DE19900674A1 - Bindungspartner für 5-HT5-Rezeptoren zur Migränebehandlung - Google Patents
Bindungspartner für 5-HT5-Rezeptoren zur MigränebehandlungInfo
- Publication number
- DE19900674A1 DE19900674A1 DE19900674A DE19900674A DE19900674A1 DE 19900674 A1 DE19900674 A1 DE 19900674A1 DE 19900674 A DE19900674 A DE 19900674A DE 19900674 A DE19900674 A DE 19900674A DE 19900674 A1 DE19900674 A1 DE 19900674A1
- Authority
- DE
- Germany
- Prior art keywords
- binding
- receptors
- binding partner
- affinity
- indicates
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
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Classifications
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- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
- G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
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- A—HUMAN NECESSITIES
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- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A61K31/4045—Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/48—Ergoline derivatives, e.g. lysergic acid, ergotamine
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Hematology (AREA)
- Neurology (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Cell Biology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cardiology (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Heart & Thoracic Surgery (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Pain & Pain Management (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Priority Applications (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19900674A DE19900674A1 (de) | 1999-01-11 | 1999-01-11 | Bindungspartner für 5-HT5-Rezeptoren zur Migränebehandlung |
| PCT/EP2000/000142 WO2000041472A2 (fr) | 1999-01-11 | 2000-01-11 | Partenaires de liaison pour les recepteurs 5-ht5 utilises pour le traitement de la migraine |
| AU22891/00A AU2289100A (en) | 1999-01-11 | 2000-01-11 | Binding partners for 5-ht5-receptors for the treatment of migraine |
| EP00901526A EP1144050A2 (fr) | 1999-01-11 | 2000-01-11 | Partenaires de liaison pour les recepteurs 5-ht5 utilises pour le traitement de la migraine |
| MXPA01006986A MXPA01006986A (es) | 1999-01-11 | 2000-01-11 | Contrapartes de union de los receptores 5-ht5 para tratamiento de migrana. |
| CA2359360A CA2359360C (fr) | 1999-01-11 | 2000-01-11 | Methode de criblage in vitro permettant d'identifier des partenaires de liaison selective pour recepteurs 5-ht5 |
| CNB008046107A CN1321635C (zh) | 1999-01-11 | 2000-01-11 | 用于偏头痛治疗的5－ht5受体的结合配偶体 |
| JP2000593096A JP2002540063A (ja) | 1999-01-11 | 2000-01-11 | 偏頭痛治療のための５−ｈｔ５受容体のための結合パートナー |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19900674A DE19900674A1 (de) | 1999-01-11 | 1999-01-11 | Bindungspartner für 5-HT5-Rezeptoren zur Migränebehandlung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE19900674A1 true DE19900674A1 (de) | 2000-07-13 |
Family
ID=7893919
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE19900674A Withdrawn DE19900674A1 (de) | 1999-01-11 | 1999-01-11 | Bindungspartner für 5-HT5-Rezeptoren zur Migränebehandlung |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP1144050A2 (fr) |
| JP (1) | JP2002540063A (fr) |
| CN (1) | CN1321635C (fr) |
| AU (1) | AU2289100A (fr) |
| CA (1) | CA2359360C (fr) |
| DE (1) | DE19900674A1 (fr) |
| MX (1) | MXPA01006986A (fr) |
| WO (1) | WO2000041472A2 (fr) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102004008141A1 (de) | 2004-02-19 | 2005-09-01 | Abbott Gmbh & Co. Kg | Guanidinverbindungen und ihre Verwendung als Bindungspartner für 5-HT5-Rezeptoren |
| EP2308852A1 (fr) | 2005-08-21 | 2011-04-13 | Abbott GmbH & Co. KG | Composés 5-cycle-heteroaromates et leur utilisation en tant que partenaires de liaison des récepteurs 5-HT5 |
| EP1917244A2 (fr) | 2005-08-24 | 2008-05-07 | Abbott GmbH & Co. KG | Composes guanidine a substitution hetaryl et utilisation en tant que partenaires de liaison pour des recepteurs de 5-ht5 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU8770282A (en) * | 1981-08-27 | 1983-03-03 | Shaun R. Coughlin | Composition for the treatment of atherosclerosis |
| US5360735A (en) * | 1992-01-08 | 1994-11-01 | Synaptic Pharmaceutical Corporation | DNA encoding a human 5-HT1F receptor, vectors, and host cells |
| FR2693200B1 (fr) * | 1992-07-01 | 1994-08-19 | Inst Nat Sante Rech Med | Nouveaux polypeptides ayant une activité de récepteur sérotoninergique, acides nucléiques codant pour ces polypeptides et utilisations. |
| FR2701265B1 (fr) * | 1993-02-09 | 1995-04-07 | Inst Nat Sante Rech Med | Nouveaux polypeptides ayant une activité de récepteur sérotoninergique, acides nucléiques codant pour ces polypeptides et utilisations. |
-
1999
- 1999-01-11 DE DE19900674A patent/DE19900674A1/de not_active Withdrawn
-
2000
- 2000-01-11 EP EP00901526A patent/EP1144050A2/fr not_active Ceased
- 2000-01-11 MX MXPA01006986A patent/MXPA01006986A/es not_active IP Right Cessation
- 2000-01-11 AU AU22891/00A patent/AU2289100A/en not_active Abandoned
- 2000-01-11 WO PCT/EP2000/000142 patent/WO2000041472A2/fr active Application Filing
- 2000-01-11 CA CA2359360A patent/CA2359360C/fr not_active Expired - Fee Related
- 2000-01-11 CN CNB008046107A patent/CN1321635C/zh not_active Expired - Fee Related
- 2000-01-11 JP JP2000593096A patent/JP2002540063A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CN1342070A (zh) | 2002-03-27 |
| WO2000041472A3 (fr) | 2001-10-11 |
| AU2289100A (en) | 2000-08-01 |
| EP1144050A2 (fr) | 2001-10-17 |
| CA2359360C (fr) | 2012-11-27 |
| JP2002540063A (ja) | 2002-11-26 |
| MXPA01006986A (es) | 2002-09-18 |
| CA2359360A1 (fr) | 2000-07-20 |
| WO2000041472A2 (fr) | 2000-07-20 |
| CN1321635C (zh) | 2007-06-20 |
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