JPS5299225A - Novel antiihypertension composition - Google Patents

Novel antiihypertension composition

Info

Publication number
JPS5299225A
JPS5299225A JP1308077A JP1308077A JPS5299225A JP S5299225 A JPS5299225 A JP S5299225A JP 1308077 A JP1308077 A JP 1308077A JP 1308077 A JP1308077 A JP 1308077A JP S5299225 A JPS5299225 A JP S5299225A
Authority
JP
Japan
Prior art keywords
antiihypertension
novel
composition
novel antiihypertension
antiihypertension composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP1308077A
Other languages
English (en)
Japanese (ja)
Inventor
Ee Sutoon Kuremento
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of JPS5299225A publication Critical patent/JPS5299225A/ja
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • C07D263/54Benzoxazoles; Hydrogenated benzoxazoles
    • C07D263/58Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4151,2-Diazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42Oxazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D235/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/26Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP1308077A 1976-02-13 1977-02-10 Novel antiihypertension composition Pending JPS5299225A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/657,824 US4051251A (en) 1976-02-13 1976-02-13 Novel anti-hypertensive compositions

Publications (1)

Publication Number Publication Date
JPS5299225A true JPS5299225A (en) 1977-08-19

Family

ID=24638794

Family Applications (1)

Application Number Title Priority Date Filing Date
JP1308077A Pending JPS5299225A (en) 1976-02-13 1977-02-10 Novel antiihypertension composition

Country Status (10)

Country Link
US (2) US4051251A (enExample)
JP (1) JPS5299225A (enExample)
AU (1) AU513541B2 (enExample)
BE (1) BE851052A (enExample)
DE (1) DE2705883A1 (enExample)
FR (1) FR2340732A1 (enExample)
GB (1) GB1526172A (enExample)
NL (1) NL7700944A (enExample)
NZ (1) NZ183226A (enExample)
ZA (1) ZA77814B (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4070478A (en) * 1977-02-17 1978-01-24 Merck & Co., Inc. Benzimidazole substituted alanines
US4401676A (en) * 1977-06-01 1983-08-30 Merck & Co., Inc. Novel α-amino acids
AU2003293423A1 (en) * 2002-12-06 2004-06-30 Xenoport, Inc. Carbidopa prodrugs and uses thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3462536A (en) * 1960-07-22 1969-08-19 Merck & Co Inc Method of inhibiting decarboxylase
US3839585A (en) * 1970-08-05 1974-10-01 Merck & Co Inc Method of treating hypertension
AU464903B2 (en) * 1970-11-12 1975-09-11 Merck & Co., Inc Treatment of hypertension

Also Published As

Publication number Publication date
FR2340732A1 (fr) 1977-09-09
AU513541B2 (en) 1980-12-11
AU2191977A (en) 1978-08-10
GB1526172A (en) 1978-09-27
NZ183226A (en) 1980-03-05
US4051251A (en) 1977-09-27
ZA77814B (en) 1978-09-27
FR2340732B1 (enExample) 1979-08-24
US4069333A (en) 1978-01-17
BE851052A (fr) 1977-08-03
NL7700944A (nl) 1977-08-16
DE2705883A1 (de) 1977-08-18

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