CA1088035A - Method and apparatus for separating whole blood into components thereof and for automatically collecting one of the components - Google Patents

Method and apparatus for separating whole blood into components thereof and for automatically collecting one of the components

Info

Publication number
CA1088035A
CA1088035A CA314,241A CA314241A CA1088035A CA 1088035 A CA1088035 A CA 1088035A CA 314241 A CA314241 A CA 314241A CA 1088035 A CA1088035 A CA 1088035A
Authority
CA
Canada
Prior art keywords
speed
motor
withdrawal
gear
pump
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA314,241A
Other languages
English (en)
French (fr)
Inventor
Herbert M. Cullis
Anthony L. Almond
Rodolfo R. Rodriguez
Mirza A. Khoja
Michael B. Uffer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Baxter International Inc
Original Assignee
Baxter Travenol Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baxter Travenol Laboratories Inc filed Critical Baxter Travenol Laboratories Inc
Application granted granted Critical
Publication of CA1088035A publication Critical patent/CA1088035A/en
Expired legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B5/00—Other centrifuges
    • B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
    • B04B5/0442—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3693—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3693—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
    • A61M1/3696—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/04—Liquids
    • A61M2202/0413—Blood
    • A61M2202/0439—White blood cells; Leucocytes

Landscapes

  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • External Artificial Organs (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CA314,241A 1977-11-11 1978-10-25 Method and apparatus for separating whole blood into components thereof and for automatically collecting one of the components Expired CA1088035A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US850,624 1977-11-11
US05/850,624 US4151844A (en) 1977-11-11 1977-11-11 Method and apparatus for separating whole blood into its components and for automatically collecting one component

Publications (1)

Publication Number Publication Date
CA1088035A true CA1088035A (en) 1980-10-21

Family

ID=25308676

Family Applications (1)

Application Number Title Priority Date Filing Date
CA314,241A Expired CA1088035A (en) 1977-11-11 1978-10-25 Method and apparatus for separating whole blood into components thereof and for automatically collecting one of the components

Country Status (4)

Country Link
US (1) US4151844A (enExample)
JP (1) JPS5476814A (enExample)
CA (1) CA1088035A (enExample)
DE (1) DE2848683A1 (enExample)

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AU524397B2 (en) * 1978-12-13 1982-09-16 Antonio Ferrante Medium for separation of human blood leukocytes
US4216770A (en) * 1979-02-09 1980-08-12 Baxter Travenol Laboratories, Inc. Sickle cell therapeutic treatment
JPS5666756A (en) * 1979-11-02 1981-06-05 Asahi Chem Ind Co Ltd Control method of centrifugal processing and its device
JPS5749461A (en) * 1980-09-10 1982-03-23 Asahi Chemical Ind Blood treating vessel, device and method for separating platelet
JPS5749460A (en) * 1980-09-09 1982-03-23 Asahi Chemical Ind Blood treating vessel, device and method for separating polyplatelet blood plasma
US4389206A (en) * 1980-10-09 1983-06-21 Baxter Travenol Laboratories, Inc. Centrifugal processing apparatus and rotatable processing bowl apparatus
US4389207A (en) * 1981-03-16 1983-06-21 Baxter Travenol Laboratories, Inc. Rotatable bowl assembly for centrifugal processing apparatus having a bonded and prewound umbilical system
US4623470A (en) * 1981-11-09 1986-11-18 Helipump, Inc. Process and apparatus for separating or fractionating fluid mixtures
US4531932A (en) * 1981-11-27 1985-07-30 Dideco S.P.A. Centrifugal plasmapheresis device
DE3147377A1 (de) * 1981-11-30 1983-06-01 Akzo Gmbh, 5600 Wuppertal Verfahren und vorrichtung zur extrakorporalen entfernung von an eiweisskoerpern gebundenen toxinen
WO1983002059A1 (en) * 1981-12-15 1983-06-23 Baxter Travenol Lab Blood fractionation apparatus
US4582598A (en) * 1981-12-15 1986-04-15 Baxter Travenol Laboratories, Inc. Replacement fluid control system for a blood fractionation apparatus and the like
US4458539A (en) * 1981-12-15 1984-07-10 Baxter Travenol Laboratories, Inc. Blood fractionation apparatus having collected volume display system
US4481827A (en) * 1981-12-15 1984-11-13 Baxter Travenol Laboratories, Inc. Blood fractionation apparatus having collection rate display system
ZA839064B (en) * 1982-12-06 1985-07-31 Broken Hill Pty Co Ltd Centrifugal separation method and apparatus
JPS6031763A (ja) * 1983-07-29 1985-02-18 オムロン株式会社 血液成分の自動採取装置
WO1985002561A1 (en) * 1983-12-13 1985-06-20 Baxter Travenol Laboratories, Inc. Flexible disposable centrifuge system
US4530691A (en) * 1983-12-13 1985-07-23 Baxter Travenol Laboratories, Inc. Centrifuge with movable mandrel
JPS60153869A (ja) * 1984-01-23 1985-08-13 日立工機株式会社 成分採血装置用境界検知器
DE3410286C2 (de) * 1984-03-21 1986-01-23 Fresenius AG, 6380 Bad Homburg Verfahren zur Trennung von Blut sowie Vorrichtung zur Durchführung des Verfahrens
US4692136A (en) * 1985-10-11 1987-09-08 Cardiovascular Systems Inc. Centrifuge
US4795419A (en) * 1985-10-11 1989-01-03 Kardiothor, Inc. Centrifuge
US4718888A (en) * 1986-03-10 1988-01-12 Cardiovascular Systems, Inc. Centrifuge bowl mount
DE3632176A1 (de) * 1986-09-22 1988-04-07 Fresenius Ag Steuerung eines systems zur trennung der bestandteile des einem spender "in vivo" entnommenen blutes
US4808151A (en) * 1987-04-27 1989-02-28 E. I. Du Pont De Nemours And Company Simplified method for the preparation of human lymphokine activated killer cells
US4807845A (en) * 1987-09-30 1989-02-28 Kardiothor, Inc. Tube valve
DE3931471A1 (de) * 1989-09-21 1991-04-11 Fresenius Ag Verfahren und vorrichtung zur trennung von blut mittels einer zentrifuge
US5112298A (en) * 1990-06-25 1992-05-12 Baxter International Inc. Apheresis method and device
SE9101413L (sv) * 1991-05-10 1992-11-11 Excorim Ab System foer behandling av en vaetska i en behandlingsanordning samt anvaendningen av detta system foer behandling av en biologisk vaetska
DE4129516C2 (de) * 1991-09-06 2000-03-09 Fresenius Ag Verfahren und Vorrichtung zum Trennen von Blut in seine Bestandteile
US5817042A (en) * 1992-03-04 1998-10-06 Cobe Laboratories, Inc. Method and apparatus for controlling concentrations in vivos and in tubing systems
US5271852A (en) * 1992-05-01 1993-12-21 E. I. Du Pont De Nemours And Company Centrifugal methods using a phase-separation tube
US5282981A (en) * 1992-05-01 1994-02-01 E. I. Du Pont De Nemours And Company Flow restrictor-separation device
US5295953A (en) * 1992-05-26 1994-03-22 Hemagen/Pfc Method and apparatus for extracorporeal separation of fluorochemicals from whole blood of a patient
DE4227695C1 (de) * 1992-08-21 1993-10-07 Fresenius Ag Zentrifuge zum Auftrennen von Blut in seine Bestandteile
US5437598A (en) * 1994-01-21 1995-08-01 Cobe Laboratories, Inc. Automation of plasma sequestration
US5478479A (en) * 1994-05-20 1995-12-26 Haemonetics Corporation Two-stage cell wash process controlled by optical sensor
US7332125B2 (en) * 1994-10-13 2008-02-19 Haemonetics Corporation System and method for processing blood
US5651766A (en) * 1995-06-07 1997-07-29 Transfusion Technologies Corporation Blood collection and separation system
US5733253A (en) * 1994-10-13 1998-03-31 Transfusion Technologies Corporation Fluid separation system
US6632191B1 (en) 1994-10-13 2003-10-14 Haemonetics Corporation System and method for separating blood components
US5704889A (en) * 1995-04-14 1998-01-06 Cobe Laboratories, Inc. Spillover collection of sparse components such as mononuclear cells in a centrifuge apparatus
US5704888A (en) * 1995-04-14 1998-01-06 Cobe Laboratories, Inc. Intermittent collection of mononuclear cells in a centrifuge apparatus
EP0951360A4 (en) * 1997-01-08 2003-08-27 Bristol Myers Squibb Co BLOOD SEPARATION CENTRIFUGE
US6296602B1 (en) 1999-03-17 2001-10-02 Transfusion Technologies Corporation Method for collecting platelets and other blood components from whole blood
US6284142B1 (en) * 1999-09-03 2001-09-04 Baxter International Inc. Sensing systems and methods for differentiating between different cellular blood species during extracorporeal blood separation or processing
WO2003090839A1 (en) 2002-04-24 2003-11-06 Interpore Orthopaedics Blood separation and concentration system
CA2799684C (en) * 2003-07-02 2013-12-24 Terumo Bct, Inc. Monitoring and control system for blood processing
US7327443B2 (en) * 2004-07-01 2008-02-05 Gambro Bct, Inc Stroboscopic LED light source for blood processing apparatus
US7671975B2 (en) * 2004-07-01 2010-03-02 Caridianbct, Inc. Blood processing apparatus with dedicated stroboscopic controller for LED source
US20070118063A1 (en) * 2005-10-05 2007-05-24 Gambro, Inc Method and Apparatus for Leukoreduction of Red Blood Cells
US7998052B2 (en) * 2006-03-07 2011-08-16 Jacques Chammas Rotor defining a fluid separation chamber of varying volume
US8337379B2 (en) * 2006-08-17 2012-12-25 Terumo Bct, Inc. Blood processing apparatus with robust automated process control
US20080041772A1 (en) * 2006-08-17 2008-02-21 Gambro Bct, Inc. Blood Processing Apparatus with Robust Outflow Process Control
US8057376B2 (en) * 2007-12-18 2011-11-15 Caridianbct, Inc. Blood processing apparatus with sealed diffuser in optical control apparatus
WO2009085350A1 (en) * 2007-12-27 2009-07-09 Caridianbct, Inc. Blood processing apparatus with controlled cell capture chamber trigger
US8628489B2 (en) * 2008-04-14 2014-01-14 Haemonetics Corporation Three-line apheresis system and method
US8454548B2 (en) * 2008-04-14 2013-06-04 Haemonetics Corporation System and method for plasma reduced platelet collection
US8702637B2 (en) * 2008-04-14 2014-04-22 Haemonetics Corporation System and method for optimized apheresis draw and return
US7951059B2 (en) * 2008-09-18 2011-05-31 Caridianbct, Inc. Blood processing apparatus with optical reference control
US8241196B2 (en) * 2008-12-22 2012-08-14 Terumo Bct, Inc. Blood processing apparatus with digitally controlled linear voltage regulator for optical pulses
US8834402B2 (en) * 2009-03-12 2014-09-16 Haemonetics Corporation System and method for the re-anticoagulation of platelet rich plasma
JP5631410B2 (ja) 2009-12-11 2014-11-26 テルモ ビーシーティー、インコーポレーテッド シールド付きの抽出ポート及び光学的制御を有する血液分離システム
CN103221078B (zh) 2010-11-05 2015-09-16 赫摩耐提克斯公司 用于自动化血小板洗涤的系统和方法
US9302042B2 (en) 2010-12-30 2016-04-05 Haemonetics Corporation System and method for collecting platelets and anticipating plasma return
US11386993B2 (en) 2011-05-18 2022-07-12 Fenwal, Inc. Plasma collection with remote programming
WO2014127122A1 (en) 2013-02-18 2014-08-21 Terumo Bct, Inc. System for blood separation with a separation chamber having an internal gravity valve
US10166322B2 (en) 2014-03-28 2019-01-01 Terumo Bct, Inc. Gain in separation processes with control loop
US9833557B2 (en) 2014-12-19 2017-12-05 Fenwal, Inc. Systems and methods for determining free plasma hemoglobin
JP6912391B2 (ja) 2015-07-13 2021-08-04 ヘモネティクス・コーポレーションＨａｅｍｏｎｅｔｉｃｓ Ｃｏｒｐｏｒａｔｉｏｎ 回収血液から脂肪を除去するためのシステム及び方法
US11541161B2 (en) 2016-06-24 2023-01-03 Haemonetics Corporation System and method for continuous flow red blood cell washing
US10792416B2 (en) 2017-05-30 2020-10-06 Haemonetics Corporation System and method for collecting plasma
US10758652B2 (en) 2017-05-30 2020-09-01 Haemonetics Corporation System and method for collecting plasma
HUE056564T2 (hu) 2018-05-21 2022-02-28 Fenwal Inc Rendszerek plazmagyûjtõ térfogatok optimalizálására
US12033750B2 (en) 2018-05-21 2024-07-09 Fenwal, Inc. Plasma collection
US11412967B2 (en) 2018-05-21 2022-08-16 Fenwal, Inc. Systems and methods for plasma collection

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US3655123A (en) * 1966-08-08 1972-04-11 Us Health Education & Welfare Continuous flow blood separator
US3489145A (en) * 1966-08-08 1970-01-13 Surgeon General Of The Public Method and apparatus for continuous separation of blood in vivo
US3519201A (en) * 1968-05-07 1970-07-07 Us Health Education & Welfare Seal means for blood separator and the like
US3802432A (en) * 1972-05-18 1974-04-09 I Djerassi Apparatus for filtration-leukopheresis for separation and concentration of human granulocytes
US3812482A (en) * 1973-02-26 1974-05-21 Primary Childrens Hospital Air emboli detector
US3892236A (en) * 1973-04-02 1975-07-01 Isaac Djerassi Apparatus for filtration-leukopheresis for separation and concentration of human granulocytes
US4086924A (en) * 1976-10-06 1978-05-02 Haemonetics Corporation Plasmapheresis apparatus

Also Published As

Publication number Publication date
US4151844A (en) 1979-05-01
JPS6320553B2 (enExample) 1988-04-28
JPS5476814A (en) 1979-06-19
DE2848683A1 (de) 1979-05-17

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Legal Events

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