DE2359501A1 - Verfahren zur herstellung von mikroorganismen-lysaten - Google Patents
Verfahren zur herstellung von mikroorganismen-lysatenInfo
- Publication number
- DE2359501A1 DE2359501A1 DE2359501A DE2359501A DE2359501A1 DE 2359501 A1 DE2359501 A1 DE 2359501A1 DE 2359501 A DE2359501 A DE 2359501A DE 2359501 A DE2359501 A DE 2359501A DE 2359501 A1 DE2359501 A1 DE 2359501A1
- Authority
- DE
- Germany
- Prior art keywords
- microorganism
- autolysis
- water
- cells
- subjected
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 244000005700 microbiome Species 0.000 title claims description 31
- 238000000034 method Methods 0.000 title claims description 25
- 239000006166 lysate Substances 0.000 title claims description 6
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 20
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims description 16
- 208000035404 Autolysis Diseases 0.000 claims description 16
- 206010057248 Cell death Diseases 0.000 claims description 16
- 230000028043 self proteolysis Effects 0.000 claims description 16
- 238000001694 spray drying Methods 0.000 claims description 12
- 230000008569 process Effects 0.000 claims description 10
- 239000000725 suspension Substances 0.000 claims description 9
- 229910052757 nitrogen Inorganic materials 0.000 claims description 8
- 238000004519 manufacturing process Methods 0.000 claims description 6
- 239000007900 aqueous suspension Substances 0.000 claims description 4
- 238000002635 electroconvulsive therapy Methods 0.000 claims description 4
- 239000011261 inert gas Substances 0.000 claims description 3
- 239000007921 spray Substances 0.000 claims description 2
- 210000004027 cell Anatomy 0.000 description 32
- 240000004808 Saccharomyces cerevisiae Species 0.000 description 14
- 239000000047 product Substances 0.000 description 14
- 210000000805 cytoplasm Anatomy 0.000 description 13
- 238000001035 drying Methods 0.000 description 8
- 210000002421 cell wall Anatomy 0.000 description 7
- 235000013305 food Nutrition 0.000 description 7
- 235000015097 nutrients Nutrition 0.000 description 7
- 102000004169 proteins and genes Human genes 0.000 description 7
- 108090000623 proteins and genes Proteins 0.000 description 7
- 210000000170 cell membrane Anatomy 0.000 description 6
- 238000000855 fermentation Methods 0.000 description 5
- 230000004151 fermentation Effects 0.000 description 5
- 229930195733 hydrocarbon Natural products 0.000 description 5
- 150000002430 hydrocarbons Chemical class 0.000 description 5
- 150000002632 lipids Chemical class 0.000 description 5
- 150000003839 salts Chemical class 0.000 description 5
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 4
- 239000002253 acid Substances 0.000 description 4
- 229910052799 carbon Inorganic materials 0.000 description 4
- 238000003756 stirring Methods 0.000 description 4
- 102000004190 Enzymes Human genes 0.000 description 3
- 108090000790 Enzymes Proteins 0.000 description 3
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 3
- 150000001335 aliphatic alkanes Chemical class 0.000 description 3
- 230000002358 autolytic effect Effects 0.000 description 3
- 230000015556 catabolic process Effects 0.000 description 3
- 238000005119 centrifugation Methods 0.000 description 3
- 238000006731 degradation reaction Methods 0.000 description 3
- 230000007062 hydrolysis Effects 0.000 description 3
- 238000006460 hydrolysis reaction Methods 0.000 description 3
- 239000000203 mixture Substances 0.000 description 3
- 150000002894 organic compounds Chemical class 0.000 description 3
- 239000007787 solid Substances 0.000 description 3
- 241000894006 Bacteria Species 0.000 description 2
- 230000002378 acidificating effect Effects 0.000 description 2
- 239000007864 aqueous solution Substances 0.000 description 2
- 150000001875 compounds Chemical class 0.000 description 2
- 230000009089 cytolysis Effects 0.000 description 2
- 238000005189 flocculation Methods 0.000 description 2
- 230000016615 flocculation Effects 0.000 description 2
- 238000011534 incubation Methods 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 239000007791 liquid phase Substances 0.000 description 2
- 239000012528 membrane Substances 0.000 description 2
- 235000013379 molasses Nutrition 0.000 description 2
- 150000007523 nucleic acids Chemical class 0.000 description 2
- 102000039446 nucleic acids Human genes 0.000 description 2
- 108020004707 nucleic acids Proteins 0.000 description 2
- 238000000926 separation method Methods 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- LSNNMFCWUKXFEE-UHFFFAOYSA-L sulfite Chemical compound [O-]S([O-])=O LSNNMFCWUKXFEE-UHFFFAOYSA-L 0.000 description 2
- 239000006228 supernatant Substances 0.000 description 2
- 239000004094 surface-active agent Substances 0.000 description 2
- 239000002699 waste material Substances 0.000 description 2
- OILXMJHPFNGGTO-UHFFFAOYSA-N (22E)-(24xi)-24-methylcholesta-5,22-dien-3beta-ol Natural products C1C=C2CC(O)CCC2(C)C2C1C1CCC(C(C)C=CC(C)C(C)C)C1(C)CC2 OILXMJHPFNGGTO-UHFFFAOYSA-N 0.000 description 1
- RQOCXCFLRBRBCS-UHFFFAOYSA-N (22E)-cholesta-5,7,22-trien-3beta-ol Natural products C1C(O)CCC2(C)C(CCC3(C(C(C)C=CCC(C)C)CCC33)C)C3=CC=C21 RQOCXCFLRBRBCS-UHFFFAOYSA-N 0.000 description 1
- OQMZNAMGEHIHNN-UHFFFAOYSA-N 7-Dehydrostigmasterol Natural products C1C(O)CCC2(C)C(CCC3(C(C(C)C=CC(CC)C(C)C)CCC33)C)C3=CC=C21 OQMZNAMGEHIHNN-UHFFFAOYSA-N 0.000 description 1
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical class [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 1
- DNVPQKQSNYMLRS-NXVQYWJNSA-N Ergosterol Natural products CC(C)[C@@H](C)C=C[C@H](C)[C@H]1CC[C@H]2C3=CC=C4C[C@@H](O)CC[C@]4(C)[C@@H]3CC[C@]12C DNVPQKQSNYMLRS-NXVQYWJNSA-N 0.000 description 1
- 235000002918 Fraxinus excelsior Nutrition 0.000 description 1
- 230000005526 G1 to G0 transition Effects 0.000 description 1
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical class [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 description 1
- 229930182558 Sterol Natural products 0.000 description 1
- 241000235015 Yarrowia lipolytica Species 0.000 description 1
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical class [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 description 1
- 150000007513 acids Chemical class 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 239000008346 aqueous phase Substances 0.000 description 1
- 239000002956 ash Substances 0.000 description 1
- 235000013405 beer Nutrition 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 235000008429 bread Nutrition 0.000 description 1
- 239000011575 calcium Chemical class 0.000 description 1
- 229910052791 calcium Inorganic materials 0.000 description 1
- 150000001720 carbohydrates Chemical class 0.000 description 1
- 235000014633 carbohydrates Nutrition 0.000 description 1
- 125000004432 carbon atom Chemical group C* 0.000 description 1
- 230000010261 cell growth Effects 0.000 description 1
- 230000006037 cell lysis Effects 0.000 description 1
- 210000003850 cellular structure Anatomy 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 150000003841 chloride salts Chemical class 0.000 description 1
- 229930002875 chlorophyll Natural products 0.000 description 1
- 235000019804 chlorophyll Nutrition 0.000 description 1
- ATNHDLDRLWWWCB-AENOIHSZSA-M chlorophyll a Chemical compound C1([C@@H](C(=O)OC)C(=O)C2=C3C)=C2N2C3=CC(C(CC)=C3C)=[N+]4C3=CC3=C(C=C)C(C)=C5N3[Mg-2]42[N+]2=C1[C@@H](CCC(=O)OC\C=C(/C)CCC[C@H](C)CCC[C@H](C)CCCC(C)C)[C@H](C)C2=C5 ATNHDLDRLWWWCB-AENOIHSZSA-M 0.000 description 1
- 238000004587 chromatography analysis Methods 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 238000004040 coloring Methods 0.000 description 1
- 239000008367 deionised water Substances 0.000 description 1
- 229910021641 deionized water Inorganic materials 0.000 description 1
- 235000019621 digestibility Nutrition 0.000 description 1
- 238000004090 dissolution Methods 0.000 description 1
- 238000001962 electrophoresis Methods 0.000 description 1
- DNVPQKQSNYMLRS-SOWFXMKYSA-N ergosterol Chemical compound C1[C@@H](O)CC[C@]2(C)[C@H](CC[C@]3([C@H]([C@H](C)/C=C/[C@@H](C)C(C)C)CC[C@H]33)C)C3=CC=C21 DNVPQKQSNYMLRS-SOWFXMKYSA-N 0.000 description 1
- 238000001704 evaporation Methods 0.000 description 1
- 230000008020 evaporation Effects 0.000 description 1
- 239000000284 extract Substances 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 239000007789 gas Substances 0.000 description 1
- 239000008187 granular material Substances 0.000 description 1
- 230000012010 growth Effects 0.000 description 1
- 150000004820 halides Chemical class 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 150000002484 inorganic compounds Chemical class 0.000 description 1
- 229910010272 inorganic material Inorganic materials 0.000 description 1
- 229910017053 inorganic salt Inorganic materials 0.000 description 1
- 239000000543 intermediate Substances 0.000 description 1
- 230000003834 intracellular effect Effects 0.000 description 1
- 238000011031 large-scale manufacturing process Methods 0.000 description 1
- KBPHJBAIARWVSC-RGZFRNHPSA-N lutein Chemical compound C([C@H](O)CC=1C)C(C)(C)C=1\C=C\C(\C)=C\C=C\C(\C)=C\C=C\C=C(/C)\C=C\C=C(/C)\C=C\[C@H]1C(C)=C[C@H](O)CC1(C)C KBPHJBAIARWVSC-RGZFRNHPSA-N 0.000 description 1
- 229960005375 lutein Drugs 0.000 description 1
- 239000011777 magnesium Substances 0.000 description 1
- 229910052749 magnesium Inorganic materials 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 230000003204 osmotic effect Effects 0.000 description 1
- 239000012071 phase Substances 0.000 description 1
- 239000000049 pigment Substances 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 238000001556 precipitation Methods 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
- QEVHRUUCFGRFIF-MDEJGZGSSA-N reserpine Chemical compound O([C@H]1[C@@H]([C@H]([C@H]2C[C@@H]3C4=C(C5=CC=C(OC)C=C5N4)CCN3C[C@H]2C1)C(=O)OC)OC)C(=O)C1=CC(OC)=C(OC)C(OC)=C1 QEVHRUUCFGRFIF-MDEJGZGSSA-N 0.000 description 1
- 238000004062 sedimentation Methods 0.000 description 1
- 159000000000 sodium salts Chemical class 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 239000007858 starting material Substances 0.000 description 1
- 150000003432 sterols Chemical class 0.000 description 1
- 235000003702 sterols Nutrition 0.000 description 1
- 150000003467 sulfuric acid derivatives Chemical class 0.000 description 1
- KBPHJBAIARWVSC-XQIHNALSSA-N trans-lutein Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CC(O)CC1(C)C)C=CC=C(/C)C=CC2C(=CC(O)CC2(C)C)C KBPHJBAIARWVSC-XQIHNALSSA-N 0.000 description 1
- 235000013311 vegetables Nutrition 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- MECHNRXZTMCUDQ-RKHKHRCZSA-N vitamin D2 Chemical compound C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)/C=C/[C@H](C)C(C)C)=C\C=C1\C[C@@H](O)CCC1=C MECHNRXZTMCUDQ-RKHKHRCZSA-N 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
- 235000014101 wine Nutrition 0.000 description 1
- 239000002023 wood Substances 0.000 description 1
- FJHBOVDFOQMZRV-XQIHNALSSA-N xanthophyll Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CC(O)CC1(C)C)C=CC=C(/C)C=CC2C=C(C)C(O)CC2(C)C FJHBOVDFOQMZRV-XQIHNALSSA-N 0.000 description 1
- 235000008210 xanthophylls Nutrition 0.000 description 1
- 239000011701 zinc Chemical class 0.000 description 1
- 229910052725 zinc Chemical class 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/06—Lysis of microorganisms
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Virology (AREA)
- Microbiology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Mycology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT32277/72A IT982367B (it) | 1972-11-30 | 1972-11-30 | Procedimento per la produzione di lisati da microorganism |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE2359501A1 true DE2359501A1 (de) | 1974-06-27 |
Family
ID=11235091
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE2359501A Withdrawn DE2359501A1 (de) | 1972-11-30 | 1973-11-29 | Verfahren zur herstellung von mikroorganismen-lysaten |
Country Status (9)
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2837342A1 (de) * | 1978-08-26 | 1980-03-06 | Henkel Kgaa | Verfahren zur herstellung von hefeautolysat |
| US4288554A (en) * | 1979-12-20 | 1981-09-08 | Euteco Impianti S.P.A. | Process for the cultivation of yeast cells |
| US4830969A (en) * | 1981-08-31 | 1989-05-16 | The Research Foundation Of State University Of New York | Process for the rapid and simple isolation of nucleic acids |
| GB8604440D0 (en) * | 1986-02-22 | 1986-03-26 | Bovril Ltd | Process |
| US4728427A (en) * | 1986-10-14 | 1988-03-01 | Revis Nathaniel W | Reduction of trace elements to the elemental form by microorganisms |
| US4826602A (en) * | 1986-10-14 | 1989-05-02 | Oak Ridge Research Institute | Reduction of trace elements to the elemental form by microorganisms |
| BRPI0611535B1 (pt) * | 2005-05-05 | 2021-11-30 | Sensient Flavors Inc | Método para processar células de levedura para produzir beta-glucanos e mananas |
| FR3139515A1 (fr) | 2022-09-08 | 2024-03-15 | Psa Automobiles Sa | Vehicule automobile avec prise de recharge de batterie de traction sur un panneau arriere de custode |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2928740A (en) * | 1958-07-28 | 1960-03-15 | American Bio Synthetics Corp | Food flavoring composition and method of enhancing the flavor of foods |
| GB1196786A (en) * | 1967-11-23 | 1970-07-01 | Distillers Co Yeast Ltd | Yeast and method for its production |
| US3720585A (en) * | 1970-07-08 | 1973-03-13 | Massachusetts Inst Technology | Process of reducing the nucleic acid content in yeast |
-
1972
- 1972-11-30 IT IT32277/72A patent/IT982367B/it active
-
1973
- 1973-11-23 NL NL7316040A patent/NL7316040A/xx not_active Application Discontinuation
- 1973-11-26 GB GB5473173A patent/GB1424256A/en not_active Expired
- 1973-11-28 CA CA186,881A patent/CA987616A/en not_active Expired
- 1973-11-28 YU YU03099/73A patent/YU309973A/xx unknown
- 1973-11-29 FR FR7343303A patent/FR2208979B1/fr not_active Expired
- 1973-11-29 DE DE2359501A patent/DE2359501A1/de not_active Withdrawn
- 1973-11-29 US US05/420,346 patent/US3934039A/en not_active Expired - Lifetime
- 1973-11-29 JP JP48133994A patent/JPS5752830B2/ja not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| JPS5752830B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1982-11-10 |
| IT982367B (it) | 1974-10-21 |
| FR2208979B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1976-06-25 |
| GB1424256A (en) | 1976-02-11 |
| CA987616A (en) | 1976-04-20 |
| NL7316040A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1974-06-04 |
| US3934039A (en) | 1976-01-20 |
| JPS4981594A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1974-08-06 |
| FR2208979A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1974-06-28 |
| YU309973A (en) | 1982-06-30 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE2444849C2 (de) | Verfahren zur Herstellung organischer Säuren durch biologische Hydrolyse | |
| DE1800508B2 (de) | Verfahren zur herstellung von proteolytischen enzymaufbereitungen und ihre verwendung | |
| DE2161164C3 (de) | Verfahren zur mikrobiologischen Erzeugung von Proteinmassen und Verwendung des proteinhaltigen Produkts | |
| DE3405664A1 (de) | Verfahren zur biotechnischen herstellung von rhamnolipiden und rhamnolipide mit nur einem ss-hydroxidecancarbonsaeurerest im molekuel | |
| EP0144017B1 (de) | Verfahren zur biotechnologischen Herstellung von Poly-D(-)-3-hydroxybuttersäure | |
| CH645408A5 (de) | Verfahren zur herstellung von pectin aus pflanzengeweben. | |
| DE2359501A1 (de) | Verfahren zur herstellung von mikroorganismen-lysaten | |
| DE2229285A1 (de) | Verfahren zur extraktion von proteinen aus zellen von mikroorganismen | |
| DE2334463A1 (de) | Verfahren zur gewinnung von proteolytischen enzymen, die so hergestellten proteolytischen enzyme und ihre verwendung | |
| DE2402217C3 (de) | Verfahren zur Herstellung von Proteinmaterial | |
| DE2401519A1 (de) | Mikrobiologisches verfahren zur herstellung fluessigen und trockenen futterkonzentrates von l-lysin und kristallinen l-lysins | |
| DE69024910T2 (de) | Natürliche Delta-Lactone und Verfahren zu deren Herstellung | |
| DE2034593C3 (de) | Verfahren zur Herstellung von Zitronensäure | |
| DE2357345A1 (de) | Verfahren zur biotechnischen herstellung von hefe und deren verwendung | |
| DE3041224A1 (de) | Verfahren zur fermentativen herstellung von d(-)- (beta) -hydroxyisobuttersaeure | |
| DE2202701C3 (de) | Verfahren zur biotechnischen Herstellung von Zitronensäure | |
| DE2058371A1 (de) | Verfahren zur Herstellung von 6-Aminopenicillansaeure | |
| DE2659542A1 (de) | Verfahren zur reinigung von biomasse | |
| CH380133A (de) | Verfahren zur Herstellung von 6-Amino-Penicillansäure | |
| DE2142916A1 (de) | Verfahren zur Herstellung von Enzymen mit Hilfe von Kohlenwasserstoffen | |
| DE3545246A1 (de) | Verfahren zur herstellung von exozellulaeren biopolymeren mit verdickungswirkung fuer waessrige medien | |
| DE2134826A1 (de) | Verfahren zur Herstellung eines Citrat Isocitrat Gemisches | |
| DE1442051C3 (de) | Verfahren zur Züchtung und Reingewinnung von Mikroorganismen auf Kohlenwasserstofffraktionen | |
| DE2700698C3 (de) | Verfahren zur mikrobiologischen Gewinnung von Einzellerprotein auf Basis von Äthanol | |
| AT233168B (de) | Verfahren zur Herstellung des Antibiotikums ZN-6 und seiner Salze |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8141 | Disposal/no request for examination |