DE19757516A1 - Modifizierte Nukleinsäureanaloga - Google Patents

Modifizierte Nukleinsäureanaloga

Info

Publication number
DE19757516A1
DE19757516A1 DE19757516A DE19757516A DE19757516A1 DE 19757516 A1 DE19757516 A1 DE 19757516A1 DE 19757516 A DE19757516 A DE 19757516A DE 19757516 A DE19757516 A DE 19757516A DE 19757516 A1 DE19757516 A1 DE 19757516A1
Authority
DE
Germany
Prior art keywords
group
probe
nucleic acids
acid
probes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19757516A
Other languages
German (de)
English (en)
Inventor
Frank Dr Bergmann
Herbert Von Der Dr Eltz
Rupert Dr Herrmann
Stefanie Dr Koehler
Volker Dr Schlueter
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Roche Diagnostics GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roche Diagnostics GmbH filed Critical Roche Diagnostics GmbH
Priority to DE19757516A priority Critical patent/DE19757516A1/de
Priority to PCT/EP1998/008317 priority patent/WO1999033867A2/fr
Priority to EP98966833A priority patent/EP0996631A1/fr
Publication of DE19757516A1 publication Critical patent/DE19757516A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • C07K14/003—Peptide-nucleic acids (PNAs)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6832—Enhancement of hybridisation reaction
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DE19757516A 1997-12-23 1997-12-23 Modifizierte Nukleinsäureanaloga Withdrawn DE19757516A1 (de)

Priority Applications (3)

Application Number Priority Date Filing Date Title
DE19757516A DE19757516A1 (de) 1997-12-23 1997-12-23 Modifizierte Nukleinsäureanaloga
PCT/EP1998/008317 WO1999033867A2 (fr) 1997-12-23 1998-12-18 Analogues d'acide nucleique modifies
EP98966833A EP0996631A1 (fr) 1997-12-23 1998-12-18 Analogues d'acide nucleique modifies

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19757516A DE19757516A1 (de) 1997-12-23 1997-12-23 Modifizierte Nukleinsäureanaloga

Publications (1)

Publication Number Publication Date
DE19757516A1 true DE19757516A1 (de) 1999-06-24

Family

ID=7853170

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19757516A Withdrawn DE19757516A1 (de) 1997-12-23 1997-12-23 Modifizierte Nukleinsäureanaloga

Country Status (3)

Country Link
EP (1) EP0996631A1 (fr)
DE (1) DE19757516A1 (fr)
WO (1) WO1999033867A2 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1251183A2 (fr) * 2001-04-18 2002-10-23 Exiqon A/S Des sondes assistantes supérieures pour la détéction d'une séquence cible utilisant une sonde de capture

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10019135A1 (de) 2000-04-18 2001-10-31 Aventis Pharma Gmbh Polyamidnukleinsäure-Derivate, Mittel und Verfahren zu ihrer Herstellung
DE10019136A1 (de) * 2000-04-18 2001-10-31 Aventis Pharma Gmbh Polyamidnukleinsäure-Derivate, Mittel und Verfahren zu ihrer Herstellung

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2284208A (en) * 1993-11-25 1995-05-31 Pna Diagnostics As Nucleic acid analogues with a chelating functionality for metal ions
ATE222589T1 (de) * 1994-10-06 2002-09-15 Isis Pharmaceuticals Inc Peptid-nukleinsäure-konjugate
WO1996035705A1 (fr) * 1995-05-10 1996-11-14 Isis Pharmaceuticals, Inc. Inhibition, au moyen d'une invasion de brins oligomeres, de l'activation par transcription induite par un facteur de transcription

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1251183A2 (fr) * 2001-04-18 2002-10-23 Exiqon A/S Des sondes assistantes supérieures pour la détéction d'une séquence cible utilisant une sonde de capture
EP1251183A3 (fr) * 2001-04-18 2003-12-10 Exiqon A/S Des sondes assistantes supérieures pour la détéction d'une séquence cible utilisant une sonde de capture

Also Published As

Publication number Publication date
WO1999033867A2 (fr) 1999-07-08
WO1999033867A3 (fr) 1999-09-02
EP0996631A1 (fr) 2000-05-03

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Legal Events

Date Code Title Description
8139 Disposal/non-payment of the annual fee