DE3135814A1 - Verfahren und vorrichtung zur selektiven extrakorporalen praezipitation von low density lipoproteinen aus vollserum oder plasma - Google Patents

Verfahren und vorrichtung zur selektiven extrakorporalen praezipitation von low density lipoproteinen aus vollserum oder plasma

Info

Publication number
DE3135814A1
DE3135814A1 DE19813135814 DE3135814A DE3135814A1 DE 3135814 A1 DE3135814 A1 DE 3135814A1 DE 19813135814 DE19813135814 DE 19813135814 DE 3135814 A DE3135814 A DE 3135814A DE 3135814 A1 DE3135814 A1 DE 3135814A1
Authority
DE
Germany
Prior art keywords
pump
container
buffer
filter
plasma
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19813135814
Other languages
German (de)
English (en)
Inventor
Dieter 3508 Melsungen Rath
Gerhard Dr. 3501 Fuldabrück-Dörnhagen Roßkopf
Dietrich Professor 3400 Göttingen Seidel
Heinrich Dr. 3401 Waake Wieland
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
B Braun Melsungen AG
Original Assignee
B Braun Melsungen AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by B Braun Melsungen AG filed Critical B Braun Melsungen AG
Priority to DE19813135814 priority Critical patent/DE3135814A1/de
Priority to EP85109471A priority patent/EP0174478B1/de
Priority to AT85109471T priority patent/ATE70367T1/de
Priority to DE8282108259T priority patent/DE3276390D1/de
Priority to AT85109470T priority patent/ATE53499T1/de
Priority to DE8585109470T priority patent/DE3280188D1/de
Priority to EP82108259A priority patent/EP0074610B1/de
Priority to EP85109470A priority patent/EP0180720B1/de
Priority to DE85109471T priority patent/DE3280382D1/de
Priority to AT82108259T priority patent/ATE27367T1/de
Priority to ZA826627A priority patent/ZA826627B/xx
Priority to ES515595A priority patent/ES8400826A1/es
Priority to JP57158724A priority patent/JPS5858469A/ja
Publication of DE3135814A1 publication Critical patent/DE3135814A1/de
Priority to ES523779A priority patent/ES8404057A1/es
Priority to ES523778A priority patent/ES523778A0/es
Priority to US07/172,953 priority patent/US4923439A/en
Priority to JP1099883A priority patent/JPH0216454A/ja
Priority to JP1099884A priority patent/JPH0216455A/ja
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A61M1/3472—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration with treatment of the filtrate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A61M1/3472—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration with treatment of the filtrate
    • A61M1/3479—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration with treatment of the filtrate by dialysing the filtrate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A61M1/3472—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration with treatment of the filtrate
    • A61M1/3482—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration with treatment of the filtrate by filtrating the filtrate using another cross-flow filter, e.g. a membrane filter
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A61M1/3472—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration with treatment of the filtrate
    • A61M1/3486—Biological, chemical treatment, e.g. chemical precipitation; treatment by absorbents
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/92—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3672—Means preventing coagulation
    • A61M1/3675—Deactivation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/04—Liquids
    • A61M2202/0413—Blood
    • A61M2202/0456—Lipoprotein
    • A61M2202/046—Low-density lipoprotein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/75—General characteristics of the apparatus with filters
    • A61M2205/7554—General characteristics of the apparatus with filters with means for unclogging or regenerating filters

Landscapes

  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Anesthesiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Urology & Nephrology (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Endocrinology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DE19813135814 1981-09-10 1981-09-10 Verfahren und vorrichtung zur selektiven extrakorporalen praezipitation von low density lipoproteinen aus vollserum oder plasma Withdrawn DE3135814A1 (de)

Priority Applications (18)

Application Number Priority Date Filing Date Title
DE19813135814 DE3135814A1 (de) 1981-09-10 1981-09-10 Verfahren und vorrichtung zur selektiven extrakorporalen praezipitation von low density lipoproteinen aus vollserum oder plasma
AT82108259T ATE27367T1 (de) 1981-09-10 1982-09-08 Verfahren zur selektiven extrakorporalen praezipitation von low density lipoproteinen aus vollserum oder plasma.
AT85109471T ATE70367T1 (de) 1981-09-10 1982-09-08 Verfahren zur selektiven extrakorporalen praezipitation von low density lipoproteinen aus vollserum oder plasma.
DE8282108259T DE3276390D1 (en) 1981-09-10 1982-09-08 Method for the selective extracorporeal precipitation of low-density lipoproteins from serum or plasma
AT85109470T ATE53499T1 (de) 1981-09-10 1982-09-08 Vorrichtung zur selektiven extrakorporalen praezipation von low density lipoprotenen aus vollserum oder plasma.
DE8585109470T DE3280188D1 (de) 1981-09-10 1982-09-08 Vorrichtung zur selektiven extrakorporalen praezipation von low density lipoprotenen aus vollserum oder plasma.
EP82108259A EP0074610B1 (de) 1981-09-10 1982-09-08 Verfahren zur selektiven extrakorporalen Präzipitation von Low Density Lipoproteinen aus Vollserum oder Plasma
EP85109470A EP0180720B1 (de) 1981-09-10 1982-09-08 Vorrichtung zur selektiven extrakorporalen Präzipation von Low Density Lipoprotenen aus Vollserum oder Plasma
DE85109471T DE3280382D1 (enExample) 1981-09-10 1982-09-08
EP85109471A EP0174478B1 (de) 1981-09-10 1982-09-08 Verfahren zur selektiven extrakorporalen Präzipitation von Low Density Lipoproteinen aus Vollserum oder Plasma
ZA826627A ZA826627B (en) 1981-09-10 1982-09-09 Process and apparatus for the selective extracorporeal precipitation of low density lipoproteins from whole serum or plasma
ES515595A ES8400826A1 (es) 1981-09-10 1982-09-09 "procedimiento para la precipitacion extracorporea selectiva de lipoproteinas de baja densidad o b-lipoproteinas".
JP57158724A JPS5858469A (ja) 1981-09-10 1982-09-10 低密度リポ蛋白質の選択的体外沈殿法
ES523779A ES8404057A1 (es) 1981-09-10 1983-07-01 Procedimiento para la precipitacion extracorporea selectiva de lipoproteinas de baja densidad o b-lipoproteinas
ES523778A ES523778A0 (es) 1981-09-10 1983-07-01 Dispositivo para la precipitacion extracorporea de componentes de la sangre
US07/172,953 US4923439A (en) 1981-09-10 1988-03-23 Process for the selective extracorporeal precipitation of low-density lipoproteins from whole serum or plasma
JP1099883A JPH0216454A (ja) 1981-09-10 1989-04-18 血液成分の体外沈澱装置
JP1099884A JPH0216455A (ja) 1981-09-10 1989-04-18 低密度リポ蛋白質の選択的体外沈澱法

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19813135814 DE3135814A1 (de) 1981-09-10 1981-09-10 Verfahren und vorrichtung zur selektiven extrakorporalen praezipitation von low density lipoproteinen aus vollserum oder plasma

Publications (1)

Publication Number Publication Date
DE3135814A1 true DE3135814A1 (de) 1983-03-24

Family

ID=6141275

Family Applications (2)

Application Number Title Priority Date Filing Date
DE19813135814 Withdrawn DE3135814A1 (de) 1981-09-10 1981-09-10 Verfahren und vorrichtung zur selektiven extrakorporalen praezipitation von low density lipoproteinen aus vollserum oder plasma
DE85109471T Expired - Fee Related DE3280382D1 (enExample) 1981-09-10 1982-09-08

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE85109471T Expired - Fee Related DE3280382D1 (enExample) 1981-09-10 1982-09-08

Country Status (3)

Country Link
JP (1) JPS5858469A (enExample)
DE (2) DE3135814A1 (enExample)
ZA (1) ZA826627B (enExample)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3422407A1 (de) * 1984-06-16 1986-03-06 B. Braun Melsungen Ag, 3508 Melsungen Verwendung von heparinderivaten zur selektiven extrakorporalen praezipitation von low-density-lipoproteinen aus vollserum oder plasma
DE19515554A1 (de) * 1995-04-27 1996-10-31 Braun Melsungen Ag Verfahren und Vorrichtung zur simultanen extrakorporalen Elimination von Tumor-Nekrose-Faktor alpha und bakteriellen Lipopolysacchariden aus Vollblut oder/und Blutplasma
EP0705845A3 (de) * 1994-10-05 1999-04-07 B. Braun Melsungen Ag Verfahren zur simultanen Entfernung von Tumor-Nekrose-Faktor alpha und bakteriellen Lipopolysacchariden aus einer wässrigen Flüssigkeit
DE102004054747A1 (de) * 2004-11-12 2006-05-24 Fresenius Medical Care Deutschland Gmbh Verfahren und Vorrichtung zur Abreicherung wenigstens einer Komponente eines fluiden Mediums
WO2021053160A1 (de) 2019-09-20 2021-03-25 B. Braun Avitum Ag Verfahren und vorrichtung zur steuerung der antikoagulation bei der extrakorporalen blutbehandlung
DE102022108772A1 (de) 2022-04-11 2023-10-12 Heinz Meise Gmbh Vorrichtung und Verfahren zur Durchführung einer Blutplasmapherese

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6342971A (ja) * 1986-08-04 1988-02-24 ユニチカ株式会社 撥水性織物の製造方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1277592B (de) * 1963-03-26 1968-09-12 Haury Chem Fab Dr Heinz Verfahren zur kolorimetrischen Bestimmung der Serum-ª‰-Lipoproteide
EP0035211A1 (de) * 1980-02-29 1981-09-09 Roche Diagnostics GmbH Verfahren und Reagens zur Bestimmung der beta-Lipoproteine (LDL)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ180199A (en) * 1976-03-04 1978-11-13 New Zealand Dev Finance Method of testing for the presence of elevated plasma liprotein concentration

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1277592B (de) * 1963-03-26 1968-09-12 Haury Chem Fab Dr Heinz Verfahren zur kolorimetrischen Bestimmung der Serum-ª‰-Lipoproteide
EP0035211A1 (de) * 1980-02-29 1981-09-09 Roche Diagnostics GmbH Verfahren und Reagens zur Bestimmung der beta-Lipoproteine (LDL)

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3422407A1 (de) * 1984-06-16 1986-03-06 B. Braun Melsungen Ag, 3508 Melsungen Verwendung von heparinderivaten zur selektiven extrakorporalen praezipitation von low-density-lipoproteinen aus vollserum oder plasma
US4908354A (en) * 1984-06-16 1990-03-13 B. Braun-Ssg Ag Process for the selective extracorporeal precipitation of low-density lipoproteins
EP0705845A3 (de) * 1994-10-05 1999-04-07 B. Braun Melsungen Ag Verfahren zur simultanen Entfernung von Tumor-Nekrose-Faktor alpha und bakteriellen Lipopolysacchariden aus einer wässrigen Flüssigkeit
DE19515554A1 (de) * 1995-04-27 1996-10-31 Braun Melsungen Ag Verfahren und Vorrichtung zur simultanen extrakorporalen Elimination von Tumor-Nekrose-Faktor alpha und bakteriellen Lipopolysacchariden aus Vollblut oder/und Blutplasma
DE19515554C2 (de) * 1995-04-27 1999-06-17 Braun Melsungen Ag Verwendung eines Mittels und Vorrichtung zur simultanen extrakorporalen Elimination von Tumor-Nekrose-Faktor alpha und bakteriellen Lipopolysacchariden aus Vollblut oder/und Blutplasma
DE102004054747A1 (de) * 2004-11-12 2006-05-24 Fresenius Medical Care Deutschland Gmbh Verfahren und Vorrichtung zur Abreicherung wenigstens einer Komponente eines fluiden Mediums
WO2021053160A1 (de) 2019-09-20 2021-03-25 B. Braun Avitum Ag Verfahren und vorrichtung zur steuerung der antikoagulation bei der extrakorporalen blutbehandlung
DE102022108772A1 (de) 2022-04-11 2023-10-12 Heinz Meise Gmbh Vorrichtung und Verfahren zur Durchführung einer Blutplasmapherese
DE102022108772B4 (de) * 2022-04-11 2024-04-25 Heinz Meise Gmbh Vorrichtung zur Durchführung einer Blutplasmapherese
AT526031A3 (de) * 2022-04-11 2024-08-15 Heinz Meise Gmbh Vorrichtung und Verfahren zur Durchführung einer Blutplasmapherese
AT526031B1 (de) * 2022-04-11 2025-03-15 Heinz Meise Gmbh Vorrichtung und Verfahren zur Durchführung einer Blutplasmapherese

Also Published As

Publication number Publication date
ZA826627B (en) 1983-10-26
JPH023466B2 (enExample) 1990-01-23
JPS5858469A (ja) 1983-04-07
DE3280382D1 (enExample) 1992-01-23

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