DE2646459A1 - Verteilvorrichtung und mit dieser versehene blutdialysevorrichtung - Google Patents
Verteilvorrichtung und mit dieser versehene blutdialysevorrichtungInfo
- Publication number
- DE2646459A1 DE2646459A1 DE19762646459 DE2646459A DE2646459A1 DE 2646459 A1 DE2646459 A1 DE 2646459A1 DE 19762646459 DE19762646459 DE 19762646459 DE 2646459 A DE2646459 A DE 2646459A DE 2646459 A1 DE2646459 A1 DE 2646459A1
- Authority
- DE
- Germany
- Prior art keywords
- flow
- distributor
- blood
- liquid
- inlet
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000008280 blood Substances 0.000 title claims description 69
- 210000004369 blood Anatomy 0.000 title claims description 69
- 238000009826 distribution Methods 0.000 title claims description 63
- 238000000502 dialysis Methods 0.000 title claims description 9
- 239000007788 liquid Substances 0.000 claims description 71
- 230000017531 blood circulation Effects 0.000 claims description 17
- 239000012530 fluid Substances 0.000 claims description 17
- 239000004033 plastic Substances 0.000 claims description 10
- 229920003023 plastic Polymers 0.000 claims description 10
- 230000007423 decrease Effects 0.000 claims description 9
- 230000002829 reductive effect Effects 0.000 claims description 9
- 230000008859 change Effects 0.000 claims description 4
- 229920001971 elastomer Polymers 0.000 claims description 3
- 239000005060 rubber Substances 0.000 claims description 3
- 239000002131 composite material Substances 0.000 claims description 2
- 229920001558 organosilicon polymer Polymers 0.000 claims description 2
- 230000000472 traumatic effect Effects 0.000 claims description 2
- 238000012423 maintenance Methods 0.000 claims 1
- 210000003734 kidney Anatomy 0.000 description 30
- CVSVTCORWBXHQV-UHFFFAOYSA-N creatine Chemical compound NC(=[NH2+])N(C)CC([O-])=O CVSVTCORWBXHQV-UHFFFAOYSA-N 0.000 description 18
- 238000012360 testing method Methods 0.000 description 18
- 238000010276 construction Methods 0.000 description 15
- 238000002474 experimental method Methods 0.000 description 13
- 238000012546 transfer Methods 0.000 description 13
- 102000009123 Fibrin Human genes 0.000 description 11
- 108010073385 Fibrin Proteins 0.000 description 11
- BWGVNKXGVNDBDI-UHFFFAOYSA-N Fibrin monomer Chemical group CNC(=O)CNC(=O)CN BWGVNKXGVNDBDI-UHFFFAOYSA-N 0.000 description 11
- 229950003499 fibrin Drugs 0.000 description 11
- 241000282472 Canis lupus familiaris Species 0.000 description 9
- 239000006046 creatine Substances 0.000 description 9
- 229960003624 creatine Drugs 0.000 description 9
- 238000013461 design Methods 0.000 description 9
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 8
- 208000007536 Thrombosis Diseases 0.000 description 8
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 8
- 239000004202 carbamide Substances 0.000 description 8
- 230000035602 clotting Effects 0.000 description 8
- 238000000034 method Methods 0.000 description 7
- 230000007704 transition Effects 0.000 description 7
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 description 6
- 230000015572 biosynthetic process Effects 0.000 description 6
- 241001465754 Metazoa Species 0.000 description 5
- 150000001875 compounds Chemical class 0.000 description 5
- 239000012528 membrane Substances 0.000 description 5
- 229920000260 silastic Polymers 0.000 description 5
- 235000002639 sodium chloride Nutrition 0.000 description 5
- 239000011780 sodium chloride Substances 0.000 description 5
- 206010053567 Coagulopathies Diseases 0.000 description 3
- 230000023555 blood coagulation Effects 0.000 description 3
- 239000001913 cellulose Substances 0.000 description 3
- 229920002678 cellulose Polymers 0.000 description 3
- 230000003247 decreasing effect Effects 0.000 description 3
- 230000008021 deposition Effects 0.000 description 3
- 239000012535 impurity Substances 0.000 description 3
- 238000001727 in vivo Methods 0.000 description 3
- 238000004382 potting Methods 0.000 description 3
- 238000000926 separation method Methods 0.000 description 3
- 206010018910 Haemolysis Diseases 0.000 description 2
- 102000001554 Hemoglobins Human genes 0.000 description 2
- 108010054147 Hemoglobins Proteins 0.000 description 2
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 description 2
- 239000005708 Sodium hypochlorite Substances 0.000 description 2
- 230000036772 blood pressure Effects 0.000 description 2
- 238000009530 blood pressure measurement Methods 0.000 description 2
- 230000036770 blood supply Effects 0.000 description 2
- 230000001419 dependent effect Effects 0.000 description 2
- 239000012153 distilled water Substances 0.000 description 2
- 238000001631 haemodialysis Methods 0.000 description 2
- 238000005534 hematocrit Methods 0.000 description 2
- 230000000322 hemodialysis Effects 0.000 description 2
- 230000008588 hemolysis Effects 0.000 description 2
- 229960002897 heparin Drugs 0.000 description 2
- 229920000669 heparin Polymers 0.000 description 2
- 238000001802 infusion Methods 0.000 description 2
- 238000011835 investigation Methods 0.000 description 2
- 238000005259 measurement Methods 0.000 description 2
- 230000007246 mechanism Effects 0.000 description 2
- 229920003229 poly(methyl methacrylate) Polymers 0.000 description 2
- SUKJFIGYRHOWBL-UHFFFAOYSA-N sodium hypochlorite Chemical compound [Na+].Cl[O-] SUKJFIGYRHOWBL-UHFFFAOYSA-N 0.000 description 2
- 238000009827 uniform distribution Methods 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- FGRBYDKOBBBPOI-UHFFFAOYSA-N 10,10-dioxo-2-[4-(N-phenylanilino)phenyl]thioxanthen-9-one Chemical compound O=C1c2ccccc2S(=O)(=O)c2ccc(cc12)-c1ccc(cc1)N(c1ccccc1)c1ccccc1 FGRBYDKOBBBPOI-UHFFFAOYSA-N 0.000 description 1
- 229920002972 Acrylic fiber Polymers 0.000 description 1
- 239000004925 Acrylic resin Substances 0.000 description 1
- 229920000178 Acrylic resin Polymers 0.000 description 1
- 206010067484 Adverse reaction Diseases 0.000 description 1
- 229920001747 Cellulose diacetate Polymers 0.000 description 1
- 229910019142 PO4 Inorganic materials 0.000 description 1
- NIXOWILDQLNWCW-UHFFFAOYSA-N acrylic acid group Chemical group C(C=C)(=O)O NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 230000006838 adverse reaction Effects 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 239000003146 anticoagulant agent Substances 0.000 description 1
- 210000001601 blood-air barrier Anatomy 0.000 description 1
- 230000036760 body temperature Effects 0.000 description 1
- 238000009529 body temperature measurement Methods 0.000 description 1
- 230000004087 circulation Effects 0.000 description 1
- 230000008094 contradictory effect Effects 0.000 description 1
- 230000006866 deterioration Effects 0.000 description 1
- 238000009792 diffusion process Methods 0.000 description 1
- 238000002224 dissection Methods 0.000 description 1
- 238000013100 final test Methods 0.000 description 1
- 238000011010 flushing procedure Methods 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 230000002489 hematologic effect Effects 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 230000002427 irreversible effect Effects 0.000 description 1
- 208000017169 kidney disease Diseases 0.000 description 1
- 230000002045 lasting effect Effects 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 230000013011 mating Effects 0.000 description 1
- 238000011089 mechanical engineering Methods 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 230000000414 obstructive effect Effects 0.000 description 1
- 238000004806 packaging method and process Methods 0.000 description 1
- 230000001575 pathological effect Effects 0.000 description 1
- 230000035515 penetration Effects 0.000 description 1
- 230000035699 permeability Effects 0.000 description 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 1
- 239000010452 phosphate Substances 0.000 description 1
- 239000002504 physiological saline solution Substances 0.000 description 1
- 239000004926 polymethyl methacrylate Substances 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 230000002441 reversible effect Effects 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 230000002459 sustained effect Effects 0.000 description 1
- 229920003051 synthetic elastomer Polymers 0.000 description 1
- 239000005061 synthetic rubber Substances 0.000 description 1
- 210000002435 tendon Anatomy 0.000 description 1
- 229920001169 thermoplastic Polymers 0.000 description 1
- 239000004416 thermosoftening plastic Substances 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 238000002054 transplantation Methods 0.000 description 1
- 238000000108 ultra-filtration Methods 0.000 description 1
- 238000012800 visualization Methods 0.000 description 1
- 238000004078 waterproofing Methods 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D63/00—Apparatus in general for separation processes using semi-permeable membranes
- B01D63/02—Hollow fibre modules
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D65/00—Accessories or auxiliary operations, in general, for separation processes or apparatus using semi-permeable membranes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2313/00—Details relating to membrane modules or apparatus
- B01D2313/10—Specific supply elements
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2313/00—Details relating to membrane modules or apparatus
- B01D2313/21—Specific headers, end caps
Landscapes
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- External Artificial Organs (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/622,418 US4038191A (en) | 1975-10-14 | 1975-10-14 | Manifold for ultra filtration machine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE2646459A1 true DE2646459A1 (de) | 1977-04-28 |
Family
ID=24494099
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE19762646459 Pending DE2646459A1 (de) | 1975-10-14 | 1976-10-14 | Verteilvorrichtung und mit dieser versehene blutdialysevorrichtung |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US4038191A (OSRAM) |
| JP (1) | JPS5284898A (OSRAM) |
| BR (1) | BR7606886A (OSRAM) |
| DE (1) | DE2646459A1 (OSRAM) |
| FR (1) | FR2327810A1 (OSRAM) |
| GB (1) | GB1559203A (OSRAM) |
| IT (1) | IT1068900B (OSRAM) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2646358C2 (de) * | 1976-10-14 | 1982-05-13 | Dr. Eduard Fresenius, Chemisch-pharmazeutische Industrie KG Apparatebau KG, 6380 Bad Homburg | Hohlfaserdialysator |
| SE422000B (sv) * | 1977-10-17 | 1982-02-15 | Gambro Dialysatoren | Anordning for diffusion och/eller filtration av emnen mellan tva fluider via semipermeabla membran vilken anordning innefattar en stapel av kamrar bildande ramar sammanhallen av spennmedel |
| SE421998B (sv) * | 1977-10-17 | 1982-02-15 | Gambro Dialysatoren | Anordning for diffusion och/eller filtration av emnen mellan tva fluider via semipermiabla membran vilken anordning innefattar en stapel av kamrar bildande ramar sammanhallen av u-formade endstycken |
| US4349440A (en) * | 1977-11-21 | 1982-09-14 | Esmond William G | Capillary tube exchange device |
| CA1144835A (en) * | 1978-05-30 | 1983-04-19 | Baxter Travenol Laboratories, Inc. | Cardiotomy reservoir |
| US4243531A (en) * | 1978-05-30 | 1981-01-06 | Baxter Travenol Laboratories, Inc. | Cardiotomy reservoir |
| US4425234A (en) * | 1979-07-30 | 1984-01-10 | Hospal Ltd. | Hollow fiber separatory device |
| US4640820A (en) * | 1983-10-28 | 1987-02-03 | Cardiovascular Devices, Inc. | Flow-through housing with blood gas sensors |
| US5133862A (en) * | 1991-01-31 | 1992-07-28 | Fmc Corporation | Flexible membrane diffuser |
| US5798041A (en) * | 1995-09-06 | 1998-08-25 | Hemasure, Inc. | In-line liquid filtration device useable for blood, blood products or the like |
| US6251292B1 (en) | 1994-03-10 | 2001-06-26 | Hemasure, Inc. | Method of preventing air from becoming entrapped within a filtration device |
| US6010633A (en) * | 1997-03-06 | 2000-01-04 | Hemasure Inc. | Method of preventing air from becoming entrapped within a filtration device |
| US5641458A (en) * | 1995-06-15 | 1997-06-24 | Shockley, Jr.; H. David | Flow through cell assembly |
| NL1004489C2 (nl) * | 1996-11-11 | 1998-05-14 | X Flow Bv | Filtratiemembraanmodule. |
| USD488599S1 (en) | 2000-06-05 | 2004-04-13 | Akram E. Chika | Blower nozzle |
| CN1331576C (zh) * | 2002-06-26 | 2007-08-15 | 布克-盖耶股份公司 | 用于横流过滤的装置 |
| US20100125235A1 (en) * | 2008-06-16 | 2010-05-20 | Triaxis Medical Devices, Inc. | Blood Treatment Apparatus Having Branched Flow Distribution |
| KR20100001493A (ko) * | 2008-06-27 | 2010-01-06 | 주식회사 코오롱 | 여과막 모듈용 헤더 및 그것을 이용한 여과막 모듈 |
| EP2477709A4 (en) * | 2009-09-14 | 2013-06-05 | Univ Columbia | Filter blood fluid channel methods, devices and systems |
| FR2972500B1 (fr) | 2011-03-10 | 2015-05-08 | Valeo Systemes Thermiques | Boitier d'admission comprenant un echangeur thermique |
| FR2972491B1 (fr) * | 2011-03-10 | 2013-03-29 | Valeo Systemes Thermiques | Couvercle d'un boitier d'admission |
| US9421315B2 (en) * | 2012-09-05 | 2016-08-23 | The Charles Stark Draper Laboratory, Inc. | Compact hydraulic manifold structure for shear sensitive fluids |
| US9656212B2 (en) * | 2013-01-08 | 2017-05-23 | The Charles Stark Draper Laboratory, Inc. | Compact hydraulic manifold structure for shear sensitive fluids |
| CN103389005B (zh) * | 2013-08-06 | 2015-08-05 | 杭州三花微通道换热器有限公司 | 制冷剂分配装置和具有它的换热器 |
| EP3131663A2 (en) | 2014-03-29 | 2017-02-22 | Princeton Trade and Technology Inc. | Blood processing cartridges and systems, and methods for extracorporeal blood therapies |
| US10426884B2 (en) | 2015-06-26 | 2019-10-01 | Novaflux Inc. | Cartridges and systems for outside-in flow in membrane-based therapies |
| US10399040B2 (en) | 2015-09-24 | 2019-09-03 | Novaflux Inc. | Cartridges and systems for membrane-based therapies |
| EP3348947B1 (en) * | 2017-01-13 | 2020-11-04 | HS Marston Aerospace Limited | Heat exchanger |
| CA3068008A1 (en) | 2017-06-21 | 2018-12-27 | The Regents Of The University Of California | Hemofilter for in vivo blood filtration |
| EP3546057A1 (en) * | 2018-03-28 | 2019-10-02 | National Oilwell Varco Norway AS | Device for processing water and methods |
| CN116173737B (zh) * | 2023-02-27 | 2023-11-03 | 山东瑞林达环保科技有限公司 | 一种一体式卷式分离膜元件 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US1830393A (en) * | 1928-05-16 | 1931-11-03 | Bernard A Geurink | Gas burner |
| US2573144A (en) * | 1946-03-22 | 1951-10-30 | Syncromatic Corp | Slotted outlet gas burner head |
| US3412940A (en) * | 1966-06-13 | 1968-11-26 | Luciano Ferroli Tredicesimo | Burner for town gas, liquefied gas, natural gas and mixtures thereof, and adapted to be fitted on boilers, stoves, air heaters and the like |
| FR1531361A (fr) * | 1966-09-21 | 1968-07-05 | Perfectionnements aux évaporateurs | |
| US3778369A (en) * | 1972-02-03 | 1973-12-11 | Atomic Energy Commission | Hemodialyzer with tapered slit blood ports and baffles |
-
1975
- 1975-10-14 US US05/622,418 patent/US4038191A/en not_active Expired - Lifetime
-
1976
- 1976-10-13 GB GB42597/76A patent/GB1559203A/en not_active Expired
- 1976-10-14 DE DE19762646459 patent/DE2646459A1/de active Pending
- 1976-10-14 JP JP12336776A patent/JPS5284898A/ja active Pending
- 1976-10-14 BR BR7606886A patent/BR7606886A/pt unknown
- 1976-10-14 IT IT28315/76A patent/IT1068900B/it active
- 1976-10-14 FR FR7630901A patent/FR2327810A1/fr active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| FR2327810A1 (fr) | 1977-05-13 |
| IT1068900B (it) | 1985-03-21 |
| GB1559203A (en) | 1980-01-16 |
| US4038191A (en) | 1977-07-26 |
| FR2327810B3 (OSRAM) | 1979-06-22 |
| BR7606886A (pt) | 1977-08-30 |
| JPS5284898A (en) | 1977-07-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| OHJ | Non-payment of the annual fee |