DE3311753A1 - Substituierte 6-aryl-1,2,4-triazolo(4,3-b)pyridazine - ihre herstellung und verwendung - - Google Patents

Substituierte 6-aryl-1,2,4-triazolo(4,3-b)pyridazine - ihre herstellung und verwendung -

Info

Publication number
DE3311753A1
DE3311753A1 DE19833311753 DE3311753A DE3311753A1 DE 3311753 A1 DE3311753 A1 DE 3311753A1 DE 19833311753 DE19833311753 DE 19833311753 DE 3311753 A DE3311753 A DE 3311753A DE 3311753 A1 DE3311753 A1 DE 3311753A1
Authority
DE
Germany
Prior art keywords
carbon atoms
formula
alkyl
phenyl
chlorine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19833311753
Other languages
German (de)
English (en)
Inventor
Franz Dr. 6110 Dieburg Hock
Manfred Dr. 6239 Eppstein Rösner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Priority to DE19833311753 priority Critical patent/DE3311753A1/de
Priority to DK144884A priority patent/DK144884A/da
Priority to HU841204A priority patent/HU189076B/hu
Priority to AT84710009T priority patent/ATE32723T1/de
Priority to DE8484710009T priority patent/DE3469530D1/de
Priority to EP84710009A priority patent/EP0121490B1/de
Priority to FI841238A priority patent/FI841238A/fi
Priority to ES531084A priority patent/ES531084A0/es
Priority to NZ207691A priority patent/NZ207691A/en
Priority to GR74257A priority patent/GR81812B/el
Priority to PH30469A priority patent/PH20465A/en
Priority to KR1019840001627A priority patent/KR840008361A/ko
Priority to ZA842389A priority patent/ZA842389B/xx
Priority to AU26346/84A priority patent/AU563556B2/en
Priority to JP59061286A priority patent/JPS59184179A/ja
Priority to PT78343A priority patent/PT78343B/pt
Priority to IL71412A priority patent/IL71412A/xx
Priority to CA000451005A priority patent/CA1246568A/en
Priority to NO841270A priority patent/NO841270L/no
Priority to MA20302A priority patent/MA20080A1/fr
Publication of DE3311753A1 publication Critical patent/DE3311753A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Steroid Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
DE19833311753 1983-03-31 1983-03-31 Substituierte 6-aryl-1,2,4-triazolo(4,3-b)pyridazine - ihre herstellung und verwendung - Withdrawn DE3311753A1 (de)

Priority Applications (20)

Application Number Priority Date Filing Date Title
DE19833311753 DE3311753A1 (de) 1983-03-31 1983-03-31 Substituierte 6-aryl-1,2,4-triazolo(4,3-b)pyridazine - ihre herstellung und verwendung -
DK144884A DK144884A (da) 1983-03-31 1984-02-29 Substituerede 6-aryl-1,2,4-triazolo(4,3-b)pyridaziner, deres fremstilling og anvendelse
HU841204A HU189076B (en) 1983-03-31 1984-03-26 Process for the production of substituted 6-aryl-1,2,4-triazolo/4,3-b/-pyridazin-derivatives and of pharmaceutic products containing such compounds
AT84710009T ATE32723T1 (de) 1983-03-31 1984-03-28 Substituierte 6-aryl-1,2,4-triazolo(4,3b>pyridazine, ihre herstellung und verwendung.
DE8484710009T DE3469530D1 (en) 1983-03-31 1984-03-28 Substituted 6-aryl-1,2,4-triazoloû4,3-b¨pyridazines, their preparation and use
EP84710009A EP0121490B1 (de) 1983-03-31 1984-03-28 Substituierte 6-Aryl-1,2,4-triazolo[4,3-b]pyridazine, ihre Herstellung und Verwendung
FI841238A FI841238A (fi) 1983-03-31 1984-03-28 Substituerade 6-aryl-1,2,4- triazolo/4, 3-b/pyridaziner, deras framstaellning och anvaendning.
ES531084A ES531084A0 (es) 1983-03-31 1984-03-29 Procedimiento para preparar 6-aril-1,2,4,-triazolo (4,3-b) piridazinas substituidas
NZ207691A NZ207691A (en) 1983-03-31 1984-03-29 1,2,4-triazolo(4,3-b)pyridazine derivatives and pharmaceutical compositions
GR74257A GR81812B (el) 1983-03-31 1984-03-29
PH30469A PH20465A (en) 1983-03-31 1984-03-29 Substituted 6 aryl 1,2,4 triazolo 4,3-b pyridazines
KR1019840001627A KR840008361A (ko) 1983-03-31 1984-03-29 치환된 6-아릴-1,2,4-트리아졸로[4,3-b]피리다진의 제조방법
ZA842389A ZA842389B (en) 1983-03-31 1984-03-30 Substituted 6-aryl-1,2,4-triazolo(4,3-b)pyridazines-their preparation and their use
AU26346/84A AU563556B2 (en) 1983-03-31 1984-03-30 Substituted 6-aryl-1,2,4-triazolo (4,3-b) pyridazines
JP59061286A JPS59184179A (ja) 1983-03-31 1984-03-30 置換された６−アリ−ル−１，２，４−トリアゾロ〔４，３−ｂ〕ピリダジンおよびそれらの製法
PT78343A PT78343B (de) 1983-03-31 1984-03-30 Substituierte 6-aryl-1,2,4-triazolo<4,3-b>pyridazine ihre herstellung und verwendung
IL71412A IL71412A (en) 1983-03-31 1984-03-30 3-(substituted amino)-6-aryl-1,2,4-triazolo(4,3-b)-pyridazines,their preparation and pharmaceutical compositions containing them
CA000451005A CA1246568A (en) 1983-03-31 1984-03-30 Substituted 6-aryl-1,2,4-triazolo[4,3- b]pyridazines - their preparation and their use
NO841270A NO841270L (no) 1983-03-31 1984-03-30 Substituerte 6-aryl-1,2,4-triazolo (4,3-b) pyridaziner, samt deres fremstilling og anvendelse
MA20302A MA20080A1 (fr) 1983-03-31 1984-03-31 Procede de preparation de 6-aryl-1,2,4-triazole (4,3b)-pyridazines substituees.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19833311753 DE3311753A1 (de) 1983-03-31 1983-03-31 Substituierte 6-aryl-1,2,4-triazolo(4,3-b)pyridazine - ihre herstellung und verwendung -

Publications (1)

Publication Number Publication Date
DE3311753A1 true DE3311753A1 (de) 1984-10-04

Family

ID=6195196

Family Applications (2)

Application Number Title Priority Date Filing Date
DE19833311753 Withdrawn DE3311753A1 (de) 1983-03-31 1983-03-31 Substituierte 6-aryl-1,2,4-triazolo(4,3-b)pyridazine - ihre herstellung und verwendung -
DE8484710009T Expired DE3469530D1 (en) 1983-03-31 1984-03-28 Substituted 6-aryl-1,2,4-triazoloû4,3-b¨pyridazines, their preparation and use

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE8484710009T Expired DE3469530D1 (en) 1983-03-31 1984-03-28 Substituted 6-aryl-1,2,4-triazoloû4,3-b¨pyridazines, their preparation and use

Country Status (19)

Country Link
EP (1) EP0121490B1 (el)
JP (1) JPS59184179A (el)
KR (1) KR840008361A (el)
AT (1) ATE32723T1 (el)
AU (1) AU563556B2 (el)
CA (1) CA1246568A (el)
DE (2) DE3311753A1 (el)
DK (1) DK144884A (el)
ES (1) ES531084A0 (el)
FI (1) FI841238A (el)
GR (1) GR81812B (el)
HU (1) HU189076B (el)
IL (1) IL71412A (el)
MA (1) MA20080A1 (el)
NO (1) NO841270L (el)
NZ (1) NZ207691A (el)
PH (1) PH20465A (el)
PT (1) PT78343B (el)
ZA (1) ZA842389B (el)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4654343A (en) * 1985-10-31 1987-03-31 American Cyanamid Company N-substituted-N[3-(1,2,4-triazolo[4,3-b]pyridazin-6-yl)phenyl]alkanamides, carbamates and ureas
JP2010500365A (ja) 2006-08-07 2010-01-07 インサイト・コーポレイション キナーゼ阻害剤としてのトリアゾロトリアジン
MX2009005144A (es) 2006-11-22 2009-05-27 Incyte Corp Imidazotriazinas e imidazopirimidinas como inhibidores de cinasa.
CN103936743B (zh) 2008-05-21 2018-04-24 因西特控股公司 2-氟-N-甲基-4-[7-(喹啉-6-基甲基)咪唑并[1,2-b][1,2,4]三嗪-2-基]苯甲酰胺的盐及与其相关的制备方法
CA2788398C (en) 2010-02-03 2018-02-27 Incyte Corporation Imidazo[1,2-b][1,2,4]triazines as c-met inhibitors
CA2834166A1 (en) 2011-04-29 2012-11-01 Amgen Inc. Bicyclic pyridazine compounds as pim inhibitors

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL128809C (el) * 1966-06-18
DE2113438A1 (de) * 1971-03-19 1972-09-21 Boehringer Mannheim Gmbh Nitrofuryl-triazolo[4,3-b]pyridazinderivate
US3915968A (en) * 1973-09-21 1975-10-28 Lepetit Spa Triazolopyridazines
DE3217325A1 (de) * 1982-05-08 1983-11-10 Hoechst Ag, 6230 Frankfurt 3-amino-6-aryl-1,2,4-triazolo(4,3-b)-pyridazine, ihre herstellung und ihre verwendung
DE3222342A1 (de) * 1982-06-14 1983-12-15 Hoechst Ag, 6230 Frankfurt 6-aryl-1,2,4-triazolo (4,3-b) pyridazin-3-carbaminate, ihre herstellung und sie enthaltende arzneimittel

Also Published As

Publication number Publication date
EP0121490A1 (de) 1984-10-10
CA1246568A (en) 1988-12-13
DE3469530D1 (en) 1988-04-07
ES8501765A1 (es) 1984-12-01
HU189076B (en) 1986-06-30
PT78343A (de) 1984-04-01
JPS59184179A (ja) 1984-10-19
IL71412A0 (en) 1984-06-29
AU2634684A (en) 1984-10-04
DK144884A (da) 1984-10-01
NO841270L (no) 1984-10-01
ES531084A0 (es) 1984-12-01
IL71412A (en) 1988-05-31
GR81812B (el) 1984-12-12
DK144884D0 (da) 1984-02-29
FI841238A0 (fi) 1984-03-28
PH20465A (en) 1987-01-14
EP0121490B1 (de) 1988-03-02
PT78343B (de) 1986-07-14
MA20080A1 (fr) 1984-10-01
AU563556B2 (en) 1987-07-16
FI841238A (fi) 1984-10-01
HUT34193A (en) 1985-02-28
ZA842389B (en) 1984-11-28
ATE32723T1 (de) 1988-03-15
NZ207691A (en) 1986-07-11
KR840008361A (ko) 1984-12-14

Similar Documents

Publication Publication Date Title
DE3935514A1 (de) Neue bicyclo-imidazole, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
EP0528922B1 (de) Neue sulfonylverbindungen
EP0181282A1 (de) Triazolochinazolinverbindungen
EP0263352A1 (de) Neue Imidazo-benzoxazinone, ihre Herstellung und diese Verbindungen enthaltende Arzneimittel
EP0327986A2 (de) Arzeneimittel enthaltend Lactame, neue substituierte Lactame und Verfahren zu ihrer Herstellung
DD262023A5 (de) Verfahren zur herstellung von dihydropyridinen
EP1853582A2 (de) Heterocyclylamid-substituierte imidazole
DD152934A5 (de) Verfahren zur herstellung von substituierten 3-amino-sydnoniminen
DE2446821A1 (de) Substituierte 1,3-dimethyl-1hpyrazol eckige klammer auf 3,4b eckige klammer zu -chinoline
DE3311753A1 (de) Substituierte 6-aryl-1,2,4-triazolo(4,3-b)pyridazine - ihre herstellung und verwendung -
EP0094038B1 (de) 3-Amino-6-aryl-1,2,4-triazolo(4,3-b)-pyridazine, ihre Herstellung und ihre Verwendung
EP0007525A1 (de) 2-(4-Aminopiperidino)-3,4-dihydrochinoline, Verfahren zu ihrer Herstellung, pharmazeutische Präparate auf Basis dieser Verbindungen sowie ihre Verwendung
EP0044266A2 (de) Neue substituierte 3,5-Diamino-1,2,4-oxadiazole und 3,5-Diamino-1,2,4-thiadiazole, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Präparate
EP0000336A1 (de) Amidino-benzylpyrimidine, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel
CH641800A5 (de) Pyrido-pyrimidine, verfahren zu ihrer herstellung und die diese verbindungen enthaltenden arzneimittel.
EP0004904B1 (de) 2-Amino-3a,4,5,6-tetrahydro-perimidin-Derivate, diese enthaltende Arzneimittel und Verfahren zu ihrer Herstellung
EP0268178A1 (de) Neue Pyrrolo-benzimidazole, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung
CH634069A5 (en) Process for preparing novel 7-substituted 7H-pyrrolo[3,2-f]quinazoline-1,3-diamines
DE2448257A1 (de) Cumarinabkoemmlinge, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
DE3121137A1 (de) Neue pyridazino(4,5-b)indole, verfahren zu ihrer herstellung, ihre verwendung sowie pharmazeutische praeparate auf basis dieser verbindungen, zwischenprodukte und deren herstellung&#34;
EP0037471A1 (de) 1-Aroyl-2-phenylamino-2-imidazoline, ihre Herstellung und diese enthaltende Arzneimittel
DE3017560A1 (de) 9-amino-6,7-dihydro-4h-pyrido eckige klammer auf 1,2-a eckige klammer zu pyrimidin-4-on-derivate, verfahren zu deren herstellung und diese verbindungen enthaltende pharmazeutische kompositionen
DD202288A5 (de) Verfahren zur herstellung von phenylpiperazinderivaten
DD201594A5 (de) Verfahren zur herstellung von neuen polyazaheterocyclischen verbindungen
AT339905B (de) Verfahren zur herstellung von neuen piperidinderivaten und deren salzen

Legal Events

Date Code Title Description
8139 Disposal/non-payment of the annual fee