DE2149326A1 - 2,3-Dihydro-2-oxo-5-phenyl-1H-1,4-benzodiazepin-1-carboxamide und ein Verfahren zu deren Herstellung - Google Patents
2,3-Dihydro-2-oxo-5-phenyl-1H-1,4-benzodiazepin-1-carboxamide und ein Verfahren zu deren HerstellungInfo
- Publication number
- DE2149326A1 DE2149326A1 DE19712149326 DE2149326A DE2149326A1 DE 2149326 A1 DE2149326 A1 DE 2149326A1 DE 19712149326 DE19712149326 DE 19712149326 DE 2149326 A DE2149326 A DE 2149326A DE 2149326 A1 DE2149326 A1 DE 2149326A1
- Authority
- DE
- Germany
- Prior art keywords
- dihydro
- phenyl
- oxo
- benzodiazepine
- radical
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
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- SNICXCGAKADSCV-UHFFFAOYSA-N nicotine Natural products CN1CCCC1C1=CC=CN=C1 SNICXCGAKADSCV-UHFFFAOYSA-N 0.000 description 1
- 239000012299 nitrogen atmosphere Substances 0.000 description 1
- AKPLHCDWDRPJGD-UHFFFAOYSA-N nordazepam Chemical compound C12=CC(Cl)=CC=C2NC(=O)CN=C1C1=CC=CC=C1 AKPLHCDWDRPJGD-UHFFFAOYSA-N 0.000 description 1
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 description 1
- OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 description 1
- 238000012856 packing Methods 0.000 description 1
- 239000000312 peanut oil Substances 0.000 description 1
- 239000000825 pharmaceutical preparation Substances 0.000 description 1
- 235000021317 phosphate Nutrition 0.000 description 1
- 150000003013 phosphoric acid derivatives Chemical class 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 238000001953 recrystallisation Methods 0.000 description 1
- 235000005713 safflower oil Nutrition 0.000 description 1
- 239000003813 safflower oil Substances 0.000 description 1
- 229940125723 sedative agent Drugs 0.000 description 1
- 229910052711 selenium Inorganic materials 0.000 description 1
- 239000011669 selenium Substances 0.000 description 1
- 239000008159 sesame oil Substances 0.000 description 1
- 235000011803 sesame oil Nutrition 0.000 description 1
- 239000008117 stearic acid Substances 0.000 description 1
- 229960005453 strychnine Drugs 0.000 description 1
- 150000003467 sulfuric acid derivatives Chemical class 0.000 description 1
- 239000003765 sweetening agent Substances 0.000 description 1
- 239000003826 tablet Substances 0.000 description 1
- 239000011975 tartaric acid Substances 0.000 description 1
- 235000002906 tartaric acid Nutrition 0.000 description 1
- 150000003892 tartrate salts Chemical class 0.000 description 1
- 125000003944 tolyl group Chemical group 0.000 description 1
- 230000001256 tonic effect Effects 0.000 description 1
- 229940125725 tranquilizer Drugs 0.000 description 1
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 description 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
- 229940100445 wheat starch Drugs 0.000 description 1
- 239000002023 wood Substances 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
- C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
- C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
- C07D243/24—Oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US7816770A | 1970-10-05 | 1970-10-05 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE2149326A1 true DE2149326A1 (de) | 1972-04-06 |
Family
ID=22142348
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE19712149326 Withdrawn DE2149326A1 (de) | 1970-10-05 | 1971-10-02 | 2,3-Dihydro-2-oxo-5-phenyl-1H-1,4-benzodiazepin-1-carboxamide und ein Verfahren zu deren Herstellung |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US3718646A (enExample) |
| BE (1) | BE773515A (enExample) |
| DE (1) | DE2149326A1 (enExample) |
| FR (1) | FR2110217B1 (enExample) |
| GB (1) | GB1298300A (enExample) |
| IL (1) | IL37724A (enExample) |
| NL (1) | NL7113348A (enExample) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1538164A (en) * | 1976-05-05 | 1979-01-10 | Clin Midy | Benzodiazepine derivatives |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3236838A (en) * | 1964-06-09 | 1966-02-22 | Hoffmann La Roche | Certain 1-substituted-benzodiazepin-2-one compounds |
-
1970
- 1970-10-05 US US00078167A patent/US3718646A/en not_active Expired - Lifetime
-
1971
- 1971-09-10 GB GB42384/71A patent/GB1298300A/en not_active Expired
- 1971-09-14 IL IL37724A patent/IL37724A/xx unknown
- 1971-09-29 NL NL7113348A patent/NL7113348A/xx not_active Application Discontinuation
- 1971-10-02 DE DE19712149326 patent/DE2149326A1/de not_active Withdrawn
- 1971-10-04 FR FR7135694A patent/FR2110217B1/fr not_active Expired
- 1971-10-05 BE BE773515A patent/BE773515A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US3718646A (en) | 1973-02-27 |
| IL37724A (en) | 1976-02-29 |
| BE773515A (fr) | 1972-04-05 |
| NL7113348A (enExample) | 1972-04-07 |
| GB1298300A (en) | 1972-11-29 |
| FR2110217A1 (enExample) | 1972-06-02 |
| IL37724A0 (en) | 1971-11-29 |
| FR2110217B1 (enExample) | 1975-04-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| OD | Request for examination | ||
| 8130 | Withdrawal |