DE3040168A1 - Vorrichtung zum messen von klinischen notkontrollmerkmalen des bluts - Google Patents
Vorrichtung zum messen von klinischen notkontrollmerkmalen des blutsInfo
- Publication number
- DE3040168A1 DE3040168A1 DE19803040168 DE3040168A DE3040168A1 DE 3040168 A1 DE3040168 A1 DE 3040168A1 DE 19803040168 DE19803040168 DE 19803040168 DE 3040168 A DE3040168 A DE 3040168A DE 3040168 A1 DE3040168 A1 DE 3040168A1
- Authority
- DE
- Germany
- Prior art keywords
- blood
- sensor
- electrode
- sampler
- computer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 239000008280 blood Substances 0.000 title claims abstract description 51
- 210000004369 blood Anatomy 0.000 title claims abstract description 51
- 208000024891 symptom Diseases 0.000 title abstract 2
- 239000003792 electrolyte Substances 0.000 claims abstract description 19
- 239000000523 sample Substances 0.000 claims description 50
- 239000000306 component Substances 0.000 claims description 30
- 239000007789 gas Substances 0.000 claims description 19
- 239000000470 constituent Substances 0.000 claims description 17
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims description 10
- 238000000502 dialysis Methods 0.000 claims description 10
- 239000001301 oxygen Substances 0.000 claims description 10
- 229910052760 oxygen Inorganic materials 0.000 claims description 10
- 238000000855 fermentation Methods 0.000 claims description 6
- 230000004151 fermentation Effects 0.000 claims description 6
- 239000012528 membrane Substances 0.000 claims description 6
- BHPQYMZQTOCNFJ-UHFFFAOYSA-N Calcium cation Chemical compound [Ca+2] BHPQYMZQTOCNFJ-UHFFFAOYSA-N 0.000 claims description 5
- 229910001424 calcium ion Inorganic materials 0.000 claims description 5
- 238000002848 electrochemical method Methods 0.000 claims description 5
- 229910001414 potassium ion Inorganic materials 0.000 claims description 5
- 229910001415 sodium ion Inorganic materials 0.000 claims description 5
- NPYPAHLBTDXSSS-UHFFFAOYSA-N Potassium ion Chemical compound [K+] NPYPAHLBTDXSSS-UHFFFAOYSA-N 0.000 claims description 4
- FKNQFGJONOIPTF-UHFFFAOYSA-N Sodium cation Chemical compound [Na+] FKNQFGJONOIPTF-UHFFFAOYSA-N 0.000 claims description 4
- 239000012503 blood component Substances 0.000 claims description 4
- QGZKDVFQNNGYKY-UHFFFAOYSA-O Ammonium Chemical compound [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 claims description 3
- BVKZGUZCCUSVTD-UHFFFAOYSA-M Bicarbonate Chemical compound OC([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-M 0.000 claims description 3
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 claims description 3
- 230000009429 distress Effects 0.000 claims 3
- 238000011156 evaluation Methods 0.000 claims 3
- 239000011244 liquid electrolyte Substances 0.000 claims 1
- 239000000126 substance Substances 0.000 abstract 1
- 238000005259 measurement Methods 0.000 description 7
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 6
- 239000012086 standard solution Substances 0.000 description 6
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 5
- 239000007853 buffer solution Substances 0.000 description 5
- 239000008103 glucose Substances 0.000 description 5
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 4
- 108010015776 Glucose oxidase Proteins 0.000 description 4
- 239000004366 Glucose oxidase Substances 0.000 description 4
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 description 4
- 238000010586 diagram Methods 0.000 description 4
- 229940116332 glucose oxidase Drugs 0.000 description 4
- 235000019420 glucose oxidase Nutrition 0.000 description 4
- 239000000243 solution Substances 0.000 description 4
- 238000004458 analytical method Methods 0.000 description 3
- 201000010099 disease Diseases 0.000 description 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 3
- 238000011144 upstream manufacturing Methods 0.000 description 3
- RGHNJXZEOKUKBD-SQOUGZDYSA-N D-gluconic acid Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O RGHNJXZEOKUKBD-SQOUGZDYSA-N 0.000 description 2
- 108010046334 Urease Proteins 0.000 description 2
- 239000001569 carbon dioxide Substances 0.000 description 2
- 229910002092 carbon dioxide Inorganic materials 0.000 description 2
- DDRJAANPRJIHGJ-UHFFFAOYSA-N creatinine Chemical compound CN1CC(=O)NC1=N DDRJAANPRJIHGJ-UHFFFAOYSA-N 0.000 description 2
- 238000003745 diagnosis Methods 0.000 description 2
- 150000002500 ions Chemical class 0.000 description 2
- -1 Ammonium ions Chemical class 0.000 description 1
- 108010066906 Creatininase Proteins 0.000 description 1
- RGHNJXZEOKUKBD-UHFFFAOYSA-N D-gluconic acid Natural products OCC(O)C(O)C(O)C(O)C(O)=O RGHNJXZEOKUKBD-UHFFFAOYSA-N 0.000 description 1
- 229910021607 Silver chloride Inorganic materials 0.000 description 1
- 108010092464 Urate Oxidase Proteins 0.000 description 1
- LEHOTFFKMJEONL-UHFFFAOYSA-N Uric Acid Chemical compound N1C(=O)NC(=O)C2=C1NC(=O)N2 LEHOTFFKMJEONL-UHFFFAOYSA-N 0.000 description 1
- TVWHNULVHGKJHS-UHFFFAOYSA-N Uric acid Natural products N1C(=O)NC(=O)C2NC(=O)NC21 TVWHNULVHGKJHS-UHFFFAOYSA-N 0.000 description 1
- PNNCWTXUWKENPE-UHFFFAOYSA-N [N].NC(N)=O Chemical compound [N].NC(N)=O PNNCWTXUWKENPE-UHFFFAOYSA-N 0.000 description 1
- 238000004159 blood analysis Methods 0.000 description 1
- 239000011575 calcium Substances 0.000 description 1
- UBAZGMLMVVQSCD-UHFFFAOYSA-N carbon dioxide;molecular oxygen Chemical compound O=O.O=C=O UBAZGMLMVVQSCD-UHFFFAOYSA-N 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 239000012141 concentrate Substances 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 239000000356 contaminant Substances 0.000 description 1
- 229940109239 creatinine Drugs 0.000 description 1
- 238000009792 diffusion process Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 239000008151 electrolyte solution Substances 0.000 description 1
- 239000000174 gluconic acid Substances 0.000 description 1
- 235000012208 gluconic acid Nutrition 0.000 description 1
- 229910052739 hydrogen Inorganic materials 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- WABPQHHGFIMREM-UHFFFAOYSA-N lead(0) Chemical compound [Pb] WABPQHHGFIMREM-UHFFFAOYSA-N 0.000 description 1
- 210000002966 serum Anatomy 0.000 description 1
- HKZLPVFGJNLROG-UHFFFAOYSA-M silver monochloride Chemical compound [Cl-].[Ag+] HKZLPVFGJNLROG-UHFFFAOYSA-M 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
- AYTGUZPQPXGYFS-UHFFFAOYSA-N urea nitrate Chemical compound NC(N)=O.O[N+]([O-])=O AYTGUZPQPXGYFS-UHFFFAOYSA-N 0.000 description 1
- 229940116269 uric acid Drugs 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/155—Devices specially adapted for continuous or multiple sampling, e.g. at predetermined intervals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
- A61B5/14539—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring pH
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/150007—Details
- A61B5/150015—Source of blood
- A61B5/15003—Source of blood for venous or arterial blood
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G01N33/49—Blood
- G01N33/492—Determining multiple analytes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Biophysics (AREA)
- Pathology (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medical Informatics (AREA)
- Heart & Thoracic Surgery (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Surgery (AREA)
- Chemical & Material Sciences (AREA)
- Food Science & Technology (AREA)
- Urology & Nephrology (AREA)
- Ecology (AREA)
- Medicinal Chemistry (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Optics & Photonics (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP13902879A JPS5663259A (en) | 1979-10-26 | 1979-10-26 | Measuring device for blood emergent test item |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE3040168A1 true DE3040168A1 (de) | 1981-05-14 |
Family
ID=15235771
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE19803040168 Withdrawn DE3040168A1 (de) | 1979-10-26 | 1980-10-24 | Vorrichtung zum messen von klinischen notkontrollmerkmalen des bluts |
Country Status (2)
| Country | Link |
|---|---|
| JP (1) | JPS5663259A (enrdf_load_stackoverflow) |
| DE (1) | DE3040168A1 (enrdf_load_stackoverflow) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2591747A1 (fr) * | 1985-11-15 | 1987-06-19 | Smithkline Diagnostics Inc | Analyseur medical a electrodes enzymatiques ou a selectivite ionique et procede d'utilisation |
| EP0273258A1 (de) * | 1986-12-22 | 1988-07-06 | Siemens Aktiengesellschaft | Anordnung zur Untersuchung eines flüssigen Mediums und Verfahren zum Betrieb der Anordnung |
| WO1989000397A1 (en) * | 1987-07-09 | 1989-01-26 | Avl Ag | Device for withdrawal of body fluids |
| FR3074911A1 (fr) * | 2017-12-11 | 2019-06-14 | Vitea Engineering S.R.L | Dispositif et procede d'analyse de compositions liquides, notamment d'echantillons de liquides d'origine biologique pour la determination notamment des electrolytes |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5784345A (en) * | 1980-11-15 | 1982-05-26 | Toyobo Co Ltd | 3-items analyzer |
| JPS57189056A (en) * | 1981-05-15 | 1982-11-20 | Toa Denpa Kogyo Kk | Multiitem analyzing method of blood |
| JPS58202865A (ja) * | 1982-05-21 | 1983-11-26 | Toyobo Co Ltd | 多項目分析計 |
| JPH0640814B2 (ja) * | 1982-07-24 | 1994-06-01 | 株式会社東芝 | 自動化学分析装置 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3556950A (en) * | 1966-07-15 | 1971-01-19 | Ibm | Method and apparatus for automatic electrochemical analysis |
-
1979
- 1979-10-26 JP JP13902879A patent/JPS5663259A/ja active Granted
-
1980
- 1980-10-24 DE DE19803040168 patent/DE3040168A1/de not_active Withdrawn
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2591747A1 (fr) * | 1985-11-15 | 1987-06-19 | Smithkline Diagnostics Inc | Analyseur medical a electrodes enzymatiques ou a selectivite ionique et procede d'utilisation |
| EP0273258A1 (de) * | 1986-12-22 | 1988-07-06 | Siemens Aktiengesellschaft | Anordnung zur Untersuchung eines flüssigen Mediums und Verfahren zum Betrieb der Anordnung |
| US4841974A (en) * | 1986-12-22 | 1989-06-27 | Siemens Aktiengesellschaft | Apparatus and method for the examination of a liquid medium |
| WO1989000397A1 (en) * | 1987-07-09 | 1989-01-26 | Avl Ag | Device for withdrawal of body fluids |
| FR3074911A1 (fr) * | 2017-12-11 | 2019-06-14 | Vitea Engineering S.R.L | Dispositif et procede d'analyse de compositions liquides, notamment d'echantillons de liquides d'origine biologique pour la determination notamment des electrolytes |
| WO2019115526A1 (fr) * | 2017-12-11 | 2019-06-20 | Neovitea | Dispositif et procede d'analyse de compositions liquides, notamment d'echantillons de liquides d'origine biologique pour la determination notamment des electrolytes |
| EP3724665A1 (fr) * | 2017-12-11 | 2020-10-21 | Neovitea | Dispositif et procede d'analyse de compositions liquides, notamment d'echantillons de liquides d'origine biologique pour la determination notamment des electrolytes |
| US12050229B2 (en) | 2017-12-11 | 2024-07-30 | Neovitea | Device and method for analyzing liquid compositions, particularly samples of liquids of biological origin particularly for determining electrolytes |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6325301B2 (enrdf_load_stackoverflow) | 1988-05-25 |
| JPS5663259A (en) | 1981-05-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8110 | Request for examination paragraph 44 | ||
| 8130 | Withdrawal |