DE3166093D1 - N-substituted pseudo-aminosugars, their production and use - Google Patents

N-substituted pseudo-aminosugars, their production and use

Info

Publication number
DE3166093D1
DE3166093D1 DE8181306141T DE3166093T DE3166093D1 DE 3166093 D1 DE3166093 D1 DE 3166093D1 DE 8181306141 T DE8181306141 T DE 8181306141T DE 3166093 T DE3166093 T DE 3166093T DE 3166093 D1 DE3166093 D1 DE 3166093D1
Authority
DE
Germany
Prior art keywords
aminosugars
production
substituted pseudo
pseudo
substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8181306141T
Other languages
English (en)
Inventor
Satoshi Horii
Yukihiko Kameda
Hiroshi Fukase
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP56181A external-priority patent/JPS57114554A/ja
Priority claimed from JP8463581A external-priority patent/JPH0238580B2/ja
Priority claimed from JP15965781A external-priority patent/JPS5859946A/ja
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Application granted granted Critical
Publication of DE3166093D1 publication Critical patent/DE3166093D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36—Radicals substituted by singly-bound nitrogen atoms
    • C07D213/38—Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
DE8181306141T 1981-01-05 1981-12-24 N-substituted pseudo-aminosugars, their production and use Expired DE3166093D1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP56181A JPS57114554A (en) 1981-01-05 1981-01-05 N-substituted derivative of validamine, its preparation, and alpha-glucosidase inhibiting agent
JP8463581A JPH0238580B2 (ja) 1981-06-02 1981-06-02 Bariooruaminnonnchikanjudotai*sonoseizohooyobyoto
JP15965781A JPS5859946A (ja) 1981-10-06 1981-10-06 擬似アミノ糠のｎ−置換誘導体、その製造法および用途

Publications (1)

Publication Number Publication Date
DE3166093D1 true DE3166093D1 (en) 1984-10-18

Family

ID=27274520

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8181306141T Expired DE3166093D1 (en) 1981-01-05 1981-12-24 N-substituted pseudo-aminosugars, their production and use

Country Status (5)

Country Link
US (3) US4701559A (de)
EP (1) EP0056194B1 (de)
CA (1) CA1184181A (de)
DE (1) DE3166093D1 (de)
MX (1) MX9202937A (de)

Families Citing this family (59)

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EP0194794A3 (de) * 1985-03-08 1986-12-17 Takeda Chemical Industries, Ltd. Saccharid-Verdauung hemmende Zusammensetzung
WO1986005094A1 (en) * 1985-03-08 1986-09-12 Takeda Chemical Industries, Ltd. Antiobesity agent and composition
JPS61205455A (ja) * 1985-03-11 1986-09-11 Takeda Chem Ind Ltd 低カロリ−砂糖含有組成物
US4824943A (en) * 1986-03-05 1989-04-25 Takeda Chemical Industries, Ltd. Inosose derivatives and production thereof
US4898986A (en) * 1986-09-09 1990-02-06 Takeda Chemical Industries, Ltd. Inosose derivatives, production and use thereof
ATE86853T1 (de) * 1988-08-22 1993-04-15 Takeda Chemical Industries Ltd Alpha-glucosidaseinhibitor zur foerderung der calciumabsorption.
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TW589174B (en) * 1997-12-10 2004-06-01 Takeda Chemical Industries Ltd Agent for treating high-risk impaired glucose tolerance
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US7262318B2 (en) * 2004-03-10 2007-08-28 Pfizer, Inc. Substituted heteroaryl- and phenylsulfamoyl compounds
WO2005092834A1 (en) * 2004-03-29 2005-10-06 Ranbaxy Laboratories Limited Processes for the purification of voglibose and intermediates thereof
US20050288340A1 (en) * 2004-06-29 2005-12-29 Pfizer Inc Substituted heteroaryl- and phenylsulfamoyl compounds
CN1736977B (zh) * 2004-08-16 2010-05-12 深圳太太药业有限公司 结晶形态的(+)-(1s,2s,3s,4r,5r)-1-氨基-5-羟甲基-n-2-(1,3-二羟丙基)-2,3,4-环己三醇及其制备方法
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CN1806796B (zh) * 2005-01-17 2011-10-05 深圳太太药业有限公司 含有维力波糖的药物组合物及其制备方法和应用
KR100956490B1 (ko) * 2005-05-27 2010-05-07 주식회사유한양행 신규 탈할로겐화제를 이용한 슈도-아미노슈가의 제조방법
KR101136961B1 (ko) 2005-08-04 2012-04-19 코오롱생명과학 주식회사 발리올아민의 제조방법
US7741317B2 (en) 2005-10-21 2010-06-22 Bristol-Myers Squibb Company LXR modulators
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US7888376B2 (en) 2005-11-23 2011-02-15 Bristol-Myers Squibb Company Heterocyclic CETP inhibitors
WO2008070496A2 (en) 2006-12-01 2008-06-12 Bristol-Myers Squibb Company N- ( (3-benzyl) -2, 2- (bis-phenyl) -propan-1-amine derivatives as cetp inhibitors for the treatment of atherosclerosis and cardiovascular diseases
CN101765433A (zh) 2007-03-12 2010-06-30 Zadec私人有限责任公司 一种抗糖尿病的红灌木提取物
CN101772513B (zh) 2007-06-04 2013-11-13 协同医药品公司 有效用于胃肠功能紊乱、炎症、癌症和其他疾病治疗的鸟苷酸环化酶激动剂
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
WO2009006613A1 (en) * 2007-07-03 2009-01-08 Children's Hospital & Research Center At Oakland Polysialic acid derivatives, methods of production, and uses in enhancing cancer antigen production and targeting
JP5702600B2 (ja) * 2007-07-03 2015-04-15 チルドレンズ ホスピタル アンド リサーチ センター アット オークランド オリゴシアル酸誘導体、製造方法および免疫学的使用
WO2009006591A1 (en) * 2007-07-03 2009-01-08 Children's Hospital & Research Center At Oakland Inhibitors of polysialic acid de-n-acetylase and methods for using the same
US20090011060A1 (en) * 2007-07-06 2009-01-08 Peter Koepke Campsiandra angustifolia extract and methods of extracting and using such extract
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EP2809311A1 (de) 2012-01-31 2014-12-10 Mahmut Bilgic Brausetablettenformulierungen mit einer kombination aus voglibose und metformin
WO2013133685A1 (en) 2012-03-09 2013-09-12 Biotropics Malaysia Berhad Extract formulations of rhodamnia cinerea and uses thereof
JP2016514671A (ja) 2013-03-15 2016-05-23 シナジー ファーマシューティカルズ インコーポレイテッド グアニル酸シクラーゼのアゴニストおよびその使用
CN103254094B (zh) * 2013-03-15 2015-08-19 浙江医药股份有限公司新昌制药厂 一种(-)-有效霉醇胺五乙酸酯的合成方法
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CN113574055A (zh) 2019-01-18 2021-10-29 阿斯利康(瑞典)有限公司 Pcsk9抑制剂及其使用方法
CN111748000B (zh) * 2019-03-29 2022-05-20 沈阳药科大学 3-脱氧-5-羟基-1-氨基碳糖类化合物及其用途
CN110511152B (zh) * 2019-09-18 2020-11-03 无锡富泽药业有限公司 一种伏格列波糖杂质i盐酸盐的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4062950A (en) 1973-09-22 1977-12-13 Bayer Aktiengesellschaft Amino sugar derivatives
CA1121290A (en) 1978-02-14 1982-04-06 Yasuji Suhara Amino sugar derivatives
EP0056194B1 (de) * 1981-01-05 1984-09-12 Takeda Chemical Industries, Ltd. N-substituierte Pseudo-Aminozucker, ihre Herstellung und Verwendung

Also Published As

Publication number Publication date
CA1184181A (en) 1985-03-19
EP0056194B1 (de) 1984-09-12
EP0056194A1 (de) 1982-07-21
US4803303A (en) 1989-02-07
MX9202937A (es) 1992-06-30
US4777294A (en) 1988-10-11
US4701559A (en) 1987-10-20

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