ES8505683A1 - Procedimiento de preparar derivados pirrolicidinicos 8-substituidos - Google Patents
Procedimiento de preparar derivados pirrolicidinicos 8-substituidosInfo
- Publication number
- ES8505683A1 ES8505683A1 ES533620A ES533620A ES8505683A1 ES 8505683 A1 ES8505683 A1 ES 8505683A1 ES 533620 A ES533620 A ES 533620A ES 533620 A ES533620 A ES 533620A ES 8505683 A1 ES8505683 A1 ES 8505683A1
- Authority
- ES
- Spain
- Prior art keywords
- pyrrolizidine
- lower alkyl
- alkyl group
- substituted
- stands
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Saccharide Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
PROCEDIMIENTO PARA LA PREPARACION DE DERIVADOS PIRROLICIDINICOS 8-SUSTITUIDOS Y, EN PARTICULAR, PARA PREPARAR COMPUESTOS DE FORMULA GENERAL (I) EN LA QUE R SIGNIFICA UN GRUPO ALQUILO INFERIOR; R SIGNIFICA HIDROGENO; Y R SIGNIFICA UN GRUPO ALQUILO INFERIOR, ALCOXI INFERIOR O UN GRUPO HALOGENO.CONSISTE EN HACER REACCIONAR ACIDO 8-PIRROLICIDINACETICO CON EL CORRESPONDIENTE DERIVADO DE ANILINA, DE FORMULA GENERAL (II).DE APLICACION EN MEDICINA COMO AGENTE ANTIARRITMICO.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP57042297A JPS58159493A (ja) | 1982-03-16 | 1982-03-16 | 8−置換ピロリチジン誘導体およびその用途 |
Publications (2)
Publication Number | Publication Date |
---|---|
ES533620A0 ES533620A0 (es) | 1985-06-16 |
ES8505683A1 true ES8505683A1 (es) | 1985-06-16 |
Family
ID=12632091
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES521032A Granted ES521032A0 (es) | 1982-03-16 | 1983-03-16 | Procedimiento de preparar derivados pirrolicidinicos 8 substituidos. |
ES533620A Expired ES8505683A1 (es) | 1982-03-16 | 1984-06-22 | Procedimiento de preparar derivados pirrolicidinicos 8-substituidos |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES521032A Granted ES521032A0 (es) | 1982-03-16 | 1983-03-16 | Procedimiento de preparar derivados pirrolicidinicos 8 substituidos. |
Country Status (9)
Country | Link |
---|---|
US (1) | US4564624A (es) |
EP (1) | EP0089061B1 (es) |
JP (1) | JPS58159493A (es) |
AT (1) | ATE31414T1 (es) |
AU (1) | AU554261B2 (es) |
CA (1) | CA1210401A (es) |
DE (1) | DE3374934D1 (es) |
DK (1) | DK160309C (es) |
ES (2) | ES521032A0 (es) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS60184079A (ja) * | 1984-02-29 | 1985-09-19 | Suntory Ltd | ピロリチジン誘導体 |
JPS6122084A (ja) * | 1984-07-06 | 1986-01-30 | Suntory Ltd | ピロリチジン化合物、その製造法およびその用途 |
JPS6222785A (ja) * | 1985-07-23 | 1987-01-30 | Sanwa Kagaku Kenkyusho:Kk | 新規な2−オキソピロリジン化合物及びその塩、その製法並びにこれらを有効成分とする脳機能障害の予防及び治療剤 |
JPS6256489A (ja) * | 1985-09-04 | 1987-03-12 | Sanwa Kagaku Kenkyusho:Kk | 新規なピロリチジン化合物及びその塩、これらの製法並びにこれらを有効成分とする消化性潰瘍治療剤 |
US4638006A (en) * | 1985-09-24 | 1987-01-20 | Warner Lambert Company | Amnesia reversal with N,N-dialkylaminoalkyl-hexahydro-5-oxo 1H-pyrrolizine-3-carboxamides |
US5516782A (en) * | 1991-03-07 | 1996-05-14 | G. D. Searle & Co. | New meso-azacyclic aromatic acid amides and esters as novel serotonergic agents |
AU1578692A (en) * | 1991-03-07 | 1992-10-06 | G.D. Searle & Co. | New meso-azacyclic aromatic acid amides and esters as novel serotonergic agents |
JP2706057B2 (ja) * | 1995-06-14 | 1998-01-28 | 勝之 岸 | 自動車用トイレ |
WO2002096465A1 (fr) * | 2001-05-31 | 2002-12-05 | Saitama Daiichi Pharmaceutical Co., Ltd. | Compositions medicinales pour absorption percutanee |
US7473407B2 (en) * | 2004-11-19 | 2009-01-06 | Solvay Chemicals | Magnetic separation process for trona |
CN103864796B (zh) * | 2012-12-18 | 2016-04-27 | 北京嘉林药业股份有限公司 | 一种盐酸吡西卡尼的纯化生产方法 |
KR102351052B1 (ko) * | 2019-12-26 | 2022-01-14 | 보령제약 주식회사 | 피롤리지딘 화합물 제조 방법 및 피롤리지딘 염산염 1/2 수화물 제조 방법 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS56156283A (en) * | 1980-05-07 | 1981-12-02 | Suntory Ltd | 8-substituted pyrrolitidine and its quaternary ammonium salt |
-
1982
- 1982-03-16 JP JP57042297A patent/JPS58159493A/ja active Granted
-
1983
- 1983-03-08 AU AU12140/83A patent/AU554261B2/en not_active Expired
- 1983-03-10 US US06/473,947 patent/US4564624A/en not_active Expired - Lifetime
- 1983-03-15 DE DE8383102561T patent/DE3374934D1/de not_active Expired
- 1983-03-15 AT AT83102561T patent/ATE31414T1/de not_active IP Right Cessation
- 1983-03-15 EP EP83102561A patent/EP0089061B1/en not_active Expired
- 1983-03-15 CA CA000423638A patent/CA1210401A/en not_active Expired
- 1983-03-16 ES ES521032A patent/ES521032A0/es active Granted
- 1983-03-16 DK DK121383A patent/DK160309C/da not_active IP Right Cessation
-
1984
- 1984-06-22 ES ES533620A patent/ES8505683A1/es not_active Expired
Also Published As
Publication number | Publication date |
---|---|
EP0089061A2 (en) | 1983-09-21 |
AU1214083A (en) | 1983-09-22 |
DK160309C (da) | 1991-07-29 |
JPH0446956B2 (es) | 1992-07-31 |
EP0089061B1 (en) | 1987-12-16 |
DE3374934D1 (en) | 1988-01-28 |
ES533620A0 (es) | 1985-06-16 |
ATE31414T1 (de) | 1988-01-15 |
DK160309B (da) | 1991-02-25 |
ES8500277A1 (es) | 1984-11-01 |
DK121383A (da) | 1983-09-17 |
CA1210401A (en) | 1986-08-26 |
DK121383D0 (da) | 1983-03-16 |
US4564624A (en) | 1986-01-14 |
JPS58159493A (ja) | 1983-09-21 |
ES521032A0 (es) | 1984-11-01 |
EP0089061A3 (en) | 1984-07-18 |
AU554261B2 (en) | 1986-08-14 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 20041102 |