DE3005605A1 - Verfahren und vorrichtung zur abtrennung von wirkstoffen aus einer zellsuspension - Google Patents

Verfahren und vorrichtung zur abtrennung von wirkstoffen aus einer zellsuspension

Info

Publication number
DE3005605A1
DE3005605A1 DE19803005605 DE3005605A DE3005605A1 DE 3005605 A1 DE3005605 A1 DE 3005605A1 DE 19803005605 DE19803005605 DE 19803005605 DE 3005605 A DE3005605 A DE 3005605A DE 3005605 A1 DE3005605 A1 DE 3005605A1
Authority
DE
Germany
Prior art keywords
cell suspension
ultrafilter
fermenter
outlet side
membrane filtration
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
DE19803005605
Other languages
German (de)
English (en)
Other versions
DE3005605C2 (enrdf_load_stackoverflow
Inventor
Helge Dr. 3400 Göttingen Böhnel
Horst S.H. Prof. Dr. 3406 Bovenden Seifert
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Seifert Horst Prof Dr Boehnel Helge Dr 340
Original Assignee
Sartorius AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sartorius AG filed Critical Sartorius AG
Priority to DE19803005605 priority Critical patent/DE3005605A1/de
Publication of DE3005605A1 publication Critical patent/DE3005605A1/de
Application granted granted Critical
Publication of DE3005605C2 publication Critical patent/DE3005605C2/de
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/08—Clostridium, e.g. Clostridium tetani
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/04—Filters; Permeable or porous membranes or plates, e.g. dialysis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/10—Separation or concentration of fermentation products
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/02—Separating microorganisms from their culture media
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Sustainable Development (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DE19803005605 1980-02-15 1980-02-15 Verfahren und vorrichtung zur abtrennung von wirkstoffen aus einer zellsuspension Granted DE3005605A1 (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DE19803005605 DE3005605A1 (de) 1980-02-15 1980-02-15 Verfahren und vorrichtung zur abtrennung von wirkstoffen aus einer zellsuspension

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19803005605 DE3005605A1 (de) 1980-02-15 1980-02-15 Verfahren und vorrichtung zur abtrennung von wirkstoffen aus einer zellsuspension

Publications (2)

Publication Number Publication Date
DE3005605A1 true DE3005605A1 (de) 1981-10-01
DE3005605C2 DE3005605C2 (enrdf_load_stackoverflow) 1988-04-21

Family

ID=6094640

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19803005605 Granted DE3005605A1 (de) 1980-02-15 1980-02-15 Verfahren und vorrichtung zur abtrennung von wirkstoffen aus einer zellsuspension

Country Status (1)

Country Link
DE (1) DE3005605A1 (enrdf_load_stackoverflow)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1986002944A1 (en) * 1984-11-07 1986-05-22 Albright & Wilson Limited Improvements relating to biotransformation reactions
FR2583060A1 (fr) * 1985-06-06 1986-12-12 Inst Francais Du Petrole Production de butanol et d'acetone par fermentation avec recyclage de la biomasse par ultrafiltration
US4692411A (en) * 1983-09-06 1987-09-08 Ghose Rabindra N Separation of specific biological cells by a biochemical filter
US4751003A (en) * 1985-05-02 1988-06-14 Henkel Kommanditgesellschaft Auf Aktien Crossflow microfiltration process for the separation of biotechnologically produced materials
FR2608170A1 (fr) * 1986-12-12 1988-06-17 Speichim Equip Ind Chimiq Nouveau procede utilisable en continu de fermentation d'un mout aqueux en vue de produire de l'ethanol et/ou une biomasse de levure
EP2330209A4 (en) * 2008-09-30 2015-04-01 Toray Industries METHOD FOR PRODUCING A CONTINUOUS CHEMICAL CULTURE SYSTEM

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102004032318B4 (de) * 2004-07-02 2015-08-20 Technische Hochschule Mittelhessen Herstellung einer konzentrierten Lösung aus biologischen Substanzen

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
NICHTS ERMITTELT *

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4692411A (en) * 1983-09-06 1987-09-08 Ghose Rabindra N Separation of specific biological cells by a biochemical filter
WO1986002944A1 (en) * 1984-11-07 1986-05-22 Albright & Wilson Limited Improvements relating to biotransformation reactions
US4751003A (en) * 1985-05-02 1988-06-14 Henkel Kommanditgesellschaft Auf Aktien Crossflow microfiltration process for the separation of biotechnologically produced materials
FR2583060A1 (fr) * 1985-06-06 1986-12-12 Inst Francais Du Petrole Production de butanol et d'acetone par fermentation avec recyclage de la biomasse par ultrafiltration
FR2608170A1 (fr) * 1986-12-12 1988-06-17 Speichim Equip Ind Chimiq Nouveau procede utilisable en continu de fermentation d'un mout aqueux en vue de produire de l'ethanol et/ou une biomasse de levure
EP0284697A1 (fr) * 1986-12-12 1988-10-05 Société pour l'Equipement des Industries Chimiques "SPEICHIM" Nouveau procédé utilisable en continu de fermentation par Saccharomyces cerevisiae d'un moût aqueux en vue de produire de l'éthanol et/ou unebiomasse de levure
EP2330209A4 (en) * 2008-09-30 2015-04-01 Toray Industries METHOD FOR PRODUCING A CONTINUOUS CHEMICAL CULTURE SYSTEM
US10428358B2 (en) 2008-09-30 2019-10-01 Toray Industries, Inc. Method of producing a chemical product

Also Published As

Publication number Publication date
DE3005605C2 (enrdf_load_stackoverflow) 1988-04-21

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Legal Events

Date Code Title Description
8110 Request for examination paragraph 44
D2 Grant after examination
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: SEIFERT, HORST, PROF. DR. BOEHNEL, HELGE, DR., 340

8339 Ceased/non-payment of the annual fee