DE2123653C3 - Vorrichtung zur Herstellung eines Elutionsmittels - Google Patents

Vorrichtung zur Herstellung eines Elutionsmittels

Info

Publication number
DE2123653C3
DE2123653C3 DE2123653A DE2123653A DE2123653C3 DE 2123653 C3 DE2123653 C3 DE 2123653C3 DE 2123653 A DE2123653 A DE 2123653A DE 2123653 A DE2123653 A DE 2123653A DE 2123653 C3 DE2123653 C3 DE 2123653C3
Authority
DE
Germany
Prior art keywords
liquid
valve
valves
mixing chamber
concentration
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE2123653A
Other languages
German (de)
English (en)
Other versions
DE2123653A1 (de
DE2123653B2 (de
Inventor
Howard Lloyd Ashmead
Sydnor Hummer Newark Del. Byrne Jun.
John Peter Wilmington Del. Wolf
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
EIDP Inc
Original Assignee
EI Du Pont de Nemours and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by EI Du Pont de Nemours and Co filed Critical EI Du Pont de Nemours and Co
Publication of DE2123653A1 publication Critical patent/DE2123653A1/de
Publication of DE2123653B2 publication Critical patent/DE2123653B2/de
Application granted granted Critical
Publication of DE2123653C3 publication Critical patent/DE2123653C3/de
Expired legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/80—Forming a predetermined ratio of the substances to be mixed
    • B01F35/81—Forming mixtures with changing ratios or gradients
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/28—Control of physical parameters of the fluid carrier
    • G01N30/34—Control of physical parameters of the fluid carrier of fluid composition, e.g. gradient
    • G—PHYSICS
    • G05—CONTROLLING; REGULATING
    • G05D—SYSTEMS FOR CONTROLLING OR REGULATING NON-ELECTRIC VARIABLES
    • G05D11/00—Control of flow ratio
    • G05D11/02—Controlling ratio of two or more flows of fluid or fluent material
    • G05D11/13—Controlling ratio of two or more flows of fluid or fluent material characterised by the use of electric means
    • G05D11/135—Controlling ratio of two or more flows of fluid or fluent material characterised by the use of electric means by sensing at least one property of the mixture
    • G05D11/138—Controlling ratio of two or more flows of fluid or fluent material characterised by the use of electric means by sensing at least one property of the mixture by sensing the concentration of the mixture, e.g. measuring pH value
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/28—Control of physical parameters of the fluid carrier
    • G01N30/34—Control of physical parameters of the fluid carrier of fluid composition, e.g. gradient
    • G01N2030/347—Control of physical parameters of the fluid carrier of fluid composition, e.g. gradient mixers
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T137/00—Fluid handling
    • Y10T137/2931—Diverse fluid containing pressure systems
    • Y10T137/3112—Main line flow displaces additive from shunt reservoir

Landscapes

  • Chemical & Material Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Automation & Control Theory (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Accessories For Mixers (AREA)
DE2123653A 1970-05-12 1971-05-12 Vorrichtung zur Herstellung eines Elutionsmittels Expired DE2123653C3 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US3663370A 1970-05-12 1970-05-12

Publications (3)

Publication Number Publication Date
DE2123653A1 DE2123653A1 (de) 1971-11-25
DE2123653B2 DE2123653B2 (de) 1981-06-11
DE2123653C3 true DE2123653C3 (de) 1982-04-29

Family

ID=21889723

Family Applications (1)

Application Number Title Priority Date Filing Date
DE2123653A Expired DE2123653C3 (de) 1970-05-12 1971-05-12 Vorrichtung zur Herstellung eines Elutionsmittels

Country Status (8)

Country Link
US (1) US3712513A (enExample)
JP (1) JPS5019959B1 (enExample)
CH (1) CH529585A (enExample)
DE (1) DE2123653C3 (enExample)
FR (1) FR2091465A5 (enExample)
GB (1) GB1340093A (enExample)
NL (1) NL7106434A (enExample)
SE (1) SE383567B (enExample)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS52133294A (en) * 1976-05-01 1977-11-08 Nippon Bunko Kogyo Kk Pumping system and liquid transfer process for liquid chromatography
US4391390A (en) * 1981-01-21 1983-07-05 Howard Arthur G Chemical-mixing and dispensing apparatus
US4496245A (en) * 1983-03-07 1985-01-29 International Business Machines Corporation Liquid chromatography proportioning valve and mixer
JPS6396552A (ja) * 1986-10-14 1988-04-27 Suntory Ltd 生体高分子の工業的分離法、その方法に使用する装置
US4859342A (en) * 1986-10-14 1989-08-22 Suntory Limited Process for industrially separating biopolymers
US4954253A (en) * 1987-05-14 1990-09-04 Nauchno-Tekhnicheskoe Objedinenie Akademii Nauk Sssr Device for preparing a gradient solution for a high-pressure liquid chromatograph
US5004351A (en) * 1988-04-18 1991-04-02 Minnesota Mining & Manufacturing Company Reaction injection molding machine
US5067886A (en) * 1988-04-18 1991-11-26 Minnesota Mining And Manufacturing Company Reaction injection molding machine
SE9600796D0 (sv) * 1996-02-29 1996-02-29 Pharmacia Biotech Ab A method of preparing a liquid mixture
EP1376121A1 (en) * 2002-06-29 2004-01-02 Agilent Technologies Inc. a Delaware Corporation Pumping arrangement
US7507337B2 (en) * 2004-09-03 2009-03-24 Symyx Technologies, Inc. System and method for rapid chromatography with fluid temperature and mobile phase composition control
US7425263B2 (en) * 2006-08-29 2008-09-16 Cryobiophysica Multi-component, simultaneous, independent multi-gradient system for liquid chromatography
EP2269055B1 (en) * 2008-04-21 2011-11-09 GE Healthcare Bio-Sciences AB Preparation of liquid mixtures
JP5961112B2 (ja) * 2009-09-25 2016-08-02 ジーイー・ヘルスケア・バイオサイエンス・アクチボラグ 液体混合物の調製方法及びシステム
WO2011162666A1 (en) * 2010-06-23 2011-12-29 Ge Healthcare Bio-Sciences Ab Method of preparing liquid mixtures
GB2530341A (en) * 2014-09-22 2016-03-23 Stratec Biomedical Ag Liquid preparation unit
US10850236B2 (en) * 2015-08-31 2020-12-01 Palo Alto Research Center Incorporated Low dispersion, fast response mixing device
CN109126528B (zh) * 2018-08-07 2021-04-06 浙江海洋大学 基于数据库技术的透明土混合液配置装置及方法
EP4605741A1 (en) * 2022-10-18 2025-08-27 Equilibar, LLC Pumpless system for gradient buffer production

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US571350A (en) * 1896-11-17 Henry w
US3123252A (en) * 1964-03-03 kuntz
US2219763A (en) * 1938-02-21 1940-10-29 Robert H Cartier Proportioner
US2362607A (en) * 1943-07-24 1944-11-14 Mckays Company Feeder
US2850213A (en) * 1955-09-27 1958-09-02 Cole Albert Multiple carbonated drink dispensing apparatus
US2878969A (en) * 1955-12-19 1959-03-24 Donald G Griswold Batch feed apparatus
US3130870A (en) * 1960-04-11 1964-04-28 British Petroleum Co Metering system
NL262675A (enExample) * 1961-03-22
US3193143A (en) * 1962-10-18 1965-07-06 Maieli Vincent Automatic liquid dispensing device
DK100525C (da) * 1963-07-01 1964-12-07 Drostholm F H Fremgangsmåde ved kontrollering af den i tidsrum af forudbestemt varighed afgivne mængde af en eller flere tyktflydende væsker samt apparat til udøvelse af fremgangsmåden.
US3446057A (en) * 1966-10-14 1969-05-27 Varian Associates Method and apparatus for chromatography

Also Published As

Publication number Publication date
DE2123653A1 (de) 1971-11-25
DE2123653B2 (de) 1981-06-11
SE383567B (sv) 1976-03-15
FR2091465A5 (enExample) 1972-01-14
CH529585A (de) 1972-10-31
NL7106434A (enExample) 1971-11-16
JPS5019959B1 (enExample) 1975-07-10
GB1340093A (en) 1973-12-05
US3712513A (en) 1973-01-23

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Legal Events

Date Code Title Description
C3 Grant after two publication steps (3rd publication)
8339 Ceased/non-payment of the annual fee