DE2705883A1 - Neue anti-hypertonische zubereitungen - Google Patents

Neue anti-hypertonische zubereitungen

Info

Publication number
DE2705883A1
DE2705883A1 DE19772705883 DE2705883A DE2705883A1 DE 2705883 A1 DE2705883 A1 DE 2705883A1 DE 19772705883 DE19772705883 DE 19772705883 DE 2705883 A DE2705883 A DE 2705883A DE 2705883 A1 DE2705883 A1 DE 2705883A1
Authority
DE
Germany
Prior art keywords
methyl
benzimidazol
formula
amino
propionic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19772705883
Other languages
German (de)
English (en)
Inventor
Clement Addison Stone
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of DE2705883A1 publication Critical patent/DE2705883A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
    • C07D263/58—Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/26—Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE19772705883 1976-02-13 1977-02-11 Neue anti-hypertonische zubereitungen Withdrawn DE2705883A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/657,824 US4051251A (en) 1976-02-13 1976-02-13 Novel anti-hypertensive compositions

Publications (1)

Publication Number Publication Date
DE2705883A1 true DE2705883A1 (de) 1977-08-18

Family

ID=24638794

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19772705883 Withdrawn DE2705883A1 (de) 1976-02-13 1977-02-11 Neue anti-hypertonische zubereitungen

Country Status (10)

Country Link
US (2) US4051251A (enExample)
JP (1) JPS5299225A (enExample)
AU (1) AU513541B2 (enExample)
BE (1) BE851052A (enExample)
DE (1) DE2705883A1 (enExample)
FR (1) FR2340732A1 (enExample)
GB (1) GB1526172A (enExample)
NL (1) NL7700944A (enExample)
NZ (1) NZ183226A (enExample)
ZA (1) ZA77814B (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4070478A (en) * 1977-02-17 1978-01-24 Merck & Co., Inc. Benzimidazole substituted alanines
US4401676A (en) * 1977-06-01 1983-08-30 Merck & Co., Inc. Novel α-amino acids
WO2004052841A1 (en) * 2002-12-06 2004-06-24 Xenoport, Inc. Carbidopa prodrugs and uses thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3462536A (en) * 1960-07-22 1969-08-19 Merck & Co Inc Method of inhibiting decarboxylase
US3839585A (en) * 1970-08-05 1974-10-01 Merck & Co Inc Method of treating hypertension
AU464903B2 (en) * 1970-11-12 1975-09-11 Merck & Co., Inc Treatment of hypertension

Also Published As

Publication number Publication date
NZ183226A (en) 1980-03-05
NL7700944A (nl) 1977-08-16
FR2340732B1 (enExample) 1979-08-24
FR2340732A1 (fr) 1977-09-09
AU2191977A (en) 1978-08-10
ZA77814B (en) 1978-09-27
US4069333A (en) 1978-01-17
JPS5299225A (en) 1977-08-19
GB1526172A (en) 1978-09-27
US4051251A (en) 1977-09-27
AU513541B2 (en) 1980-12-11
BE851052A (fr) 1977-08-03

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Legal Events

Date Code Title Description
8139 Disposal/non-payment of the annual fee