DE2803920A1 - Verfahren zur gewinnung von hepatitis b-oberflaechenantigen - Google Patents

Verfahren zur gewinnung von hepatitis b-oberflaechenantigen

Info

Publication number
DE2803920A1
DE2803920A1 DE19782803920 DE2803920A DE2803920A1 DE 2803920 A1 DE2803920 A1 DE 2803920A1 DE 19782803920 DE19782803920 DE 19782803920 DE 2803920 A DE2803920 A DE 2803920A DE 2803920 A1 DE2803920 A1 DE 2803920A1
Authority
DE
Germany
Prior art keywords
banding
ammonium sulfate
plasma
liquid
isopycnic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
DE19782803920
Other languages
German (de)
English (en)
Other versions
DE2803920C2 (enExample
Inventor
William Joseph Mcaleer
Edward Henry Wasmuth
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Priority to DE19782803920 priority Critical patent/DE2803920A1/de
Publication of DE2803920A1 publication Critical patent/DE2803920A1/de
Application granted granted Critical
Publication of DE2803920C2 publication Critical patent/DE2803920C2/de
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00—Reverse transcribing DNA viruses
    • C12N2730/00011—Details
    • C12N2730/10011—Hepadnaviridae
    • C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Centrifugal Separators (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DE19782803920 1978-01-30 1978-01-30 Verfahren zur gewinnung von hepatitis b-oberflaechenantigen Granted DE2803920A1 (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DE19782803920 DE2803920A1 (de) 1978-01-30 1978-01-30 Verfahren zur gewinnung von hepatitis b-oberflaechenantigen

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19782803920 DE2803920A1 (de) 1978-01-30 1978-01-30 Verfahren zur gewinnung von hepatitis b-oberflaechenantigen

Publications (2)

Publication Number Publication Date
DE2803920A1 true DE2803920A1 (de) 1979-08-02
DE2803920C2 DE2803920C2 (enExample) 1987-12-03

Family

ID=6030720

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19782803920 Granted DE2803920A1 (de) 1978-01-30 1978-01-30 Verfahren zur gewinnung von hepatitis b-oberflaechenantigen

Country Status (1)

Country Link
DE (1) DE2803920A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2470795A1 (fr) * 1979-12-07 1981-06-12 Pasteur Institut Procede de purification de particules d'origine biologique, notamment de l'antigene de surface du virus de l'hepatite b (aghbs) et les produits obtenus

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3951937A (en) * 1973-12-20 1976-04-20 The Community Blood Council Of Greater New York, Inc. Large scale purification of hepatitis type B antigen using polyethylene glycol
US4024243A (en) * 1975-06-16 1977-05-17 Merck & Co., Inc. Process for isolating hepatitis B antigen

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3951937A (en) * 1973-12-20 1976-04-20 The Community Blood Council Of Greater New York, Inc. Large scale purification of hepatitis type B antigen using polyethylene glycol
US4024243A (en) * 1975-06-16 1977-05-17 Merck & Co., Inc. Process for isolating hepatitis B antigen

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Der Internist 14, 546-553, 1973 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2470795A1 (fr) * 1979-12-07 1981-06-12 Pasteur Institut Procede de purification de particules d'origine biologique, notamment de l'antigene de surface du virus de l'hepatite b (aghbs) et les produits obtenus

Also Published As

Publication number Publication date
DE2803920C2 (enExample) 1987-12-03

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Legal Events

Date Code Title Description
8110 Request for examination paragraph 44
D2 Grant after examination
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee