DE2604718A1 - Therapeutische vorrichtung zur verabreichung von skopolaminbase - Google Patents

Therapeutische vorrichtung zur verabreichung von skopolaminbase

Info

Publication number
DE2604718A1
DE2604718A1 DE19762604718 DE2604718A DE2604718A1 DE 2604718 A1 DE2604718 A1 DE 2604718A1 DE 19762604718 DE19762604718 DE 19762604718 DE 2604718 A DE2604718 A DE 2604718A DE 2604718 A1 DE2604718 A1 DE 2604718A1
Authority
DE
Germany
Prior art keywords
layer
scopolamine
polyisobutene
skin
membrane
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
DE19762604718
Other languages
German (de)
English (en)
Other versions
DE2604718C2 (de
Inventor
Santosh Kumar Chandrasekaran
Jane Elizabeth Shaw
John Urquhart
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alza Corp
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Publication of DE2604718A1 publication Critical patent/DE2604718A1/de
Application granted granted Critical
Publication of DE2604718C2 publication Critical patent/DE2604718C2/de
Expired legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B7/00—Layered products characterised by the relation between layers; Layered products characterised by the relative orientation of features between layers, or by the relative values of a measurable parameter between layers, i.e. products comprising layers having different physical, chemical or physicochemical properties; Layered products characterised by the interconnection of layers
    • B32B7/04—Interconnection of layers
    • B32B7/12—Interconnection of layers using interposed adhesives or interposed materials with bonding properties
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B27/00—Layered products comprising a layer of synthetic resin
    • B32B27/06—Layered products comprising a layer of synthetic resin as the main or only constituent of a layer, which is next to another layer of the same or of a different material
    • B32B27/08—Layered products comprising a layer of synthetic resin as the main or only constituent of a layer, which is next to another layer of the same or of a different material of synthetic resin
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B27/00—Layered products comprising a layer of synthetic resin
    • B32B27/32—Layered products comprising a layer of synthetic resin comprising polyolefins
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B27/00—Layered products comprising a layer of synthetic resin
    • B32B27/36—Layered products comprising a layer of synthetic resin comprising polyesters
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B2307/00—Properties of the layers or laminate
    • B32B2307/70—Other properties
    • B32B2307/726—Permeability to liquids, absorption
    • B32B2307/7265—Non-permeable
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B2323/00—Polyalkenes
    • B32B2323/10—Polypropylene
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B2367/00—Polyesters, e.g. PET, i.e. polyethylene terephthalate
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B2556/00—Patches, e.g. medical patches, repair patches

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Emergency Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Medical Uses (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE2604718A 1975-02-06 1976-02-06 Therapeutische Vorrichtung zur Verabreichung von Skopolaminbase und Verfahren zu deren Herstellung Expired DE2604718C2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US54750475A 1975-02-06 1975-02-06

Publications (2)

Publication Number Publication Date
DE2604718A1 true DE2604718A1 (de) 1976-08-19
DE2604718C2 DE2604718C2 (de) 1987-03-05

Family

ID=24184910

Family Applications (1)

Application Number Title Priority Date Filing Date
DE2604718A Expired DE2604718C2 (de) 1975-02-06 1976-02-06 Therapeutische Vorrichtung zur Verabreichung von Skopolaminbase und Verfahren zu deren Herstellung

Country Status (17)

Country Link
JP (1) JPS6049601B2 (nl)
AR (1) AR207805A1 (nl)
AT (1) AT344326B (nl)
AU (1) AU497383B2 (nl)
BE (1) BE838295A (nl)
CA (1) CA1059909A (nl)
CH (1) CH624848A5 (nl)
DE (1) DE2604718C2 (nl)
DK (1) DK145284C (nl)
ES (1) ES444552A1 (nl)
FR (1) FR2299853A1 (nl)
GB (1) GB1511121A (nl)
IL (1) IL48840A (nl)
IT (1) IT1057132B (nl)
NL (1) NL187379C (nl)
SE (1) SE424957B (nl)
ZA (1) ZA76234B (nl)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2755661A1 (de) * 1977-07-12 1979-01-25 Alza Corp Therapeutisches system fuer die transdermale anwendung von clonidin und verfahren zu dessen herstellung
EP0117027A1 (en) * 1983-01-18 1984-08-29 ELAN CORPORATION, Plc Drug delivery device
EP0150426A2 (de) * 1983-12-28 1985-08-07 Bayer Ag Wirkstoffabgabesysteme
DE3423328A1 (de) * 1984-06-23 1986-01-02 Beiersdorf Ag, 2000 Hamburg Selbstklebendes pflaster
US4711781A (en) * 1984-06-23 1987-12-08 Erich Nick Medicinal self-adhesive plaster
EP0249475A2 (en) * 1986-06-13 1987-12-16 Alza Corporation Delayed percutaneous delivery
EP0285563A1 (de) 1987-04-02 1988-10-05 Ciba-Geigy Ag Transdermale therapeutische Systeme für Wirkstoffkombinationen
DE4342174C1 (de) * 1993-12-10 1995-05-11 Lohmann Therapie Syst Lts Transdermales therapeutisches System sowie ein Verfahren zur Herstellung eines transdermalen therapeutischen Systems zur kombinierten transdermalen Anwendung von Physostigmin und Scopolamin für die Prophylaxe und zur Vorbehandlung einer Vergiftung durch hochtoxische phosphororganische Nervengifte, insbesondere Soman und seine Verwendung

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5621589Y2 (nl) * 1977-05-30 1981-05-21
JPS5843368B2 (ja) * 1980-10-30 1983-09-27 日東電工株式会社 消炎鎮痛貼付剤
JPS5942314A (ja) * 1982-08-31 1984-03-08 Nitto Electric Ind Co Ltd 外用部材
JPS5984816A (ja) * 1982-11-08 1984-05-16 Sekisui Chem Co Ltd 薬剤徐放性製剤
JPS6016916A (ja) * 1983-07-08 1985-01-28 Nitto Electric Ind Co Ltd 生物活性物質含有基剤及び該基剤の製法
US4588580B2 (en) * 1984-07-23 1999-02-16 Alaz Corp Transdermal administration of fentanyl and device therefor
IL72684A (en) * 1984-08-14 1989-02-28 Israel State Pharmaceutical compositions for controlled transdermal delivery of cholinergic or anticholinergic basic drugs
US4532244A (en) * 1984-09-06 1985-07-30 Innes Margaret N Method of treating migraine headaches
FR2599976A1 (fr) * 1986-06-16 1987-12-18 Michel Pistor Dispositif therapeutique, portable, totalement autonome, transdermique, pourvu d'au moins un organe formant aiguille ou pointe franchissant la barriere cutanee
GB8700150D0 (en) * 1987-01-06 1987-02-11 Martin I F Wound dressings
GB2212063A (en) * 1987-11-12 1989-07-19 Original Norfolk Trading Co Lt Application of chemicals such as systemic herbicides and insecticides
FR2623718B1 (fr) * 1987-11-27 1994-04-15 Fabre Medicament Pierre Dispositif therapeutique transdermique et son procede de preparation
DE3823395A1 (de) * 1988-07-09 1990-03-15 Holzapfel Boeving Partner Werb Mit einem wirkstoff getraenktes tuch

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2006696A1 (de) * 1969-02-13 1970-09-17 N.V. Organon, Oss (Niederlande) Pflaster oder Haftverband
US3767786A (en) * 1961-04-20 1973-10-23 Procter & Gamble Inhibiting perspiration with scopolamine esters
US3797494A (en) * 1969-04-01 1974-03-19 Alza Corp Bandage for the administration of drug by controlled metering through microporous materials
US3803300A (en) * 1970-03-18 1974-04-09 H Pospischil Ointment foil and method of preparing the same

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3767786A (en) * 1961-04-20 1973-10-23 Procter & Gamble Inhibiting perspiration with scopolamine esters
DE2006696A1 (de) * 1969-02-13 1970-09-17 N.V. Organon, Oss (Niederlande) Pflaster oder Haftverband
US3797494A (en) * 1969-04-01 1974-03-19 Alza Corp Bandage for the administration of drug by controlled metering through microporous materials
US3803300A (en) * 1970-03-18 1974-04-09 H Pospischil Ointment foil and method of preparing the same

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2755661A1 (de) * 1977-07-12 1979-01-25 Alza Corp Therapeutisches system fuer die transdermale anwendung von clonidin und verfahren zu dessen herstellung
EP0117027A1 (en) * 1983-01-18 1984-08-29 ELAN CORPORATION, Plc Drug delivery device
EP0150426A2 (de) * 1983-12-28 1985-08-07 Bayer Ag Wirkstoffabgabesysteme
US4661104A (en) * 1983-12-28 1987-04-28 Bayer Aktiengesellschaft Active compound release systems
EP0150426B1 (de) * 1983-12-28 1990-10-31 Bayer Ag Wirkstoffabgabesysteme
DE3423328A1 (de) * 1984-06-23 1986-01-02 Beiersdorf Ag, 2000 Hamburg Selbstklebendes pflaster
US4711781A (en) * 1984-06-23 1987-12-08 Erich Nick Medicinal self-adhesive plaster
EP0249475A2 (en) * 1986-06-13 1987-12-16 Alza Corporation Delayed percutaneous delivery
EP0249475A3 (en) * 1986-06-13 1989-10-11 Alza Corporation Delayed percutaneous delivery
EP0285563A1 (de) 1987-04-02 1988-10-05 Ciba-Geigy Ag Transdermale therapeutische Systeme für Wirkstoffkombinationen
DE4342174C1 (de) * 1993-12-10 1995-05-11 Lohmann Therapie Syst Lts Transdermales therapeutisches System sowie ein Verfahren zur Herstellung eines transdermalen therapeutischen Systems zur kombinierten transdermalen Anwendung von Physostigmin und Scopolamin für die Prophylaxe und zur Vorbehandlung einer Vergiftung durch hochtoxische phosphororganische Nervengifte, insbesondere Soman und seine Verwendung

Also Published As

Publication number Publication date
NL187379C (nl) 1991-09-16
IL48840A (en) 1978-01-31
JPS6049601B2 (ja) 1985-11-02
IL48840A0 (en) 1976-03-31
SE424957B (sv) 1982-08-23
DE2604718C2 (de) 1987-03-05
GB1511121A (en) 1978-05-17
BE838295A (fr) 1976-05-28
FR2299853A1 (fr) 1976-09-03
ATA65676A (de) 1977-11-15
DK145284C (da) 1983-03-21
DK145284B (da) 1982-10-25
CA1059909A (en) 1979-08-07
AU497383B2 (en) 1978-12-14
CH624848A5 (en) 1981-08-31
FR2299853B1 (nl) 1978-08-18
DK47676A (da) 1976-08-07
NL7601248A (nl) 1976-08-10
ZA76234B (en) 1977-01-26
NL187379B (nl) 1991-04-16
JPS51104021A (nl) 1976-09-14
ES444552A1 (es) 1977-08-16
IT1057132B (it) 1982-03-10
AU1067876A (en) 1977-08-04
SE7601204L (sv) 1976-08-09
AR207805A1 (es) 1976-10-29
AT344326B (de) 1978-07-10

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Legal Events

Date Code Title Description
8110 Request for examination paragraph 44
D2 Grant after examination
8364 No opposition during term of opposition