DE2848683A1 - Verfahren und vorrichtung zum trennen von gesamtblut in mindestens drei blutkomponenten - Google Patents
Verfahren und vorrichtung zum trennen von gesamtblut in mindestens drei blutkomponentenInfo
- Publication number
- DE2848683A1 DE2848683A1 DE19782848683 DE2848683A DE2848683A1 DE 2848683 A1 DE2848683 A1 DE 2848683A1 DE 19782848683 DE19782848683 DE 19782848683 DE 2848683 A DE2848683 A DE 2848683A DE 2848683 A1 DE2848683 A1 DE 2848683A1
- Authority
- DE
- Germany
- Prior art keywords
- speed
- pump
- gear
- signal
- blood
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 210000004369 blood Anatomy 0.000 title claims description 29
- 239000008280 blood Substances 0.000 title claims description 29
- 239000012503 blood component Substances 0.000 title claims description 17
- 238000000034 method Methods 0.000 title claims description 14
- 239000000306 component Substances 0.000 claims description 46
- 210000003743 erythrocyte Anatomy 0.000 claims description 39
- 210000002381 plasma Anatomy 0.000 claims description 34
- 230000003287 optical effect Effects 0.000 claims description 31
- 210000000265 leukocyte Anatomy 0.000 claims description 21
- 230000009467 reduction Effects 0.000 claims description 16
- 230000007423 decrease Effects 0.000 claims description 15
- 210000001772 blood platelet Anatomy 0.000 claims description 12
- 239000000203 mixture Substances 0.000 claims description 12
- 238000012806 monitoring device Methods 0.000 claims description 8
- 238000000605 extraction Methods 0.000 claims description 6
- 238000012544 monitoring process Methods 0.000 claims description 6
- 230000008859 change Effects 0.000 claims description 5
- 238000005070 sampling Methods 0.000 claims description 5
- 238000009987 spinning Methods 0.000 claims description 5
- 230000003247 decreasing effect Effects 0.000 claims description 4
- 238000006073 displacement reaction Methods 0.000 claims description 4
- 239000000470 constituent Substances 0.000 claims description 3
- 230000001105 regulatory effect Effects 0.000 claims description 3
- 230000004044 response Effects 0.000 claims description 3
- 238000011109 contamination Methods 0.000 claims description 2
- 238000005259 measurement Methods 0.000 claims 2
- 230000003321 amplification Effects 0.000 claims 1
- 230000001419 dependent effect Effects 0.000 claims 1
- 238000003199 nucleic acid amplification method Methods 0.000 claims 1
- 230000002572 peristaltic effect Effects 0.000 description 7
- 239000004020 conductor Substances 0.000 description 4
- 230000000694 effects Effects 0.000 description 3
- 239000000835 fiber Substances 0.000 description 3
- 239000007788 liquid Substances 0.000 description 3
- 238000005086 pumping Methods 0.000 description 3
- 238000010586 diagram Methods 0.000 description 2
- 241000251730 Chondrichthyes Species 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 210000000601 blood cell Anatomy 0.000 description 1
- 238000005119 centrifugation Methods 0.000 description 1
- 230000001276 controlling effect Effects 0.000 description 1
- 238000012937 correction Methods 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 238000004062 sedimentation Methods 0.000 description 1
- 210000003462 vein Anatomy 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
- B04B—CENTRIFUGES
- B04B5/00—Other centrifuges
- B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
- B04B5/0442—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3693—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3693—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
- A61M1/3696—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/04—Liquids
- A61M2202/0413—Blood
- A61M2202/0439—White blood cells; Leucocytes
Landscapes
- Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Cardiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- External Artificial Organs (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/850,624 US4151844A (en) | 1977-11-11 | 1977-11-11 | Method and apparatus for separating whole blood into its components and for automatically collecting one component |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE2848683A1 true DE2848683A1 (de) | 1979-05-17 |
Family
ID=25308676
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE19782848683 Withdrawn DE2848683A1 (de) | 1977-11-11 | 1978-11-09 | Verfahren und vorrichtung zum trennen von gesamtblut in mindestens drei blutkomponenten |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US4151844A (enExample) |
| JP (1) | JPS5476814A (enExample) |
| CA (1) | CA1088035A (enExample) |
| DE (1) | DE2848683A1 (enExample) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0028842A3 (en) * | 1978-12-13 | 1981-10-28 | Antonio Ferrante | Improved medium for the separation of human blood leucocytes |
| DE3147377A1 (de) * | 1981-11-30 | 1983-06-01 | Akzo Gmbh, 5600 Wuppertal | Verfahren und vorrichtung zur extrakorporalen entfernung von an eiweisskoerpern gebundenen toxinen |
| DE4129516A1 (de) * | 1991-09-06 | 1993-03-18 | Fresenius Ag | Verfahren und vorrichtung zum trennen von blut in seine bestandteile |
Families Citing this family (73)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4216770A (en) * | 1979-02-09 | 1980-08-12 | Baxter Travenol Laboratories, Inc. | Sickle cell therapeutic treatment |
| JPS5749461A (en) * | 1980-09-10 | 1982-03-23 | Asahi Chemical Ind | Blood treating vessel, device and method for separating platelet |
| JPS5666756A (en) * | 1979-11-02 | 1981-06-05 | Asahi Chem Ind Co Ltd | Control method of centrifugal processing and its device |
| JPS5749460A (en) * | 1980-09-09 | 1982-03-23 | Asahi Chemical Ind | Blood treating vessel, device and method for separating polyplatelet blood plasma |
| US4389206A (en) * | 1980-10-09 | 1983-06-21 | Baxter Travenol Laboratories, Inc. | Centrifugal processing apparatus and rotatable processing bowl apparatus |
| US4389207A (en) * | 1981-03-16 | 1983-06-21 | Baxter Travenol Laboratories, Inc. | Rotatable bowl assembly for centrifugal processing apparatus having a bonded and prewound umbilical system |
| US4623470A (en) * | 1981-11-09 | 1986-11-18 | Helipump, Inc. | Process and apparatus for separating or fractionating fluid mixtures |
| US4531932A (en) * | 1981-11-27 | 1985-07-30 | Dideco S.P.A. | Centrifugal plasmapheresis device |
| US4458539A (en) * | 1981-12-15 | 1984-07-10 | Baxter Travenol Laboratories, Inc. | Blood fractionation apparatus having collected volume display system |
| US4481827A (en) * | 1981-12-15 | 1984-11-13 | Baxter Travenol Laboratories, Inc. | Blood fractionation apparatus having collection rate display system |
| BR8208017A (pt) * | 1981-12-15 | 1983-11-08 | Baxter Travenol Lab | Aparelhos de coleta e de processamento de fluido e de fracionamento de sangue, e sistema de fracionamento de fluido |
| US4582598A (en) * | 1981-12-15 | 1986-04-15 | Baxter Travenol Laboratories, Inc. | Replacement fluid control system for a blood fractionation apparatus and the like |
| US4533468A (en) * | 1982-12-06 | 1985-08-06 | The Broken Hill Proprietary Company Limited | Centrifugal separation method and apparatus |
| JPS6031763A (ja) * | 1983-07-29 | 1985-02-18 | オムロン株式会社 | 血液成分の自動採取装置 |
| EP0165254A1 (en) * | 1983-12-13 | 1985-12-27 | Baxter Travenol Laboratories, Inc. | Flexible disposable centrifuge system |
| US4530691A (en) * | 1983-12-13 | 1985-07-23 | Baxter Travenol Laboratories, Inc. | Centrifuge with movable mandrel |
| JPS60153869A (ja) * | 1984-01-23 | 1985-08-13 | 日立工機株式会社 | 成分採血装置用境界検知器 |
| DE3410286C2 (de) * | 1984-03-21 | 1986-01-23 | Fresenius AG, 6380 Bad Homburg | Verfahren zur Trennung von Blut sowie Vorrichtung zur Durchführung des Verfahrens |
| US4692136A (en) * | 1985-10-11 | 1987-09-08 | Cardiovascular Systems Inc. | Centrifuge |
| US4795419A (en) * | 1985-10-11 | 1989-01-03 | Kardiothor, Inc. | Centrifuge |
| US4718888A (en) * | 1986-03-10 | 1988-01-12 | Cardiovascular Systems, Inc. | Centrifuge bowl mount |
| DE3632176A1 (de) * | 1986-09-22 | 1988-04-07 | Fresenius Ag | Steuerung eines systems zur trennung der bestandteile des einem spender "in vivo" entnommenen blutes |
| US4808151A (en) * | 1987-04-27 | 1989-02-28 | E. I. Du Pont De Nemours And Company | Simplified method for the preparation of human lymphokine activated killer cells |
| US4807845A (en) * | 1987-09-30 | 1989-02-28 | Kardiothor, Inc. | Tube valve |
| DE3931471A1 (de) * | 1989-09-21 | 1991-04-11 | Fresenius Ag | Verfahren und vorrichtung zur trennung von blut mittels einer zentrifuge |
| US5112298A (en) * | 1990-06-25 | 1992-05-12 | Baxter International Inc. | Apheresis method and device |
| SE9101413L (sv) * | 1991-05-10 | 1992-11-11 | Excorim Ab | System foer behandling av en vaetska i en behandlingsanordning samt anvaendningen av detta system foer behandling av en biologisk vaetska |
| US5817042A (en) * | 1992-03-04 | 1998-10-06 | Cobe Laboratories, Inc. | Method and apparatus for controlling concentrations in vivos and in tubing systems |
| US5282981A (en) * | 1992-05-01 | 1994-02-01 | E. I. Du Pont De Nemours And Company | Flow restrictor-separation device |
| US5271852A (en) * | 1992-05-01 | 1993-12-21 | E. I. Du Pont De Nemours And Company | Centrifugal methods using a phase-separation tube |
| US5295953A (en) * | 1992-05-26 | 1994-03-22 | Hemagen/Pfc | Method and apparatus for extracorporeal separation of fluorochemicals from whole blood of a patient |
| DE4227695C1 (de) * | 1992-08-21 | 1993-10-07 | Fresenius Ag | Zentrifuge zum Auftrennen von Blut in seine Bestandteile |
| US5437598A (en) * | 1994-01-21 | 1995-08-01 | Cobe Laboratories, Inc. | Automation of plasma sequestration |
| US5478479A (en) * | 1994-05-20 | 1995-12-26 | Haemonetics Corporation | Two-stage cell wash process controlled by optical sensor |
| US7332125B2 (en) * | 1994-10-13 | 2008-02-19 | Haemonetics Corporation | System and method for processing blood |
| US5651766A (en) | 1995-06-07 | 1997-07-29 | Transfusion Technologies Corporation | Blood collection and separation system |
| US5733253A (en) * | 1994-10-13 | 1998-03-31 | Transfusion Technologies Corporation | Fluid separation system |
| US6632191B1 (en) | 1994-10-13 | 2003-10-14 | Haemonetics Corporation | System and method for separating blood components |
| US5704889A (en) * | 1995-04-14 | 1998-01-06 | Cobe Laboratories, Inc. | Spillover collection of sparse components such as mononuclear cells in a centrifuge apparatus |
| US5704888A (en) * | 1995-04-14 | 1998-01-06 | Cobe Laboratories, Inc. | Intermittent collection of mononuclear cells in a centrifuge apparatus |
| NZ336397A (en) * | 1997-01-08 | 2001-01-26 | Bristol Myers Squibb Co | Centrifuge apparatus comprising a piston displaceable in a cylindrical member and an optical blood cell detector |
| US6296602B1 (en) | 1999-03-17 | 2001-10-02 | Transfusion Technologies Corporation | Method for collecting platelets and other blood components from whole blood |
| US6284142B1 (en) * | 1999-09-03 | 2001-09-04 | Baxter International Inc. | Sensing systems and methods for differentiating between different cellular blood species during extracorporeal blood separation or processing |
| AU2003247350A1 (en) * | 2002-04-24 | 2003-11-10 | Interpore Orthopaedics, Inc. | Blood separation ande concentration system |
| US7327443B2 (en) * | 2004-07-01 | 2008-02-05 | Gambro Bct, Inc | Stroboscopic LED light source for blood processing apparatus |
| CN1809739A (zh) * | 2003-07-02 | 2006-07-26 | 甘布罗公司 | 用于血液处理的监测和控制系统 |
| US7671975B2 (en) * | 2004-07-01 | 2010-03-02 | Caridianbct, Inc. | Blood processing apparatus with dedicated stroboscopic controller for LED source |
| WO2007041716A1 (en) * | 2005-10-05 | 2007-04-12 | Gambro Bct, Inc. | Method and apparatus for leukoreduction of red blood cells |
| US7998052B2 (en) * | 2006-03-07 | 2011-08-16 | Jacques Chammas | Rotor defining a fluid separation chamber of varying volume |
| JP2010500900A (ja) | 2006-08-17 | 2010-01-14 | カリディアンビーシーティー、インコーポレーテッド | 頑強な自動プロセス制御を備える血液処理機器 |
| US20080041772A1 (en) * | 2006-08-17 | 2008-02-21 | Gambro Bct, Inc. | Blood Processing Apparatus with Robust Outflow Process Control |
| JP5209737B2 (ja) * | 2007-12-18 | 2013-06-12 | テルモ ビーシーティー、インコーポレーテッド | 光学制御装置の密封された散光器を有する血液処理装置 |
| US8066888B2 (en) * | 2007-12-27 | 2011-11-29 | Caridianbct, Inc. | Blood processing apparatus with controlled cell capture chamber trigger |
| US8702637B2 (en) * | 2008-04-14 | 2014-04-22 | Haemonetics Corporation | System and method for optimized apheresis draw and return |
| US8454548B2 (en) | 2008-04-14 | 2013-06-04 | Haemonetics Corporation | System and method for plasma reduced platelet collection |
| US8628489B2 (en) | 2008-04-14 | 2014-01-14 | Haemonetics Corporation | Three-line apheresis system and method |
| US7951059B2 (en) * | 2008-09-18 | 2011-05-31 | Caridianbct, Inc. | Blood processing apparatus with optical reference control |
| WO2010074929A2 (en) * | 2008-12-22 | 2010-07-01 | Caridianbct, Inc. | Blood processing apparatus with digitally controlled linear voltage regulator for optical pulses |
| US8834402B2 (en) * | 2009-03-12 | 2014-09-16 | Haemonetics Corporation | System and method for the re-anticoagulation of platelet rich plasma |
| US8535210B2 (en) * | 2009-12-11 | 2013-09-17 | Terumo Bct, Inc. | System for blood separation with shielded extraction port and optical control |
| CN103221078B (zh) | 2010-11-05 | 2015-09-16 | 赫摩耐提克斯公司 | 用于自动化血小板洗涤的系统和方法 |
| US9302042B2 (en) | 2010-12-30 | 2016-04-05 | Haemonetics Corporation | System and method for collecting platelets and anticipating plasma return |
| US11386993B2 (en) | 2011-05-18 | 2022-07-12 | Fenwal, Inc. | Plasma collection with remote programming |
| US9248446B2 (en) | 2013-02-18 | 2016-02-02 | Terumo Bct, Inc. | System for blood separation with a separation chamber having an internal gravity valve |
| WO2015148978A1 (en) | 2014-03-28 | 2015-10-01 | Terumo Bct, Inc. | Gain in separation processes with control loop |
| US9833557B2 (en) | 2014-12-19 | 2017-12-05 | Fenwal, Inc. | Systems and methods for determining free plasma hemoglobin |
| WO2017011527A1 (en) | 2015-07-13 | 2017-01-19 | Haemonetics Corporation | System and method for removing fat from salvaged blood |
| WO2017223318A1 (en) | 2016-06-24 | 2017-12-28 | Dominique Uhlmann | System and Method for Continuous Flow Red Blood Cell Washing |
| US10792416B2 (en) | 2017-05-30 | 2020-10-06 | Haemonetics Corporation | System and method for collecting plasma |
| US10758652B2 (en) | 2017-05-30 | 2020-09-01 | Haemonetics Corporation | System and method for collecting plasma |
| US12033750B2 (en) | 2018-05-21 | 2024-07-09 | Fenwal, Inc. | Plasma collection |
| US11412967B2 (en) | 2018-05-21 | 2022-08-16 | Fenwal, Inc. | Systems and methods for plasma collection |
| HUE056564T2 (hu) | 2018-05-21 | 2022-02-28 | Fenwal Inc | Rendszerek plazmagyûjtõ térfogatok optimalizálására |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2876769A (en) * | 1955-10-11 | 1959-03-10 | Cordova Jose Juan | Apparatus for oxygenating, centrifuging and changing the temperature of blood |
| US3655123A (en) * | 1966-08-08 | 1972-04-11 | Us Health Education & Welfare | Continuous flow blood separator |
| US3489145A (en) * | 1966-08-08 | 1970-01-13 | Surgeon General Of The Public | Method and apparatus for continuous separation of blood in vivo |
| US3519201A (en) * | 1968-05-07 | 1970-07-07 | Us Health Education & Welfare | Seal means for blood separator and the like |
| US3802432A (en) * | 1972-05-18 | 1974-04-09 | I Djerassi | Apparatus for filtration-leukopheresis for separation and concentration of human granulocytes |
| US3812482A (en) * | 1973-02-26 | 1974-05-21 | Primary Childrens Hospital | Air emboli detector |
| US3892236A (en) * | 1973-04-02 | 1975-07-01 | Isaac Djerassi | Apparatus for filtration-leukopheresis for separation and concentration of human granulocytes |
| US4086924A (en) * | 1976-10-06 | 1978-05-02 | Haemonetics Corporation | Plasmapheresis apparatus |
-
1977
- 1977-11-11 US US05/850,624 patent/US4151844A/en not_active Expired - Lifetime
-
1978
- 1978-10-25 CA CA314,241A patent/CA1088035A/en not_active Expired
- 1978-11-09 DE DE19782848683 patent/DE2848683A1/de not_active Withdrawn
- 1978-11-09 JP JP13836678A patent/JPS5476814A/ja active Granted
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0028842A3 (en) * | 1978-12-13 | 1981-10-28 | Antonio Ferrante | Improved medium for the separation of human blood leucocytes |
| DE3147377A1 (de) * | 1981-11-30 | 1983-06-01 | Akzo Gmbh, 5600 Wuppertal | Verfahren und vorrichtung zur extrakorporalen entfernung von an eiweisskoerpern gebundenen toxinen |
| DE4129516A1 (de) * | 1991-09-06 | 1993-03-18 | Fresenius Ag | Verfahren und vorrichtung zum trennen von blut in seine bestandteile |
| DE4129516C2 (de) * | 1991-09-06 | 2000-03-09 | Fresenius Ag | Verfahren und Vorrichtung zum Trennen von Blut in seine Bestandteile |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6320553B2 (enExample) | 1988-04-28 |
| CA1088035A (en) | 1980-10-21 |
| JPS5476814A (en) | 1979-06-19 |
| US4151844A (en) | 1979-05-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8128 | New person/name/address of the agent |
Representative=s name: KERN, R., DIPL.-ING., PAT.-ANW., 8000 MUENCHEN |
|
| 8128 | New person/name/address of the agent |
Representative=s name: POPP, E., DIPL.-ING.DIPL.-WIRTSCH.-ING.DR.RER.POL. |
|
| 8128 | New person/name/address of the agent |
Representative=s name: POPP, E., DIPL.-ING.DIPL.-WIRTSCH.-ING.DR.RER.POL. |
|
| 8141 | Disposal/no request for examination |