DE2831671A1 - Neue substituierte 2-phenylamino-imidazoline-(2), deren saeureadditionssalze, diese enthaltende arzneimittel und verfahren zur herstellung derselben - Google Patents

Neue substituierte 2-phenylamino-imidazoline-(2), deren saeureadditionssalze, diese enthaltende arzneimittel und verfahren zur herstellung derselben

Info

Publication number
DE2831671A1
DE2831671A1 DE19782831671 DE2831671A DE2831671A1 DE 2831671 A1 DE2831671 A1 DE 2831671A1 DE 19782831671 DE19782831671 DE 19782831671 DE 2831671 A DE2831671 A DE 2831671A DE 2831671 A1 DE2831671 A1 DE 2831671A1
Authority
DE
Germany
Prior art keywords
general formula
acid addition
addition salts
imidazoline
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19782831671
Other languages
German (de)
English (en)
Inventor
Walter Prof Dr Kobinger
Herbert Dr Koeppe
Werner Dr Kummer
Christian Dr Lillie
Ludwig Dr Pichler
Helmut Dr Staehle
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
C.H. Boehringer Sohn AG and Co KG
Original Assignee
C.H. Boehringer Sohn AG and Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by C.H. Boehringer Sohn AG and Co KG filed Critical C.H. Boehringer Sohn AG and Co KG
Priority to DE19782831671 priority Critical patent/DE2831671A1/de
Priority to EP79102052A priority patent/EP0007438B1/de
Priority to DE7979102052T priority patent/DE2963605D1/de
Priority to AT79102052T priority patent/ATE1503T1/de
Priority to JP8600679A priority patent/JPS5515466A/ja
Priority to GR59597A priority patent/GR69931B/el
Priority to US06/058,165 priority patent/US4277487A/en
Priority to FI792251A priority patent/FI69067C/fi
Priority to NZ191052A priority patent/NZ191052A/xx
Priority to AU49022/79A priority patent/AU524192B2/en
Priority to CA000332040A priority patent/CA1121824A/en
Priority to ZA00793636A priority patent/ZA793636B/xx
Priority to ES482581A priority patent/ES482581A1/es
Priority to DK302679A priority patent/DK146939C/da
Priority to IL57834A priority patent/IL57834A/xx
Priority to NO792389A priority patent/NO150435C/no
Priority to PT69934A priority patent/PT69934A/pt
Priority to IE1356/79A priority patent/IE48452B1/en
Publication of DE2831671A1 publication Critical patent/DE2831671A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/44—Nitrogen atoms not forming part of a nitro radical
    • C07D233/50—Nitrogen atoms not forming part of a nitro radical with carbocyclic radicals directly attached to said nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE19782831671 1978-07-19 1978-07-19 Neue substituierte 2-phenylamino-imidazoline-(2), deren saeureadditionssalze, diese enthaltende arzneimittel und verfahren zur herstellung derselben Withdrawn DE2831671A1 (de)

Priority Applications (18)

Application Number Priority Date Filing Date Title
DE19782831671 DE2831671A1 (de) 1978-07-19 1978-07-19 Neue substituierte 2-phenylamino-imidazoline-(2), deren saeureadditionssalze, diese enthaltende arzneimittel und verfahren zur herstellung derselben
EP79102052A EP0007438B1 (de) 1978-07-19 1979-06-21 Neue substituierte 2-Phenylamino-imidazoline-(2), deren Säureadditionssalze, diese enthaltende Arzneimittel und Verfahren zur Herstellung derselben
DE7979102052T DE2963605D1 (en) 1978-07-19 1979-06-21 Substituted 2-phenylamino-2-imidazolines, their acid addition salts, pharmaceutical compositions containing them and process for their preparation
AT79102052T ATE1503T1 (de) 1978-07-19 1979-06-21 Neue substituierte 2-phenylamino-imidazoline-(2), deren saeureadditionssalze, diese enthaltende arzneimittel und verfahren zur herstellung derselben.
JP8600679A JPS5515466A (en) 1978-07-19 1979-07-09 Imidazole derivative and medical composition
GR59597A GR69931B (enExample) 1978-07-19 1979-07-13
US06/058,165 US4277487A (en) 1978-07-19 1979-07-17 Substituted 2-phenylamino-2-imidazolines as bradycardiacs
FI792251A FI69067C (fi) 1978-07-19 1979-07-18 Foerfarande foer framstaellning av terapeutiskt verkande substituerade 2-fenylamino-imidazoliner-(2)
NZ191052A NZ191052A (en) 1978-07-19 1979-07-18 Substituted 2-phenylamino-2-imidazolines; pharmaceutical compositions
AU49022/79A AU524192B2 (en) 1978-07-19 1979-07-18 Substituted 2-phenylamino-2-imidazolines
CA000332040A CA1121824A (en) 1978-07-19 1979-07-18 Substituted 2-phenylamino-imidazolines-(2), their acid addition salts, pharmaceuticals comprising same and processes for their production
ZA00793636A ZA793636B (en) 1978-07-19 1979-07-18 Substituted 2-phenylamino-2-imidazolines,acid addition salts thereof,processes for their preparation,and pharmaceutical composition,and pharmaceutical compositions containing these compounds
ES482581A ES482581A1 (es) 1978-07-19 1979-07-18 Procedimiento para la preparacion de 2-fenilamino-imidazoli-nas-(2) sustituidas.
DK302679A DK146939C (da) 1978-07-19 1979-07-18 Analogifremgangsmaade til fremstilling af substituerede 2-phenylamino-imidazolin-(2)-er eller syreadditionssalte deraf
IL57834A IL57834A (en) 1978-07-19 1979-07-18 Substituted 2-phenylamino-2-imidazolines and salts thereof,their preparation and pharmaceutical compositions containing them
NO792389A NO150435C (no) 1978-07-19 1979-07-18 Analogifremgangsmaate for fremstilling av terapeutisk aktive fenylamino-imidazolin-derivater
PT69934A PT69934A (de) 1978-07-19 1979-07-18 Neue substituierte 2-phenylamino-imidazoline-(2) deren saureadditionssalze diese enthaltende arzneimittel und verfahren zur herstellung derselben
IE1356/79A IE48452B1 (en) 1978-07-19 1979-08-08 Novel substituted 2-phenylamino-imidazolines-(2),acid addition salts thereof,pharmaceutical compositions containing same and process for their production

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19782831671 DE2831671A1 (de) 1978-07-19 1978-07-19 Neue substituierte 2-phenylamino-imidazoline-(2), deren saeureadditionssalze, diese enthaltende arzneimittel und verfahren zur herstellung derselben

Publications (1)

Publication Number Publication Date
DE2831671A1 true DE2831671A1 (de) 1980-02-07

Family

ID=6044762

Family Applications (2)

Application Number Title Priority Date Filing Date
DE19782831671 Withdrawn DE2831671A1 (de) 1978-07-19 1978-07-19 Neue substituierte 2-phenylamino-imidazoline-(2), deren saeureadditionssalze, diese enthaltende arzneimittel und verfahren zur herstellung derselben
DE7979102052T Expired DE2963605D1 (en) 1978-07-19 1979-06-21 Substituted 2-phenylamino-2-imidazolines, their acid addition salts, pharmaceutical compositions containing them and process for their preparation

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE7979102052T Expired DE2963605D1 (en) 1978-07-19 1979-06-21 Substituted 2-phenylamino-2-imidazolines, their acid addition salts, pharmaceutical compositions containing them and process for their preparation

Country Status (17)

Country Link
US (1) US4277487A (enExample)
EP (1) EP0007438B1 (enExample)
JP (1) JPS5515466A (enExample)
AT (1) ATE1503T1 (enExample)
AU (1) AU524192B2 (enExample)
CA (1) CA1121824A (enExample)
DE (2) DE2831671A1 (enExample)
DK (1) DK146939C (enExample)
ES (1) ES482581A1 (enExample)
FI (1) FI69067C (enExample)
GR (1) GR69931B (enExample)
IE (1) IE48452B1 (enExample)
IL (1) IL57834A (enExample)
NO (1) NO150435C (enExample)
NZ (1) NZ191052A (enExample)
PT (1) PT69934A (enExample)
ZA (1) ZA793636B (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2947563A1 (de) * 1979-11-26 1981-06-04 C.H. Boehringer Sohn, 6507 Ingelheim Neue substituierte 2-phenylamino-imidazoline-(2), deren saeureadditionssalze, diese enthaltende arzneimittel und verfahren zur herstellung derselben
DE2950345A1 (de) * 1979-12-14 1981-07-02 C.H. Boehringer Sohn, 6507 Ingelheim Neue substituierte 2-phenylaminoimidazoline-(2), deren saeureadditionssalze, diese enthaltende arzneimittel und verfahren zur herstellung derselben
FR2499991A1 (fr) * 1981-02-19 1982-08-20 Sandoz Sa Nouveaux 2,1,3-benzothiadiazoles et 2,1,3-benzoxadiazoles, leur preparation et leur application comme medicaments
US4393077A (en) * 1981-07-02 1983-07-12 William H. Rorer, Inc. 1-Methylene-1-phenylguanidine compounds
IT1211138B (it) * 1981-12-01 1989-09-29 Ausonia Farma Srl Composto antiipertensivo procedimento per la sua preparazione e relative composizioni farmaceutiche.
DE3514351A1 (de) * 1985-04-20 1986-11-06 Boehringer Ingelheim KG, 6507 Ingelheim Neue substituierte 2-(n-alkinyl-n-phenyl)amino)-imidazolinderivate, deren saeureadditionssalze, diese enthaltende arzneimittel und verfahren zu deren herstellung

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE759125A (fr) * 1969-11-19 1971-05-18 Boehringer Sohn Ingelheim Nouvelles n-allyl-2-arylamino-imidazolines-(2) substituees et procedes pour les fabriquer
DE2102733A1 (en) * 1971-01-21 1972-08-03 CH. Boehringer Sohn, 6507 Ingelheim 2-arylamino-2-imidazolines
DD95843A5 (enExample) * 1971-01-21 1973-02-20
US3850926A (en) * 1971-01-21 1974-11-26 Boehringer Sohn Ingelheim 2-(n-substituted-phenylamino)-imidazolines-(2)

Also Published As

Publication number Publication date
IL57834A0 (en) 1979-11-30
ES482581A1 (es) 1980-04-01
AU524192B2 (en) 1982-09-02
GR69931B (enExample) 1982-07-21
FI792251A7 (fi) 1980-01-20
IE791356L (en) 1980-01-19
EP0007438A1 (de) 1980-02-06
NO150435B (no) 1984-07-09
ATE1503T1 (de) 1982-09-15
NZ191052A (en) 1981-02-11
IE48452B1 (en) 1985-01-23
NO150435C (no) 1984-10-17
JPS5515466A (en) 1980-02-02
DK146939B (da) 1984-02-20
DK146939C (da) 1984-07-30
US4277487A (en) 1981-07-07
FI69067C (fi) 1985-12-10
AU4902279A (en) 1980-01-24
CA1121824A (en) 1982-04-13
NO792389L (no) 1980-01-22
ZA793636B (en) 1981-03-25
EP0007438B1 (de) 1982-09-01
DE2963605D1 (en) 1982-10-28
PT69934A (de) 1979-08-01
IL57834A (en) 1983-03-31
DK302679A (da) 1980-01-20
FI69067B (fi) 1985-08-30

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Legal Events

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8139 Disposal/non-payment of the annual fee