DE2424334A1 - Verfahren zur herstellung neuer heterocyclischer verbindungen - Google Patents

Verfahren zur herstellung neuer heterocyclischer verbindungen

Info

Publication number
DE2424334A1
DE2424334A1 DE2424334A DE2424334A DE2424334A1 DE 2424334 A1 DE2424334 A1 DE 2424334A1 DE 2424334 A DE2424334 A DE 2424334A DE 2424334 A DE2424334 A DE 2424334A DE 2424334 A1 DE2424334 A1 DE 2424334A1
Authority
DE
Germany
Prior art keywords
formula
compounds
triazine
alkyl
carbon atoms
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE2424334A
Other languages
German (de)
English (en)
Inventor
Franz Troxler
Arnold Vogel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH725973A external-priority patent/CH581137A5/de
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of DE2424334A1 publication Critical patent/DE2424334A1/de
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/38—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/38—Nitrogen atoms
    • C07D231/40—Acylated on said nitrogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE2424334A 1973-05-22 1974-05-18 Verfahren zur herstellung neuer heterocyclischer verbindungen Pending DE2424334A1 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
CH725973A CH581137A5 (en) 1973-05-22 1973-05-22 Pyrazolo(1,5-a)-s-triazines - and their salts, with bronchospasmolytic activity
CH725773 1973-05-22
CH725873 1973-05-22
CH1694073 1973-12-04
CH442574 1974-03-29

Publications (1)

Publication Number Publication Date
DE2424334A1 true DE2424334A1 (de) 1974-12-19

Family

ID=27509197

Family Applications (1)

Application Number Title Priority Date Filing Date
DE2424334A Pending DE2424334A1 (de) 1973-05-22 1974-05-18 Verfahren zur herstellung neuer heterocyclischer verbindungen

Country Status (8)

Country Link
JP (1) JPS5019769A (zh)
AU (1) AU6925974A (zh)
DD (1) DD113907A5 (zh)
DE (1) DE2424334A1 (zh)
FI (1) FI146174A (zh)
FR (1) FR2230366A1 (zh)
IL (1) IL44873A0 (zh)
NL (1) NL7406641A (zh)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2900288A1 (de) * 1978-01-09 1979-07-12 Aron Sa Aminoderivate von pyrazol eckige klammer auf 1,5-a eckige klammer zu s-triazin, verfahren zu ihrer herstellung und sie enthaltende arzneimittel
DE3942357A1 (de) * 1989-12-21 1991-06-27 Boehringer Mannheim Gmbh 3-aminopyrazolo-heterocyclen, deren verwendung zur bestimmung von wasserstoffperoxid, wasserstoffperoxid-bildenden systemen, peroxidase, peroxidatisch wirksamen substanzen oder von elektronenreichen aromatischen verbindungen, entsprechende bestimmungsverfahren und hierfuer geeignete mittel
WO2011141713A1 (en) 2010-05-13 2011-11-17 Centro Nacional De Investigaciones Oncologicas (Cnio) New bicyclic compounds as pi3-k and mtor inhibitors
US8518931B2 (en) 2008-04-07 2013-08-27 Irm Llc Compounds and compositions as kinase inhibitors
US9073927B2 (en) 2010-01-22 2015-07-07 Fundacion Centro Nacional De Investigaciones Oncologicas Carlos Iii Inhibitors of PI3 kinase
WO2015193169A1 (en) * 2014-06-17 2015-12-23 Ucb Biopharma Sprl Fused bicyclic heteroaromatic derivatives as kinase inhibitors

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2842809A1 (fr) * 2002-07-26 2004-01-30 Greenpharma Sas NOUVELLES PYRAZOLO[1,5-a]-1,3,5-TRIAZINES SUBSTITUEES ET LEURS ANALOGUES, COMPOSITIONS PHARMACEUTIQUES LES CONTENANT, UTILISATION A TITRE DE MEDICAMENT ET PROCEDES POUR LEUR PREPARATION
FR2850653A1 (fr) * 2003-02-04 2004-08-06 Univ Pasteur Derives de pyrazolotriazine, procede de preparation et utilisations
EP1633756B1 (en) 2003-04-09 2008-12-24 Biogen Idec MA Inc. A2a adenosine receptor antagonists
US7674791B2 (en) 2003-04-09 2010-03-09 Biogen Idec Ma Inc. Triazolopyrazines and methods of making and using the same
WO2004092170A2 (en) * 2003-04-09 2004-10-28 Biogen Idec Ma Inc. Triazolotriazines and pyrazolotriazines useful as a2a adenosine receptor antagon ists
AR047969A1 (es) 2004-02-25 2006-03-15 Schering Corp Pirazolotriazinas como inhibidores de quinasa
JP2018199623A (ja) * 2015-10-22 2018-12-20 大正製薬株式会社 含窒素縮合複素環化合物
CN118284610A (zh) * 2021-11-23 2024-07-02 原真股份有限公司 用作cdk9抑制剂的吡唑并三嗪衍生物

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2900288A1 (de) * 1978-01-09 1979-07-12 Aron Sa Aminoderivate von pyrazol eckige klammer auf 1,5-a eckige klammer zu s-triazin, verfahren zu ihrer herstellung und sie enthaltende arzneimittel
DE3942357A1 (de) * 1989-12-21 1991-06-27 Boehringer Mannheim Gmbh 3-aminopyrazolo-heterocyclen, deren verwendung zur bestimmung von wasserstoffperoxid, wasserstoffperoxid-bildenden systemen, peroxidase, peroxidatisch wirksamen substanzen oder von elektronenreichen aromatischen verbindungen, entsprechende bestimmungsverfahren und hierfuer geeignete mittel
US8518931B2 (en) 2008-04-07 2013-08-27 Irm Llc Compounds and compositions as kinase inhibitors
US9073927B2 (en) 2010-01-22 2015-07-07 Fundacion Centro Nacional De Investigaciones Oncologicas Carlos Iii Inhibitors of PI3 kinase
WO2011141713A1 (en) 2010-05-13 2011-11-17 Centro Nacional De Investigaciones Oncologicas (Cnio) New bicyclic compounds as pi3-k and mtor inhibitors
WO2015193169A1 (en) * 2014-06-17 2015-12-23 Ucb Biopharma Sprl Fused bicyclic heteroaromatic derivatives as kinase inhibitors
CN106559992A (zh) * 2014-06-17 2017-04-05 Ucb生物制药私人有限公司 作为激酶抑制剂的稠合的二环杂芳族衍生物
US10000497B2 (en) 2014-06-17 2018-06-19 Ucb Biopharma Sprl Fused bicyclic heteroaromatic derivatives as kinase inhibitors

Also Published As

Publication number Publication date
FI146174A (zh) 1974-11-23
NL7406641A (zh) 1974-11-26
IL44873A0 (en) 1974-07-31
FR2230366A1 (en) 1974-12-20
AU6925974A (en) 1975-11-27
JPS5019769A (zh) 1975-03-01
FR2230366B1 (zh) 1977-11-10
DD113907A5 (zh) 1975-07-05

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