DE2140050A1 - Arzneimittelhaltiger stift - Google Patents
Arzneimittelhaltiger stiftInfo
- Publication number
- DE2140050A1 DE2140050A1 DE2140050A DE2140050A DE2140050A1 DE 2140050 A1 DE2140050 A1 DE 2140050A1 DE 2140050 A DE2140050 A DE 2140050A DE 2140050 A DE2140050 A DE 2140050A DE 2140050 A1 DE2140050 A1 DE 2140050A1
- Authority
- DE
- Germany
- Prior art keywords
- fatty acid
- acid ester
- ester mixture
- polyol fatty
- mixture
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 235000014113 dietary fatty acids Nutrition 0.000 claims description 17
- 239000000194 fatty acid Substances 0.000 claims description 17
- 229930195729 fatty acid Natural products 0.000 claims description 17
- 239000000203 mixture Substances 0.000 claims description 14
- 229920005862 polyol Polymers 0.000 claims description 11
- -1 polyol fatty acid ester Chemical class 0.000 claims description 11
- 229940079593 drug Drugs 0.000 claims description 6
- 239000003814 drug Substances 0.000 claims description 6
- 150000004665 fatty acids Chemical class 0.000 claims description 6
- 239000001993 wax Substances 0.000 claims description 6
- 238000000034 method Methods 0.000 claims description 5
- 239000007787 solid Substances 0.000 claims description 5
- 239000008186 active pharmaceutical agent Substances 0.000 claims description 4
- 150000002191 fatty alcohols Chemical class 0.000 claims description 4
- 125000004432 carbon atom Chemical group C* 0.000 claims description 3
- 229930195733 hydrocarbon Natural products 0.000 claims description 3
- 150000002430 hydrocarbons Chemical class 0.000 claims description 3
- 238000004519 manufacturing process Methods 0.000 claims description 3
- 230000000699 topical effect Effects 0.000 claims description 3
- 239000004480 active ingredient Substances 0.000 claims description 2
- 230000000844 anti-bacterial effect Effects 0.000 claims description 2
- 230000002421 anti-septic effect Effects 0.000 claims description 2
- 239000003899 bactericide agent Substances 0.000 claims description 2
- 150000001735 carboxylic acids Chemical class 0.000 claims description 2
- 239000000645 desinfectant Substances 0.000 claims description 2
- 239000003589 local anesthetic agent Substances 0.000 claims description 2
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims 3
- 239000003246 corticosteroid Substances 0.000 claims 1
- 229940126601 medicinal product Drugs 0.000 claims 1
- 150000002148 esters Chemical class 0.000 description 9
- 239000000155 melt Substances 0.000 description 8
- BXWNKGSJHAJOGX-UHFFFAOYSA-N n-hexadecyl alcohol Natural products CCCCCCCCCCCCCCCCO BXWNKGSJHAJOGX-UHFFFAOYSA-N 0.000 description 7
- 235000013871 bee wax Nutrition 0.000 description 6
- 239000012166 beeswax Substances 0.000 description 6
- 239000012188 paraffin wax Substances 0.000 description 6
- 150000001875 compounds Chemical class 0.000 description 5
- 229960000541 cetyl alcohol Drugs 0.000 description 4
- 230000000694 effects Effects 0.000 description 4
- GLDOVTGHNKAZLK-UHFFFAOYSA-N octadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCCCO GLDOVTGHNKAZLK-UHFFFAOYSA-N 0.000 description 4
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 3
- 239000000344 soap Substances 0.000 description 3
- 241000283153 Cetacea Species 0.000 description 2
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
- 230000001476 alcoholic effect Effects 0.000 description 2
- BLFLLBZGZJTVJG-UHFFFAOYSA-N benzocaine Chemical compound CCOC(=O)C1=CC=C(N)C=C1 BLFLLBZGZJTVJG-UHFFFAOYSA-N 0.000 description 2
- YMKDRGPMQRFJGP-UHFFFAOYSA-M cetylpyridinium chloride Chemical compound [Cl-].CCCCCCCCCCCCCCCC[N+]1=CC=CC=C1 YMKDRGPMQRFJGP-UHFFFAOYSA-M 0.000 description 2
- 229940110456 cocoa butter Drugs 0.000 description 2
- 235000019868 cocoa butter Nutrition 0.000 description 2
- LQZZUXJYWNFBMV-UHFFFAOYSA-N dodecan-1-ol Chemical compound CCCCCCCCCCCCO LQZZUXJYWNFBMV-UHFFFAOYSA-N 0.000 description 2
- 239000000499 gel Substances 0.000 description 2
- JYGXADMDTFJGBT-VWUMJDOOSA-N hydrocortisone Chemical compound O=C1CC[C@]2(C)[C@H]3[C@@H](O)C[C@](C)([C@@](CC4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 JYGXADMDTFJGBT-VWUMJDOOSA-N 0.000 description 2
- 150000002632 lipids Chemical class 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- GOQYKNQRPGWPLP-UHFFFAOYSA-N n-heptadecyl alcohol Natural products CCCCCCCCCCCCCCCCCO GOQYKNQRPGWPLP-UHFFFAOYSA-N 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- HLZKNKRTKFSKGZ-UHFFFAOYSA-N tetradecan-1-ol Chemical compound CCCCCCCCCCCCCCO HLZKNKRTKFSKGZ-UHFFFAOYSA-N 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- DTOUUUZOYKYHEP-UHFFFAOYSA-N 1,3-bis(2-ethylhexyl)-5-methyl-1,3-diazinan-5-amine Chemical compound CCCCC(CC)CN1CN(CC(CC)CCCC)CC(C)(N)C1 DTOUUUZOYKYHEP-UHFFFAOYSA-N 0.000 description 1
- TWJNQYPJQDRXPH-UHFFFAOYSA-N 2-cyanobenzohydrazide Chemical compound NNC(=O)C1=CC=CC=C1C#N TWJNQYPJQDRXPH-UHFFFAOYSA-N 0.000 description 1
- 235000013162 Cocos nucifera Nutrition 0.000 description 1
- 244000060011 Cocos nucifera Species 0.000 description 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical class Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 1
- NNJVILVZKWQKPM-UHFFFAOYSA-N Lidocaine Chemical compound CCN(CC)CC(=O)NC1=C(C)C=CC=C1C NNJVILVZKWQKPM-UHFFFAOYSA-N 0.000 description 1
- 235000021360 Myristic acid Nutrition 0.000 description 1
- TUNFSRHWOTWDNC-UHFFFAOYSA-N Myristic acid Natural products CCCCCCCCCCCCCC(O)=O TUNFSRHWOTWDNC-UHFFFAOYSA-N 0.000 description 1
- 239000005662 Paraffin oil Substances 0.000 description 1
- 229920003171 Poly (ethylene oxide) Polymers 0.000 description 1
- 229920002125 Sokalan® Polymers 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 150000007513 acids Chemical class 0.000 description 1
- 229920000615 alginic acid Polymers 0.000 description 1
- 235000010443 alginic acid Nutrition 0.000 description 1
- 239000003513 alkali Substances 0.000 description 1
- NUZWLKWWNNJHPT-UHFFFAOYSA-N anthralin Chemical compound C1C2=CC=CC(O)=C2C(=O)C2=C1C=CC=C2O NUZWLKWWNNJHPT-UHFFFAOYSA-N 0.000 description 1
- 230000001166 anti-perspirative effect Effects 0.000 description 1
- 239000003213 antiperspirant Substances 0.000 description 1
- 229940064004 antiseptic throat preparations Drugs 0.000 description 1
- 229960000686 benzalkonium chloride Drugs 0.000 description 1
- CADWTSSKOVRVJC-UHFFFAOYSA-N benzyl(dimethyl)azanium;chloride Chemical compound [Cl-].C[NH+](C)CC1=CC=CC=C1 CADWTSSKOVRVJC-UHFFFAOYSA-N 0.000 description 1
- KGBXLFKZBHKPEV-UHFFFAOYSA-N boric acid Chemical compound OB(O)O KGBXLFKZBHKPEV-UHFFFAOYSA-N 0.000 description 1
- 239000004327 boric acid Substances 0.000 description 1
- 229960001927 cetylpyridinium chloride Drugs 0.000 description 1
- 239000003610 charcoal Substances 0.000 description 1
- 229960002172 chlorquinaldol Drugs 0.000 description 1
- GPTXWRGISTZRIO-UHFFFAOYSA-N chlorquinaldol Chemical compound ClC1=CC(Cl)=C(O)C2=NC(C)=CC=C21 GPTXWRGISTZRIO-UHFFFAOYSA-N 0.000 description 1
- YMTMADLUXIRMGX-RFPWEZLHSA-N clocortolone Chemical compound C1([C@@H](F)C2)=CC(=O)C=C[C@]1(C)[C@]1(Cl)[C@@H]2[C@@H]2C[C@@H](C)[C@H](C(=O)CO)[C@@]2(C)C[C@@H]1O YMTMADLUXIRMGX-RFPWEZLHSA-N 0.000 description 1
- 239000002537 cosmetic Substances 0.000 description 1
- 239000002781 deodorant agent Substances 0.000 description 1
- 229960003957 dexamethasone Drugs 0.000 description 1
- UREBDLICKHMUKA-CXSFZGCWSA-N dexamethasone Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(F)[C@@H]1[C@@H]1C[C@@H](C)[C@@](C(=O)CO)(O)[C@@]1(C)C[C@@H]2O UREBDLICKHMUKA-CXSFZGCWSA-N 0.000 description 1
- OGPWIDANBSLJPC-RFPWEZLHSA-N diflucortolone Chemical compound C1([C@@H](F)C2)=CC(=O)C=C[C@]1(C)[C@]1(F)[C@@H]2[C@@H]2C[C@@H](C)[C@H](C(=O)CO)[C@@]2(C)C[C@@H]1O OGPWIDANBSLJPC-RFPWEZLHSA-N 0.000 description 1
- 229960004091 diflucortolone Drugs 0.000 description 1
- 150000002334 glycols Chemical class 0.000 description 1
- 239000004519 grease Substances 0.000 description 1
- ACGUYXCXAPNIKK-UHFFFAOYSA-N hexachlorophene Chemical compound OC1=C(Cl)C=C(Cl)C(Cl)=C1CC1=C(O)C(Cl)=CC(Cl)=C1Cl ACGUYXCXAPNIKK-UHFFFAOYSA-N 0.000 description 1
- 229960004068 hexachlorophene Drugs 0.000 description 1
- 229960004867 hexetidine Drugs 0.000 description 1
- 229960000890 hydrocortisone Drugs 0.000 description 1
- 239000000017 hydrogel Substances 0.000 description 1
- 238000010348 incorporation Methods 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 229940057995 liquid paraffin Drugs 0.000 description 1
- 229960005015 local anesthetics Drugs 0.000 description 1
- 239000004200 microcrystalline wax Substances 0.000 description 1
- 235000019808 microcrystalline wax Nutrition 0.000 description 1
- 230000003020 moisturizing effect Effects 0.000 description 1
- 239000003921 oil Substances 0.000 description 1
- 239000005022 packaging material Substances 0.000 description 1
- 125000000913 palmityl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 239000001814 pectin Substances 0.000 description 1
- 235000010987 pectin Nutrition 0.000 description 1
- 229920001277 pectin Polymers 0.000 description 1
- 239000002304 perfume Substances 0.000 description 1
- 229920001515 polyalkylene glycol Chemical class 0.000 description 1
- 229920001521 polyalkylene glycol ether Polymers 0.000 description 1
- 229960005205 prednisolone Drugs 0.000 description 1
- OIGNJSKKLXVSLS-VWUMJDOOSA-N prednisolone Chemical compound O=C1C=C[C@]2(C)[C@H]3[C@@H](O)C[C@](C)([C@@](CC4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 OIGNJSKKLXVSLS-VWUMJDOOSA-N 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 229920006395 saturated elastomer Polymers 0.000 description 1
- 229930195734 saturated hydrocarbon Natural products 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 229940072358 xylocaine Drugs 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/02—Suppositories; Bougies; Bases therefor; Ovules
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
Priority Applications (11)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| BE787243D BE787243A (fr) | 1971-08-05 | Forme de presentation de medicaments | |
| DE2140050A DE2140050A1 (de) | 1971-08-05 | 1971-08-05 | Arzneimittelhaltiger stift |
| CH1122672A CH566785A5 (enExample) | 1971-08-05 | 1972-07-27 | |
| AU45153/72A AU470244B2 (en) | 1971-08-05 | 1972-07-31 | Stick compositions anda process for their manufacture |
| NL7210682A NL7210682A (enExample) | 1971-08-05 | 1972-08-03 | |
| SE7210200A SE394795B (sv) | 1971-08-05 | 1972-08-04 | Sett att framstella stift innehallande lekemedelsubstanser |
| CA148,791A CA977679A (en) | 1971-08-05 | 1972-08-04 | Stick compositions and a process for producing same |
| FR7228237A FR2150734B1 (enExample) | 1971-08-05 | 1972-08-04 | |
| AT676172A AT342202B (de) | 1971-08-05 | 1972-08-04 | Verfahren zur herstellung von stiftmassen fur dermatologische und kosmetische zwecke |
| ZA725360A ZA725360B (en) | 1971-08-05 | 1972-08-04 | Stick compositions and a process for their manufacture |
| GB3673372A GB1397095A (en) | 1971-08-05 | 1972-08-07 | Stick compositions and a process for their manufacture |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2140050A DE2140050A1 (de) | 1971-08-05 | 1971-08-05 | Arzneimittelhaltiger stift |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE2140050A1 true DE2140050A1 (de) | 1973-02-15 |
Family
ID=5816362
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE2140050A Pending DE2140050A1 (de) | 1971-08-05 | 1971-08-05 | Arzneimittelhaltiger stift |
Country Status (11)
| Country | Link |
|---|---|
| AT (1) | AT342202B (enExample) |
| AU (1) | AU470244B2 (enExample) |
| BE (1) | BE787243A (enExample) |
| CA (1) | CA977679A (enExample) |
| CH (1) | CH566785A5 (enExample) |
| DE (1) | DE2140050A1 (enExample) |
| FR (1) | FR2150734B1 (enExample) |
| GB (1) | GB1397095A (enExample) |
| NL (1) | NL7210682A (enExample) |
| SE (1) | SE394795B (enExample) |
| ZA (1) | ZA725360B (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10250944B3 (de) * | 2002-10-31 | 2004-06-09 | Cell Center Cologne Gmbh | Verwendung eines Stifts zur Applikation von Pflege- oder Wirkstoffen in die Nase |
-
0
- BE BE787243D patent/BE787243A/xx unknown
-
1971
- 1971-08-05 DE DE2140050A patent/DE2140050A1/de active Pending
-
1972
- 1972-07-27 CH CH1122672A patent/CH566785A5/xx not_active IP Right Cessation
- 1972-07-31 AU AU45153/72A patent/AU470244B2/en not_active Expired
- 1972-08-03 NL NL7210682A patent/NL7210682A/xx not_active Application Discontinuation
- 1972-08-04 FR FR7228237A patent/FR2150734B1/fr not_active Expired
- 1972-08-04 ZA ZA725360A patent/ZA725360B/xx unknown
- 1972-08-04 CA CA148,791A patent/CA977679A/en not_active Expired
- 1972-08-04 SE SE7210200A patent/SE394795B/xx unknown
- 1972-08-04 AT AT676172A patent/AT342202B/de not_active IP Right Cessation
- 1972-08-07 GB GB3673372A patent/GB1397095A/en not_active Expired
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10250944B3 (de) * | 2002-10-31 | 2004-06-09 | Cell Center Cologne Gmbh | Verwendung eines Stifts zur Applikation von Pflege- oder Wirkstoffen in die Nase |
| DE10250944B9 (de) * | 2002-10-31 | 2004-09-16 | Cell Center Cologne Gmbh | Verwendung eines Stifts zur Applikation von Pflege- oder Wirkstoffen in die Nase |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2150734A1 (enExample) | 1973-04-13 |
| BE787243A (fr) | 1973-02-05 |
| SE394795B (sv) | 1977-07-11 |
| GB1397095A (en) | 1975-06-11 |
| CH566785A5 (enExample) | 1975-09-30 |
| ZA725360B (en) | 1973-04-25 |
| AU470244B2 (en) | 1976-03-11 |
| FR2150734B1 (enExample) | 1975-06-20 |
| ATA676172A (de) | 1977-07-15 |
| CA977679A (en) | 1975-11-11 |
| NL7210682A (enExample) | 1973-02-07 |
| AT342202B (de) | 1978-03-28 |
| AU4515372A (en) | 1974-02-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| OHA | Expiration of time for request for examination |