pyrrolizidine derivatives and use thereof

Info

Publication number
DE3374934D1
DE3374934D1 DE8383102561T DE3374934T DE3374934D1 DE 3374934 D1 DE3374934 D1 DE 3374934D1 DE 8383102561 T DE8383102561 T DE 8383102561T DE 3374934 T DE3374934 T DE 3374934T DE 3374934 D1 DE3374934 D1 DE 3374934D1
Authority
DE
Germany
Prior art keywords
pyrrolizidine
lower alkyl
alkyl group
substituted
stands
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8383102561T
Other languages
English (en)
Inventor
Seiji Miyano
Kunihiro Sumoto
Minoru Morita
Fumio Sato
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Suntory Ltd
Original Assignee
Suntory Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Suntory Ltd filed Critical Suntory Ltd
Application granted granted Critical
Publication of DE3374934D1 publication Critical patent/DE3374934D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE8383102561T 1982-03-16 1983-03-15 8-substituted pyrrolizidine derivatives and use thereof Expired DE3374934D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP57042297A JPS58159493A (ja) 1982-03-16 1982-03-16 ８−置換ピロリチジン誘導体およびその用途

Publications (1)

Publication Number Publication Date
DE3374934D1 true DE3374934D1 (en) 1988-01-28

Family

ID=12632091

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8383102561T Expired DE3374934D1 (en) 1982-03-16 1983-03-15 8-substituted pyrrolizidine derivatives and use thereof

Country Status (9)

Country Link
US (1) US4564624A (de)
EP (1) EP0089061B1 (de)
JP (1) JPS58159493A (de)
AT (1) ATE31414T1 (de)
AU (1) AU554261B2 (de)
CA (1) CA1210401A (de)
DE (1) DE3374934D1 (de)
DK (1) DK160309C (de)
ES (2) ES521032A0 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60184079A (ja) * 1984-02-29 1985-09-19 Suntory Ltd ピロリチジン誘導体
JPS6122084A (ja) * 1984-07-06 1986-01-30 Suntory Ltd ピロリチジン化合物、その製造法およびその用途
JPS6222785A (ja) * 1985-07-23 1987-01-30 Sanwa Kagaku Kenkyusho:Kk 新規な２−オキソピロリジン化合物及びその塩、その製法並びにこれらを有効成分とする脳機能障害の予防及び治療剤
JPS6256489A (ja) * 1985-09-04 1987-03-12 Sanwa Kagaku Kenkyusho:Kk 新規なピロリチジン化合物及びその塩、これらの製法並びにこれらを有効成分とする消化性潰瘍治療剤
US4638006A (en) * 1985-09-24 1987-01-20 Warner Lambert Company Amnesia reversal with N,N-dialkylaminoalkyl-hexahydro-5-oxo 1H-pyrrolizine-3-carboxamides
AU1578692A (en) * 1991-03-07 1992-10-06 G.D. Searle & Co. New meso-azacyclic aromatic acid amides and esters as novel serotonergic agents
US5516782A (en) * 1991-03-07 1996-05-14 G. D. Searle & Co. New meso-azacyclic aromatic acid amides and esters as novel serotonergic agents
JP2706057B2 (ja) * 1995-06-14 1998-01-28 勝之 岸 自動車用トイレ
JP4317693B2 (ja) * 2001-05-31 2009-08-19 ニプロパッチ株式会社 経皮吸収用医薬組成物
US7473407B2 (en) * 2004-11-19 2009-01-06 Solvay Chemicals Magnetic separation process for trona
CN103864796B (zh) * 2012-12-18 2016-04-27 北京嘉林药业股份有限公司 一种盐酸吡西卡尼的纯化生产方法
KR102351052B1 (ko) * 2019-12-26 2022-01-14 보령제약 주식회사 피롤리지딘 화합물 제조 방법 및 피롤리지딘 염산염 1/2 수화물 제조 방법

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS56156283A (en) * 1980-05-07 1981-12-02 Suntory Ltd 8-substituted pyrrolitidine and its quaternary ammonium salt

Also Published As

Publication number Publication date
ES8500277A1 (es) 1984-11-01
DK121383A (da) 1983-09-17
ES521032A0 (es) 1984-11-01
ES533620A0 (es) 1985-06-16
EP0089061A2 (de) 1983-09-21
DK121383D0 (da) 1983-03-16
ATE31414T1 (de) 1988-01-15
AU1214083A (en) 1983-09-22
JPS58159493A (ja) 1983-09-21
EP0089061A3 (en) 1984-07-18
DK160309C (da) 1991-07-29
US4564624A (en) 1986-01-14
AU554261B2 (en) 1986-08-14
CA1210401A (en) 1986-08-26
ES8505683A1 (es) 1985-06-16
JPH0446956B2 (de) 1992-07-31
EP0089061B1 (de) 1987-12-16
DK160309B (da) 1991-02-25

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition