DE2727670A1 - Neue dipeptide, verfahren zur ihrer herstellung und pharmazeutische praeparate enthaltende solche dipeptide - Google Patents

Neue dipeptide, verfahren zur ihrer herstellung und pharmazeutische praeparate enthaltende solche dipeptide

Info

Publication number
DE2727670A1
DE2727670A1 DE19772727670 DE2727670A DE2727670A1 DE 2727670 A1 DE2727670 A1 DE 2727670A1 DE 19772727670 DE19772727670 DE 19772727670 DE 2727670 A DE2727670 A DE 2727670A DE 2727670 A1 DE2727670 A1 DE 2727670A1
Authority
DE
Germany
Prior art keywords
phenyl
ethylamide
alanyl
alkanoyl
proline
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19772727670
Other languages
German (de)
English (en)
Inventor
Cedric Herbert Hassall
William Henry Johnson
Noel Allan Roberts
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB25645/76A external-priority patent/GB1581543A/en
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of DE2727670A1 publication Critical patent/DE2727670A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Rheumatology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE19772727670 1976-06-21 1977-06-20 Neue dipeptide, verfahren zur ihrer herstellung und pharmazeutische praeparate enthaltende solche dipeptide Withdrawn DE2727670A1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB25645/76A GB1581543A (en) 1976-06-21 1976-06-21 Dipeptide derivatives
GB3249676 1976-08-04
GB1199777 1977-03-22

Publications (1)

Publication Number Publication Date
DE2727670A1 true DE2727670A1 (de) 1977-12-29

Family

ID=27256763

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19772727670 Withdrawn DE2727670A1 (de) 1976-06-21 1977-06-20 Neue dipeptide, verfahren zur ihrer herstellung und pharmazeutische praeparate enthaltende solche dipeptide

Country Status (17)

Country Link
US (1) US4176116A (enExample)
JP (1) JPS52156811A (enExample)
AT (1) AT355741B (enExample)
AU (1) AU510077B2 (enExample)
CA (1) CA1095027A (enExample)
CH (1) CH626872A5 (enExample)
DE (1) DE2727670A1 (enExample)
DK (1) DK271977A (enExample)
FR (1) FR2361346A1 (enExample)
IE (1) IE45095B1 (enExample)
IL (1) IL52307A (enExample)
IT (1) IT1203108B (enExample)
LU (1) LU77580A1 (enExample)
NL (1) NL7706827A (enExample)
NZ (1) NZ184394A (enExample)
PH (1) PH14589A (enExample)
SE (1) SE7707129L (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0003056A1 (de) * 1977-12-30 1979-07-25 Byk Gulden Lomberg Chemische Fabrik GmbH N-substituierte omega-Aminoalkanoyl-omega-aminoalkansäuren, ihre Verwendung und Verfahren zu ihrer Herstellung sowie diese Verbindungen enthaltende Arzneimittel
WO1996035805A3 (fr) * 1995-05-09 1997-01-30 Inst Nat Sante Rech Med Inhibiteurs de tripeptidylpeptidases

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4277395A (en) * 1980-06-16 1981-07-07 Richardson-Merrell Inc. Novel enzyme inhibitors
US4309342A (en) * 1980-07-03 1982-01-05 Abbott Laboratories Antibacterial peptides
US4462943A (en) * 1980-11-24 1984-07-31 E. R. Squibb & Sons, Inc. Carboxyalkyl amino acid derivatives of various substituted prolines
US4820729A (en) * 1981-03-30 1989-04-11 Rorer Pharmaceutical Corporation N-substituted-amido-amino acids
CS226907B1 (en) * 1981-08-07 1984-04-16 Kasafirek Evzen Alkylamides of carboxyalkanoylpeptides
EP0132441A1 (en) * 1983-01-26 1985-02-06 University Patents, Inc. Antibacterial peptides
JPH0513980U (ja) * 1991-07-29 1993-02-23 アラコ株式会社 ツールバツグ
JPH05345754A (ja) * 1992-06-15 1993-12-27 Suntory Ltd ジペプチド誘導体およびそれを有効成分とする骨疾患の予防または治療剤
US8754107B2 (en) * 2006-11-17 2014-06-17 Abbvie Inc. Aminopyrrolidines as chemokine receptor antagonists
US20260062443A1 (en) * 2022-08-23 2026-03-05 Alexion Pharmaceuticals, Inc. Pharmaceutical compounds for the treatment of complement mediated disorders

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5255593A (en) * 1975-10-30 1977-05-07 Ajinomoto Kk Measuring method of enzyme activity

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0003056A1 (de) * 1977-12-30 1979-07-25 Byk Gulden Lomberg Chemische Fabrik GmbH N-substituierte omega-Aminoalkanoyl-omega-aminoalkansäuren, ihre Verwendung und Verfahren zu ihrer Herstellung sowie diese Verbindungen enthaltende Arzneimittel
WO1996035805A3 (fr) * 1995-05-09 1997-01-30 Inst Nat Sante Rech Med Inhibiteurs de tripeptidylpeptidases

Also Published As

Publication number Publication date
FR2361346B1 (enExample) 1980-04-04
PH14589A (en) 1981-09-29
IE45095B1 (en) 1982-06-16
ATA432877A (de) 1979-08-15
NL7706827A (nl) 1977-12-23
IT1203108B (it) 1989-02-15
US4176116A (en) 1979-11-27
AU510077B2 (en) 1980-06-05
AT355741B (de) 1980-03-25
IE45095L (en) 1977-12-21
IL52307A0 (en) 1977-08-31
SE7707129L (sv) 1977-12-22
CA1095027A (en) 1981-02-03
CH626872A5 (enExample) 1981-12-15
NZ184394A (en) 1980-08-26
JPS52156811A (en) 1977-12-27
FR2361346A1 (fr) 1978-03-10
AU2610777A (en) 1978-12-21
IL52307A (en) 1980-11-30
DK271977A (da) 1977-12-22
LU77580A1 (enExample) 1978-07-11

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Legal Events

Date Code Title Description
OB Request for examination as to novelty
OC Search report available
8139 Disposal/non-payment of the annual fee