DE2246205A1 - Verfahren zur gewinnung eines extrakts aus arnica montana - Google Patents
Verfahren zur gewinnung eines extrakts aus arnica montanaInfo
- Publication number
- DE2246205A1 DE2246205A1 DE2246205A DE2246205A DE2246205A1 DE 2246205 A1 DE2246205 A1 DE 2246205A1 DE 2246205 A DE2246205 A DE 2246205A DE 2246205 A DE2246205 A DE 2246205A DE 2246205 A1 DE2246205 A1 DE 2246205A1
- Authority
- DE
- Germany
- Prior art keywords
- residue
- water
- extracted
- insoluble
- arnica montana
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000284 extract Substances 0.000 title claims description 28
- 238000000034 method Methods 0.000 title claims description 26
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical group CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 claims description 64
- XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 claims description 33
- HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 claims description 30
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 claims description 30
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 28
- 238000000605 extraction Methods 0.000 claims description 27
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 claims description 22
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 22
- 241000086254 Arnica montana Species 0.000 claims description 21
- 239000003208 petroleum Substances 0.000 claims description 17
- 239000002904 solvent Substances 0.000 claims description 16
- 239000000706 filtrate Substances 0.000 claims description 15
- 239000000203 mixture Substances 0.000 claims description 12
- 241000196324 Embryophyta Species 0.000 claims description 10
- IDGUHHHQCWSQLU-UHFFFAOYSA-N ethanol;hydrate Chemical compound O.CCO IDGUHHHQCWSQLU-UHFFFAOYSA-N 0.000 claims description 10
- 239000004480 active ingredient Substances 0.000 claims description 7
- 230000000694 effects Effects 0.000 claims description 7
- 239000008346 aqueous phase Substances 0.000 claims description 6
- 230000023555 blood coagulation Effects 0.000 claims description 4
- 239000012153 distilled water Substances 0.000 claims description 4
- 239000000839 emulsion Substances 0.000 claims description 3
- 229940002359 arnica montana extract Drugs 0.000 claims description 2
- 125000001033 ether group Chemical group 0.000 claims 2
- 241000254173 Coleoptera Species 0.000 claims 1
- 239000012736 aqueous medium Substances 0.000 claims 1
- 239000012141 concentrate Substances 0.000 claims 1
- 239000000047 product Substances 0.000 description 17
- 239000000126 substance Substances 0.000 description 10
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 9
- 230000015271 coagulation Effects 0.000 description 9
- 238000005345 coagulation Methods 0.000 description 9
- 239000000741 silica gel Substances 0.000 description 9
- 229910002027 silica gel Inorganic materials 0.000 description 9
- 239000000243 solution Substances 0.000 description 9
- 241000208983 Arnica Species 0.000 description 8
- 235000019441 ethanol Nutrition 0.000 description 7
- 210000002381 plasma Anatomy 0.000 description 7
- 239000000463 material Substances 0.000 description 6
- 230000001225 therapeutic effect Effects 0.000 description 5
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 4
- 230000023597 hemostasis Effects 0.000 description 4
- 208000007536 Thrombosis Diseases 0.000 description 3
- 210000004369 blood Anatomy 0.000 description 3
- 239000008280 blood Substances 0.000 description 3
- UREBWPXBXRYXRJ-UHFFFAOYSA-N ethyl acetate;methanol Chemical compound OC.CCOC(C)=O UREBWPXBXRYXRJ-UHFFFAOYSA-N 0.000 description 3
- 239000003527 fibrinolytic agent Substances 0.000 description 3
- 230000003480 fibrinolytic effect Effects 0.000 description 3
- 238000001914 filtration Methods 0.000 description 3
- 230000035876 healing Effects 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 3
- GBMDVOWEEQVZKZ-UHFFFAOYSA-N methanol;hydrate Chemical compound O.OC GBMDVOWEEQVZKZ-UHFFFAOYSA-N 0.000 description 3
- 239000012264 purified product Substances 0.000 description 3
- 229940098465 tincture Drugs 0.000 description 3
- 108090000190 Thrombin Proteins 0.000 description 2
- 230000002159 abnormal effect Effects 0.000 description 2
- 238000010521 absorption reaction Methods 0.000 description 2
- UCTWMZQNUQWSLP-UHFFFAOYSA-N adrenaline Chemical compound CNCC(O)C1=CC=C(O)C(O)=C1 UCTWMZQNUQWSLP-UHFFFAOYSA-N 0.000 description 2
- 230000001476 alcoholic effect Effects 0.000 description 2
- 229930013930 alkaloid Natural products 0.000 description 2
- FIMJSWFMQJGVAM-UHFFFAOYSA-N chloroform;hydrate Chemical compound O.ClC(Cl)Cl FIMJSWFMQJGVAM-UHFFFAOYSA-N 0.000 description 2
- 230000000052 comparative effect Effects 0.000 description 2
- 238000001816 cooling Methods 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 210000000416 exudates and transudate Anatomy 0.000 description 2
- 238000002347 injection Methods 0.000 description 2
- 239000007924 injection Substances 0.000 description 2
- 210000000653 nervous system Anatomy 0.000 description 2
- 238000003756 stirring Methods 0.000 description 2
- 229960004072 thrombin Drugs 0.000 description 2
- 231100000331 toxic Toxicity 0.000 description 2
- 230000002588 toxic effect Effects 0.000 description 2
- 231100000419 toxicity Toxicity 0.000 description 2
- 230000001988 toxicity Effects 0.000 description 2
- 102000008186 Collagen Human genes 0.000 description 1
- 108010035532 Collagen Proteins 0.000 description 1
- 208000034656 Contusions Diseases 0.000 description 1
- 206010014080 Ecchymosis Diseases 0.000 description 1
- 102000009123 Fibrin Human genes 0.000 description 1
- 108010073385 Fibrin Proteins 0.000 description 1
- BWGVNKXGVNDBDI-UHFFFAOYSA-N Fibrin monomer Chemical compound CNC(=O)CNC(=O)CN BWGVNKXGVNDBDI-UHFFFAOYSA-N 0.000 description 1
- 206010018852 Haematoma Diseases 0.000 description 1
- 206010021703 Indifference Diseases 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 241000699670 Mus sp. Species 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 230000004520 agglutination Effects 0.000 description 1
- 150000003797 alkaloid derivatives Chemical class 0.000 description 1
- 239000012223 aqueous fraction Substances 0.000 description 1
- 239000003125 aqueous solvent Substances 0.000 description 1
- 230000033228 biological regulation Effects 0.000 description 1
- 230000036772 blood pressure Effects 0.000 description 1
- 239000003610 charcoal Substances 0.000 description 1
- 239000007795 chemical reaction product Substances 0.000 description 1
- 238000004587 chromatography analysis Methods 0.000 description 1
- 238000005352 clarification Methods 0.000 description 1
- 229920001436 collagen Polymers 0.000 description 1
- 230000009089 cytolysis Effects 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 238000010790 dilution Methods 0.000 description 1
- 239000012895 dilution Substances 0.000 description 1
- 238000004090 dissolution Methods 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 238000001704 evaporation Methods 0.000 description 1
- 230000008020 evaporation Effects 0.000 description 1
- 229950003499 fibrin Drugs 0.000 description 1
- 230000001471 fibrinogenolytic effect Effects 0.000 description 1
- 230000020764 fibrinolysis Effects 0.000 description 1
- 229940124600 folk medicine Drugs 0.000 description 1
- 238000004108 freeze drying Methods 0.000 description 1
- 230000009931 harmful effect Effects 0.000 description 1
- 238000000265 homogenisation Methods 0.000 description 1
- 239000012535 impurity Substances 0.000 description 1
- 238000001802 infusion Methods 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 238000002803 maceration Methods 0.000 description 1
- 230000007721 medicinal effect Effects 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 239000012452 mother liquor Substances 0.000 description 1
- 239000002674 ointment Substances 0.000 description 1
- 239000000825 pharmaceutical preparation Substances 0.000 description 1
- 230000003285 pharmacodynamic effect Effects 0.000 description 1
- 229940012957 plasmin Drugs 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 230000007096 poisonous effect Effects 0.000 description 1
- 239000011148 porous material Substances 0.000 description 1
- 239000002244 precipitate Substances 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
- 238000012113 quantitative test Methods 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 229920005989 resin Polymers 0.000 description 1
- 239000011347 resin Substances 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 238000010025 steaming Methods 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 230000017260 vegetative to reproductive phase transition of meristem Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Plant Substances (AREA)
- Extraction Or Liquid Replacement (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7134172A FR2153171B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1971-09-22 | 1971-09-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE2246205A1 true DE2246205A1 (de) | 1973-03-29 |
Family
ID=9083337
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE2246205A Pending DE2246205A1 (de) | 1971-09-22 | 1972-09-21 | Verfahren zur gewinnung eines extrakts aus arnica montana |
Country Status (8)
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3319184A1 (de) * | 1983-05-27 | 1984-11-29 | Henkel Kgaa | Verfahren zur abtrennung von allergenen aus arnikablueten mittels co(pfeil abwaerts)2(pfeil abwaerts)-hochdruckextraktion |
| US5976547A (en) * | 1997-04-22 | 1999-11-02 | Niblick Pharmaceuticals, Inc. | Analgesic and antiphlogistic compositions and therapeutic wrap for topical delivery |
| FR2805158B1 (fr) * | 2000-02-18 | 2004-12-03 | L M D | Composition cosmetique ou medicamenteuse contenant une lactone sesquiterpenique ou un analogue pour traiter les desordres lies a la croissance pilaire, et son procede de preparation. |
| FR2807319B1 (fr) * | 2000-04-07 | 2004-10-22 | L M D | Composition cosmetique ou en tant que medicament contenant une lactone sesquiterpenique pour traiter les hematomes, et procede de traitement |
-
0
- BE BE789002D patent/BE789002A/xx unknown
-
1971
- 1971-09-22 FR FR7134172A patent/FR2153171B1/fr not_active Expired
-
1972
- 1972-09-21 US US00290826A patent/US3832343A/en not_active Expired - Lifetime
- 1972-09-21 DE DE2246205A patent/DE2246205A1/de active Pending
- 1972-09-22 NL NL7212833A patent/NL7212833A/xx unknown
- 1972-09-22 ZA ZA726481A patent/ZA726481B/xx unknown
- 1972-09-22 AU AU47019/72A patent/AU4701972A/en not_active Expired
- 1972-09-22 JP JP47095654A patent/JPS4856811A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| AU4701972A (en) | 1974-03-28 |
| US3832343A (en) | 1974-08-27 |
| ZA726481B (en) | 1973-06-27 |
| BE789002A (fr) | 1973-01-15 |
| FR2153171A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1973-05-04 |
| FR2153171B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1975-04-18 |
| NL7212833A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1973-03-26 |
| JPS4856811A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1973-08-09 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EP1267900B1 (de) | Emulsion enthaltend einen triterpen-haltigen pflanzenextrakt, verfahren zur herstellung der emulsion sowie zur gewinnung des pflanzenextraktes | |
| EP0599307B1 (de) | Johanniskraut-Trockenextrakt, Verfahren zu seiner Herstellung und seine Verwendung | |
| DE3705151A1 (de) | Warzenmittel | |
| DE19756848C2 (de) | Extrakte aus Blättern von Ginkgo biloba mit vermindertem Gehalt an 4'-O-Methylpyridoxin und Biflavonen | |
| AT391315B (de) | Verfahren zur herstellung von isosilybinfreiem silibinin | |
| CH642085A5 (de) | Verfahren zur gewinnung der polaren fraktion mit antipsoriatischer wirksamkeit eines extraktes aus farnpflanzen sowie ein gemaess diesem verfahren hergestelltes praeparat. | |
| DE10235465A1 (de) | Neue chinesische Kräuterzusammensetzung zur Verbesserung der Blutzirkulation sowie Verfahren zum Herstellen derselben | |
| CH650931A5 (de) | Extrakt von zedrach borken mit geschwulsthemmender wirkung und verfahren zu dessen herstellung. | |
| WO2005037299A1 (de) | Verfahren zur herstellung eines lagerstabilen extraktes aus efeublättern, sowie ein nach diesem verfahren hergestellter extrakt | |
| DE4028945A1 (de) | Kawa-kawa-extrakt, verfahren zu seiner herstellung und seine verwendung | |
| EP0904092B1 (de) | Gereinigter extrakt von harpagophytum procumbens und/oder harpagophytum zeyheri dence, verfahren zu seiner herstellung und seine verwendung | |
| EP1399173A2 (de) | Pharmazeutische zubereitung enthaltend wirkstoffe aus den pflanzen centella asiatica, mahonia aquifolium und viola tricolor | |
| DE2246205A1 (de) | Verfahren zur gewinnung eines extrakts aus arnica montana | |
| DE19603788B4 (de) | Wirkstoffextrakt aus Teufelskrallenwurzel, diesen enthaltendes human- oder veterinärmedizinisches Präparat, Verfahren zur Herstellung eines hochkonzentrierten Extraktes aus Radix Harpagophyti oder Herba und Radix Scrophularia sowie dessen Verwendung | |
| DE3504355A1 (de) | Mittel zur regenerierung der haut | |
| DE3111056A1 (de) | Verfahren zur gewinnung eines heilmittels mit wirkung bei arthritis und anderen krankheiten des osteolokomotorischen systems | |
| CH642039A5 (de) | Verfahren zur gewinnung natuerlicher terpene mit antipsoriatischer wirksamkeit und gemaess diesem verfahren hergestellte terpene. | |
| EP2956151B1 (de) | Verwendung von extrakten aus calendula zur behandlung und vorbeugung von störungen und beeinträchtigungen kognitiver und mentaler funktionen | |
| DE112017006865T5 (de) | Medizinischer Rohstoff aus einem Ginkgo-Extrakt und Verfahren zu dessen Herstellung | |
| DE3225597A1 (de) | Verfahren zur herstellung eines gewebepraeparates | |
| DE19818001C1 (de) | Verfahren zur schonenden Gewinnung von Extraktfraktionen aus Hypericum, diese enthaltende pharmazeutische Zubereitungen und Verwendung derselben | |
| DE10145885A1 (de) | Pharmazeutische Zusammensetzung zur Behandlung der Psoriasis | |
| CH695417A5 (de) | Verfahren zur Umsetzung von Alkaloiden. | |
| DE69222151T2 (de) | Therapeutische verwendung von pycnogenolen zur herstellung eines medikamentes mit antiinflammatorischer wirkung | |
| DE10066022B4 (de) | Pharmazeutische Zusammensetzung zur Behandlung der Neurodermitis |