DE3317666C2 - - Google Patents

Info

Publication number
DE3317666C2
DE3317666C2 DE3317666A DE3317666A DE3317666C2 DE 3317666 C2 DE3317666 C2 DE 3317666C2 DE 3317666 A DE3317666 A DE 3317666A DE 3317666 A DE3317666 A DE 3317666A DE 3317666 C2 DE3317666 C2 DE 3317666C2
Authority
DE
Germany
Prior art keywords
pyrrolyl
mixture
water
acid
dissolved
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE3317666A
Other languages
German (de)
English (en)
Other versions
DE3317666A1 (de
Inventor
Francisco Salto Maldonado
Luis Costa Pla
Jose Luis Fernandez Leon Es Puentes
Jose Maria Fernandez Villanueva De La Canada Madrid Es Sousa-Faro
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Antibioticos SA
Original Assignee
Antibioticos SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Antibioticos SA filed Critical Antibioticos SA
Publication of DE3317666A1 publication Critical patent/DE3317666A1/de
Application granted granted Critical
Publication of DE3317666C2 publication Critical patent/DE3317666C2/de
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/325—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
    • C07D207/327—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pyrrole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE3317666A 1982-05-17 1983-05-14 Verfahren zur herstellung von (alpha)-(n-pyrrolyl)-substituierten saeuren, deren salzen und estern, sowie dieselben enthaltende pharmazeutische zusammensetzungen Granted DE3317666A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES512268A ES512268A0 (es) 1982-05-17 1982-05-17 "procedimiento de obtencion de acidos alfa-n-pirrolil-derivados".

Publications (2)

Publication Number Publication Date
DE3317666A1 DE3317666A1 (de) 1983-11-17
DE3317666C2 true DE3317666C2 (US20070244113A1-20071018-C00087.png) 1990-10-25

Family

ID=8484145

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3317666A Granted DE3317666A1 (de) 1982-05-17 1983-05-14 Verfahren zur herstellung von (alpha)-(n-pyrrolyl)-substituierten saeuren, deren salzen und estern, sowie dieselben enthaltende pharmazeutische zusammensetzungen

Country Status (8)

Country Link
US (1) US4563477A (US20070244113A1-20071018-C00087.png)
JP (1) JPS5910563A (US20070244113A1-20071018-C00087.png)
BE (1) BE896769A (US20070244113A1-20071018-C00087.png)
CH (1) CH658786A5 (US20070244113A1-20071018-C00087.png)
DE (1) DE3317666A1 (US20070244113A1-20071018-C00087.png)
ES (1) ES512268A0 (US20070244113A1-20071018-C00087.png)
FR (1) FR2526793B1 (US20070244113A1-20071018-C00087.png)
GB (1) GB2122189B (US20070244113A1-20071018-C00087.png)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3727114A1 (de) * 1987-08-14 1989-02-23 Basf Ag Verfahren zur herstellung von pyrrolen
FR2647674B1 (fr) * 1989-06-06 1994-06-03 Centre Nat Rech Scient Derives de pyrrole utilisables notamment comme intercepteurs d'especes activees du dioxygene - leur procede de preparation - compositions les contenant
CA2036192A1 (en) 1990-02-13 1991-08-14 Nicholas Meanwell Heterocyclic carboxylic acids and esters
US5034409A (en) * 1990-02-13 1991-07-23 Bristol-Myers Squibb Company Pyrrole carboxylic acids and esters for blood platelet aggregation inhibition
KR101044880B1 (ko) * 2008-06-12 2011-06-28 일양약품주식회사 항궤양제 화합물의 합성에 유용한 중간체의 제조방법

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS50130756A (US20070244113A1-20071018-C00087.png) * 1974-03-30 1975-10-16
DE2647368A1 (de) * 1975-10-23 1977-05-05 Ciba Geigy Ag Alpha-(1-pyrrolyl)-carbonsaeure-3- phenoxy-benzylester, verfahren zu ihrer herstellung und ihre verwendung
JPS52128369A (en) * 1976-04-17 1977-10-27 Nissan Chem Ind Ltd Alpha-isopropyl-substituted pyrrole-1-acetic acid ester
JPS5326322A (en) * 1976-08-20 1978-03-11 Nissan Chem Ind Ltd Insecticidal composition

Also Published As

Publication number Publication date
GB8312804D0 (en) 1983-06-15
ES8404325A1 (es) 1984-05-16
FR2526793B1 (fr) 1985-09-06
JPS5910563A (ja) 1984-01-20
GB2122189A (en) 1984-01-11
CH658786A5 (fr) 1986-12-15
ES512268A0 (es) 1984-05-16
FR2526793A1 (fr) 1983-11-18
BE896769A (fr) 1983-09-16
US4563477A (en) 1986-01-07
DE3317666A1 (de) 1983-11-17
GB2122189B (en) 1986-04-16

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Legal Events

Date Code Title Description
8128 New person/name/address of the agent

Representative=s name: VOSSIUS, V., DIPL.-CHEM. DR.RER.NAT. VOSSIUS, D.,

8110 Request for examination paragraph 44
8128 New person/name/address of the agent

Representative=s name: VOSSIUS, V., DIPL.-CHEM. DR.RER.NAT. TAUCHNER, P.,

D2 Grant after examination
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Free format text: STOLBERG-WERNIGERODE, GRAF ZU, U., DIPL.-CHEM. DR.RER.NAT. SUCHANTKE, J., DIPL.-ING. HUBER, A., DIPL.-ING. KAMEKE, VON, A., DIPL.-CHEM. DR.RER.NAT., 2000 HAMBURG SCHULMEYER, K., DIPL.-CHEM. DR.RER.NAT., PAT.-ANWAELTE, 2087 HASLOH

8328 Change in the person/name/address of the agent

Free format text: TAUCHNER, P., DIPL.-CHEM. DR.RER.NAT. HEUNEMANN, D., DIPL.-PHYS. DR.RER.NAT. RAUH, P., DIPL.-CHEM. DR.RER.NAT. HERMANN, G., DIPL.-PHYS. DR.RER.NAT., PAT.-ANWAELTE, 8000 MUENCHEN

8339 Ceased/non-payment of the annual fee