DE3105122C2 - Neue Piperazin-Verbindungen, Verfahren zu ihrer Herstellung und diese enthaltende Immunverstärker - Google Patents

Neue Piperazin-Verbindungen, Verfahren zu ihrer Herstellung und diese enthaltende Immunverstärker

Info

Publication number
DE3105122C2
DE3105122C2 DE3105122A DE3105122A DE3105122C2 DE 3105122 C2 DE3105122 C2 DE 3105122C2 DE 3105122 A DE3105122 A DE 3105122A DE 3105122 A DE3105122 A DE 3105122A DE 3105122 C2 DE3105122 C2 DE 3105122C2
Authority
DE
Germany
Prior art keywords
test
compounds
citrate
cancer
immune
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE3105122A
Other languages
German (de)
English (en)
Other versions
DE3105122A1 (de
Inventor
Shiyoichiro Miyahara
Yutaka Okazaki
Hiroshi Mobara Chiba Tokuda
Yoshitsugu Oomuta Fukuoka Yamada
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsui Toatsu Chemicals Inc
Original Assignee
Mitsui Toatsu Chemicals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsui Toatsu Chemicals Inc filed Critical Mitsui Toatsu Chemicals Inc
Publication of DE3105122A1 publication Critical patent/DE3105122A1/de
Application granted granted Critical
Publication of DE3105122C2 publication Critical patent/DE3105122C2/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
    • C07D295/215—Radicals derived from nitrogen analogues of carbonic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE3105122A 1980-02-15 1981-02-12 Neue Piperazin-Verbindungen, Verfahren zu ihrer Herstellung und diese enthaltende Immunverstärker Expired DE3105122C2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP1656080A JPS56127369A (en) 1980-02-15 1980-02-15 Nevel piperazine compound, its preparation and utilization

Publications (2)

Publication Number Publication Date
DE3105122A1 DE3105122A1 (de) 1981-12-10
DE3105122C2 true DE3105122C2 (de) 1985-05-15

Family

ID=11919658

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3105122A Expired DE3105122C2 (de) 1980-02-15 1981-02-12 Neue Piperazin-Verbindungen, Verfahren zu ihrer Herstellung und diese enthaltende Immunverstärker

Country Status (6)

Country Link
US (1) US4420481A (en, 2012)
JP (1) JPS56127369A (en, 2012)
DE (1) DE3105122C2 (en, 2012)
FR (1) FR2478097A1 (en, 2012)
GB (1) GB2069497B (en, 2012)
IT (1) IT1170713B (en, 2012)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3483252D1 (de) * 1983-12-05 1990-10-25 Asahi Chemical Ind Verfahren zur induktion von antitumorimmunozyten, verfahren zur herstellung von antitumorimmunozyten und durch das verfahren hergestellte antitumorimmunozyten.
US4668687A (en) * 1984-07-23 1987-05-26 Bristol-Myers Company Psychogeriatric 1-(2-pyrimidinyl)piperazinyl derivatives of 1-pyrrolidin-2-ones
US4628052A (en) * 1985-05-28 1986-12-09 Peat Raymond F Pharmaceutical compositions containing dehydroepiandrosterone and other anesthetic steroids in the treatment of arthritis and other joint disabilities
US4842862A (en) * 1986-07-03 1989-06-27 International Minerals & Chemical Corp. Immunostimulating agents
USD662297S1 (en) 2011-05-06 2012-06-26 Deckers Outdoor Corporation Heel wrap

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE506694A (en, 2012) *
GB631685A (en) * 1946-04-12 1949-11-08 American Cyanamid Co Improvements in or relating to the preparation of piperazine mono carboxamides
US3133067A (en) * 1959-01-30 1964-05-12 Sterling Drug Inc 1-monocarbocyclic aryl-4-thiocarbam-ylpiperazines and intermediates and processes therefor
US3250771A (en) * 1962-12-17 1966-05-10 Geigy Chem Corp 5-monocarbocyclic aryl-n-lower alkyl-2-pyrrolidine carboxylic acid, esters, amides and derivatives thereof
US3509171A (en) * 1967-09-14 1970-04-28 Robins Co Inc A H 3-amino-1-carbamyl and thiocarbamyl pyrrolidines
BE789830A (fr) * 1971-10-09 1973-02-01 Asta Werke Ag Chem Fab Procede de preparation de nouveaux derives cycliques d'uree et de leurssels avec des acides pharmacologiquement acceptables
US3895111A (en) * 1973-06-27 1975-07-15 American Cyanamid Co Asthma treatment by inhalation of micronized N,N-diethyl-4-methyl-1-piperazinecarboxamide pamoate
JPS6035055B2 (ja) * 1978-12-07 1985-08-12 富士写真フイルム株式会社 ハロゲン化銀写真乳剤

Also Published As

Publication number Publication date
DE3105122A1 (de) 1981-12-10
FR2478097A1 (fr) 1981-09-18
JPS56127369A (en) 1981-10-06
IT8147787A0 (it) 1981-02-13
IT1170713B (it) 1987-06-03
JPS6332764B2 (en, 2012) 1988-07-01
IT8147787A1 (it) 1982-08-13
GB2069497A (en) 1981-08-26
US4420481A (en) 1983-12-13
GB2069497B (en) 1984-08-22
FR2478097B1 (en, 2012) 1984-02-17

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Legal Events

Date Code Title Description
8110 Request for examination paragraph 44
D2 Grant after examination
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee