DE2164619A1 - Neue 1,2,3,4-Tetrahydroisoichinolin-Derivate und Verfahren zu ihrer Herstellung - Google Patents

Neue 1,2,3,4-Tetrahydroisoichinolin-Derivate und Verfahren zu ihrer Herstellung

Info

Publication number
DE2164619A1
DE2164619A1 DE19712164619 DE2164619A DE2164619A1 DE 2164619 A1 DE2164619 A1 DE 2164619A1 DE 19712164619 DE19712164619 DE 19712164619 DE 2164619 A DE2164619 A DE 2164619A DE 2164619 A1 DE2164619 A1 DE 2164619A1
Authority
DE
Germany
Prior art keywords
radical
salt
halogen
hydroxy
nitro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
DE19712164619
Other languages
German (de)
English (en)
Inventor
Kunihiko Toyonaka; Zenno Hisanao Kyoto; Kishimoto Teiji Kawanishi; Tanaka (Japan)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Astellas Pharma Inc
Original Assignee
Fujisawa Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP12720070A external-priority patent/JPS4811715B1/ja
Priority claimed from JP12720170A external-priority patent/JPS4811716B1/ja
Priority claimed from JP12720270A external-priority patent/JPS4811717B1/ja
Priority claimed from JP45127199A external-priority patent/JPS4832114B1/ja
Priority claimed from JP12719870A external-priority patent/JPS4811714B1/ja
Application filed by Fujisawa Pharmaceutical Co Ltd filed Critical Fujisawa Pharmaceutical Co Ltd
Publication of DE2164619A1 publication Critical patent/DE2164619A1/de
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
    • C07D217/16—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals substituted by oxygen atoms
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE19712164619 1970-12-29 1971-12-24 Neue 1,2,3,4-Tetrahydroisoichinolin-Derivate und Verfahren zu ihrer Herstellung Ceased DE2164619A1 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP12720070A JPS4811715B1 (enExample) 1970-12-29 1970-12-29
JP12720170A JPS4811716B1 (enExample) 1970-12-29 1970-12-29
JP12720270A JPS4811717B1 (enExample) 1970-12-29 1970-12-29
JP45127199A JPS4832114B1 (enExample) 1970-12-29 1970-12-29
JP12719870A JPS4811714B1 (enExample) 1970-12-29 1970-12-29

Publications (1)

Publication Number Publication Date
DE2164619A1 true DE2164619A1 (de) 1972-07-13

Family

ID=27527131

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19712164619 Ceased DE2164619A1 (de) 1970-12-29 1971-12-24 Neue 1,2,3,4-Tetrahydroisoichinolin-Derivate und Verfahren zu ihrer Herstellung

Country Status (10)

Country Link
US (1) US3846432A (enExample)
AR (1) AR192232A1 (enExample)
AU (1) AU466429B2 (enExample)
CA (1) CA990726A (enExample)
DE (1) DE2164619A1 (enExample)
DK (1) DK128078B (enExample)
FR (1) FR2119989B1 (enExample)
GB (1) GB1374299A (enExample)
NL (1) NL7118047A (enExample)
SE (1) SE370941B (enExample)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4956988A (enExample) * 1972-10-05 1974-06-03
JPS5030886A (enExample) * 1973-07-20 1975-03-27
JPS5030885A (enExample) * 1973-07-20 1975-03-27
FR2460934A1 (fr) * 1979-07-02 1981-01-30 Chinoin Gyogyszer Es Vegyeszet Derives d'isoquinoleine contenant du soufre, procedes pour leur preparation et compositions pharmaceutiques les contenant

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3992260A (en) * 1970-12-23 1976-11-16 Agency Of Industrial Science & Technology Method for increasing yield of sucrose
JPS5734275B2 (enExample) * 1973-07-30 1982-07-22
AR204327A1 (es) * 1973-07-20 1975-12-22 Fujisawa Pharmaceutical Co Procedimiento para la preparacion de derivados de 1,2,3,4-tetrahidroisoquinolina
US3963725A (en) * 1973-07-20 1976-06-15 Fujisawa Pharmaceutical Co., Ltd. 1,2,3,4-Tetrahydroisoquinoline derivatives and the preparation thereof
DK496275A (da) * 1974-11-06 1976-05-07 Fujisawa Pharmaceutical Co Fremgangsmade til fremstilling af 1,2,3,4-tetrahydroisoquinoliner
US3966724A (en) * 1974-12-20 1976-06-29 Armour Pharmaceutical Company 1-(α-Aminomethylbenzyl)isoquinoline compounds
US3994891A (en) * 1974-12-20 1976-11-30 Armour Pharmaceutical Company Tetrahydroisoquinoline compounds
JPS609493A (ja) * 1983-06-30 1985-01-18 Kyowa Hakko Kogyo Co Ltd 新規生理活性物質ＭＹ３３６−ａおよびその製造法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2683146A (en) * 1950-02-07 1954-07-06 Searle & Co Tetrahydroisoquinolinium derivatives and methods for their production
US2663709A (en) * 1950-08-15 1953-12-22 Smith Kline French Lab 1-alkyl-6, 7-dihydroxy-1, 2, 3, 4-tetrahydroisoquinoline compounds
US3042671A (en) * 1959-10-07 1962-07-03 Pfizer & Co C Benzopyridocolines
GB1145254A (en) * 1965-03-18 1969-03-12 Bristol Myers Co Novel tetrahydroisoquinoline derivatives and a process for the preparation thereof
US3497516A (en) * 1965-12-08 1970-02-24 Tanabe Seiyaku Co Tetrahydroisoquinoline compounds and preparation thereof
GB1127525A (en) * 1966-04-01 1968-09-18 Pfizer Ltd Di- and tetrahydroisoquinoline derivatives
US3389141A (en) * 1966-05-16 1968-06-18 Bristol Myers Co 1-beta-aryloxyethyltetrahydro-isoquinolines
FR2028672A6 (enExample) * 1968-03-06 1970-10-16 Rhone Poulenc Sa
IL33480A (en) * 1968-12-10 1973-03-30 Tanabe Seiyaku Co 6,7-diacyloxy-tetrahydro-isoquinolines and their preparation

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4956988A (enExample) * 1972-10-05 1974-06-03
JPS5030886A (enExample) * 1973-07-20 1975-03-27
JPS5030885A (enExample) * 1973-07-20 1975-03-27
FR2460934A1 (fr) * 1979-07-02 1981-01-30 Chinoin Gyogyszer Es Vegyeszet Derives d'isoquinoleine contenant du soufre, procedes pour leur preparation et compositions pharmaceutiques les contenant

Also Published As

Publication number Publication date
NL7118047A (enExample) 1972-07-03
GB1374299A (en) 1974-11-20
CA990726A (en) 1976-06-08
DK128078B (da) 1974-02-25
US3846432A (en) 1974-11-05
AU466429B2 (en) 1975-10-30
FR2119989B1 (enExample) 1975-10-10
AR192232A1 (es) 1973-02-08
SE370941B (enExample) 1974-11-04
FR2119989A1 (enExample) 1972-08-11
AU3724471A (en) 1973-06-28

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Legal Events

Date Code Title Description
OD Request for examination
8131 Rejection