DE3025078A1 - Gereinigtes immunserumglobulin- praeparat - Google Patents

Gereinigtes immunserumglobulin- praeparat

Info

Publication number
DE3025078A1
DE3025078A1 DE19803025078 DE3025078A DE3025078A1 DE 3025078 A1 DE3025078 A1 DE 3025078A1 DE 19803025078 DE19803025078 DE 19803025078 DE 3025078 A DE3025078 A DE 3025078A DE 3025078 A1 DE3025078 A1 DE 3025078A1
Authority
DE
Germany
Prior art keywords
pka
factor xii
preparation
isg
activity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
DE19803025078
Other languages
German (de)
English (en)
Other versions
DE3025078C2 (https=
Inventor
Timothy R Zuffi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Corp
Original Assignee
Cutter Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cutter Laboratories Inc filed Critical Cutter Laboratories Inc
Publication of DE3025078A1 publication Critical patent/DE3025078A1/de
Application granted granted Critical
Publication of DE3025078C2 publication Critical patent/DE3025078C2/de
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065—Purification, fragmentation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE19803025078 1979-07-16 1980-07-02 Gereinigtes immunserumglobulin- praeparat Granted DE3025078A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/057,880 US4272521A (en) 1979-07-16 1979-07-16 Purified immune serum globulin

Publications (2)

Publication Number Publication Date
DE3025078A1 true DE3025078A1 (de) 1981-02-05
DE3025078C2 DE3025078C2 (https=) 1993-02-18

Family

ID=22013311

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19803025078 Granted DE3025078A1 (de) 1979-07-16 1980-07-02 Gereinigtes immunserumglobulin- praeparat

Country Status (3)

Country Link
US (1) US4272521A (https=)
JP (1) JPS5616416A (https=)
DE (1) DE3025078A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110339209A (zh) * 2019-07-18 2019-10-18 上海泰坦科技股份有限公司 一种去甲状腺结合蛋白的小牛血清的制备方法

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE32011E (en) * 1981-12-14 1985-10-22 Scripps Clinic And Research Foundation Ultrapurification of factor VIII using monoclonal antibodies
US4639513A (en) * 1984-02-02 1987-01-27 Cuno Inc. Intravenously injectable immunoglobulin G (IGG) and method for producing same
US5165938A (en) * 1984-11-29 1992-11-24 Regents Of The University Of Minnesota Wound healing agents derived from platelets
US4590002A (en) * 1984-12-10 1986-05-20 Ortho Diagnostic Systems, Inc. Methods for preparation of highly purified, gamma globulins free of hepatitis-B-virus infectivity
JPH0662435B2 (ja) * 1986-02-28 1994-08-17 株式会社ミドリ十字 免疫グロブリンの製造方法
JPH0662436B2 (ja) * 1986-05-19 1994-08-17 株式会社ミドリ十字 静注用免疫グロブリン製剤の製造方法
US4911910A (en) * 1986-11-25 1990-03-27 Biotech Research Labs, Inc. Purified equine immunologlobulins and method of use thereof
US5157113A (en) * 1987-08-10 1992-10-20 Miles Inc. Removal of nucleic acids from monoclonal antibody preparations
AT391810B (de) * 1988-02-26 1990-12-10 Immuno Ag Verwendung von chymotrypsin zum unwirksammachen des praekallikrein-aktivators
US6979307B2 (en) * 1997-06-24 2005-12-27 Cascade Medical Enterprises Llc Systems and methods for preparing autologous fibrin glue
US7745106B2 (en) * 1997-06-24 2010-06-29 Cascade Medical Enterprises, Llc Methods and devices for separating liquid components
US20080199513A1 (en) * 1997-06-24 2008-08-21 Cascade Medical Enterprises, Llc Systems and methods for preparing autologous fibrin glue
DK2270044T3 (en) * 1998-06-09 2015-01-26 Csl Behring Ag Liquid immunoglobulin G (IgG) product
WO1999066797A1 (en) 1998-06-22 1999-12-29 Worden Charles E Enriched platelet wound healant
FR2824568B1 (fr) * 2001-05-11 2004-04-09 Lab Francais Du Fractionnement Procede de preparation de concentres d'immunoglobulines humaines a usage therapeutique
EP1890820A4 (en) * 2005-03-22 2012-04-11 Cascade Medical Entpr Llc SYSTEMS AND METHOD FOR PRODUCING MEMBRANES
ES2488542T3 (es) 2008-12-22 2014-08-27 F. Hoffmann-La Roche Ag Purificación de inmunoglobulinas
FR2974301B1 (fr) * 2011-04-20 2013-08-23 Lab Francais Du Fractionnement Procede de preparation d'un produit plasmatique deplete en un ou plusieurs facteurs thrombogenes
IL212911A0 (en) * 2011-05-16 2011-07-31 Omrix Biopharmaceuticals Ltd Immunoglobulin reduced in thrombogenic contaminants and preparation thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3717708A (en) * 1968-10-24 1973-02-20 Cutter Lab Blood coagulation complex
US3869436A (en) * 1971-06-01 1975-03-04 Statens Bakteriologiska Lab Method for fractionating plasma proteins using peg and ion-exchangers
US4136094A (en) * 1977-08-31 1979-01-23 The Regents Of The University Of Minnesota Preparation of intravenous human and animal gamma globulins and isolation of albumin

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL43643A (en) * 1972-11-27 1976-10-31 Baxter Laboratories Inc Method for production of gamma globulin
US4137307A (en) * 1973-11-15 1979-01-30 The Green Cross Corporation Process for preparing haptoglobin aqueous solution using strong anion exchanger
CA1064396A (en) 1975-02-18 1979-10-16 Myer L. Coval Fractional precipitation of gamma globulin with polyethylene glycol
US4126605A (en) * 1975-12-29 1978-11-21 Plasmesco Ag Process of improving the compatibility of gamma globulins
US4165370A (en) * 1976-05-21 1979-08-21 Coval M L Injectable gamma globulin
US4075193A (en) * 1976-11-26 1978-02-21 Parke, Davis & Company Process for producing intravenous immune globulin
US4124576A (en) * 1976-12-03 1978-11-07 Coval M L Method of producing intravenously injectable gamma globulin

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3717708A (en) * 1968-10-24 1973-02-20 Cutter Lab Blood coagulation complex
US3869436A (en) * 1971-06-01 1975-03-04 Statens Bakteriologiska Lab Method for fractionating plasma proteins using peg and ion-exchangers
US4136094A (en) * 1977-08-31 1979-01-23 The Regents Of The University Of Minnesota Preparation of intravenous human and animal gamma globulins and isolation of albumin

Non-Patent Citations (13)

* Cited by examiner, † Cited by third party
Title
"Protides of the Biological Fluids, 17th Colloquium 1969, ed. H. Peeters, Pergamon Press Ltd., First Edition, 1970" *
Campbell et al.: Methods in Immunology", W.A. Benjamin, Inc., New York und Amsterdam *
Fahey und Horbett, "Human Gamma Globulin Fractionation on Anion Exchange Cellulose Columns"J. Biol. Chem. 234, 2645-2651 *
HARPER, H.A. et.al.: Physiologische Chemie, Springer, Berlin 1975, S. 680 *
HRISTOVA: "Application of DEAE-Sephadex A-50 for Additional Purification of Antitoxic Sera", Z. Immunitätsforsch., Allergie Klin. Immunol. 135, 439-448
MOGI, et.al.: "DEAE-Cellulose Batch Production of Immunoglobulin G (IgG) from Antilymphocyte Serum (ALS)", Laryngoscope 82, 998-106
MOZES und SELA: "Resolution of Mouse and Human Immunoglobulin G into two Fractions by Chromatography on Diethylaminoethyl-Sephadex. Relation of Mouse Antibody Type to the Antigen Charge", Israel J. Med. Sci. 5, 267-270
RADEMECKER et.al.: "Effect of Absorption of IgG with Insolubilized Antiserum on Reaginic Activity of DEAE-Serum Fractions", Int. Arch. Allergy 37, 301-310
SGOURIS et.al.: "A Procedure for Preparing for Preparing Immunoglobulin G from Human and Monkes Blood", Transfusion 6, 146-149
SUZUKI, T. et.al.: Methods in Enzymologie, Bd. 34, Academic Press, New York 1974, S. 432-435 *
Tatnoff und Davie, "The Purification of Activated Hageman Factor (Activated Factor XII) " Biochemistry 1, 967-974 *
Vaerman et.al.: "Studies of the Immune Globulins of Human Serum. I A Method for the Simultaneous Isolation of the three Immune Globulins (??s??s?' ??1??M? and ??1??A?) from Individual Small Serum Samples", J. Immunol. 91, 7-10
Vaerman et.al.: "Studies of the Immune Globulins of Human Serum. I A Method for the Simultaneous Isolation of the three Immune Globulins (gamma¶s¶¶s¶' gamma¶1¶¶M¶ and gamma¶1¶¶A¶) from Individual Small Serum Samples", J. Immunol. 91, 7-10 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110339209A (zh) * 2019-07-18 2019-10-18 上海泰坦科技股份有限公司 一种去甲状腺结合蛋白的小牛血清的制备方法
CN110339209B (zh) * 2019-07-18 2023-06-06 上海泰坦科技股份有限公司 一种去甲状腺结合蛋白的小牛血清的制备方法

Also Published As

Publication number Publication date
DE3025078C2 (https=) 1993-02-18
JPS5616416A (en) 1981-02-17
JPH0133450B2 (https=) 1989-07-13
US4272521A (en) 1981-06-09

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Legal Events

Date Code Title Description
8110 Request for examination paragraph 44
8127 New person/name/address of the applicant

Owner name: MILES, INC., ELKHART, IND., US

8128 New person/name/address of the agent

Representative=s name: MUELLER, G., DIPL.-CHEM. DR.RER.NAT., PAT.-ASS., 5

8125 Change of the main classification

Ipc: A61K 37/04

D2 Grant after examination
8331 Complete revocation